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  1. Article ; Online: La inclusión del tiempo en la estructura espacial de Jorge E. Eielson y su expresión plástica a través de la intervención en materiales textiles

    María Milagros Rodríguez Canales

    Tesis (Lima), Vol 13, Iss 16, Pp 169-

    2020  Volume 188

    Abstract: En el presente artículo, se analiza la existencia de una estructura espacial en la obra de Jorge ... del fenómeno espacial y que ello obtiene un co-relato en la obra plástica a partir de la intervención ... así como su tránsito hacia formas concretas a través de operaciones materiales sobre telas. ...

    Abstract En el presente artículo, se analiza la existencia de una estructura espacial en la obra de Jorge Eduardo Eielson. Se propone que su sistema incluye la concepción del tiempo como parte integrante del fenómeno espacial y que ello obtiene un co-relato en la obra plástica a partir de la intervención en materiales textiles. Por ello, la exploración del espacio se realizará considerando las nociones abstractas que Eielson desarrolla sobre el mismo, recogidas de sus ensayos, entrevistas y proyectos no objetuales; así como su tránsito hacia formas concretas a través de operaciones materiales sobre telas.
    Keywords espacio ; espacio-tiempo ; textil ; History of scholarship and learning. The humanities ; AZ20-999 ; Literature (General) ; PN1-6790 ; Arts in general ; NX1-820
    Language Spanish
    Publishing date 2020-06-01T00:00:00Z
    Publisher Universidad Nacional Mayor de San Marcos, Facultad de Letras y Ciencias Humanas
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Lossio, Jorge. El peruano y su entorno. Aclimatándose a las alturas andinas . Lima, Instituto de Estudios Peruanos, 2012. 119 páginas [ISBN

    Caycho Rodríguez, Tomás

    Asclepio: Revista de Historia de la Medicina y de la Ciencia, Vol 67, Iss 1, p p

    978-9972-51-362-6]

    2015  Volume 092

    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; History of medicine. Medical expeditions ; R131-687
    Language English
    Publishing date 2015-06-01T00:00:00Z
    Publisher Consejo Superior de Investigaciones Científicas
    Document type Article ; Online
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  3. Article ; Online: Lossio, Jorge. El peruano y su entorno. Aclimatándose a las alturas andinas. Lima, Instituto de Estudios Peruanos, 2012. 119 páginas [ISBN

    Tomás Caycho Rodríguez

    Asclepio: Revista de Historia de la Medicina y de la Ciencia, Vol 67, Iss 1, Pp p092-p

    978-9972-51-362-6]

    2015  Volume 092

    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; History of medicine. Medical expeditions ; R131-687
    Language English
    Publishing date 2015-06-01T00:00:00Z
    Publisher Consejo Superior de Investigaciones Científicas
    Document type Article ; Online
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  4. Article ; Online: Photobiomodulation increases brain metabolic activity through a combination of 810 and 660 wavelengths: a comparative study in male and female rats.

    Zorzo, Candela / Rodríguez-Fernández, Lucía / Martínez, Juan A / Arias, Jorge L

    Lasers in medical science

    2024  Volume 39, Issue 1, Page(s) 26

    Abstract: Photobiomodulation (PBM), an emerging and non-invasive intervention, has been shown to benefit the nervous system by modifying the mitochondrial cytochrome c-oxidase (CCO) enzyme, which has red (620-680 nm) or infrared (760-825 nm) spectral absorption ... ...

    Abstract Photobiomodulation (PBM), an emerging and non-invasive intervention, has been shown to benefit the nervous system by modifying the mitochondrial cytochrome c-oxidase (CCO) enzyme, which has red (620-680 nm) or infrared (760-825 nm) spectral absorption peaks. The effect of a single 810-nm wavelength with a combination of 810 nm and 660 nm lights in the brain metabolic activity of male and female rats was compared. PBM, with a wavelength of 810 nm and a combination of 810 nm and 660 nm, was applied for 5 days on the prefrontal cortex. Then, brain metabolic activity in the prefrontal area, hippocampus, retrosplenial, and parietal cortex was explored. Sex differences were found in cortical and subcortical regions, indicating higher male brain oxidative metabolism, regardless of treatment. CCO activity in the cingulate and prelimbic area, dentate gyrus, retrosplenial and parietal cortex was enhanced in both treatments (810 + 660 nm and 810 nm). Moreover, using the combination of waves, CCO increased in the infralimbic area, and in CA1 and CA3 of the hippocampus. Thus, employment of a single NIR treatment or a combination of red to NIR treatment led to slight differences in CCO activity across the limbic system, suggesting that a combination of lights of the spectrum may be relevant.
    MeSH term(s) Rats ; Male ; Female ; Animals ; Low-Level Light Therapy ; Electron Transport Complex IV/metabolism ; Oxidation-Reduction ; Brain/metabolism ; Hippocampus/metabolism
    Chemical Substances Electron Transport Complex IV (EC 1.9.3.1)
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 632808-8
    ISSN 1435-604X ; 0268-8921
    ISSN (online) 1435-604X
    ISSN 0268-8921
    DOI 10.1007/s10103-023-03966-0
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  5. Article: Guidelines on epidemics in Mexico. Historical perspective.

