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Article: Emily J. Su, M.D., M.S.

Carr, Bruce R.

(The Important Role of Estrogen Receptor-β in Women’s Health)

2012 Volume 30, Issue 01, Page(s) 1–2

Series title	The Important Role of Estrogen Receptor-β in Women’s Health
Language	English
Publishing date	2012-01-01
Publisher	Thieme Medical Publishers
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2042479-6
ISSN	1526-4564 ; 1526-8004
ISSN (online)	1526-4564
ISSN	1526-8004
DOI	10.1055/s-0031-1299590
Database	Thieme publisher's database

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Article ; Online: Genome sequence of Soos: a siphovirus of the CP cluster infecting

Adams, Reese M / Britton, Holly A / Bruce, Emily D / De La Paz, Yucita / Kratz, Emily N / Pfeifer, Emma J / Priddy, Daisy E / Schotter, Brooklyn I / Stuffle, Wyatt A / Wagner, Jordyn / Weiss, Meredith R / Watt, Danielle K / Connerly, Pamela L / Rueschhoff, Elizabeth E

Microbiology resource announcements

2024 Volume 13, Issue 4, Page(s) e0120423

Abstract: Novel actinobacteriophage Soos was isolated and purified from Southern Indiana soil using ... ...

Abstract	Novel actinobacteriophage Soos was isolated and purified from Southern Indiana soil using host
Language	English
Publishing date	2024-03-25
Publishing country	United States
Document type	Journal Article
ISSN	2576-098X
ISSN (online)	2576-098X
DOI	10.1128/mra.01204-23
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A liposomal bupivacaine infiltrative block reduces rescue analgesia administration compared to a bupivacaine splash block after canine ovariohysterectomy in a teaching laboratory.

Wheeler, Emily P / Abelson, Amanda L / Paul, April L / Barton, Bruce A / McCobb, Emily C

Journal of the American Veterinary Medical Association

2023 Volume 261, Issue 11, Page(s) 1673–1682

Abstract: Objective: This study aimed to determine whether an infiltrative block with liposomal bupivacaine was associated with less rescue analgesia administration and lower pain scores than a bupivacaine splash block after ovariohysterectomy in dogs.: Animals! ...

Abstract	Objective: This study aimed to determine whether an infiltrative block with liposomal bupivacaine was associated with less rescue analgesia administration and lower pain scores than a bupivacaine splash block after ovariohysterectomy in dogs. Animals: Eligible dogs included those that were spayed as part of a veterinary teaching laboratory. Dogs were up to 7 years old and otherwise healthy. A total of 136 dogs were analyzed. Methods: All dogs underwent ovariohysterectomy performed by veterinary students. Dogs received hydromorphone and acepromazine premedication, propofol induction, isoflurane maintenance, and an NSAID. Dogs were randomly allocated to receive either a splash block with standard bupivacaine or an infiltrative block with liposomal bupivacaine for incisional analgesia. Postoperatively, all dogs were assessed by a blinded evaluator using the Colorado State University-Canine Acute Pain Scale (CSU-CAPS) and Glasgow Composite Measures Pain Scale-Short Form (GCPS-SF). Dogs received rescue analgesia with buprenorphine if they scored ≥ 2 on the CSU-CAPS scale. Results: Dogs that received liposomal bupivacaine had a significantly lower incidence of (P = .04) and longer time to (P = .03) administration of rescue analgesia. There was an overall time-averaged significant difference between groups for CSU-CAPS (P = .049) and GCPS-SF scores (P = .015), with dogs in the bupivacaine group being more likely to have an elevated pain score at some point for both scales. Clinical relevance: The use of liposomal bupivacaine in an infiltrative block may decrease the need for rescue analgesia in dogs undergoing ovariohysterectomy compared to a bupivacaine splash block.
MeSH term(s)	Animals ; Dogs ; Female ; Analgesia/veterinary ; Anesthetics, Local/therapeutic use ; Bupivacaine/therapeutic use ; Dog Diseases/drug therapy ; Dog Diseases/prevention & control ; Hysterectomy/veterinary ; Ovariectomy/veterinary ; Pain, Postoperative/drug therapy ; Pain, Postoperative/prevention & control ; Pain, Postoperative/veterinary ; Random Allocation
Chemical Substances	Anesthetics, Local ; Bupivacaine (Y8335394RO)
Language	English
Publishing date	2023-07-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.23.01.0057
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Article ; Online: Delabeling for the duration? β-Lactam prescribing in hospitalized patients after penicillin skin testing.

