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Article ; Online: mHealth in psychiatry: A pathway to person-centered care.

Myin-Germeys, Inez

2022 Volume 319, Page(s) 114978

Abstract: Influenced by the field of epidemiology and the early ecological psychologists, my research focused on the role of person-environment interactions in the development and maintenance of psychopathology - a field I would name Contextual Psychiatry. To ... ...

Abstract	Influenced by the field of epidemiology and the early ecological psychologists, my research focused on the role of person-environment interactions in the development and maintenance of psychopathology - a field I would name Contextual Psychiatry. To capture the interaction between the person and the environment, I was one of the early adopters of the Experience Sampling Method (ESM) in mental health research. Using ESM, we demonstrated that there is an affective pathway to psychosis, characterized by increased stress-reactivity. Also altered social interactions have been identified as an important factor in the development of psychopathology. With digital technology quickly evolving, the impact of my work has now been extended to the development and implementation of mHealth and digital Health approaches in mental health, including the clinical application of ESM in routine mental health care as well as the development of Ecological Momentary Interventions. Moving forward, if we want to deliver treatment at moments when it is most needed and adapted to the needs of the individual, we need to advance our understanding of the real-time dynamics of the psychological and physiological processes of psychopathology - thus establishing a more personalised mental health care.
MeSH term(s)	Humans ; Psychotic Disorders/psychology ; Mental Health ; Psychiatry ; Telemedicine ; Patient-Centered Care
Language	English
Publishing date	2022-11-21
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2022.114978
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Article ; Online: Digital technology in psychiatry: towards the implementation of a true person-centered care in psychiatry?

Myin-Germeys, Inez

European archives of psychiatry and clinical neuroscience

2020 Volume 270, Issue 4, Page(s) 401–402

MeSH term(s)	Digital Technology ; Humans ; Patient-Centered Care ; Psychiatry/methods ; Psychiatry/standards
Keywords	covid19
Language	English
Publishing date	2020-05-03
Publishing country	Germany
Document type	Editorial
ZDB-ID	1045583-8
ISSN	1433-8491 ; 0175-758X ; 0940-1334
ISSN (online)	1433-8491
ISSN	0175-758X ; 0940-1334
DOI	10.1007/s00406-020-01130-1
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Article ; Online: Real-life social interactions in schizophrenia.

Myin-Germeys, Inez

Schizophrenia research

2019 Volume 216, Page(s) 10–11

MeSH term(s)	Cognition ; Humans ; Schizophrenia ; Schizophrenic Psychology ; Social Adjustment ; Social Behavior ; Social Interaction ; Social Perception
Language	English
Publishing date	2019-12-07
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639422-x
ISSN	1573-2509 ; 0920-9964
ISSN (online)	1573-2509
ISSN	0920-9964
DOI	10.1016/j.schres.2019.11.042
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Zs.A 2351: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Investigating Receptivity and Affect Using Machine Learning: Ecological Momentary Assessment and Wearable Sensing Study.

King, Zachary D / Yu, Han / Vaessen, Thomas / Myin-Germeys, Inez / Sano, Akane

JMIR mHealth and uHealth

2024 Volume 12, Page(s) e46347

Abstract: Background: As mobile health (mHealth) studies become increasingly productive owing to the advancements in wearable and mobile sensor technology, our ability to monitor and model human behavior will be constrained by participant receptivity. Many health ...

