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  1. Article ; Online: Correction to: Environmental Integrants Affecting the Spreadability of SARS‑CoV‑2.

    Islam, Muhammad Torequl

    Food and environmental virology

    2021  Volume 13, Issue 2, Page(s) 281

    Language English
    Publishing date 2021-04-24
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2487173-4
    ISSN 1867-0342 ; 1867-0334
    ISSN (online) 1867-0342
    ISSN 1867-0334
    DOI 10.1007/s12560-021-09478-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Environmental Integrants Affecting the Spreadability of SARS-CoV-12.

    Islam, Muhammad Torequl

    Food and environmental virology

    2020  Volume 12, Issue 3, Page(s) 278–279

    MeSH term(s) Betacoronavirus/pathogenicity ; Betacoronavirus/physiology ; COVID-19 ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Environmental Microbiology ; Humans ; Pandemics ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country United States
    Document type Letter
    ZDB-ID 2487173-4
    ISSN 1867-0342 ; 1867-0334
    ISSN (online) 1867-0342
    ISSN 1867-0334
    DOI 10.1007/s12560-020-09435-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Angiostatic effects of ascorbic acid: current status and future perspectives.

    Islam, Muhammad Torequl

    Angiogenesis

    2020  Volume 23, Issue 3, Page(s) 275–277

    Abstract: Anti-angiogenesis effect of ascorbic acid (AA) is still controversial. However, most of the scientific evidence suggests that AA has anti-angiogenesis effects on a number of test systems, including laboratory animals, human beings, and their derived cell ...

    Abstract Anti-angiogenesis effect of ascorbic acid (AA) is still controversial. However, most of the scientific evidence suggests that AA has anti-angiogenesis effects on a number of test systems, including laboratory animals, human beings, and their derived cell lines. The information provided in this paper suggests that AA may be a hopeful angiostatic agent for the treatment of cancer.
    MeSH term(s) Angiogenesis Inhibitors/therapeutic use ; Animals ; Ascorbic Acid/therapeutic use ; Humans ; Neoplasms/blood supply ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neovascularization, Pathologic/drug therapy ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology
    Chemical Substances Angiogenesis Inhibitors ; Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2020-04-02
    Publishing country Germany
    Document type Letter ; Review
    ZDB-ID 1484717-6
    ISSN 1573-7209 ; 0969-6970
    ISSN (online) 1573-7209
    ISSN 0969-6970
    DOI 10.1007/s10456-020-09719-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Antipyretic effect of phytol, possibly via 5KIR-dependent COX-2 inhibition pathway.

    Islam, Muhammad Torequl

    Inflammopharmacology

    2019  Volume 27, Issue 4, Page(s) 857–862

    Abstract: Aims: This study is aimed at the evaluation of antipyretic effect of PHY in yeast-induced hyperthermia rats. Additionally, possible mechanism of antipyretic action of PHY has been also studied by molecular docking study.: Methods: Adult male Wistar ... ...

    Abstract Aims: This study is aimed at the evaluation of antipyretic effect of PHY in yeast-induced hyperthermia rats. Additionally, possible mechanism of antipyretic action of PHY has been also studied by molecular docking study.
    Methods: Adult male Wistar albino rats were treated with PHY at 100, 150 and 200 mg/kg in 0.05% Tween-80 dissolved in 0.9% NaCl solution. PHY was also given at 200 mg/kg with ibuprofen (IBU) 12.5 mg/kg (p.o.) or paracetamol (PARA) 100 mg/kg (p.o.) to see the combined effect of PHY in animals. In silico study of PHY was performed against cyclooxygenase (COX) enzymes (COX-1 and -2) proteins.
    Results: PHY exhibited the antipyretic effect in febrile rats in a dose and time dependent manner. PHY 200 mg/kg co-treated with IBU12.5 or PARA100 exhibited greater antipyretic effect than the PHY or NSAIDs individual groups. Data from the computational study reveal that 5KIR of COX-2 is the most efficient receptor protein to which PHY interacts.
    Conclusion: PHY attributed an antipyretic effect, possibly via 5KIR-dependent COX-2 inhibition pathway.
    MeSH term(s) Acetaminophen/pharmacology ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Antipyretics/pharmacology ; Cyclooxygenase 1/metabolism ; Cyclooxygenase 2/metabolism ; Cyclooxygenase Inhibitors/pharmacology ; Fever/drug therapy ; Fever/metabolism ; Ibuprofen/pharmacology ; Male ; Phytol/pharmacology ; Rats ; Rats, Wistar
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Antipyretics ; Cyclooxygenase Inhibitors ; Phytol (150-86-7) ; Acetaminophen (362O9ITL9D) ; Cyclooxygenase 1 (EC 1.14.99.1) ; Cyclooxygenase 2 (EC 1.14.99.1) ; Ptgs2 protein, rat (EC 1.14.99.1) ; Ibuprofen (WK2XYI10QM)
    Language English
    Publishing date 2019-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1080058-x
    ISSN 1568-5608 ; 0925-4692
    ISSN (online) 1568-5608
    ISSN 0925-4692
    DOI 10.1007/s10787-019-00574-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Phytochemical analysis and biological investigation of

