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  1. Book ; Online ; E-Book: Retinal dystrophy gene atlas

    Zahid, Sarwar / Branham, Kari / Schlegel, Dana / Pennesi, Mark E. / Michaelides, Michel / Heckenlively, John R. / Jayasundera, Thiran

    2018  

    Author's details Sarwar Zahid, Kari Branham, Dana Schlegel, Mark E. Pennesi, Michel Michaelides, John Heckenlively, Thiran Jayasundera
    Keywords Medicine ; Ophthalmology
    Subject code 617.7
    Language English
    Size 1 Online-Ressource (xiii, 279 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019761640
    ISBN 978-3-319-10867-4 ; 9783319108667 ; 3-319-10867-0 ; 3319108662
    DOI 10.1007/978-3-319-10867-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Eco-friendly approaches of zinc oxide and silver nitrate nanoparticles along with plant extracts against

    Shabir, Aqsa / Sarwar, Zahid Mahmood / Ali, Habib

    Science progress

    2023  Volume 106, Issue 4, Page(s) 368504231219171

    Abstract: The tobacco cutworm ( ...

    Abstract The tobacco cutworm (
    MeSH term(s) Animals ; Ecosystem ; Ethanol ; Larva ; Metal Nanoparticles/toxicity ; Nitrates/pharmacology ; Plant Extracts/pharmacology ; Silver/pharmacology ; Silver Nitrate/pharmacology ; Spodoptera ; Zinc Oxide/pharmacology ; Pest Control
    Chemical Substances Ethanol (3K9958V90M) ; Nitrates ; Plant Extracts ; Silver (3M4G523W1G) ; Silver Nitrate (95IT3W8JZE) ; Zinc Oxide (SOI2LOH54Z)
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504231219171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 731: Show issues Location:
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  3. Article ; Online: How do firms create business value and dynamic capabilities by leveraging big data analytics management capability?

    Gao, Jingmei / Sarwar, Zahid

    Information technology & management

    2022  , Page(s) 1–22

    Abstract: Despite researchers having averred that big data analytics (BDA) transforms firms' ways of doing business, knowledge about operationalizing these technologies in organizations to achieve strategic objectives is lacking. Moreover, organizations' great ... ...

    Abstract Despite researchers having averred that big data analytics (BDA) transforms firms' ways of doing business, knowledge about operationalizing these technologies in organizations to achieve strategic objectives is lacking. Moreover, organizations' great appetite for big data and limited empirical proof of whether BDA impacts organizations' transformational capacity poses a need for further empirical investigation. Therefore, this study explores the association between big data analytics management capabilities (BDAMC) and innovation performance via dynamic capabilities (DC), by applying the PLS-SEM technique to analyzing the feedback of 149 firms. Consequently, we ground our arguments on dynamic capability and social capital theory rather than a resource-based view that does not provide suitable explanations for the deployment of resources to adapt to change. Accordingly, we advance this research stream by finding that BDAMC significantly enhances innovation performance through DC. We also extend the literature by disclosing how BDAMC strengthens DC via strategic alignment and social capital.
    Language English
    Publishing date 2022-10-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2035174-4
    ISSN 1573-7667 ; 1385-951X
    ISSN (online) 1573-7667
    ISSN 1385-951X
    DOI 10.1007/s10799-022-00380-w
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  4. Article: Psychosocial issues of hearing impaired school children: a psychometric approach.

    Saleem, Sadia / Sarwar, Anila / Mahmood, Zahid

    JPMA. The Journal of the Pakistan Medical Association

    2022  Volume 71, Issue 1(B), Page(s) 306–309

    Abstract: Objective: To develop a valid and reliable scale for measuring psychosocial issues of hearing-impaired school children.: Methods: The cross-sectional study with four stage model of scale development was conducted at Multan, Muzafargarh, and Dera ... ...

