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  1. Article ; Online: Multiple Reversed Halo Sign on Chest CT in COVID-19 Pneumonia.

    Aslan, Serdar

    Archivos de bronconeumologia

    2020  Volume 57, Page(s) 69

    Language English
    Publishing date 2020-11-09
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2020.10.018
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  2. Article ; Online: Simultaneous UPLC Assay for Oxitropium Bromide and Formoterol Fumarate Dihydrate in Pressurized Metered Dose Inhaler Products for Chronic Obstructive Pulmonary Disease.

    Seckin, Serdar / Saglik Aslan, Serap

    Journal of AOAC International

    2024  Volume 107, Issue 2, Page(s) 242–247

    Abstract: Backround: Oxitropium bromide (OB) and formoterol fumarate dihydrate (FFD) are inhaler molecules that are widely used in the treatment of chronic lung diseases.: Objective: The goal of this work was to create a reversed phase-ultra performance liquid ...

    Abstract Backround: Oxitropium bromide (OB) and formoterol fumarate dihydrate (FFD) are inhaler molecules that are widely used in the treatment of chronic lung diseases.
    Objective: The goal of this work was to create a reversed phase-ultra performance liquid chromatography (RP-UPLC) technique for assay and identification of OB and FFD, as well as identification and estimate of its associated compounds in pressurized metered dose inhaler product (pMDI).
    Method: Separation of oxitropium and formoterol peaks were enhanced on a C18 (50 × 2.1 mm × 1.7 μm) UPLC column with ethylene-bridged-hybrid technology, The mobile phase consists of buffer (0.07 M KH2PO4) and acetonitrile (80:20, v/v). The detector wavelength of 210 nm, flow rate of pump 0.6 mL/min, and oven temperature for column were set at 25°C. The injection volume was 10 μL. The method run time was 2 min. The mobile phase was used as the solvent.
    Results: Retention times (RTs) were 0.5 min for OB and 1.0 min for FFD. The assay analysis was linear range for all analytes within the range for concentrations 0.03-14.8 µg/mL of OB, 0.01-0.88 µg/mL of FFD. LOD values and LOQ values 0.009 and 0.026 µg/mL for OB and 0.003 and 0.009 µg/mL for FFD, respectively. Recoveries were obtained at 96.3% for OB and 97.2% for FFD. Precisions values were (as RSD, %) ≤1.5%.
    Conclusions: With the UPLC method developed and validated according to the current ICH guidelines, it is possible to simultaneously detect OB and FFD of assay analysis in pMDI products accurately, precisely and selectively, independent of the matrix effect.
    Highlights: The present method is the first method in the literature based on the UPLC method for this purpose. The UPLC method is a time-saving method, it provides a faster and cheaper technique than the high performance liquid chromatography (HPLC) method.
    MeSH term(s) Humans ; Bronchodilator Agents/therapeutic use ; Chromatography, High Pressure Liquid/methods ; Ethanolamines/analysis ; Ethanolamines/therapeutic use ; Formoterol Fumarate/therapeutic use ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Metered Dose Inhalers ; Nebulizers and Vaporizers ; Scopolamine Derivatives
    Chemical Substances oxitropium (8G15T83E6I) ; Bronchodilator Agents ; Ethanolamines ; Formoterol Fumarate (W34SHF8J2K) ; Scopolamine Derivatives
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1103149-9
    ISSN 1944-7922 ; 1060-3271
    ISSN (online) 1944-7922
    ISSN 1060-3271
    DOI 10.1093/jaoacint/qsad134
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  3. Article: Prostatic embryonal rhabdomyosarcoma in an adult.

    Onder, Ramazan O / Aslan, Serdar / Demirelli, Erhan

    British journal of hospital medicine (London, England : 2005)

    2024  Volume 85, Issue 2, Page(s) 1

    MeSH term(s) Adult ; Humans ; Rhabdomyosarcoma, Embryonal/diagnosis
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2023.0340
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  4. Article ; Online: Lymphocytic Interstitial Pneumonia in a Man with Human Immunodeficiency Virus Infection.

    Tasdemir, Merve Nur / Aslan, Serdar

    Revista da Sociedade Brasileira de Medicina Tropical

    2023  Volume 56, Page(s) e0055

    MeSH term(s) Male ; Humans ; Lung Diseases, Interstitial/diagnostic imaging ; Lung Diseases, Interstitial/etiology ; HIV Infections/complications
    Language English
    Publishing date 2023-06-02
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0055-2023
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  5. Article ; Online: Hepatic hydatid cyst ruptured from the transdiaphragmatic path to the pleural cavity.

    Önder, Ramazan Orkun / Aslan, Serdar

    Revista da Sociedade Brasileira de Medicina Tropical

    2023  Volume 56, Page(s) e0610

    MeSH term(s) Humans ; Echinococcosis, Hepatic/diagnostic imaging ; Echinococcosis, Hepatic/surgery ; Pleural Cavity ; Rupture
    Language English
    Publishing date 2023-02-20
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0610-2022
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  6. Article ; Online: Lymphocytic Interstitial Pneumonia in a Man with Human Immunodeficiency Virus Infection

    Merve Nur Tasdemir / Serdar Aslan

    Revista da Sociedade Brasileira de Medicina Tropical, Vol

    2023  Volume 56

    Keywords Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A Rare Cause of Obstructive Jaundice and Pancreatitis; Lemmel's Syndrome.