    Juhi, Umme Habiba / El-Nashar, Heba A S / Al Faruq, Abdullah / Bhuia, Md Shimul / Sultana, Irin / Alam, Syedul / Abuyousef, Farah / Saleh, Na'il / El-Shazly, Mohamed / Islam, Muhammad Torequl

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1366889

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1366889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Phytochemical information and pharmacological activities of Okra (Abelmoschus esculentus): A literature-based review.

    Islam, Muhammad Torequl

    Phytotherapy research : PTR

    2018  Volume 33, Issue 1, Page(s) 72–80

    Abstract: This review aimed at summarizing phytochemical reports and biological activities of Abelmoschus esculentus L. from the database sources. For this, an up-to-date search was made in the PubMed, Science Direct, MedLine, Scopus, and Google Scholar. The ... ...

    Abstract This review aimed at summarizing phytochemical reports and biological activities of Abelmoschus esculentus L. from the database sources. For this, an up-to-date search was made in the PubMed, Science Direct, MedLine, Scopus, and Google Scholar. The findings suggest that A. esculentus contains various nutrients and important phytochemicals. It possesses a number of important biological activities, including antioxidant, anti-inflammatory and immunomodulatory, antibacterial, anticancer, antidiabetic, organ protective, and neuropharmacological activities. Moreover, the plant also has lipid-lowering, trypsin inhibitory, hemagglutinating, antiadhesive, and antifatigue activities. The fruit and seeds are well tolerated in humans and other animals. In conclusion, A. esculentus may be one of the best sources of pharmacologically active lead compounds. More research is necessary on its toxicogenetic effects in animals.
    MeSH term(s) Abelmoschus/chemistry ; Animals ; Antioxidants/chemistry ; Humans ; Phytochemicals/chemistry ; Plant Extracts/chemistry
    Chemical Substances Antioxidants ; Phytochemicals ; Plant Extracts
    Language English
    Publishing date 2018-10-22
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.6212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evaluating the Quality of Raw Chocolate as an Alternative to Commercial Products

    Radosław Kowalski / Marek Rosochacki / Jakub Wyrostek / Muhammad Torequl Islam

    Applied Sciences, Vol 13, Iss 1274, p

    2023  Volume 1274

    Abstract: The aim of this presented study was the sensory evaluation, the analysis of the nutritional composition, and the analysis of the content of health-promoting ingredients, i.e., the total phenolic compounds and the total flavonoids, in raw chocolate (made ... ...

    Abstract The aim of this presented study was the sensory evaluation, the analysis of the nutritional composition, and the analysis of the content of health-promoting ingredients, i.e., the total phenolic compounds and the total flavonoids, in raw chocolate (made exclusively from unroasted cocoa beans, cane sugar, and cocoa butter) in comparison to classic commercial chocolates available in the consumer market. The research showed that raw chocolate, compared to commercial chocolates, contained less carbohydrates (39.6% in raw chocolate and 42.7% and 53.7% in commercial chocolate, respectively), was characterized by a higher content of total phenolic compounds (22.08 mg GAE/g in raw chocolate and 9.25 and 7.87 mg GAE/g in commercial chocolates, respectively), had a a higher content of total flavonoids (8.75 mg ECE/g in raw chocolate and 4.43 mg/g and 3.83 mg ECE/g in commercial chocolates, respectively), and also had a higher total antioxidant activity (172.16 μM TE/g in raw chocolate and 132.60 and 63.76 μM TE/g in commercial chocolates, respectively). In the sensory assessment, raw chocolate received lower ranks than commercial chocolates, especially in the case of the most important discriminant in the entire evaluation, i.e., taste, which was unquestionably related to the lower content of carbohydrates. However, currently, it is necessary to reduce the consumption of sugar, which, when excessively present in the diet, is the cause of many diseases. However, in the sensory evaluation for the criteria “external appearance—shape” and “external appearance—surface condition,” the raw chocolate received the highest marks.
    Keywords raw chocolate ; chemical composition ; antioxidant activity ; sensory evaluation ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 660
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Diterpenes and Their Derivatives as Potential Anticancer Agents.