Abstract	Background: As mobile health (mHealth) studies become increasingly productive owing to the advancements in wearable and mobile sensor technology, our ability to monitor and model human behavior will be constrained by participant receptivity. Many health constructs are dependent on subjective responses, and without such responses, researchers are left with little to no ground truth to accompany our ever-growing biobehavioral data. This issue can significantly impact the quality of a study, particularly for populations known to exhibit lower compliance rates. To address this challenge, researchers have proposed innovative approaches that use machine learning (ML) and sensor data to modify the timing and delivery of surveys. However, an overarching concern is the potential introduction of biases or unintended influences on participants' responses when implementing new survey delivery methods. Objective: This study aims to demonstrate the potential impact of an ML-based ecological momentary assessment (EMA) delivery system (using receptivity as the predictor variable) on the participants' reported emotional state. We examine the factors that affect participants' receptivity to EMAs in a 10-day wearable and EMA-based emotional state-sensing mHealth study. We study the physiological relationships indicative of receptivity and affect while also analyzing the interaction between the 2 constructs. Methods: We collected data from 45 healthy participants wearing 2 devices measuring electrodermal activity, accelerometer, electrocardiography, and skin temperature while answering 10 EMAs daily, containing questions about perceived mood. Owing to the nature of our constructs, we can only obtain ground truth measures for both affect and receptivity during responses. Therefore, we used unsupervised and supervised ML methods to infer affect when a participant did not respond. Our unsupervised method used k-means clustering to determine the relationship between physiology and receptivity and then inferred the emotional state during nonresponses. For the supervised learning method, we primarily used random forest and neural networks to predict the affect of unlabeled data points as well as receptivity. Results: Our findings showed that using a receptivity model to trigger EMAs decreased the reported negative affect by >3 points or 0.29 SDs in our self-reported affect measure, scored between 13 and 91. The findings also showed a bimodal distribution of our predicted affect during nonresponses. This indicates that this system initiates EMAs more commonly during states of higher positive emotions. Conclusions: Our results showed a clear relationship between affect and receptivity. This relationship can affect the efficacy of an mHealth study, particularly those that use an ML algorithm to trigger EMAs. Therefore, we propose that future work should focus on a smart trigger that promotes EMA receptivity without influencing affect during sampled time points.
MeSH term(s)	Humans ; Ecological Momentary Assessment ; Machine Learning ; Emotions ; Affect ; Wearable Electronic Devices
Language	English
Publishing date	2024-02-07
Publishing country	Canada
Document type	Journal Article
ZDB-ID	2719220-9
ISSN	2291-5222 ; 2291-5222
ISSN (online)	2291-5222
ISSN	2291-5222
DOI	10.2196/46347
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Article ; Online: Using Experience Sampling Methods to support clinical management of psychosis: The perspective of people with lived experience.

de Thurah, Lena / Kiekens, Glenn / Sips, Rob / Teixeira, Ana / Kasanova, Zuzana / Myin-Germeys, Inez

Psychiatry research

2023 Volume 324, Page(s) 115207

Abstract: The Experience sampling method (ESM) has the potential to support person-centered care of psychotic disorders. However, clinical implementation is hampered by a lack of user involvement in the design of ESM tools. This qualitative study explored the ... ...

Abstract	The Experience sampling method (ESM) has the potential to support person-centered care of psychotic disorders. However, clinical implementation is hampered by a lack of user involvement in the design of ESM tools. This qualitative study explored the perspective of nine people with lived experiences of psychosis. Participants reported a need to monitor a diverse range of daily-life experiences and indicated that ESM should allow for personalization to be clinically useful. While participants recognized the potential of ESM to increase awareness and control over their mental health, concerns were voiced about the validity and burden of monitoring one's own mental health.
MeSH term(s)	Humans ; Ecological Momentary Assessment ; Psychotic Disorders/therapy ; Psychotic Disorders/psychology ; Mental Health ; Life Change Events ; Qualitative Research
Language	English
Publishing date	2023-04-21
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2023.115207
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Article ; Online: Not just emotion regulation, but cognition: An experience sampling study testing the relations of ecological interpretation biases and use of emotion regulation strategies with momentary affective states during daily life functioning.

Boemo, Teresa / Martín-Garcia, Oscar / Pacheco-Romero, Ana Mar / Blanco, Ivan / Lafit, Ginette / Myin-Germeys, Inez / Sanchez-Lopez, Alvaro

Behaviour research and therapy

2024 , Page(s) 104550

Abstract: Background: Current research is moving from studying cognitive biases and maladaptive emotion regulation (ER) as relatively stable phenomena contributing to affective disturbances, adopting ecological methodologies, such as Experience Sampling Methods ( ... ...