    Aslan, Serdar / Önder, Ramazan Orkun

    Current medical imaging

    2023  

    Abstract: Introduction/background: Lemmel's syndrome is defined as obstructive jaundice due to a PDD in the absence of choledocholithiasis or a neoplasm. The most common cause is the presence of PDD which arise within 2-3 cm from the ampulla of Vater. Currently, ... ...

    Abstract Introduction/background: Lemmel's syndrome is defined as obstructive jaundice due to a PDD in the absence of choledocholithiasis or a neoplasm. The most common cause is the presence of PDD which arise within 2-3 cm from the ampulla of Vater. Currently, there are very few case reports of this condition, which was first named in 1934 after Dr. Gerhard Lemmel.
    Case presentation: A 74-year-old female patient presented to the emergency department with complaints of abdominal pain and jaundice, and also had signs of pancreatitis, with laboratory results showing elevated liver and pancreatic enzymes and hyperbilirubinemia. We present a case of a patient who was diagnosed with Lemmel's syndrome after abdominal CT, MRCP, and ERCP.
    Conclusion: Although rare, it is imperative for physicians to recognize this syndrome in order to deliver prompt care. Because making the correct diagnosis in these patients is very important for correct treatment and preventing the development of complications.
    Language English
    Publishing date 2023-03-06
    Publishing country United Arab Emirates
    Document type Case Reports
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/1573405619666230306104924
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  8. Article: Prevalence of Bladder Cancers Incidentally Detected During Multiparametric MRI Scans of the Prostate Gland and the Clinical Significance of Scoring Them According to VI-RADS: A Pictorial Single-Centre Study.

    Onder, Ramazan Orkun / Aslan, Serdar / Bekci, Tümay

    Journal of the Belgian Society of Radiology

    2024  Volume 108, Issue 1, Page(s) 7

    Abstract: Purpose: To determine the prevalence of incidentally detected bladder cancers (BCs) on multiparametric magnetic resonance imaging (mpMRI) of the prostate and to highlight the clinical importance of scoring them according to the Vesical Imaging-Reporting ...

    Abstract Purpose: To determine the prevalence of incidentally detected bladder cancers (BCs) on multiparametric magnetic resonance imaging (mpMRI) of the prostate and to highlight the clinical importance of scoring them according to the Vesical Imaging-Reporting and Data System (VI-RADS).
    Materials and methods: VI-RADS scores for incidental bladder lesions on mpMRI of the prostate were collected in 1693 patients with elevated prostate-specific antigen but no hematuria. The study included 19 patients with 28 incidental bladder lesions.
    Results: During this period, 39 incidental bladder lesions were found in 30 patients, representing 1.7% of cases. Of the 28 lesions, 11 were categorized by VI-RADS as VI-RADS 1, 14 as VI-RADS 2, 1 as VI-RADS 3, 1 as VI-RADS 4, and 1 as VI-RADS 5. Histopathological examination revealed 1 benign lesion, 24 non-muscle invasive BCs, and 3 muscle-invasive BCs in the 19 patients. Impressively, 97% of the incidental lesions detected by prostate mpMRI and categorized by VI-RADS were BCs without apparent prostate cancer invasion. Notably, 93% of these lesions were consistent with histopathological findings of muscle invasion and extravesical spread.
    Conclusion: Our study concludes the prevalence 1% incidental BC in prostate mpMRI. The research underscores a thorough bladder examination during prostate MRI scans. Utilizing mpMRI assists in distinguishing varying BC stages, aiding treatment decisions, and patient outcomes. VI-RADS categorization aligns with histopathological results, enhancing diagnosis, and healthcare communication. Early detection significantly influences patient care by enabling timely interventions and suitable treatment strategies, particularly for low-stage BCs linked to reduced progression and recurrence rates.
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2834839-4
    ISSN 2514-8281
    ISSN 2514-8281
    DOI 10.5334/jbsr.3318
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  9. Article ; Online: Hepatic fascioliasis with metastasis appearance.

    Tasdemir, Merve Nur / Aslan, Serdar / Bekci, Tumay

    Revista da Sociedade Brasileira de Medicina Tropical

    2023  Volume 56, Page(s) e0117

    MeSH term(s) Humans ; Fascioliasis/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2023-06-02
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0117-2023
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  10. Article ; Online: A rare cause of acute abdominal pain: Perforation of a hepatic hydatid cyst into the peritoneum.

    Tonkaz, Gökhan / Akdeniz, Cemre / Tonkaz, Mehmet / Tonkaz, Duygu Erkal / Aslan, Serdar

    Cirugia espanola

    2024  

    Language English
    Publishing date 2024-04-09
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.cireng.2024.02.011
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