    Abstract Objective: To develop a valid and reliable scale for measuring psychosocial issues of hearing-impaired school children.
    Methods: The cross-sectional study with four stage model of scale development was conducted at Multan, Muzafargarh, and Dera Ghazi Khan Pakistan from August 2018 to January 2019. The four stages were item generation, expert validation, conversion of scale into sign language and psychometric study. The sample comprised hearing-impaired school children aged 18-23 years who were studying Special Education schools in Multan, Pakistan.
    Results: Of the 230 subjects, there were 110(47.8%) boys and 120(52.2%) girls. The overall mean age was 19.90±2.46 years. Exploratory factor analysis with varimax rotation revealed 26 items in 'Depressive Affect', 'Social Isolation' and 'Feeling of Anger' sub-scales with high internal consistency (r=0.85) and validity (r=-0.32).
    Conclusions: The internalised nature of psychosocial issues of children with hearing impairment needs timely identification and intervention so that silent suffering can be prevented to improve psychosocial functioning of such children.
    MeSH term(s) Adolescent ; Adult ; Child ; Cross-Sectional Studies ; Factor Analysis, Statistical ; Female ; Hearing ; Humans ; Male ; Psychometrics ; Reproducibility of Results ; Schools ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2022-01-31
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.812
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 845: Show issues Location:
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  5. Article: Is complete pathological response truly a complete response in breast cancer?

    Rehman, Bushra / Rehman, Sara / Mohtasham, Sameen / Zahid, Toqeer / Sarwar, Albash / Parvaiz, Muhammad Asad

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 73, Issue 2, Page(s) 280–283

    Abstract: Objective: To check if complete pathological response in breast cancer is a good prognostic factor.: Methods: The retrospective study was conducted at the Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised ... ...

    Abstract Objective: To check if complete pathological response in breast cancer is a good prognostic factor.
    Methods: The retrospective study was conducted at the Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised data from January 2012 to December 2015 of all patients who received neo-adjuvant chemotherapy and had no distant metastasis at diagnosis. Mastectomy patients were excluded. Complete pathological response was defined as no detectable tumour cell in breast and axilla on pathological examination of the resected specimen. Tumour characteristics and 5-year disease free survival and overall survival were recorded. Data was analysed using SPSS 20.
    Results: Of the 353 patients whose data was evaluated, 91(25.8%) had complete pathological response. Mean age at diagnosis was 43±10 years. Among them, 62(68%) patients had grade III tumour, 39(42.9%) were negative for oestrogen receptor, 58(63.7%) were negative for progesterone receptor, 25(27.5%) were positive for human epidermal growth factor receptor 2, and 26(28.6%) patients were triple negative. Overall, 28((30.7%) patients had recurrence; 20(71.4%) had distant metastasis, 6(21.4%) had local recurrence, and 2(7.14%) had contralateral cancer. The 5-year disease-free survival and overall survival rates (Kaplan-Meier Survial curve) were 70% (28 patients-recurrence) and 87% (15 patients-deaths), respectively.
    Conclusion: Despite complete disappearance of tumour, a significant number of patients developed recurrences.
    MeSH term(s) Humans ; Adult ; Middle Aged ; Female ; Breast Neoplasms/therapy ; Retrospective Studies ; Mastectomy ; Breast ; Disease-Free Survival
    Language English
    Publishing date 2023-02-17
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.5574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Negative Impact of Unstable Spiromesifen Resistance on Fitness of Tetranychus urticae (Acari: Tetranychidae).

    Abubakar, Muhammad / Umer, Ayyan / Shad, Sarfraz Ali / Sarwar, Zahid Mehmood / Kamran, Muhammad

    Neotropical entomology

    2023  Volume 52, Issue 4, Page(s) 772–780

    Abstract: Two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae), is a phytophagous haplodiploid mite and its control is largely based on the use of pesticides. But, the short life cycle and high reproductive rate allow them to develop resistance ...