    Rodríguez-Pérez, Martha E / Ramírez-Hernández, Jorge A / Ruelas-Barajas, Enrique

    Gaceta medica de Mexico

    2023  Volume 159, Issue 1, Page(s) 74–80

    Abstract: A perspective of epidemics and pandemics in Mexico is offered, focusing on three time periods, namely, end of the ... ...

    Title translation Directrices en torno a las epidemias en México. Perspectiva histórica.
    Abstract A perspective of epidemics and pandemics in Mexico is offered, focusing on three time periods, namely, end of the 18
    MeSH term(s) Humans ; Mexico/epidemiology ; Influenza, Human/epidemiology ; Pandemics ; Government ; Referral and Consultation
    Language English
    Publishing date 2023-03-17
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.M22000742
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  6. Article ; Online: Immobilized mesoporous materials for carvacrol delivery to the germination and early growth of tomato plants (Solanum Lycopersicum).

    Esquivel-Castro, Tzipatly A / Oliva, Jorge / Rodríguez-González, Vicente / Rosu, Haret C

    Environmental research

    2023  Volume 228, Page(s) 115860

    Abstract: The immobilization of ... ...

    Abstract The immobilization of TiO
    MeSH term(s) Germination ; Solanum lycopersicum ; Silicon Dioxide ; Seeds
    Chemical Substances triethanolamine (9O3K93S3TK) ; carvacrol (9B1J4V995Q) ; Silicon Dioxide (7631-86-9)
    Language English
    Publishing date 2023-04-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.115860
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  7. Article: Case report: effect of umbilical cord mesenchymal stem cells on immunoglobulin A nephropathy after acute renal failure.

    Riordan, Neil H / Ambrozic, Richard A / Paz-Rodríguez, Jorge

    American journal of translational research

    2022  Volume 14, Issue 7, Page(s) 4855–4859

    Abstract: Immunoglobulin A nephropathy is an inflammatory, autoimmune condition that may lead to renal impairment in its most aggressive forms. In this case report, a 50-year-old male with acute renal failure was diagnosed with IgA nephropathy, having elevated ... ...

    Abstract Immunoglobulin A nephropathy is an inflammatory, autoimmune condition that may lead to renal impairment in its most aggressive forms. In this case report, a 50-year-old male with acute renal failure was diagnosed with IgA nephropathy, having elevated creatinine levels (3.0 mg/dL) and hypertension. He received intravenous infusions of a total of 120 million umbilical cord-derived mesenchymal stem cells (UC-MSCs) and was followed-up for 6 months. No adverse events were reported during or after administration or any of the follow-up visits. Creatinine levels decreased to and remained normal (1.0 mg/dL) in the 6 months following treatment. Anti-hypertensive medications were no longer needed. UC-MSC administration was safe, well-tolerated, and beneficial for this patient with IgA nephropathy.
    Language English
    Publishing date 2022-07-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
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  8. Article ; Online: Involvement of Akt and the antiapoptotic protein Bcl-xL in the inhibition of apoptosis of dendritic cells by Leishmania mexicana.

    Rodríguez-González, Jorge / Wilkins-Rodríguez, Arturo A / Gutiérrez-Kobeh, Laila

    Parasite immunology

    2022  Volume 44, Issue 7, Page(s) e12917

    Abstract: The intracellular parasite Leishmania mexicana inhibits camptothecin (CPT)-induced apoptosis of monocyte-derived dendritic cells (moDC) through the down-regulation of p38 and JNK phosphorylation, while the kinase Akt is maintained active for 24 h. In ... ...

    Abstract The intracellular parasite Leishmania mexicana inhibits camptothecin (CPT)-induced apoptosis of monocyte-derived dendritic cells (moDC) through the down-regulation of p38 and JNK phosphorylation, while the kinase Akt is maintained active for 24 h. In addition, the infection of moDC with L. mexicana promastigotes increases the protein presence of the antiapoptotic protein Bcl-xL. In the present work, we aimed to investigate the role of Akt in the inhibition of apoptosis of moDC by L. mexicana and in the modulation of the expression of the antiapoptotic proteins Bcl-2, Mcl-1 and Bcl-xL. moDC were infected with L. mexicana metacyclic promastigotes and treated with CPT, an Akt inhibitor, or both and the mitochondrial outer membrane permeabilization (MOMP) and protein presence of active caspase 3, Bcl-2, Mcl-1 and Bcl-xL were evaluated. Our results show that the specific inhibition of Akt reverts the apoptosis protective effect exerted by L. mexicana on moDC reflected by a reduction in MOMP, caspase 3 activation, and upregulation of Bcl-xL. Interestingly, we also found that the infection of moDC with L. mexicana promastigotes induces a decrease in Bcl-2 along with an isoform change of Mcl-1, this independently to Akt activity. We demonstrated that Akt is deeply involved in the inhibition of apoptosis of moDC by L. mexicana.
    MeSH term(s) Apoptosis ; Apoptosis Regulatory Proteins ; Camptothecin/pharmacology ; Caspase 3 ; Dendritic Cells/parasitology ; Leishmania mexicana/physiology ; Myeloid Cell Leukemia Sequence 1 Protein ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-akt/pharmacology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-2/pharmacology ; bcl-X Protein/metabolism
    Chemical Substances Apoptosis Regulatory Proteins ; Myeloid Cell Leukemia Sequence 1 Protein ; Proto-Oncogene Proteins c-bcl-2 ; bcl-X Protein ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Caspase 3 (EC 3.4.22.-) ; Camptothecin (XT3Z54Z28A)
    Language English
    Publishing date 2022-04-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424444-8
    ISSN 1365-3024 ; 0141-9838
    ISSN (online) 1365-3024
    ISSN 0141-9838
    DOI 10.1111/pim.12917
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    Zs.A 1509: Show issues Location:
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  9. Article ; Online: Synaptic remodeling of GluA1 and GluA2 expression in the nucleus accumbens promotes susceptibility to cognitive deficits concomitant with downstream GSK3