Bland, Christopher M / Heil, Emily L / Asbell, Ashley / Smith, Susan E / Jones, Bruce M

The journal of allergy and clinical immunology. In practice

2023 Volume 11, Issue 10, Page(s) 3245–3247

MeSH term(s)	Humans ; Penicillins/adverse effects ; beta-Lactams/adverse effects ; Anti-Bacterial Agents/adverse effects ; Skin Tests ; Patients ; Drug Hypersensitivity/diagnosis ; Drug Hypersensitivity/drug therapy
Chemical Substances	Penicillins ; beta-Lactams ; Anti-Bacterial Agents
Language	English
Publishing date	2023-06-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2843237-X
ISSN	2213-2201 ; 2213-2198
ISSN (online)	2213-2201
ISSN	2213-2198
DOI	10.1016/j.jaip.2023.06.019
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Article ; Online: Falling behind: The growth of frail, high-need beneficiaries receiving home based primary care in traditional Medicare 2014-2021.

Lally, Tom / Johnson, Emily / Deligiannidis, Konstantinos E / Taler, George / Boling, Peter / Yao, Aaron / Kubisiak, Joanna / Lee, Angelina / Kinosian, Bruce

Journal of the American Geriatrics Society

2024

Language	English
Publishing date	2024-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	80363-7
ISSN	1532-5415 ; 0002-8614
ISSN (online)	1532-5415
ISSN	0002-8614
DOI	10.1111/jgs.18820
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Article ; Online: Public health guidelines for physical activity during pregnancy from around the world: a scoping review.

Hayman, Melanie / Brown, Wendy J / Brinson, Alison / Budzynski-Seymour, Emily / Bruce, Tracy / Evenson, Kelly R

British journal of sports medicine

2023 Volume 57, Issue 14, Page(s) 940–947

Abstract: Background and objective: Despite the known health benefits of physical activity (PA), pregnancy is a time of marked decline in PA levels. To provide women with reliable and trustworthy information, and to encourage greater participation in PA during ... ...

Abstract	Background and objective: Despite the known health benefits of physical activity (PA), pregnancy is a time of marked decline in PA levels. To provide women with reliable and trustworthy information, and to encourage greater participation in PA during pregnancy, many governments have developed guidelines for PA during pregnancy. Our aim was to synthesise the most recent public health guidelines on PA during pregnancy from different countries in order to understand the nature and extent of advice that is available. Design: Scoping review. Data sources: Search of the grey literature, direct contact with international experts, screening of relevant academic literature and citation searching. Eligibility criteria: Public health guidelines developed or endorsed by government departments published since 2010. Results: Our search located 30 eligible guidelines, published in 11 different languages. There is remarkable concordance in the advice offered. For women with uncomplicated pregnancy, guidelines recommend: 150-300 min/week of moderate intensity aerobic activity; pelvic floor and muscle strengthening exercises; modification of some exercises (eg, supine position); and provide lists of warning signs to cease activity (eg, persistent dizziness, vaginal bleeding) and activities that should be avoided (eg, if high risk of falling/collision). Few guidelines offer specific advice for highly active women (eg, athletes), or trimester-specific or culturally specific considerations. Conclusions: This review provides a summary of public health recommendations for PA during pregnancy around the world. The challenge is now to ensure that all who provide healthcare for women understand the guidelines and encourage safe participation in PA during pregnancy.
MeSH term(s)	Pregnancy ; Female ; Humans ; Public Health ; Exercise ; Exercise Therapy
Language	English
Publishing date	2023-01-05
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	600592-5
ISSN	1473-0480 ; 0306-3674
ISSN (online)	1473-0480
ISSN	0306-3674
DOI	10.1136/bjsports-2022-105777
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Transformations of sensory information in the brain suggest changing criteria for optimality.