    Abstract Two-spotted spider mite, Tetranychus urticae Koch (Acari: Tetranychidae), is a phytophagous haplodiploid mite and its control is largely based on the use of pesticides. But, the short life cycle and high reproductive rate allow them to develop resistance to many pesticides. To design a strategy for resistance management, a fitness cost study was conducted on different populations of T. urticae, i.e., spiromesifen selected (SPIRO-SEL), unselected (Unsel), and reciprocal crosses. After twelve rounds of selections, T. urticae developed high spiromesifen resistance (71.7-fold) compared to the Unsel strain. Results showed a fitness cost for SPIRO-SEL, Cross
    MeSH term(s) Female ; Male ; Animals ; Acaricides ; Tetranychidae ; Spiro Compounds ; Pesticides
    Chemical Substances Acaricides ; spiromesifen (N726NTQ5ZC) ; Spiro Compounds ; Pesticides
    Language English
    Publishing date 2023-05-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2105363-7
    ISSN 1678-8052 ; 1519-566X
    ISSN (online) 1678-8052
    ISSN 1519-566X
    DOI 10.1007/s13744-023-01050-4
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  7. Article ; Online: Immunoinformatics approach to design next-generation epitope-based peptide vaccine against Peste des Petits Ruminants Virus (PPRV)

    Riaz, Rimsha / Zahid, Saira / Khan, Muhammad Sarwar

    Process Biochemistry. 2023 Apr. 11,

    2023  

    Abstract: PPR is a small ruminant infectious illness that is wreaking havoc on economies in South Asia and Africa. Due to several hurdles, such as resistant strains and a limited regulatory framework, existing therapeutic vaccinations have failed to eradicate the ... ...

    Abstract PPR is a small ruminant infectious illness that is wreaking havoc on economies in South Asia and Africa. Due to several hurdles, such as resistant strains and a limited regulatory framework, existing therapeutic vaccinations have failed to eradicate the disease. To overcome these challenges, a peptide-based vaccination with distinct immunological characteristics and less vulnerability to contamination, autoimmunity, and inflammatory diseases would be useful in accomplishing the suggested eradication goal. The possible CTL and B-cell epitopes of PPRV's four immunogenic proteins (H, F, M, and N) were predicted using a variety of immunoinformatic methods. Protein-protein docking confirmed that the proposed chimeric vaccine has a considerable affinity for the ovine toll-like receptor. In a biological system, the molecular dynamic simulation confirmed the in vivo stability of the protein. The immune simulation predicted the induction of immunoglobulins, interleukins, interferons, helper T cells, and cytotoxic T cells, which is critical for boosting host immunity during infection. Moreover, the translation efficiency was verified through in silico cloning of the vaccine in a bacterial expression system following codon optimization. Thus, our findings suggest that the candidate vaccine will help in provoking a robust and long-lasting immunity in animals against PPRV infection.
    Keywords B-lymphocytes ; Toll-like receptors ; autoimmunity ; computer simulation ; cytotoxicity ; epitopes ; immunoglobulins ; immunoinformatics ; interleukins ; recombinant vaccines ; sheep ; vaccination ; Africa ; South Asia ; CTL epitopes ; B-cell epitopes ; Multi-Epitope Vaccine (MEV) ; Molecular docking ; Immune simulation
    Language English
    Dates of publication 2023-0411
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ISSN 1359-5113
    DOI 10.1016/j.procbio.2023.04.009
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Mortality effects of hypercapnia in modified atmospheres on larval and adult stages of red flour beetle Tribolium castaneum (Herbst)

    Sarwar, Zahid Mahmood / Fatima, Nishat / Sajjād, Muḥammad

    International journal of tropical insect science. 2021 Mar., v. 41, no. 1 p.587-592

    2021  

    Abstract: Insect pests not only damaged field crops during the growing season, but also injured stored grain and stored food commodities. The development of substitute treatments for pest control in food products is an increasing demand from the food industry, ... ...