    Memos, Nicoletta / Avila, Jorge A / Rodriguez, Edgar / Serrano, Peter A

    Addiction neuroscience

    2023  Volume 8

    Abstract: Stimulant-use disorders can present with long-term cognitive and mental health deficits. Little is known about the underlying molecular mechanisms perpetuating sex differences in cognitive and behavioral deficits in preclinical models of addiction to ... ...

    Abstract Stimulant-use disorders can present with long-term cognitive and mental health deficits. Little is known about the underlying molecular mechanisms perpetuating sex differences in cognitive and behavioral deficits in preclinical models of addiction to stimulants such as methamphetamine (MA). The current study investigated the neurochemical shifts underlying sex disparities in MA-induced working memory deficits and an addictive phenotype following abstinence from chronic MA abuse. We used our previously reported mouse model of voluntary oral methamphetamine administration (VOMA) consisting of an acquisition phase (days 1-14) characterized by escalating doses of MA and a binge phase (days 14-28) characterized by static doses. Female VOMA mice exhibited sustained MA consumption during the binge phase, demonstrating sex-specific vulnerabilities to the maintenance of MA addiction. The 8-arm radial maze was used to test spatial working memory performance following abstinence from VOMA. Results indicate working memory deficits correlated to higher MA consumption in females only. Hippocampal and accumbal tissue were collected and analyzed by immunoblotting. Female VOMA mice had decreased GluA1, but not GluA2, in the hippocampus, which may perpetuate synaptic destabilization and working memory deficits. Female-specific increases in GluA1 and p-GSK3
    Language English
    Publishing date 2023-06-16
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-3925
    ISSN (online) 2772-3925
    DOI 10.1016/j.addicn.2023.100112
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  10. Article ; Online: Race and Odds of Surgery Offer in Small Bowel and Pancreas Neuroendocrine Neoplasms.

    Zarate Rodriguez, Jorge G / Raper, Lacey / Sanford, Dominic E / Trikalinos, Nikolaos A / Hammill, Chet W

    Annals of surgical oncology

    2024  Volume 31, Issue 5, Page(s) 3249–3260

    Abstract: Background: Despite existing society guidelines, management of pancreatic (PanNEN) and small bowel (SBNEN) neuroendocrine neoplasms remains inconsistent. The purpose of this study was to identify patient- and/or disease-specific characteristics ... ...

    Abstract Background: Despite existing society guidelines, management of pancreatic (PanNEN) and small bowel (SBNEN) neuroendocrine neoplasms remains inconsistent. The purpose of this study was to identify patient- and/or disease-specific characteristics associated with increased odds of being offered surgery for PanNEN and SBNEN.
    Patients and methods: The Surveillance, Epidemiology, and End Results (SEER) Program database and the National Cancer Database (NCDB) were queried for patients with PanNEN/SBNEN. Demographic and pathologic data were compared between patients who were offered surgery and those who were not. Multivariate logistic regression was performed to identify factors independently associated with being offered surgery.
    Results: In SEER, there were 3641 patients with PanNEN (54.7% were offered surgery) and 5720 with SBNEN (86.0% were offered surgery). On multivariate analysis of SEER, non-white race was associated with decreased odds of surgery offer for SBNEN [odds ratio (OR) 0.58, p < 0.001], but not PanNEN (p = 0.187). In NCDB, there were 28,483 patients with PanNEN (57.5% were offered surgery) and 42,675 with SBNEN (86.9% were offered surgery). On multivariate analysis of NCDB, non-white race was also associated with decreased odds of surgery offer for SBNEN (OR 0.61, p < 0.001) but not PanNEN (p = 0.414).
    Conclusions: This study's findings suggest that, in addition to previously reported disparities in surgical resection and surgery refusal rates, racial/ethnic disparities also exist earlier in the course of treatment, with non-white patients being less likely to be offered surgery for SBNEN but not for PanNEN; this is potentially due to discrepancies in rates of referral to academic centers for pancreas and small bowel malignancies.
    MeSH term(s) Humans ; White People ; SEER Program ; Pancreatic Neoplasms/pathology ; Duodenal Neoplasms ; Neuroendocrine Tumors/surgery ; Pancreas/pathology
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-024-14906-9
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