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  1. Book ; Online: Data Augmentation for Automated Essay Scoring using Transformer Models

    Gupta, Kshitij

    2022  

    Abstract: Automated essay scoring is one of the most important problem in Natural Language Processing. It has been explored for a number of years, and it remains partially solved. In addition to its economic and educational usefulness, it presents research ... ...

    Abstract Automated essay scoring is one of the most important problem in Natural Language Processing. It has been explored for a number of years, and it remains partially solved. In addition to its economic and educational usefulness, it presents research problems. Transfer learning has proved to be beneficial in NLP. Data augmentation techniques have also helped build state-of-the-art models for automated essay scoring. Many works in the past have attempted to solve this problem by using RNNs, LSTMs, etc. This work examines the transformer models like BERT, RoBERTa, etc. We empirically demonstrate the effectiveness of transformer models and data augmentation for automated essay grading across many topics using a single model.

    Comment: Accepted at ICCMST 2022
    Keywords Computer Science - Computation and Language ; Computer Science - Artificial Intelligence
    Publishing date 2022-10-23
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Total Hip Arthroplasty in Protrusio Acetabuli: A Systematic Review.

    Ansari, Sajid / Gupta, Kshitij / Gupta, Tushar / Raja, Balgovind S / J, Pranav / Kalia, Roop Bhushan

    Hip & pelvis

    2024  Volume 36, Issue 1, Page(s) 12–25

    Abstract: Protrusio acetabuli, or abnormal protrusion of the femoral head into the acetabulum, requires performance of a total hip arthroplasty (THA) for which various reconstruction techniques and outcomes have been described. The aim of this systematic review is ...

    Abstract Protrusio acetabuli, or abnormal protrusion of the femoral head into the acetabulum, requires performance of a total hip arthroplasty (THA) for which various reconstruction techniques and outcomes have been described. The aim of this systematic review is to provide a comprehensive analysis of the current evidence, evaluate treatment efficacy, compare surgical techniques, and identify topics for future research along with improving evidence-based decision-making, improving patient outcomes in the management of this condition. A thorough systematic review of the PubMed, Embase, Cochrane Library databases, and Scopus library was conducted, and articles describing techniques of THA for treatment of protrusion acetabuli were extracted. The initial search generated 751 results. After exclusion, 18 articles were included. Of these, eight were prospective studies and 10 were retrospective. Surgery was performed on 783 hips with a mean age of 60 years; 80% of females who mostly had inflammatory arthritis were followed up for 8.86 years (range, 2-15.4 years). Good outcomes have been achieved with THA using uncemented cups with bone graft; however, no conclusion could be drawn with regard to the femoral side. It can be concluded that the concept of restoration of the anatomical hip center of rotation is paramount for good outcome and better survival of the implant is important when using uncemented cups with a bone graft. In addition, screw augmentation for fixation is not recommended unless absolutely necessary. The most common complications were aseptic loosening and heterotopic ossification. While the former required revision, conservative management was administered for the latter.
    Language English
    Publishing date 2024-02-29
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 3016993-8
    ISSN 2287-3279 ; 2287-3260
    ISSN (online) 2287-3279
    ISSN 2287-3260
    DOI 10.5371/hp.2024.36.1.12
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  3. Article ; Online: Diabetic striatopathy in an adult with ketotic hyperglycaemia.

    Nahid, Eram / Gupta, Saumya / Prasad, Kshitij / Saha, Anish Kumar / Meher, Mukti Prakash / Meena, L P

    The National medical journal of India

    2024  Volume 36, Issue 4, Page(s) 229–230

    Abstract: Diabetic striatopathy (DS) is a rare and life-threatening mani- festation of diabetes. The disease commonly affects individuals of Asian descent, women and the elderly. DS is characterized by dyskinesias with basal ganglia hyperintensities on imaging. ... ...

