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  1. Article: Beneficial effects of Chinese herbs in the treatment of fatty liver diseases.

    Panyod, Suraphan / Sheen, Lee-Yan

    Journal of traditional and complementary medicine

    2020  Volume 10, Issue 3, Page(s) 260–267

    Abstract: Eating habits and lifestyle directly impact general health. Consumption of fat- and sugar-rich foods and alcohol increase the risk of developing fatty liver disease. The prevalence of fatty liver disease is markedly critical, and its pathogenesis and ... ...

    Abstract Eating habits and lifestyle directly impact general health. Consumption of fat- and sugar-rich foods and alcohol increase the risk of developing fatty liver disease. The prevalence of fatty liver disease is markedly critical, and its pathogenesis and progression are complicated. Chinese herbal medicine has been used to treat and prevent human diseases through-out history, and is a rich source of biologically active substances with unique curative properties. More recently, Chinese herbs and their extracts have been identified as a novel source of potential therapeutic agents in the prevention and treatment of fatty liver disease. Beneficial effects of these herbal medicines mean that they can be classified as novel candidates for the treatment and prevention of both alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD), in place of conventional allopathic treatments. In this review, we explore the current literature related to herbal medicines used for the treatment of or protection against fatty liver diseases and describe their mechanisms of action.
    Language English
    Publishing date 2020-03-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2709698-1
    ISSN 2225-4110
    ISSN 2225-4110
    DOI 10.1016/j.jtcme.2020.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Beneficial effects of Chinese herbs in the treatment of fatty liver diseases

    Suraphan Panyod / Lee-Yan Sheen

    Journal of Traditional and Complementary Medicine, Vol 10, Iss 3, Pp 260-

    2020  Volume 267

    Abstract: Eating habits and lifestyle directly impact general health. Consumption of fat- and sugar-rich foods and alcohol increase the risk of developing fatty liver disease. The prevalence of fatty liver disease is markedly critical, and its pathogenesis and ... ...

    Abstract Eating habits and lifestyle directly impact general health. Consumption of fat- and sugar-rich foods and alcohol increase the risk of developing fatty liver disease. The prevalence of fatty liver disease is markedly critical, and its pathogenesis and progression are complicated. Chinese herbal medicine has been used to treat and prevent human diseases through-out history, and is a rich source of biologically active substances with unique curative properties. More recently, Chinese herbs and their extracts have been identified as a novel source of potential therapeutic agents in the prevention and treatment of fatty liver disease. Beneficial effects of these herbal medicines mean that they can be classified as novel candidates for the treatment and prevention of both alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD), in place of conventional allopathic treatments. In this review, we explore the current literature related to herbal medicines used for the treatment of or protection against fatty liver diseases and describe their mechanisms of action.
    Keywords Fatty liver disease ; Alcoholic fatty liver disease ; Non-alcoholic fatty liver disease ; AFLD ; NAFLD ; High-fat diet ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Article: Korean red ginseng water extract produces antidepressant-like effects through involving monoamines and brain-derived neurotrophic factor in rats.

    Chou, Tzu-Wen / Huang, Huai-Syuan / Panyod, Suraphan / Huang, Yun-Ju / Sheen, Lee-Yan

    Journal of ginseng research

    2023  Volume 47, Issue 4, Page(s) 552–560

    Abstract: Background: Ginseng Radix (: Methods: The antidepressant potential of the UCMS model was evaluated using the sucrose preference test and open field tests. The behavioral findings were further corroborated by the assessment of neurotransmitters and ... ...

    Abstract Background: Ginseng Radix (
    Methods: The antidepressant potential of the UCMS model was evaluated using the sucrose preference test and open field tests. The behavioral findings were further corroborated by the assessment of neurotransmitters and their metabolites from the prefrontal cortex and hippocampus of rats. Three doses of KGE (50, 100, and 200 mg/kg) were orally administered during the experiment. Furthermore, the mechanism underlying the antidepressant-like action of KGE was examined by measuring the levels of brain-derived neurotrophic factor (BDNF)/CREB, nuclear factor erythroid 2-related factor 2 (Nrf2), and Kelch-like ECH-associated protein 1 (Keap1) proteins in the prefrontal cortex of UCMS-exposed rats.
    Results: KGE treatment normalized UCMS-induced depression-related behaviors. Neurotransmitter studies conducted after completing behavioral experiments demonstrated that KGE caused a reduction in the ratio of serotonin and dopamine, indicating a decrease in serotonin and dopamine turnover. Moreover, the expression of BDNF, Nrf2, Keap1 and AKT were markedly increased by KGE in the prefrontal cortex of depressed rats.
    Conclusion: Our results provide evidence that KGE and its constituents exert antidepressant effects that mediate the dopaminergic and serotonergic systems and expression of BDNF protein in an animal model.
    Language English
    Publishing date 2023-01-09
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2765273-7
    ISSN 2093-4947 ; 1226-8453
    ISSN (online) 2093-4947
    ISSN 1226-8453
    DOI 10.1016/j.jgr.2023.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial note: Gut microbiota and health.

