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  1. Article ; Online: Right heart failure due to arteriovenous fistula after spine surgery treated with endovascular repair.

    Park, Byoung-Won / Park, Young Woo / Nam, Bo Da / Kwon, Seong Soon

    Acta cardiologica

    2023  Volume 78, Issue 7, Page(s) 846–847

    MeSH term(s) Humans ; Arteriovenous Fistula/diagnosis ; Arteriovenous Fistula/etiology ; Arteriovenous Fistula/surgery ; Stents ; Endovascular Procedures/adverse effects ; Heart Failure/diagnosis ; Heart Failure/etiology
    Language English
    Publishing date 2023-05-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 390197-x
    ISSN 1784-973X ; 0001-5385
    ISSN (online) 1784-973X
    ISSN 0001-5385
    DOI 10.1080/00015385.2023.2209768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.50: Show issues Location:
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  2. Article: Erratum to "Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers" [Biomol Ther 28(4), 311-319 (2020)].

    Kandeel, Mahmoud / Yamamoto, Mizuki / Al-Taher, Abdulla / Watanabe, Aya / Oh-Hashi, Kentaro / Park, Byoung Kwon / Kwon, Hyung-Joo / Inoue, Jun-Ichiro / Al-Nazawi, Mohammed

    Biomolecules & therapeutics

    2024  Volume 32, Issue 2, Page(s) 262–265

    Language English
    Publishing date 2024-02-25
    Publishing country Korea (South)
    Document type Published Erratum
    ZDB-ID 2734146-X
    ISSN 2005-4483 ; 1976-9148
    ISSN (online) 2005-4483
    ISSN 1976-9148
    DOI 10.4062/biomolther.2024.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Molecular mapping of the broad bean wilt virus 2 resistance locus bwvr in Capsicum annuum using BSR-seq.

    Kim, Jung-Min / Lee, Joung-Ho / Park, Se-Ran / Kwon, Jin-Kyoung / Ro, Na-Young / Kang, Byoung-Cheorl

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

    2024  Volume 137, Issue 5, Page(s) 97

    Abstract: Key message: Bulked segregant RNA seq of pools of pepper accessions that are susceptible or resistant to Broad bean wilt virus 2 identifies a gene that might confer resistance to this devastating pathogen. The single-stranded positive-sense RNA virus ... ...

    Abstract Key message: Bulked segregant RNA seq of pools of pepper accessions that are susceptible or resistant to Broad bean wilt virus 2 identifies a gene that might confer resistance to this devastating pathogen. The single-stranded positive-sense RNA virus Broad bean wilt virus 2 (BBWV2) causes substantial damage to pepper (Capsicum annuum) cultivation. Here, we describe mapping the BBWV2 resistance locus bwvr using a F
    MeSH term(s) Chromosome Mapping ; RNA-Seq ; Capsicum/genetics ; Plant Breeding ; Polymorphism, Single Nucleotide ; Disease Resistance/genetics ; Plant Diseases/genetics ; Fabavirus
    Language English
    Publishing date 2024-04-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2170-2
    ISSN 1432-2242 ; 0040-5752
    ISSN (online) 1432-2242
    ISSN 0040-5752
    DOI 10.1007/s00122-024-04603-2
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1692: Show issues Location:
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  4. Article ; Online: Measurement of the thickness and refractive index of a thin film by analyzing reflected interference fringes.

    Kim, Deok Woo / Kwon, Minjae / Park, Soobong / Kim, Byoung Joo / Cha, Myoungsik

    Applied optics

    2023  Volume 62, Issue 30, Page(s) 8018–8024

    Abstract: We propose a novel, to the best of our knowledge, method to estimate the thickness and refractive index of a thin film by analyzing the reflectance as a function of the incidence angle. In most cases, interference fringes cannot be obtained from a film ... ...

    Abstract We propose a novel, to the best of our knowledge, method to estimate the thickness and refractive index of a thin film by analyzing the reflectance as a function of the incidence angle. In most cases, interference fringes cannot be obtained from a film within a practical angular range unless it is much thicker than the wavelength. This problem was solved by adopting a high-index material as the medium of incidence, in which case several cycles of interference fringes were observed within a small range of incidence angles near the critical angle, allowing a fringe analysis. Consequently, the thicknesses, as well as the refractive indices of dielectric thin films, could be estimated. Our proposed method gave uncertainties of 20 nm and 0.0004 for the thickness and refractive index measurements, respectively.
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.502870
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Correction: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study.

