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  1. Article ; Online: Pathways of Water-Induced Lead-Halide Perovskite Surface Degradation: Insights from

    Il Jake Choi, Joong / Ono, Luis K / Cho, Hunyoung / Kim, Ki-Jeong / Kang, Hyung-Been / Qi, Yabing / Park, Jeong Young

    ACS nano

    2023  Volume 17, Issue 24, Page(s) 25679–25688

    Abstract: While organic-inorganic hybrid perovskites are emerging as promising materials for next-generation photovoltaic applications, the origins and pathways of perovskite instability remain speculative. In particular, the degradation of perovskite surfaces by ... ...

    Abstract While organic-inorganic hybrid perovskites are emerging as promising materials for next-generation photovoltaic applications, the origins and pathways of perovskite instability remain speculative. In particular, the degradation of perovskite surfaces by ambient water is a crucial subject for determining the long-term viability of perovskite-based solar cells. Here, we conducted surface characterization and atomic-scale analysis of the reaction mechanisms for methylammonium lead bromide (MA(CH
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.3c10611
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ventricular fibrillation associated with Graves' disease and amiodarone induced thyrotoxicosis.

    Cho, Jake / Afolabi, Bosede

    Cardiovascular endocrinology & metabolism

    2019  Volume 8, Issue 4, Page(s) 119–124

    Abstract: This case involves a 55-year-old male patient with systolic heart failure and refractory atrial fibrillation due to thyrotoxicosis, who was electrically cardioverted but then developed torsade de pointes and ventricular fibrillation. Rate control was ... ...

    Abstract This case involves a 55-year-old male patient with systolic heart failure and refractory atrial fibrillation due to thyrotoxicosis, who was electrically cardioverted but then developed torsade de pointes and ventricular fibrillation. Rate control was unsuccessful with digoxin, cardizem, labetalol, esmolol and amiodorone. Patient was externally cardioverted after which ECGs showed prolonged QT with frequent premature ventricular contractions. ECGs also showed 'R-on-T' phenomenon leading to torsades and ventricular fibrillation. Atrial overdrive pacing was used to terminate the dangerous arrhythmia and the patient returned to sinus rhythm. Interestingly, he was found to have new onset thyrotoxicosis and started on methimazole.
    Language English
    Publishing date 2019-11-13
    Publishing country United States
    Document type Case Reports
    ISSN 2574-0954
    ISSN (online) 2574-0954
    DOI 10.1097/XCE.0000000000000184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Case report: left atrial Myxoma causing elevated C-reactive protein, fatigue and fever, with literature review.

    Cho, Jake / Quach, Steven / Reed, Justin / Osian, Omeni

    BMC cardiovascular disorders

    2020  Volume 20, Issue 1, Page(s) 119

    Abstract: Background: A cardiac myxoma in a young person may pose a diagnostic challenge as symptoms may be variable and the differential diagnosis is wide. The differential diagnosis can include rheumatic mitral valve disease, pulmonary hypertension, ... ...

    Abstract Background: A cardiac myxoma in a young person may pose a diagnostic challenge as symptoms may be variable and the differential diagnosis is wide. The differential diagnosis can include rheumatic mitral valve disease, pulmonary hypertension, endocarditis, myocarditis and vasculitis.
    Case presentation: This case report involves a 49 years old female with a 2.8 cm × 3.4 cm myxoma in the left atrium causing mitral valve obstruction. She presented with fatigue, fever of unknown origin, transient ischemic attack and shortness of breath. Prompt surgery is often recommended due to the risk of embolic complications or complete obstruction. Due to her symptoms, patient underwent successful cardiothoracic surgery to excise the myxoma within 2 weeks of confirmation by cardiac echocardiography.
    Conclusion: This case also emphasizes the diagnostic challenge as symptoms may be variable, ranging from fatigue, fever and shortness of breath to transient ischemic attack and at worst, sudden cardiac death. In conclusion, if a cardiac mass is suspected, echocardiography should be performed early. Surgical resection is curative and recurrence rate is very rare in sporadic isolated myxomas, however, recurrence can be higher in genetic diseases associated with increased frequency of myxomas such as Carney complex. This subpopulation of patients may present further research opportunity to learn more about the perioperative management of patients with myxomas such as determining the optimal time to surgical intervention and decision to anticoagulate.
    MeSH term(s) Biomarkers/blood ; C-Reactive Protein/analysis ; Diagnosis, Differential ; Fatigue/diagnosis ; Fatigue/etiology ; Female ; Fever of Unknown Origin/etiology ; Heart Atria ; Heart Neoplasms/complications ; Heart Neoplasms/diagnostic imaging ; Heart Neoplasms/surgery ; Humans ; Middle Aged ; Myxoma/complications ; Myxoma/diagnostic imaging ; Myxoma/surgery ; Predictive Value of Tests ; Treatment Outcome
    Chemical Substances Biomarkers ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2020-03-05
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-020-01397-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Pancytopenia as a Consequence of Sepsis and Intravenous Antibiotic Drug Toxicity.

