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  1. Article ; Online: The First Case of Infectious Spondylitis Caused by

    Lim, Kyoung Ree / Son, Jun Seong / Moon, Soo-Youn

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 1

    Abstract: ... Gemella ... ...

    Abstract Gemella bergeri
    MeSH term(s) Male ; Humans ; Aged ; Gemella ; Gram-Positive Bacterial Infections ; Abscess ; Gram-Positive Cocci ; Spondylitis/diagnostic imaging
    Language English
    Publishing date 2023-01-11
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59010145
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  2. Article: Complete genome sequence of

    Kim, Jung-Ae / Jang, Hyun-Jun / Kim, Dae-Hyuk / Son, Youn Kyoung / Kim, Yangseon

    Journal of animal science and technology

    2023  Volume 65, Issue 5, Page(s) 1105–1109

    Abstract: Pedi coccus ... ...

    Abstract Pedi coccus acidilactici
    Language English
    Publishing date 2023-09-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2775231-8
    ISSN 2055-0391
    ISSN 2055-0391
    DOI 10.5187/jast.2022.e102
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  3. Article ; Online: Clinical characteristics of native vertebral osteomyelitis in patients with history of acupuncture.

    Lim, Kyoung Ree / Moon, Soo-Youn / Son, Jun Seong

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2023  Volume 29, Issue 12, Page(s) 1114–1118

    Abstract: Background: Considering that vertebral osteomyelitis (VO) can occur via various routes, it can be predicted that clinical characteristics may vary depending on the route of infection or risk factors of the disease. In this study, differences in clinical ...

    Abstract Background: Considering that vertebral osteomyelitis (VO) can occur via various routes, it can be predicted that clinical characteristics may vary depending on the route of infection or risk factors of the disease. In this study, differences in clinical characteristics, causative pathogens, clinical features and prognosis were investigated in patients of native vertebral osteomyelitis with history of acupuncture.
    Methods: This retrospective study was conducted at Kyung Hee University Hospital at Gangdong, Seoul. We extracted data of patients diagnosed with VO from May 2006 to February 2021 using an electronic database. Data on demography, clinical presentation, treatment, causative organisms and clinical outcomes were identified and compared according to the history of acupuncture.
    Results: A total of 100 patients with VO were reviewed, among which 34 patients had a history of acupuncture prior to the diagnosis of VO. The frequency of Gram-positive cocci (GPC) was significantly higher in the acupuncture group than in the non-acupuncture group (p = 0.016). Abscess was observed more frequently in the acupuncture group than in the non-acupuncture group (p = 0.01). There was no difference in neurological sequelae and recurrence between the two groups. There was no difference in mortality between the two groups. (p = 0.098) CONCLUSION: This study suggests that confirming a history of acupuncture may help predict the pathogen or clinical characteristics of the disease. If the patient has a history of acupuncture, GPC can be considered as the causative organism, and the findings that abscesses and surgical treatment are more common may be helpful in evaluating patients.
    MeSH term(s) Humans ; Retrospective Studies ; Prognosis ; Abscess ; Acupuncture Therapy/adverse effects ; Osteomyelitis/diagnosis
    Language English
    Publishing date 2023-08-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2023.08.008
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  4. Article ; Online: The role of infectious disease consultations in the management of patients with fever in a long-term care facility.

    Moon, Soo-Youn / Lim, Kyoung Ree / Son, Jun Seong

    PloS one

    2023  Volume 18, Issue 9, Page(s) e0291421

    Abstract: Background: Infectious disease (ID) clinicians can provide essential services for febrile patients in tertiary hospitals. The aim of this study was to evaluate the role of ID consultations (IDC) in managing hospitalized patients with infections in an ... ...

    Abstract Background: Infectious disease (ID) clinicians can provide essential services for febrile patients in tertiary hospitals. The aim of this study was to evaluate the role of ID consultations (IDC) in managing hospitalized patients with infections in an oriental medical hospital (OMH), which serves as a long-term care facility. To our knowledge, this is the first study on the role of IDCs in managing patients in an OMH.
    Methods: This retrospective study was conducted in an OMH in Seoul, Korea, from June 2006 to June 2013.
    Results: Among the 465 cases of hospital-acquired fever, 141 (30.3%) were referred for ID. The most common cause of fever was infection in both groups. The peak body temperature of the patient was higher in IDC group (38.8±0.6°C vs. 38.6±0.5°C, p<0.001). Crude mortality at 30 days (14.6% vs. 7.8%, p = 0.043) and infection-attributable mortality (15.3% vs. 6.7%, p = 0.039) were higher in the No-IDC group. Multivariable analysis showed that infection as the focus of fever (adjusted Odd ratio [aOR] 3.49, 95% confidence interval (CI) 1.64-7.44), underlying cancer (aOR 10.32, 95% CI 4.34-24.51,), and multiorgan dysfunction syndrome (aOR 15.68, 95% CI 2.06-119.08) were associated with increased 30-day mortality. Multivariate analysis showed that in patients with infectious fever, appropriate antibiotic therapy (aOR 0.19, 95% CI 0.05-0.76) was the only factor associated with decreased infection-attributable mortality while underlying cancer (aOR 7.80, 95% CI 2.555-23.807) and severe sepsis or septic shock at the onset of fever (aOR 10.15, 95% CI 1.00-102.85) were associated with increased infection-attributable mortality.
    Conclusion: Infection was the most common cause of fever in patients hospitalized for OMH. Infection as the focus of fever, underlying cancer, and MODS was associated with increased 30-day mortality in patients with nosocomial fever. Appropriate antibiotic therapy was associated with decreased infection-attributable mortality in patients with infectious fever.
    MeSH term(s) Humans ; Long-Term Care ; Retrospective Studies ; Nursing Homes ; Fever ; Referral and Consultation ; Tertiary Care Centers ; Cardiomyopathy, Dilated ; Communicable Diseases/therapy
    Language English
    Publishing date 2023-09-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0291421
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  5. Article ; Online: Complete genome sequence and potential pathogenic assessment of Flavobacterium plurextorum RSG-18 isolated from the gut of Schlegel's black rockfish, Sebastes schlegelii.