Abstract	Background: Current research is moving from studying cognitive biases and maladaptive emotion regulation (ER) as relatively stable phenomena contributing to affective disturbances, adopting ecological methodologies, such as Experience Sampling Methods (ESM). However, there is still limited ESM evidence on the interactions between stress and ER strategies' use, and negative interpretation biases, regarding their relations with momentary affective states. In this study, we used a new ESM design to disentangle the contextual, regulatory and cognitive processes implicated in daily affective experiences. Method: A sample of 103 participants completed an ESM study (3 times a day for 10 days) that included self-reports of momentary affect, stress intensity, ER strategies' use and a cognitive task measuring momentary negative interpretation biases. Results: Multilevel analyses supported significant interactions of both rumination and worry with stress intensity, to account for momentary higher negative and lower positive affect levels. Furthermore, higher state negative interpretation bias levels uniquely predicted both higher negative and lower positive momentary affect levels. Conclusion: This study implemented a novel online cognitive task within an ESM procedure, which helped to disentangle how contextual ER strategies' use and momentary cognitive biases uniquely relate to affective experiences in daily life.
Language	English
Publishing date	2024-04-25
Publishing country	England
Document type	Journal Article
ZDB-ID	211997-3
ISSN	1873-622X ; 0005-7967
ISSN (online)	1873-622X
ISSN	0005-7967
DOI	10.1016/j.brat.2024.104550
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Article: Do loneliness and social exclusion breed paranoia? An experience sampling investigation across the psychosis continuum.

Bell, Victoria / Velthorst, Eva / Almansa, Jorge / Myin-Germeys, Inez / Shergill, Sukhi / Fett, Anne-Kathrin

Schizophrenia research. Cognition

2023 Volume 33, Page(s) 100282

Abstract: Background: The role of loneliness and social exclusion in the development of paranoia is largely unexplored. Negative affect may mediate potential associations between these factors. We investigated the temporal relationships of daily-life loneliness, ... ...

Abstract	Background: The role of loneliness and social exclusion in the development of paranoia is largely unexplored. Negative affect may mediate potential associations between these factors. We investigated the temporal relationships of daily-life loneliness, felt social exclusion, negative affect, and paranoia across the psychosis continuum. Method: Seventy-five participants, including 29 individuals with a diagnosis of non-affective psychosis, 20 first-degree relatives, and 26 controls used an Experience Sampling Method (ESM) app to capture the fluctuations in loneliness, feelings of social exclusion, paranoia, and negative affect across a 1-week period. Data were analysed with multilevel regression analyses. Results: In all groups, loneliness and feelings of social exclusion were independent predictors of paranoia over time (b = 0.05, Conclusion: Paranoia and negative affect worsen in all groups following feelings of loneliness and social exclusion. This highlights the importance of a sense of belonging and being included for mental well-being. Loneliness, feeling socially excluded, and negative affect were independent predictors of paranoid thinking, suggesting they represent useful targets in its treatment.
Language	English
Publishing date	2023-03-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2800609-4
ISSN	2215-0013
ISSN	2215-0013
DOI	10.1016/j.scog.2023.100282
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Article: Reported Affect Changes as a Function of Response Delay: Findings From a Pooled Dataset of Nine Experience Sampling Studies.

Eisele, Gudrun / Vachon, Hugo / Myin-Germeys, Inez / Viechtbauer, Wolfgang

Frontiers in psychology

2021 Volume 12, Page(s) 580684

Abstract: Delayed responses are a common phenomenon in experience sampling studies. Yet no consensus exists on whether they should be excluded from the analysis or what the threshold for exclusion should be. Delayed responses could introduce bias, but previous ... ...