    Cho, Jake N / Avera, Stephen / Iyamu, Kenneth

    Cureus

    2019  Volume 11, Issue 2, Page(s) e3994

    Abstract: This case involves a 62-year-old male with a prior history of epidural abscess and L1-L2 osteodiscitis who was admitted because of low back pain. The patient was previously treated for methicillin-susceptible Staphylococcus aureus (MSSA) discitis in the ... ...

    Abstract This case involves a 62-year-old male with a prior history of epidural abscess and L1-L2 osteodiscitis who was admitted because of low back pain. The patient was previously treated for methicillin-susceptible Staphylococcus aureus (MSSA) discitis in the L1/L2 vertebral region with intravenous (IV) nafcillin through a peripherally inserted central catheter (PICC). However, he returned after four months with recurrent low back pain along with chills and fever. He was admitted for severe sepsis related to the L1-L2 region osteomyelitis and discitis. The Infectious Disease department initially started the patient on IV vancomycin and cefepime; however, routine labs on the second day of IV antibiotics showed concern for pancytopenia with white blood cell count (WBC) decreased to 2.5 thou/mm
    Language English
    Publishing date 2019-02-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.3994
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Spectrin-beta 2 facilitates the selective accumulation of GABA

    Smalley, Joshua L / Cho, Noell / Ng, Shu Fun Josephine / Choi, Catherine / Lemons, Abigail H S / Chaudry, Saad / Bope, Christopher E / Dengler, Jake S / Zhang, Chuansheng / Rasband, Matthew N / Davies, Paul A / Moss, Stephen J

    Communications biology

    2023  Volume 6, Issue 1, Page(s) 11

    Abstract: Fast synaptic inhibition is dependent on targeting specific ... ...

    Abstract Fast synaptic inhibition is dependent on targeting specific GABA
    MeSH term(s) Receptors, GABA-A/metabolism ; Spectrin/metabolism ; Synapses/metabolism ; Membrane Proteins/metabolism ; gamma-Aminobutyric Acid/metabolism
    Chemical Substances Receptors, GABA-A ; Spectrin (12634-43-4) ; Membrane Proteins ; gamma-Aminobutyric Acid (56-12-2)
    Language English
    Publishing date 2023-01-05
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-022-04381-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A rare case of focal segmental glomerular sclerosis and subsequent necrotizing crescentic glomerulonephritis in the same patient

    Jake Cho / Erika Lara / Izuchukwu Nwakoby

    Journal of Nephropathology, Vol 8, Iss 3, Pp e28-e

    2019  Volume 28

    Abstract: Background: Focal segmental glomerular sclerosis (FSGS) and necrotizing crescentic glomerulonephritis is a rare combination of diagnoses in the same patient. We report on a patient with FSGS who 10 years later developed anti-neutrophil cytoplasmic ... ...

    Abstract Background: Focal segmental glomerular sclerosis (FSGS) and necrotizing crescentic glomerulonephritis is a rare combination of diagnoses in the same patient. We report on a patient with FSGS who 10 years later developed anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis. Case Presentation: Patient is a 60-year-old female with chronic kidney disease stage 3, osteopenia and anemia. In 2007, she was positive for ANCA proteinase-3 antibody, but kidney biopsy revealed FSGS. She was treated with high-dose oral steroids with tapered dose and went into remission. In 2017, she developed acute renal failure with increased proteinuria. Despite prior FSGS diagnosis, her new kidney biopsy revealed pauci-immune necrotizing glomerulonephritis. Patient was treated with methylprednisolone 250 mg IV for three days and high dose oral steroids with tapered dose. She was also started on rituximab 375 mg/m2 IV once weekly for 4 doses. Given the extent of kidney damage, the patient decided to start peritoneal dialysis and she is also on the kidney transplant list. Conclusions: The rare concurrence of FSGS and ANCA associated glomerulonephritis has not yet been reported. The case also emphasizes the significance of screening for ANCA or obtaining kidney biopsy when indicated not only as the gold standard for diagnosis but also as prognostic value.
    Keywords chronic kidney disease ; end stage renal disease ; rapidly progressive glomerulonephritis ; pauci-immune crescentic glomerulonephritisclerosis ; focal segmental glomerular sclerosis ; gloerulonephritis ; Pathology ; RB1-214 ; Internal medicine ; RC31-1245 ; Other systems of medicine ; RZ201-999
    Subject code 616
    Language English
    Publishing date 2019-07-01T00:00:00Z
    Publisher Society of Diabetic Nephropathy Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Optic nerve sheath diameter correlates to intracranial pressure in spontaneous CSF leak patients.