    Lee, Jisol / Cha, In-Tae / Lee, Ki-Eun / Son, Youn Kyoung / Cho, Seoae / Seol, Donghyeok

    Environmental microbiology reports

    2024  Volume 16, Issue 1, Page(s) e13226

    Abstract: Flavobacterium plurextorum is a potential fish pathogen of interest, previously isolated from diseased rainbow trout (Oncorhynchus mykiss) and oomycete-infected chum salmon (Oncorhynchus keta) eggs. We report here the first complete genome sequence of F. ...

    Abstract Flavobacterium plurextorum is a potential fish pathogen of interest, previously isolated from diseased rainbow trout (Oncorhynchus mykiss) and oomycete-infected chum salmon (Oncorhynchus keta) eggs. We report here the first complete genome sequence of F. plurextorum RSG-18 isolated from the gut of Schlegel's black rockfish (Sebastes schlegelii). The genome of RSG-18 consists of a circular chromosome of 5,610,911 bp with a 33.57% GC content, containing 4858 protein-coding genes, 18 rRNAs, 63 tRNAs and 1 tmRNA. A comparative analysis was conducted on 11 Flavobacterium species previously reported as pathogens or isolated from diseased fish to confirm the potential pathogenicity of RSG-18. In the SEED classification, RSG-18 was found to have 36 genes categorized in 'Virulence, Disease and Defense'. Across all Flavobacterium species, a total of 16 antibiotic resistance genes and 61 putative virulence factors were identified. All species had at least one phage region and type I, III and IX secretion systems. In pan-genomic analysis, core genes consist of genes linked to phages, integrases and matrix-tolerated elements associated with pathology. The complete genome sequence of F. plurextorum RSG-18 will serve as a foundation for future research, enhancing our understanding of Flavobacterium pathogenicity in fish and contributing to the development of effective prevention strategies.
    MeSH term(s) Animals ; Flavobacterium/genetics ; Perciformes ; Virulence/genetics ; Virulence Factors/genetics ; Fishes/microbiology ; Bacteriophages ; Fish Diseases/microbiology ; Oncorhynchus mykiss/microbiology
    Chemical Substances Virulence Factors
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ISSN 1758-2229
    ISSN (online) 1758-2229
    DOI 10.1111/1758-2229.13226
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  6. Article ; Online: Qualitative and Quantitative Analysis of the Major Bioactive Components of

    Lim, Da Jung / Song, Jeong-Sup / Lee, Byoung-Hee / Son, Youn Kyoung / Kim, Yangseon

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 9

    Abstract: Plants in the ... ...

    Abstract Plants in the genus
    MeSH term(s) Chromatography, Liquid ; Spectrometry, Mass, Electrospray Ionization/methods ; Tandem Mass Spectrometry/methods ; Quercetin/analysis ; Juniperus/chemistry ; Chromatography, High Pressure Liquid/methods ; Flavonoids/chemistry ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Lignans/pharmacology ; Lignans/analysis ; Bacteria ; Anti-Bacterial Agents/pharmacology
    Chemical Substances Quercetin (9IKM0I5T1E) ; Flavonoids ; Plant Extracts ; Lignans ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-05-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28093937
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  7. Article ; Online: Case Report of Infectious Spondylitis Caused by

    Lim, Kyoung Ree / Son, Jun Seong / Moon, Soo-Youn

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 8

    Abstract: Background: Kytococcus: Case presentation: A 79-year-old female patient was hospitalized because of back pain for several months. She was diagnosed with infectious spondylitis, and : Conclusion: This is the first case report of infectious ... ...

    Abstract Background: Kytococcus
    Case presentation: A 79-year-old female patient was hospitalized because of back pain for several months. She was diagnosed with infectious spondylitis, and
    Conclusion: This is the first case report of infectious spondylitis caused by
    MeSH term(s) Actinobacteria ; Aged ; Female ; Humans ; Spondylitis/diagnostic imaging ; Spondylitis/drug therapy
    Language English
    Publishing date 2021-08-02
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57080797
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  8. Article ; Online: A case of Slackia exigua bacteremia associated with pyometra in a patient with poor dentition.