    Abstract Diabetic striatopathy (DS) is a rare and life-threatening mani- festation of diabetes. The disease commonly affects individuals of Asian descent, women and the elderly. DS is characterized by dyskinesias with basal ganglia hyperintensities on imaging. Despite being rare, prompt recognition of a hyperglycaemia- induced hemichorea-hemiballismus is essential because the symptoms are reversible with correction of hyperglycaemia. Diagnosis is based on blood analysis and neuroimaging findings. Laboratory tests reveal raised glycosylated haemoglobin (HbA1c) levels, which indicate poorly controlled diabetes. Neuroimaging provides suggestive findings of DS. It is usually associated with non-ketotic hyperglycaemia. We report a 50-year-old woman who presented with ketotic hyperglycaemia and left-sided hemichorea and partial seizures with secondary generalization.
    MeSH term(s) Humans ; Female ; Middle Aged ; Hyperglycemia/diagnosis ; Hyperglycemia/complications ; Chorea/etiology ; Chorea/diagnosis ; Dyskinesias/etiology ; Dyskinesias/diagnosis ; Magnetic Resonance Imaging ; Diabetes Complications/diagnosis ; Glycated Hemoglobin/analysis
    Chemical Substances Glycated Hemoglobin
    Language English
    Publishing date 2024-05-01
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 645116-0
    ISSN 2583-150X ; 0970-258X
    ISSN (online) 2583-150X
    ISSN 0970-258X
    DOI 10.25259/NMJI_283_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Teaching NeuroImage: A New Imaging Finding in a Boy With Salla Disease Caused by a Pathogenic Variant in the

    Gupta, Juhi / Reddy, Nihaal / Mankad, Kshitij / Kabra, Utkarsh / Bhandari, Anu / Bagarhatta, Meenu / Gupta, Ashok

    Neurology

    2023  Volume 101, Issue 14, Page(s) 631–632

    MeSH term(s) Child ; Humans ; Male ; Mutation ; Neuroimaging ; Organic Anion Transporters/genetics ; Sialic Acid Storage Disease/diagnostic imaging ; Sialic Acid Storage Disease/genetics ; Symporters/genetics
    Chemical Substances Organic Anion Transporters ; sialic acid transport proteins ; Symporters
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207546
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  5. Article: Comment on O'Shaughnessy et al: 'Management of paediatric humeral shaft fractures and associated nerve palsy'.

    Yasam, Rama Priya / Singh, Vivek / Gupta, Kshitij

    Journal of children's orthopaedics

    2021  Volume 15, Issue 3, Page(s) 304–305

    Language English
    Publishing date 2021-06-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2279410-4
    ISSN 1863-2548 ; 1863-2521
    ISSN (online) 1863-2548
    ISSN 1863-2521
    DOI 10.1302/1863-2548.15.200214
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  6. Article: Can patient anthropometry predict the anterior cruciate ligament footprint dimensions? - An MRI-based observational study on north Indian population.

    Gupta, Kshitij / Choudhury, Arghya Kundu / Raja, Balgovind S / Chandra, Abhishek / Azam, Md Quamar / Kalia, Roop Bhushan

    Journal of clinical orthopaedics and trauma

    2024  Volume 49, Page(s) 102341

    Abstract: Background: Anterior Cruciate Ligament (ACL) reconstruction is one of the most common surgeries being currently done. As we usher into the era of Individualized Anatomic Reconstruction, it is very important to understand the native anatomy of ACL. We ... ...

    Abstract Background: Anterior Cruciate Ligament (ACL) reconstruction is one of the most common surgeries being currently done. As we usher into the era of Individualized Anatomic Reconstruction, it is very important to understand the native anatomy of ACL. We aimed to assess the ACL footprint dimensions in our patients and correlate it with anthropometric variables, which can help in preoperative decision making.
    Method: A total of 143 eligible patients with suspected ACL injury presented during the study period. Out of which 92 were included in the study. Data on patient's age, sex, height, weight and body mass index (BMI) was recorded. The length and area of both the tibial and femoral footprints were measured on MRI. The footprint dimensions were correlated with the recorded anthropometric data.
    Results: The ACL tibial footprint length and area, and femoral footprint length and area were found to be 13.3 ± 2.23 mm, 142.6 ± 26.16 mm
    Conclusions: Height was found to be the most significant predictor of footprint dimensions in our patients. The predictive equations and graphs can aid in preoperative surgical decision making resulting in a more anatomical ACL reconstruction and improve the post-operative results.
    Language English
    Publishing date 2024-01-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 2596956-0
    ISSN 2213-3445 ; 0976-5662
    ISSN (online) 2213-3445
    ISSN 0976-5662
    DOI 10.1016/j.jcot.2024.102341
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  7. Article ; Online: Cellular Delivery of siRNAs Using Bolaamphiphiles.