Abstract	Delayed responses are a common phenomenon in experience sampling studies. Yet no consensus exists on whether they should be excluded from the analysis or what the threshold for exclusion should be. Delayed responses could introduce bias, but previous investigations of systematic differences between delayed and timely responses have offered unclear results. To investigate differences as a function of delay, we conducted secondary analyses of nine paper and pencil based experience sampling studies including 1,528 individuals with different clinical statuses. In all participants, there were significant decreases in positive and increases in negative affect as a function of delay. In addition, delayed answers of participants without depression showed higher within-person variability and an initial strengthening in the relationships between contextual stress and affect. Participants with depression mostly showed the opposite pattern. Delayed responses seem qualitatively different from timely responses. Further research is needed to understand the mechanisms underlying these differences.
Language	English
Publishing date	2021-02-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2021.580684
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Article ; Online: Is theory of mind a prerequisite for social interactions? A study in psychotic disorder.

Schneider, Maude / Myin, Erik / Myin-Germeys, Inez

Psychological medicine

2019 Volume 50, Issue 5, Page(s) 754–760

Abstract: Background: A dominant idea is that impaired capacities for theory of mind (ToM) are the reasons for impairments in social functioning in several conditions, including autism and schizophrenia. In this paper, we present empirical evidence that ... ...

Abstract	Background: A dominant idea is that impaired capacities for theory of mind (ToM) are the reasons for impairments in social functioning in several conditions, including autism and schizophrenia. In this paper, we present empirical evidence that challenges this influential assumption. Methods: We conducted three studies examining the association between ToM and social functioning in participants diagnosed with a non-affective psychotic disorder and healthy individuals. We used both the experience sampling method, a structured diary technique collecting information in daily-life, and a standardised questionnaire to assess social functioning. Analysed data are part of Wave 1 and Wave 3 of the Genetic Risk and Outcome of Psychosis (GROUP) study. Results: Results were highly consistent across studies and showed no significant association between the two constructs. Conclusions: These findings question the leading assumption that social cognition is a prerequisite for social functioning, but rather suggest that social cognition is possibly a result of basic social interactive capacities.
MeSH term(s)	Adolescent ; Adult ; Female ; Humans ; Male ; Middle Aged ; Neuropsychological Tests ; Psychotic Disorders/psychology ; Schizophrenic Psychology ; Social Interaction ; Surveys and Questionnaires ; Theory of Mind ; Young Adult
Language	English
Publishing date	2019-03-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	217420-0
ISSN	1469-8978 ; 0033-2917
ISSN (online)	1469-8978
ISSN	0033-2917
DOI	10.1017/S0033291719000540
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Article ; Online: Is daily-life stress reactivity a measure of stress recovery? An investigation of laboratory and daily-life stress.

De Calheiros Velozo, Joana / Vaessen, Thomas / Lafit, Ginette / Claes, Stephan / Myin-Germeys, Inez

Stress and health : journal of the International Society for the Investigation of Stress

2022 Volume 39, Issue 3, Page(s) 638–650

Abstract: Typical measures of laboratory reactivity (i.e. difference between control and stress) and recovery (i.e. difference between stress and post-stress) were compared with a conventional measure of daily-life reactivity, best known as event-related stress. ... ...

Abstract	Typical measures of laboratory reactivity (i.e. difference between control and stress) and recovery (i.e. difference between stress and post-stress) were compared with a conventional measure of daily-life reactivity, best known as event-related stress. Fifty-three healthy individuals between 19 and 35 years of age took part in a laboratory session where stress was induced using the repeated Montreal Imaging Stress Task and 8 days of experience sampling method. Measures of negative affect, heart rate (HR), HR variability, and skin conductance level were collected. Findings show no strong associations between laboratory and daily life measures with the exception of laboratory affective recovery and daily life reactivity. Findings and their implications are discussed.
MeSH term(s)	Humans ; Stress, Psychological/psychology ; Heart Rate/physiology ; Ecological Momentary Assessment
Language	English
Publishing date	2022-12-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2042041-9
ISSN	1532-2998 ; 1532-3005
ISSN (online)	1532-2998
ISSN	1532-3005
DOI	10.1002/smi.3213
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