Manning, Tyler S / Alexander, Emma / Cumming, Bruce G / DeAngelis, Gregory C / Huang, Xin / Cooper, Emily A

PLoS computational biology

2024 Volume 20, Issue 1, Page(s) e1011783

Abstract: Neurons throughout the brain modulate their firing rate lawfully in response to sensory input. Theories of neural computation posit that these modulations reflect the outcome of a constrained optimization in which neurons aim to robustly and efficiently ... ...

Abstract	Neurons throughout the brain modulate their firing rate lawfully in response to sensory input. Theories of neural computation posit that these modulations reflect the outcome of a constrained optimization in which neurons aim to robustly and efficiently represent sensory information. Our understanding of how this optimization varies across different areas in the brain, however, is still in its infancy. Here, we show that neural sensory responses transform along the dorsal stream of the visual system in a manner consistent with a transition from optimizing for information preservation towards optimizing for perceptual discrimination. Focusing on the representation of binocular disparities-the slight differences in the retinal images of the two eyes-we re-analyze measurements characterizing neuronal tuning curves in brain areas V1, V2, and MT (middle temporal) in the macaque monkey. We compare these to measurements of the statistics of binocular disparity typically encountered during natural behaviors using a Fisher Information framework. The differences in tuning curve characteristics across areas are consistent with a shift in optimization goals: V1 and V2 population-level responses are more consistent with maximizing the information encoded about naturally occurring binocular disparities, while MT responses shift towards maximizing the ability to support disparity discrimination. We find that a change towards tuning curves preferring larger disparities is a key driver of this shift. These results provide new insight into previously-identified differences between disparity-selective areas of cortex and suggest these differences play an important role in supporting visually-guided behavior. Our findings emphasize the need to consider not just information preservation and neural resources, but also relevance to behavior, when assessing the optimality of neural codes.
MeSH term(s)	Animals ; Visual Cortex/physiology ; Macaca ; Vision Disparity ; Brain ; Neurons/physiology ; Photic Stimulation/methods
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2193340-6
ISSN	1553-7358 ; 1553-734X
ISSN (online)	1553-7358
ISSN	1553-734X
DOI	10.1371/journal.pcbi.1011783
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Article ; Online: Oncologist Perceptions of Racial Disparity, Racial Anxiety, and Unconscious Bias in Clinical Interactions, Treatment, and Outcomes.

Balanean, Alexandrina / Bland, Emily / Gajra, Ajeet / Jeune-Smith, Yolaine / Klink, Andrew J / Hays, Harlen / Feinberg, Bruce A

Journal of the National Comprehensive Cancer Network : JNCCN

2024 Volume 22, Issue 2, Page(s) 82–90

Abstract: Background: Cancer spares no demographic or socioeconomic group; it is indeed the great equalizer. But its distribution is not equal; when structural discrimination concentrates poverty and race, zip code surpasses genetic code in predicting outcomes. ... ...