    Ho, Chi-Tang / Wu, Ming-Shiang / Panyod, Suraphan / Chang, Ashley Chiung-Fang / Isidoro, Ciro / Sheen, Lee-Yan

    Journal of traditional and complementary medicine

    2023  Volume 13, Issue 2, Page(s) 105–106

    Language English
    Publishing date 2023-03-13
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2709698-1
    ISSN 2225-4110
    ISSN 2225-4110
    DOI 10.1016/j.jtcme.2023.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial note

    Chi-Tang Ho / Ming-Shiang Wu / Suraphan Panyod / Ashley Chiung-Fang Chang / Ciro Isidoro / Lee-Yan Sheen

    Journal of Traditional and Complementary Medicine, Vol 13, Iss 2, Pp 105-

    Gut microbiota and health

    2023  Volume 106

    Keywords Medicine ; R
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article ; Online: Korean red ginseng water extract produces antidepressant-like effects through involving monoamines and brain-derived neurotrophic factor in rats

    Chou, Tzu-wen / Huang, Huai-Syuan / Panyod, Suraphan / Huang, Yun-Ju / Sheen, Lee-Yan

    Journal of Ginseng Research. 2023 July, v. 47, no. 4 p.552-560

    2023  

    Abstract: Ginseng Radix (Panax ginseng Meyer, Araliaceae) has been used medicinally to treat the brain and nervous system problems worldwide. Recent studies have revealed physiological effects that could potentially benefit cognitive performance or mood. The ... ...

    Abstract Ginseng Radix (Panax ginseng Meyer, Araliaceae) has been used medicinally to treat the brain and nervous system problems worldwide. Recent studies have revealed physiological effects that could potentially benefit cognitive performance or mood. The present study aimed to investigate the antidepressant effects of Korean red ginseng water extract (KGE) and its active component in an unpredictable chronic mild stress (UCMS)-induced animal model and elucidate the underlying mechanisms. The antidepressant potential of the UCMS model was evaluated using the sucrose preference test and open field tests. The behavioral findings were further corroborated by the assessment of neurotransmitters and their metabolites from the prefrontal cortex and hippocampus of rats. Three doses of KGE (50, 100, and 200 mg/kg) were orally administered during the experiment. Furthermore, the mechanism underlying the antidepressant-like action of KGE was examined by measuring the levels of brain-derived neurotrophic factor (BDNF)/CREB, nuclear factor erythroid 2-related factor 2 (Nrf2), and Kelch-like ECH-associated protein 1 (Keap1) proteins in the prefrontal cortex of UCMS-exposed rats. KGE treatment normalized UCMS-induced depression-related behaviors. Neurotransmitter studies conducted after completing behavioral experiments demonstrated that KGE caused a reduction in the ratio of serotonin and dopamine, indicating a decrease in serotonin and dopamine turnover. Moreover, the expression of BDNF, Nrf2, Keap1 and AKT were markedly increased by KGE in the prefrontal cortex of depressed rats. Our results provide evidence that KGE and its constituents exert antidepressant effects that mediate the dopaminergic and serotonergic systems and expression of BDNF protein in an animal model.
    Keywords Panax ginseng ; animal models ; antidepressants ; cognition ; dopamine ; emotions ; hippocampus ; metabolites ; neurotransmitters ; prefrontal cortex ; research ; serotonin ; sucrose ; Korean red ginseng water extract ; unpredictable chronic mild stress ; brain-derived neurotrophic factor
    Language English
    Dates of publication 2023-07
    Size p. 552-560.
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version ; Use and reproduction
    ZDB-ID 2765273-7
    ISSN 2093-4947 ; 1226-8453
    ISSN (online) 2093-4947
    ISSN 1226-8453
    DOI 10.1016/j.jgr.2023.01.003
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective.

    Panyod, Suraphan / Ho, Chi-Tang / Sheen, Lee-Yan

    Journal of traditional and complementary medicine

    2020  Volume 10, Issue 4, Page(s) 420–427

    Abstract: A novel coronavirus disease (COVID-19), transmitted from humans to humans, has rapidly become the pandemic responsible for the current global health crisis. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is said ...

