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  1. Book ; Online ; E-Book: Psychiatric and behavioral aspects of epilepsy

    Jones, Nigel C. / Kanner, Andres M.

    current perspectives and mechanisms

    (Current topics in behavioral neurosciences ; volume 55)

    2022  

    Author's details Nigel C. Jones, Andres M. Kanner editors
    Series title Current topics in behavioral neurosciences ; volume 55
    Collection
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (x, 351 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Note Description based on publisher supplied metadata and other sources
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021391991
    ISBN 978-3-031-03235-6 ; 9783031032226 ; 3-031-03235-7 ; 3031032225
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article: Microglial Cells in Epilepsy: Not That Bad After All?

    Jones, Nigel C

    Epilepsy currents

    2020  Volume 21, Issue 1, Page(s) 54–56

    Language English
    Publishing date 2020-12-03
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/1535759720975008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Glial Cell Collaboration in Space and Time Contributes to Epileptogenesis.

    Jones, Nigel C / Ali, Idrish

    Epilepsy currents

    2021  Volume 21, Issue 6, Page(s) 452–454

    Language English
    Publishing date 2021-09-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.1177/15357597211041199
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  4. Article: Thinking Above the Genome: Epigenetic Manipulation as a Disease-Modifying Strategy in Epilepsy.

    Jones, Nigel C

    Epilepsy currents

    2018  Volume 18, Issue 4, Page(s) 255–256

    Language English
    Publishing date 2018-09-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.5698/1535-7597.18.4.255
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  5. Article: Disease-Modification in Epilepsy by Nonpharmacological Methods.

    Jones, Nigel C

    Epilepsy currents

    2018  Volume 18, Issue 1, Page(s) 45–46

    Language English
    Publishing date 2018-05-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.5698/1535-7597.18.1.45
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  6. Article ; Online: Deciphering the code: Identifying true gamma neural oscillations.

    Hudson, Matthew R / Jones, Nigel C

    Experimental neurology

    2022  Volume 357, Page(s) 114205

    Abstract: Neural oscillatory activity occurring in the gamma frequency range (30-80 Hz) has been proposed to play essential roles in sensory and cognitive processing. Supporting this, abnormalities in gamma oscillations have been reported in patients with diverse ... ...

    Abstract Neural oscillatory activity occurring in the gamma frequency range (30-80 Hz) has been proposed to play essential roles in sensory and cognitive processing. Supporting this, abnormalities in gamma oscillations have been reported in patients with diverse neurological and neuropsychiatric disorders in which cognitive impairment is prominent. Understanding the mechanisms underpinning this relationship is the focus of extensive research. But while an increasing number of studies are investigating the intricate relationship between gamma oscillations and cognition, interpretation and generalisation of these studies is limited by the diverse, and at times questionable, methodologies used to analyse oscillatory activity. For example, a variety of different types of gamma oscillatory activity have been characterised, but all are generalised non-specifically as 'gamma oscillations'. This creates confusion, since distinct cellular and network mechanisms are likely responsible for generating these different types of rhythm. Moreover, in some instances, certain analytical measures of electrophysiological data are overinterpreted, with researchers pushing the boundaries of what would be considered rhythmic or oscillatory in nature. Here, we provide clarity on these issues, firstly presenting an overview of the different measures of gamma oscillatory activity, and describing common signal processing techniques used for analysis. Limitations of these techniques are discussed, and recommendations made on how future studies should optimise analyses, presentation and interpretation of gamma frequency oscillations. This is an essential progression in order to harmonise future studies, allowing us to gain a clearer understanding of the role of gamma oscillations in cognition, and in cognitive disorders.
    MeSH term(s) Cognition/physiology ; Cognition Disorders ; Electroencephalography ; Gamma Rhythm ; Humans
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207148-4
    ISSN 1090-2430 ; 0014-4886
    ISSN (online) 1090-2430
    ISSN 0014-4886
    DOI 10.1016/j.expneurol.2022.114205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Potentiating the Strength of Extrasynaptic Currents by Neurosteroid Hormones.

    Jones, Nigel C

    Epilepsy currents

    2016  Volume 16, Issue 4, Page(s) 261–262

    Language English
    Publishing date 2016-07-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2270080-8
    ISSN 1535-7597
    ISSN 1535-7597
    DOI 10.5698/1535-7511-16.4.261
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  8. Article ; Online: Potential Roles for the GluN2D NMDA Receptor Subunit in Schizophrenia.

    Vinnakota, Chitra / Hudson, Matthew R / Jones, Nigel C / Sundram, Suresh / Hill, Rachel A

    International journal of molecular sciences

    2023  Volume 24, Issue 14

    Abstract: ... ...

    Abstract Glutamate
    MeSH term(s) Animals ; Humans ; Mice ; Brain/metabolism ; Interneurons/metabolism ; Mice, Knockout ; Receptors, N-Methyl-D-Aspartate/metabolism ; Schizophrenia/metabolism
    Chemical Substances NR2D NMDA receptor ; Receptors, N-Methyl-D-Aspartate ; Grin2d protein, mouse
    Language English
    Publishing date 2023-07-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241411835
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  9. Article: Network Preservation Analysis Reveals Dysregulated Synaptic Modules and Regulatory Hubs Shared Between Alzheimer's Disease and Temporal Lobe Epilepsy.

    Harutyunyan, Anna / Jones, Nigel C / Kwan, Patrick / Anderson, Alison

    Frontiers in genetics

    2022  Volume 13, Page(s) 821343

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-03-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.821343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Multi-omics integration and epilepsy: Towards a better understanding of biological mechanisms.

    Chong, Debbie / Jones, Nigel C / Schittenhelm, Ralf B / Anderson, Alison / Casillas-Espinosa, Pablo M

    Progress in neurobiology

    2023  Volume 227, Page(s) 102480

    Abstract: The epilepsies are a group of complex neurological disorders characterised by recurrent seizures. Approximately 30% of patients fail to respond to anti-seizure medications, despite the recent introduction of many new drugs. The molecular processes ... ...

    Abstract The epilepsies are a group of complex neurological disorders characterised by recurrent seizures. Approximately 30% of patients fail to respond to anti-seizure medications, despite the recent introduction of many new drugs. The molecular processes underlying epilepsy development are not well understood and this knowledge gap impedes efforts to identify effective targets and develop novel therapies against epilepsy. Omics studies allow a comprehensive characterisation of a class of molecules. Omics-based biomarkers have led to clinically validated diagnostic and prognostic tests for personalised oncology, and more recently for non-cancer diseases. We believe that, in epilepsy, the full potential of multi-omics research is yet to be realised and we envisage that this review will serve as a guide to researchers planning to undertake omics-based mechanistic studies.
    MeSH term(s) Humans ; Proteomics ; Multiomics ; Biomarkers ; Epilepsy/genetics ; Seizures
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-06-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 185535-9
    ISSN 1873-5118 ; 0301-0082
    ISSN (online) 1873-5118
    ISSN 0301-0082
    DOI 10.1016/j.pneurobio.2023.102480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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