    Yang, Seo-Hee / Song, Myung Jin / Wook Kim, Yeon / Kwon, Byoung Soo / Lim, Sung Yoon / Lee, Yeon-Joo / Park, Jong Sun / Cho, Young-Jae / Lee, Jae Ho / Lee, Choon-Taek / Kim, Hyung-Jun

    BMC pulmonary medicine

    2024  Volume 24, Issue 1, Page(s) 81

    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-024-02881-6
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  6. Article ; Online: Association of glomerular hyperfiltration with carotid artery plaque in the general population.

    Kwon, Seong Soon / Lee, Haekyung / Park, Byoung-Won / Kwon, Soon Hyo / Bang, Duk Won / Jeon, Jin Seok / Noh, Hyunjin / Kim, Hyoungnae

    Atherosclerosis

    2023  Volume 369, Page(s) 30–36

    Abstract: Background and aims: Glomerular hyperfiltration (GHF) is a hemodynamic change of the kidney as an adaptive response to nephron loss. Although GHF is associated with metabolic risk factors and cardiovascular disease (CVD), the mechanisms that explain ... ...

    Abstract Background and aims: Glomerular hyperfiltration (GHF) is a hemodynamic change of the kidney as an adaptive response to nephron loss. Although GHF is associated with metabolic risk factors and cardiovascular disease (CVD), the mechanisms that explain these relationships remain largely unknown. This is partially caused by a non-unified definition of GHF based on pathophysiologic vascular changes. Thus, the objective of this study was to evaluate the association between various definitions of GHF and carotid plaque in a health checkup cohort.
    Methods: A total of 4493 individuals without history of CVD who had carotid ultrasonography (USG) results available between January 2016 and June 2018 were enrolled. GHF was defined as >90th percentile of eGFR residuals after adjusting for confounding factors. Carotid plaque score was calculated based on carotid USG results.
    Results: Of 4493 individuals (mean age, 52.3 ± 10.1 years; 3224 [71.8%] males), 449 subjects were included in the GHF group (mean eGFR, 107.0 ± 7.1 ml/min/1.73 m
    Conclusions: GHF status was associated with risk of carotid plaque in individuals without history of CVD. Presence of subclinical carotid plaque was associated with risk of future CVD. Therefore, GHF based on creatinine could be a useful surrogate marker for surveillance of CVD in asymptomatic individuals.
    MeSH term(s) Male ; Humans ; Adult ; Middle Aged ; Female ; Carotid Stenosis/complications ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/epidemiology ; Glomerular Filtration Rate/physiology ; Kidney Diseases/epidemiology ; Plaque, Atherosclerotic/epidemiology ; Risk Factors ; Cardiovascular Diseases/epidemiology
    Language English
    Publishing date 2023-01-24
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80061-2
    ISSN 1879-1484 ; 0021-9150
    ISSN (online) 1879-1484
    ISSN 0021-9150
    DOI 10.1016/j.atherosclerosis.2023.01.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 226: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: Giant coronary artery aneurysm in acute coronary syndrome.

    Kwon, Seong Soon / Park, Byoung-Won / Park, Young Woo

    Acta cardiologica

    2020  Volume 76, Issue 7, Page(s) 796–797

    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/etiology ; Coronary Aneurysm/diagnosis ; Coronary Aneurysm/etiology ; Coronary Angiography ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/surgery ; Humans ; No-Reflow Phenomenon ; Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction
    Language English
    Publishing date 2020-06-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 390197-x
    ISSN 1784-973X ; 0001-5385
    ISSN (online) 1784-973X
    ISSN 0001-5385
    DOI 10.1080/00015385.2020.1774182
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  8. Article: Suppression of Glioblastoma Stem Cell Potency and Tumor Growth via LRRK2 Inhibition.

    Park, Saewhan / Kim, Kyung-Hee / Bae, Yun-Hee / Oh, Young Taek / Shin, Hyemi / Kwon, Hyung Joon / Kim, Chan Il / Kim, Sung Soo / Choi, Hwan-Geun / Park, Jong Bae / Lee, Byoung Dae

    International journal of stem cells

    2024  

    Abstract: Leucine-rich repeat kinase 2 (LRRK2), a large GTP-regulated serine/threonine kinase, is well-known for its mutations causing late-onset Parkinson's disease. However, the role of LRRK2 in glioblastoma (GBM) carcinogenesis has not yet been fully elucidated. ...