    Abstract Insect pests not only damaged field crops during the growing season, but also injured stored grain and stored food commodities. The development of substitute treatments for pest control in food products is an increasing demand from the food industry, which should meet consumer demands for the minimum use or elimination of pesticides. Modified atmospheres with higher concentrations of atmospheric gases, especially carbon dioxide (CO₂) provide a cost-effective method to kill pests of stored products. CO₂ is one of the hastiest option for arthropods control among latest commercial treatments, proposing complete control within hours. In present study aimed to determine the efficacy of CO₂ against different stages of Tribolium castaneum (Herbst) that affect stored-food products. Different levels of the carbon dioxide like 25, 30, 35, 40 and 45% were used to protect the different flours such as chickpea, wheat, peanuts, porridge, rice and maize from the larvae and adult of red flour beetle under laboratory conditions at 27 ± 2 °C with Light (L): Dark (D) 12: 12, and 65 ± 5% relative humidity. Results showed that mortality increased with the increase of concentration CO2 level.
    Keywords Tribolium castaneum ; carbon dioxide ; chickpeas ; corn ; cost effectiveness ; food industry ; hypercapnia ; larvae ; mortality ; pest control ; porridge ; relative humidity ; rice ; stored grain ; wheat
    Language English
    Dates of publication 2021-03
    Size p. 587-592.
    Publishing place Springer International Publishing
    Document type Article ; Online
    Note NAL-light
    ZDB-ID 2166668-4
    ISSN 1742-7592 ; 1742-7584
    ISSN (online) 1742-7592
    ISSN 1742-7584
    DOI 10.1007/s42690-020-00243-3
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4487: Show issues

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  9. Article ; Online: Antibiotyping and genotyping of extensively drug-resistant (XDR) Salmonella sp. isolated from clinical samples of Lahore, Pakistan.

    Zahid, Iqra / Sarwar, Arslan / Hussain, Abid / Sohail, Muhammad / Amin, Aatif

    Journal of applied microbiology

    2021  Volume 132, Issue 1, Page(s) 633–641

    Abstract: Aims: Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi. The objective of this study was to evaluate the prevalence of XDR Salmonella among local population of Lahore and genotyping of isolates for antibiotic-resistant genes.! ...

    Abstract Aims: Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi. The objective of this study was to evaluate the prevalence of XDR Salmonella among local population of Lahore and genotyping of isolates for antibiotic-resistant genes.
    Methods and results: A total of 200 blood samples from suspected typhoid fever patients were collected. One hundred and fifty-seven bacterial samples were confirmed as Salmonella Typhi and 23 samples were confirmed as Salmonella Paratyphi after biochemical, serological and PCR based molecular characterization. Antibiogram analysis classified 121 (67·2%) Salmonella isolates as MDR and 62 isolates (34·4%) as XDR. The predominant resistance gene was ampC with 47·7% prevalence, followed by gyrA, catA1, tet(A), aac (3)-la, qnrS, bla
    Conclusion: Large number of clinical XDR S. Typhi-resistant against third generation cephalosporins have been reported.
    Significance and impact of the study: The current study highlights the possible emergence of clinical XDR S. Typhi cases in Lahore, Pakistan. Potential attribution of phenotypic and genotypic XDR cases may help to contribute targeted therapy.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Genotype ; Humans ; Microbial Sensitivity Tests ; Pakistan ; Pharmaceutical Preparations ; Salmonella typhi/genetics ; Typhoid Fever
    Chemical Substances Anti-Bacterial Agents ; Pharmaceutical Preparations
    Language English
    Publishing date 2021-07-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1358023-1
    ISSN 1365-2672 ; 1364-5072
    ISSN (online) 1365-2672
    ISSN 1364-5072
    DOI 10.1111/jam.15131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 259: Show issues Location:
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  10. Article ; Online: Toward explainable AI-empowered cognitive health assessment.

    Javed, Abdul Rehman / Khan, Habib Ullah / Alomari, Mohammad Kamel Bader / Sarwar, Muhammad Usman / Asim, Muhammad / Almadhor, Ahmad S / Khan, Muhammad Zahid

    Frontiers in public health

    2023  Volume 11, Page(s) 1024195

    Abstract: Explainable artificial intelligence (XAI) is of paramount importance to various domains, including healthcare, fitness, skill assessment, and personal assistants, to understand and explain the decision-making process of the artificial intelligence (AI) ... ...

    Abstract Explainable artificial intelligence (XAI) is of paramount importance to various domains, including healthcare, fitness, skill assessment, and personal assistants, to understand and explain the decision-making process of the artificial intelligence (AI) model. Smart homes embedded with smart devices and sensors enabled many context-aware applications to recognize physical activities. This study presents
    MeSH term(s) Humans ; Artificial Intelligence ; Bayes Theorem ; Neural Networks, Computer ; Awareness ; Dementia
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1024195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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