    Abstract A novel coronavirus disease (COVID-19), transmitted from humans to humans, has rapidly become the pandemic responsible for the current global health crisis. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is said to be of zoonotic origin. This review describes the etiology and signs and symptoms as well as the current allopathic therapy for COVID-19. Additionally, findings of previous studies on the immunomodulatory effects and antiviral activities of particular foods and herbs on influenza virus and coronaviruses have been collated, with the aim of promoting the use of dietary therapy and herbal medicine as COVID-19 preventive therapies, while specific drugs and vaccines are yet to be discovered or are still under development. The volume of existing reports is irrefutable evidence that foods and herbs possess a potential antiviral ability against SARS-CoV-2 and can prevent COVID-19. Foods and herbs could be used as dietary or complementary therapy to prevent infection and strengthen immunity, as antiviral agents for masks, as disinfectants to curb aerosol transmission, or as sanitizing agents to disinfect surfaces. However, these hypotheses need to be experimentally verified for SARS-CoV-2 and COVID-19 patients.
    Keywords covid19
    Language English
    Publishing date 2020-05-30
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2709698-1
    ISSN 2225-4110
    ISSN 2225-4110
    DOI 10.1016/j.jtcme.2020.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Dietary therapy and herbal medicine for COVID-19 prevention

    Suraphan Panyod / Chi-Tang Ho / Lee-Yan Sheen

    Journal of Traditional and Complementary Medicine, Vol 10, Iss 4, Pp 420-

    A review and perspective

    2020  Volume 427

    Abstract: A novel coronavirus disease (COVID-19), transmitted from humans to humans, has rapidly become the pandemic responsible for the current global health crisis. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is said ...

    Abstract A novel coronavirus disease (COVID-19), transmitted from humans to humans, has rapidly become the pandemic responsible for the current global health crisis. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is said to be of zoonotic origin. This review describes the etiology and signs and symptoms as well as the current allopathic therapy for COVID-19. Additionally, findings of previous studies on the immunomodulatory effects and antiviral activities of particular foods and herbs on influenza virus and coronaviruses have been collated, with the aim of promoting the use of dietary therapy and herbal medicine as COVID-19 preventive therapies, while specific drugs and vaccines are yet to be discovered or are still under development. The volume of existing reports is irrefutable evidence that foods and herbs possess a potential antiviral ability against SARS-CoV-2 and can prevent COVID-19. Foods and herbs could be used as dietary or complementary therapy to prevent infection and strengthen immunity, as antiviral agents for masks, as disinfectants to curb aerosol transmission, or as sanitizing agents to disinfect surfaces. However, these hypotheses need to be experimentally verified for SARS-CoV-2 and COVID-19 patients.
    Keywords COVID-19 ; SARS-CoV-2 ; Coronavirus ; Dietary therapy ; Herbal medicine ; Herbs ; Medicine ; R ; covid19
    Subject code 610
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  9. Article ; Online: Modulation of gut microbiota by foods and herbs to prevent cardiovascular diseases

    Suraphan Panyod / Wei-Kai Wu / Chieh-Chang Chen / Ming-Shiang Wu / Chi-Tang Ho / Lee-Yan Sheen

    Journal of Traditional and Complementary Medicine, Vol 13, Iss 2, Pp 107-

    2023  Volume 118

    Abstract: Dietary nutrients are associated with the development of cardiovascular disease (CVD) both through traditional pathways (inducing hyperlipidemia and chronic inflammation) and through the emergence of a metaorganism-pathogenesis pathway (through the gut ... ...

    Abstract Dietary nutrients are associated with the development of cardiovascular disease (CVD) both through traditional pathways (inducing hyperlipidemia and chronic inflammation) and through the emergence of a metaorganism-pathogenesis pathway (through the gut microbiota, its metabolites, and host). Several molecules from food play an important role as CVD risk-factor precursors either themselves or through the metabolism of the gut microbiome. Animal-based dietary proteins are the primary source of CVD risk-factor precursors; however, some plants also possess these precursors, though at relatively low levels compared with animal-source food products. Various medications have been developed to treat CVD through the gut-microbiota–circulation axis, and they exhibit potent effects in CVD treatment. Nevertheless, such medicines are still being improved, and there are many research gaps that need to be addressed. Furthermore, some medications have unpleasant or adverse effects. Numerous foods and herbs impart beneficial effects upon health and disease. In the past decade, many studies have focused on treating and preventing CVD by modulating the gut microbiota and their metabolites. This review provides an overview of the available information, summarizes current research related to the gut-microbiota–heart axis, enumerates the foods and herbs that are CVD-risk precursors, and illustrates how metabolites become CVD risk factors through the metabolism of gut microbiota. Moreover, we present perspectives on the application of foods and herbs—including prebiotics, probiotics, synbiotics, postbiotics, and antibiotic-like substances—as CVD prevention agents to modulate gut microbiota by inhibiting gut-derived CVD risk factors. Taxonomy (classification by EVISE): Cardiovascular disease, gut microbiota, herbal medicine, preventive medicine, dietary therapy, nutrition supplements.
    Keywords Gut microbiota ; Microbial metabolite ; Cardiovascular disease ; Food ; Herbs ; Medicine ; R
    Subject code 910
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  10. Article ; Online: Dietary therapy and herbal medicine for COVID-19 prevention

    Panyod, Suraphan / Ho, Chi-Tang / Sheen, Lee-Yan

    Journal of Traditional and Complementary Medicine

    A review and perspective

    2020  Volume 10, Issue 4, Page(s) 420–427

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2709698-1
    ISSN 2225-4110
    ISSN 2225-4110
    DOI 10.1016/j.jtcme.2020.05.004
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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