    Lim, Kyoung Ree / Son, Jun Seong / Moon, Soo-Youn

    Anaerobe

    2021  Volume 73, Page(s) 102477

    Abstract: We report the first case of Slackia exigua bacteremia related to pyometra. Slackia exigua is an anaerobe that is usually found in the oral cavity and periodontal infections. After two months of treatment with antimicrobial agents, the patient recovered ... ...

    Abstract We report the first case of Slackia exigua bacteremia related to pyometra. Slackia exigua is an anaerobe that is usually found in the oral cavity and periodontal infections. After two months of treatment with antimicrobial agents, the patient recovered from infection.
    MeSH term(s) Actinobacteria ; Bacteremia/diagnosis ; Bacteremia/drug therapy ; Dentition ; Humans ; Pyometra
    Language English
    Publishing date 2021-11-12
    Publishing country England
    Document type Case Reports
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2021.102477
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  9. Article ; Online: The Role of Flavobacterium enshiense R6S-5-6 in the Wetland Ecosystem Revealed by Whole-Genome Analysis.

    Choi, Ahhyeon / Cha, In-Tae / Lee, Ki-Eun / Son, Youn Kyoung / Yu, Jaewoong / Seol, Donghyeok

    Current microbiology

    2023  Volume 80, Issue 2, Page(s) 83

    Abstract: The wetland is an important ecosystem for purifying pollutants and circulating nutrients. Numerous microorganisms contribute to maintaining this function. We obtained Flavobacterium enshiense R6S-5-6 which was isolated from Ungok (Ramsar) Wetland and ... ...

    Abstract The wetland is an important ecosystem for purifying pollutants and circulating nutrients. Numerous microorganisms contribute to maintaining this function. We obtained Flavobacterium enshiense R6S-5-6 which was isolated from Ungok (Ramsar) Wetland and conducted whole-genome sequencing to investigate what contribution R6S-5-6 could make to the wetland community. The complete genome sequence of R6S-5-6 has a size of 3,251,289 bp with 37.68% of GC content. Gene annotation revealed that R6S-5-6 has several pathways to break down pollutants, including denitrification, assimilatory sulfate reduction (ASR), and polyphosphate-accumulating process. Furthermore, R6S-5-6 has genes that can have a positive effect on plants living in wetlands, such as storing essential nutrients, promoting plant growth, and protecting plants against pathogens.
    MeSH term(s) Ecosystem ; Wetlands ; Plant Development ; Environmental Pollutants
    Chemical Substances Environmental Pollutants
    Language English
    Publishing date 2023-01-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 134238-1
    ISSN 1432-0991 ; 0343-8651
    ISSN (online) 1432-0991
    ISSN 0343-8651
    DOI 10.1007/s00284-022-03157-0
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  10. Article ; Online: Genomic insights and comparative analysis of Flavobacterium bizetiae HJ-32-4 isolated from soil.

    Kim, Jisu / Cha, In-Tae / Lee, Ki-Eun / Son, Youn Kyoung / Yu, Jaewoong / Seol, Donghyeok

    Antonie van Leeuwenhoek

    2023  Volume 116, Issue 10, Page(s) 975–986

    Abstract: In the late 1970s, Flavobacterium bizetiae was first isolated from diseased fish in Canada. After four decades of preservation, it was reported as a novel species in 2020. Here, we report the first complete genome sequence of HJ-32-4, a novel strain of F. ...

    Abstract In the late 1970s, Flavobacterium bizetiae was first isolated from diseased fish in Canada. After four decades of preservation, it was reported as a novel species in 2020. Here, we report the first complete genome sequence of HJ-32-4, a novel strain of F. bizetiae. Interestingly, HJ-32-4 was isolated from soil in Gangwon-do, Republic of Korea, unlike the other two previously reported F. bizetiae strains which were isolated from fish. We generated a single circular chromosome of HJ-32-4, comprising 5,745,280 bp with a GC content of 34.2%. The average nucleotide identity (ANI) value of 96.2% indicated that HJ-32-4 belongs to F. bizetiae CIP 105534
    MeSH term(s) Animals ; Flavobacterium/genetics ; Sequence Analysis, DNA ; Soil ; Genomics ; Virulence Factors/genetics ; Fishes ; Phylogeny ; DNA, Bacterial/genetics ; RNA, Ribosomal, 16S/genetics ; Fatty Acids
    Chemical Substances Soil ; Virulence Factors ; DNA, Bacterial ; RNA, Ribosomal, 16S ; Fatty Acids
    Language English
    Publishing date 2023-08-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 214861-4
    ISSN 1572-9699 ; 0003-6072
    ISSN (online) 1572-9699
    ISSN 0003-6072
    DOI 10.1007/s10482-023-01858-5
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