    Abstract Leucine-rich repeat kinase 2 (LRRK2), a large GTP-regulated serine/threonine kinase, is well-known for its mutations causing late-onset Parkinson's disease. However, the role of LRRK2 in glioblastoma (GBM) carcinogenesis has not yet been fully elucidated. Here, we discovered that LRRK2 was overexpressed in 40% of GBM patients, according to tissue microarray analysis, and high LRRK2 expression correlated with poor prognosis in GBM patients. LRRK2 and stemness factors were highly expressed in various patient-derived GBM stem cells, which are responsible for GBM initiation. Canonical serum-induced differentiation decreased the expression of both LRRK2 and stemness factors. Given that LRRK2 is a key regulator of glioma stem cell (GSC) stemness, we developed DNK72, a novel LRRK2 kinase inhibitor that penetrates the blood-brain barrier. DNK72 binds to the phosphorylation sites of active LRRK2 and dramatically reduced cell proliferation and stemness factors expression in
    Language English
    Publishing date 2024-04-08
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2914134-5
    ISSN 2005-5447 ; 2005-3606
    ISSN (online) 2005-5447
    ISSN 2005-3606
    DOI 10.15283/ijsc24032
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  9. Article: BR101801 enhances the radiosensitivity of p53-deficient colorectal cancer cells by inducing G2/M arrest, apoptosis, and senescence in a p53-independent manner.

    Park, Mijeong / Ha, Jimin / Lee, Yuri / Kwon, Youngjoo / Choi, Sang Hyun / Kim, Byoung Soo / Jeong, Youn Kyoung

    American journal of cancer research

    2023  Volume 13, Issue 12, Page(s) 5887–5900

    Abstract: Inhibition of DNA-dependent protein kinase (DNA-PK) in the non-homologous end-joining repair pathway reportedly increases the radiation sensitivity of cancer cells. We have recently reported that BR101801, a novel triple inhibitor of PI3K-gamma (γ), ... ...

    Abstract Inhibition of DNA-dependent protein kinase (DNA-PK) in the non-homologous end-joining repair pathway reportedly increases the radiation sensitivity of cancer cells. We have recently reported that BR101801, a novel triple inhibitor of PI3K-gamma (γ), delta (δ), and DNA-PK, functions as an efficient sensitizer of radiation-induced DNA damage in various human solid cancer cells and a xenograft mouse model. Given that the p53 tumor suppressor gene plays an important role in radiotherapeutic efficacy, in the current study, we focused on the impact of the p53 status on BR101801-induced radiosensitization using isogenic HCT116 p53
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2589522-9
    ISSN 2156-6976
    ISSN 2156-6976
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  10. Article ; Online: Simultaneous Viability Assessment and Invasive Coronary Angiography Using a Therapeutic CT System in Chronic Myocardial Infarction Patients.

    Ha, Seongmin / Jang, Yeonggul / Lee, Byoung Kwon / Hong, Youngtaek / Kim, Byeong-Keuk / Park, Seil / Yoo, Sun Kook / Chang, Hyuk-Jae

    Yonsei medical journal

    2024  Volume 65, Issue 5, Page(s) 257–264

    Abstract: Purpose: In a preclinical study using a swine myocardial infarction (MI) model, a delayed enhancement (DE)-multi-detector computed tomography (MDCT) scan was performed using a hybrid system alongside diagnostic invasive coronary angiography (ICA) ... ...

    Abstract Purpose: In a preclinical study using a swine myocardial infarction (MI) model, a delayed enhancement (DE)-multi-detector computed tomography (MDCT) scan was performed using a hybrid system alongside diagnostic invasive coronary angiography (ICA) without the additional use of a contrast agent, and demonstrated an excellent correlation in the infarct area compared with histopathologic specimens. In the present investigation, we evaluated the feasibility and diagnostic accuracy of a myocardial viability assessment by DE-MDCT using a hybrid system comprising ICA and MDCT alongside diagnostic ICA without the additional use of a contrast agent.
    Materials and methods: We prospectively enrolled 13 patients (median age: 67 years) with a previous MI (>6 months) scheduled to undergo ICA. All patients underwent cardiac magnetic resonance (CMR) imaging before diagnostic ICA. MDCT viability scans were performed concurrently with diagnostic ICA without the use of additional contrast. The total myocardial scar volume per patient and average transmurality per myocardial segment measured by DE-MDCT were compared with those from DE-CMR.
    Results: The DE volume measured by MDCT showed an excellent correlation with the volume measured by CMR (r=0.986,
    Conclusion: The feasibility of the DE-MDCT viability assessment acquired simultaneously with conventional ICA was proven in patients with chronic MI using DE-CMR as the reference standard.
    MeSH term(s) Humans ; Myocardial Infarction/diagnostic imaging ; Myocardial Infarction/pathology ; Aged ; Coronary Angiography/methods ; Male ; Female ; Middle Aged ; Prospective Studies ; Magnetic Resonance Imaging/methods ; Tomography, X-Ray Computed/methods ; Multidetector Computed Tomography/methods
    Language English
    Publishing date 2024-04-21
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 303740-x
    ISSN 1976-2437 ; 0513-5796
    ISSN (online) 1976-2437
    ISSN 0513-5796
    DOI 10.3349/ymj.2023.0208
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    Zs.B 944: Show issues Location:
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