    Tilak, Ashwini M / Yang, Lydia C / Morgan, Jake / Peña-Garcia, Jaime / Thompson, Maxwell / Burleson, Samuel / Atkins, Amanda / Sheehan, Delaney / Cho, Do-Yeon / Woodworth, Bradford A / Grayson, Jessica W

    International forum of allergy & rhinology

    2023  Volume 13, Issue 8, Page(s) 1518–1524

    Abstract: Background: Spontaneous cerebrospinal fluid (sCSF) leaks develop from pressure erosion due to idiopathic intracranial hypertension, treatment of which is paramount to preventing recurrence. Direct measurements of intracranial pressure (ICP) for ... ...

    Abstract Background: Spontaneous cerebrospinal fluid (sCSF) leaks develop from pressure erosion due to idiopathic intracranial hypertension, treatment of which is paramount to preventing recurrence. Direct measurements of intracranial pressure (ICP) for monitoring response to treatment via lumbar drain (LD) or ventriculostomy are invasive and have risks. The objectives of this study are to determine whether ultrasonographic measurements of optic nerve sheath diameter (ONSD) correlate with LD ICP in patients with sCSF leaks undergoing treatment, and whether ONSDs are larger in patients with sCSF leaks than controls.
    Methods: Subjects with sCSF leaks and controls were prospectively recruited. ONSD, sex, and body mass index (BMI) were analyzed. For sCSF leak subjects, ultrasonography was performed at the time of LD opening and each pressure check postoperatively, including the acetazolamide response. In control patients, measurements were obtained at the time of surgery. Pearson's correlation between ONSD and ICP was performed.
    Results: Subjects with sCSF leaks (n = 9, age 52.4 ± 9.5, all female) and controls (n = 8, age 60.1 ± 14.8, two females) had significantly different BMIs, 38.4 ± 8.1 vs. 29.2 ± 4.8, t(15) = 2.793, p = 0.014. ONSD was strongly correlated with ICP measurements (r = 0.583, p = 0.002). However, percentage change in ONSD and ICP measurements were more strongly correlated (r = 0.733, p < 0.001). Patients with sCSF leaks had significantly higher ONSDs than controls, 0.63 cm ± 0.044 vs. 0.56 cm ± 0.074, t(15) = 2.329, p = 0.034.
    Conclusion: ONSD significantly correlated with ICP in sCSF leak patients and was wider in sCSF leak subjects than controls. Ultrasonography has utility in monitoring the ICP response to acetazolamide.
    MeSH term(s) Humans ; Female ; Adult ; Middle Aged ; Aged ; Intracranial Pressure/physiology ; Optic Nerve/diagnostic imaging ; Intracranial Hypertension/diagnostic imaging ; Acetazolamide/therapeutic use ; Pseudotumor Cerebri/diagnostic imaging ; Ultrasonography
    Chemical Substances Acetazolamide (O3FX965V0I)
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2625826-2
    ISSN 2042-6984 ; 2042-6976
    ISSN (online) 2042-6984
    ISSN 2042-6976
    DOI 10.1002/alr.23120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Synthesis of Deuterated and Sulfurated Polymers by Inverse Vulcanization: Engineering Infrared Transparency via Deuteration.