    Islam, Muhammad Torequl

    Phytotherapy research : PTR

    2017  Volume 31, Issue 5, Page(s) 691–712

    Abstract: As therapeutic tools, diterpenes and their derivatives have gained much attention of the medicinal scientists nowadays. It is due to their pledging and important biological activities. This review congregates the anticancer diterpenes. For this, a search ...

    Abstract As therapeutic tools, diterpenes and their derivatives have gained much attention of the medicinal scientists nowadays. It is due to their pledging and important biological activities. This review congregates the anticancer diterpenes. For this, a search was made with selected keywords in PubMed, Science Direct, Web of Science, Scopus, The American Chemical Society and miscellaneous databases from January 2012 to January 2017 for the published articles. A total 28, 789 published articles were seen. Among them, 240 were included in this study. More than 250 important anticancer diterpenes and their derivatives were seen in the databases, acting in the different pathways. Some of them are already under clinical trials, while others are in the nonclinical and/or pre-clinical trials. In conclusion, diterpenes may be one of the lead molecules in the treatment of cancer. Copyright © 2017 John Wiley & Sons, Ltd.
    MeSH term(s) Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Diterpenes/chemistry ; Diterpenes/pharmacology ; Humans ; Neoplasms/drug therapy ; Phytochemicals/chemistry ; Phytochemicals/pharmacology
    Chemical Substances Antineoplastic Agents ; Diterpenes ; Phytochemicals
    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.5800
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Radiation interactions with biological systems.

    Islam, Muhammad Torequl

    International journal of radiation biology

    2017  Volume 93, Issue 5, Page(s) 487–493

    Abstract: Purpose: The use of radiation, especially ionizing radiation (IR), is currently attracting great attention in the field of medical sciences. However, it should be mentioned that IR has both beneficial and harmful effects in biological systems. This ... ...

    Abstract Purpose: The use of radiation, especially ionizing radiation (IR), is currently attracting great attention in the field of medical sciences. However, it should be mentioned that IR has both beneficial and harmful effects in biological systems. This review aims to focus on IR-mediated physiological events in a mechanistic way.
    Materials and methods: Evidence from the databases, mainly from PUBMED and SCIENCE DIRECT were considered.
    Results: IR directly and/or with their lyses products (indirect) causes oxidative stresses to biological systems. These activities may be localized and systematic. Otherwise, IR-induced non-/multi-targeted effects are also evident. IR in diagnosis and cancer radiotherapy is well-known. Reactive species produced by IR are not only beneficial, but also can exert harmful effects in a biological system such as aging, genetic instability and mutagenicity, membrane lysis and cell death, alteration of enzymatic activity and metabolic events, mitochondrial dysfunction, and even cancer. Additionally, DNA adducts formation, after IR-induced DNA breakage, is a cause of blockage of DNA repair capability with an increase in cellular radiosensitivity. These may allow cellular ruin even at low IR levels.
    Conclusion: Dependent on the dose, duration of action and quality, IR plays diverse roles in biological systems.
    MeSH term(s) Animals ; DNA Damage/physiology ; Dose-Response Relationship, Radiation ; Humans ; Models, Biological ; Oxidative Stress/physiology ; Oxidative Stress/radiation effects ; Radiation Dosage ; Radiation, Ionizing ; Reactive Oxygen Species/metabolism
    Chemical Substances Reactive Oxygen Species
    Language English
    Publishing date 2017-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3065-x
    ISSN 1362-3095 ; 0020-7616 ; 0955-3002
    ISSN (online) 1362-3095
    ISSN 0020-7616 ; 0955-3002
    DOI 10.1080/09553002.2017.1286050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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