Abstract	Background: Cancer spares no demographic or socioeconomic group; it is indeed the great equalizer. But its distribution is not equal; when structural discrimination concentrates poverty and race, zip code surpasses genetic code in predicting outcomes. Compared with White patients in the United States, Black patients are less likely to receive appropriate treatment and referral to clinical trials, genetic testing, or palliative care/hospice. Methods: In 2021, we administered a survey to 369 oncologists measuring differences in perceptions surrounding racial disparity, racial anxiety, and unconscious bias and adverse influence on clinical interactions, treatment, and outcomes for non-White patients. We analyzed responses by generational age group, sex/gender, race/ethnicity, US region, and selection of "decline to respond." Results: The most significant differences occurred by age group followed by race/ethnicity. Racial disparity was perceived as moderate to very high by 84% of millennial, 69% of Generation X, and 57% of baby boomer oncologists, who were also 86% more likely than millennials and 63% more likely than Generation Xers to perceive low/nonexistent levels of racial anxiety/unconscious bias. Conclusions: Most oncologists rarely or never perceived racial anxiety/unconscious bias as adversely influencing clinical treatment or survival outcomes in non-White patients, and White oncologists were 85% more likely than non-White oncologists to perceive rare/nonexistent influence on referral of non-White patients to palliative care/hospice. The discrepancy between 62% of oncologists perceiving moderate to very high levels of racial anxiety/unconscious bias and 37% associating them with adverse influence on non-White patients shows a disconnect, especially among older oncologists (baby boomers), who were also least likely to select the decline option. Together, these factors hinder effective patient-provider communication and result in differential care and outcomes. Oncologists should uncover their own perceptions surrounding racial disparity, racial anxiety, and unconscious bias and modify their behaviors accordingly. It is this simple-and this complicated. Cancer does not discriminate, and neither should cancer care.
MeSH term(s)	Humans ; United States ; Black or African American ; Bias, Implicit ; Neoplasms/therapy ; Oncologists ; Anxiety/etiology ; Anxiety/therapy ; White
Language	English
Publishing date	2024-02-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2250759-0
ISSN	1540-1413 ; 1540-1405
ISSN (online)	1540-1413
ISSN	1540-1405
DOI	10.6004/jnccn.2023.7078
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Article ; Online: Correction: Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil.

Akthar, Mumina / Nair, Nisha / Carter, Lucy M / Vital, Edward M / Sutton, Emily / McHugh, Neil / Bruce, Ian N / Reynolds, John A

Arthritis research & therapy

2023 Volume 25, Issue 1, Page(s) 160

Language	English
Publishing date	2023-09-04
Publishing country	England
Document type	Published Erratum
ZDB-ID	2107602-9
ISSN	1478-6362 ; 1478-6354
ISSN (online)	1478-6362
ISSN	1478-6354
DOI	10.1186/s13075-023-03160-1
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Article ; Online: Proactive or reactive? Neural oscillatory insight into the leader-follower dynamics of early infant-caregiver interaction.

Phillips, Emily A M / Goupil, Louise / Whitehorn, Megan / Bruce-Gardyne, Emma / Csolsim, Florian A / Marriott-Haresign, Ira / Wass, Sam V

Proceedings of the National Academy of Sciences of the United States of America

2023 Volume 120, Issue 15, Page(s) e2122481120

Abstract: We know that infants' ability to coordinate attention with others toward the end of the first year is fundamental to language acquisition and social cognition. Yet, we understand little about the neural and cognitive mechanisms driving infant attention ... ...

Abstract	We know that infants' ability to coordinate attention with others toward the end of the first year is fundamental to language acquisition and social cognition. Yet, we understand little about the neural and cognitive mechanisms driving infant attention in shared interaction: do infants play a proactive role in creating episodes of joint attention? Recording electroencephalography (EEG) from 12-mo-old infants while they engaged in table-top play with their caregiver, we examined the communicative behaviors and neural activity preceding and following infant- vs. adult-led joint attention. Infant-led episodes of joint attention appeared largely reactive: they were not associated with increased theta power, a neural marker of endogenously driven attention, and infants did not increase their ostensive signals before the initiation. Infants were, however, sensitive to whether their initiations were responded to. When caregivers joined their attentional focus, infants showed increased alpha suppression, a pattern of neural activity associated with predictive processing. Our results suggest that at 10 to 12 mo, infants are not routinely proactive in creating joint attention episodes yet. They do, however, anticipate behavioral contingency, a potentially foundational mechanism for the emergence of intentional communication.
MeSH term(s)	Adult ; Humans ; Infant ; Caregivers ; Cognition ; Language Development ; Communication ; Electroencephalography
Language	English
Publishing date	2023-04-04
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2122481120
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