    Qureshi, Munaum H / Bao, Jianhua / Kleine, Tristan S / Kim, Kyung-Jo / Carothers, Kyle J / Molineux, Jake / Cho, Eunkyung / Kang, Kyung-Seok / Godman, Nicholas P / Coropceanu, Veaceslav / Bredas, Jean-Luc / Norwood, Robert A / Njardarson, Jon T / Pyun, Jeffrey

    Journal of the American Chemical Society

    2023  Volume 145, Issue 50, Page(s) 27821–27829

    Abstract: The synthesis of deuterated, sulfurated, proton-free, glassy polymers offers a route to optical polymers for infrared (IR) optics, specifically for midwave IR (MWIR) photonic devices. Deuterated polymers have been utilized to enhance neutron cross- ... ...

    Abstract The synthesis of deuterated, sulfurated, proton-free, glassy polymers offers a route to optical polymers for infrared (IR) optics, specifically for midwave IR (MWIR) photonic devices. Deuterated polymers have been utilized to enhance neutron cross-sectional contrast with
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c10985
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diffuse Exfoliative Rash with Sepsis and Eosinophilia: A Case of Erythroderma?

    Cho, Jake / Elyaman, Selsabeel A / Avera, Stephen A / Iyamu, Kenneth

    The American journal of case reports

    2019  Volume 20, Page(s) 1387–1393

    Abstract: ... BACKGROUND ... Erythroderma is an exfoliative dermatitis that manifests as generalized erythema and scaling that involves 90% of the body surface. If untreated, erythroderma can be fatal because of its metabolic burden and risk of secondary ... ...

    Abstract BACKGROUND Erythroderma is an exfoliative dermatitis that manifests as generalized erythema and scaling that involves 90% of the body surface. If untreated, erythroderma can be fatal because of its metabolic burden and risk of secondary infections. CASE REPORT The patient was a 56-year-old male with prior rash attributed to group A Streptococcal cellulitis and discharged on Augmentin, Clindamycin with hydrocortisone cream, and Bactrim, but he had been noncompliant. He was admitted again for rash involving the face, torso, and extremities characterized by diffuse, desquamative, dry scales in morbilliform pattern. The patient was septic with Staphylococcus aureus bacteremia and compromised skin barrier. He was started on vancomycin and switched to Cefazolin IV due to concern for drug reaction. Autoimmune workup included antibodies for anti-Jo-1, anti-dsDNA, anti-centromere, and ANCA. However, only antinuclear antibody and scleroderma antibody were positive. Given the unclear workup results and lack of response to antibiotics, the patient was started on prednisone 60 mg PO and topical Triamcinolone 0.1% cream. A skin biopsy revealed psoriasiform hyperplasia with atypical T cell infiltrate and eosinophils, but negative for T cell gene rearrangement. The rash resolved after day 12 of application of topical Triamcinolone. CONCLUSIONS This case is unique in terms of the rarity of erythroderma and the diagnostic challenge given confounding factors such as noncompliance and drug reaction. Serious causes, such as SLE and cutaneous T cell lymphoma, were ruled out. Fortunately, the rash responded well to steroids; however, given the adverse effects of long-term use of topical steroids, the patient will need follow up with Dermatology.
    MeSH term(s) Administration, Topical ; Cellulitis/microbiology ; Dermatitis, Exfoliative/diagnosis ; Dermatitis, Exfoliative/drug therapy ; Eosinophilia/etiology ; Glucocorticoids/therapeutic use ; Humans ; Male ; Medication Adherence ; Middle Aged ; Sepsis/microbiology ; Staphylococcal Infections/complications ; Streptococcal Infections/complications ; Streptococcus pyogenes ; Triamcinolone/therapeutic use
    Chemical Substances Glucocorticoids ; Triamcinolone (1ZK20VI6TY)
    Language English
    Publishing date 2019-09-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.917427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Risk factors for postoperative wound dehiscence after skin repair: A case-control study.

    Alam, Murad / Harikumar, Vishnu / Reynolds, Kelly A / Hsu, Derek Y / Lazaroff, Jake M / Chen, Brian R / Jain-Poster, Ketan / Gwillim, Eran C / Ibrahim, Sarah / Kang, Bianca Y / Cho, Nancy L / Leitao, Mario M / Kim, John Y / Christensen, Rachel E / Poon, Emily / Nardone, Beatrice

    Journal of the American Academy of Dermatology

    2022  Volume 87, Issue 5, Page(s) 1099–1102

    MeSH term(s) Case-Control Studies ; Humans ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Risk Factors ; Skin Transplantation/adverse effects ; Surgical Wound Dehiscence/epidemiology ; Surgical Wound Dehiscence/etiology
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2022.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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