    Gupta, Kshitij

    Methods in molecular biology (Clifton, N.J.)

    2017  Volume 1632, Page(s) 187–205

    Abstract: Discovery of RNA interference (RNAi) has opened up a new arena of therapeutic intervention for the treatment of cancerous as well as noncancerous diseases. The RNAi pathway utilizes RNAi inducers such as small interfering RNAs (siRNAs) to target and ... ...

    Abstract Discovery of RNA interference (RNAi) has opened up a new arena of therapeutic intervention for the treatment of cancerous as well as noncancerous diseases. The RNAi pathway utilizes RNAi inducers such as small interfering RNAs (siRNAs) to target and silence disease causing genes. However, efficient delivery of siRNAs for eliciting efficacious RNAi has remained a daunting challenge. Nonviral vectors such as lipids have shown great promise in delivering siRNAs. Recently, a novel class of cationic lipid molecules "bolaamphiphile lipids" or "bola lipids" has been shown to deliver siRNAs to cause effective gene silencing in cells. The present chapter showcases the ability of bola lipids to form micelles, bind with nucleic acids and protect nucleic acids against nucleases. Also, high in vitro transfection efficiency for silencing green fluorescent protein (GFP) using Dicer substrate siRNAs (dsiRNAs) designed against GFP at nontoxic dose in a human breast cancer model is demonstrated. Our results showed that these cationic bola lipids are promising siRNA delivery agents.
    MeSH term(s) Cell Line, Tumor ; Cell Survival/genetics ; DNA/chemistry ; DNA/genetics ; Deoxyribonucleases/chemistry ; Furans ; Gene Expression ; Gene Silencing ; Gene Transfer Techniques ; Genes, Reporter ; Humans ; Nucleic Acid Conformation ; Nucleic Acids/chemistry ; Nucleic Acids/genetics ; Pyridones ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/chemistry ; RNA, Small Interfering/genetics ; Transfection/methods
    Chemical Substances Furans ; Nucleic Acids ; Pyridones ; RNA, Small Interfering ; bolaamphiphile ; DNA (9007-49-2) ; Deoxyribonucleases (EC 3.1.-)
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Research Support, N.I.H., Extramural
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-4939-7138-1_12
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  8. Article ; Online: Use of Denosumab and Serial Arterial Embolization Combination Therapy as an Alternative to Surgical Resection in a Case of Large Sacro-Pelvic Giant Cell Tumor.

    Gupta, Kshitij / Jain, Aakash P / Ahuja, Kaustubh / Mittal, Samarth / Kandwal, Pankaj

    Neurology India

    2023  Volume 71, Issue 2, Page(s) 345–348

    MeSH term(s) Humans ; Denosumab/therapeutic use ; Giant Cell Tumors ; Combined Modality Therapy ; Pelvis/pathology ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/surgery ; Neoplasm Recurrence, Local/pathology
    Chemical Substances Denosumab (4EQZ6YO2HI)
    Language English
    Publishing date 2023-05-06
    Publishing country India
    Document type Case Reports ; Letter
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.375422
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    Zs.A 698: Show issues Location:
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  9. Article ; Online: Re-visiting micro ESR as a screening tool for neonatal sepsis.

    Gupta, Kshitij / Bhaskar, Vikram / Narayanan, Anand / Batra, Prerna

    Tropical doctor

    2022  Volume 52, Issue 3, Page(s) 382–385

    Abstract: Our study evaluated the role of micro-erythrocte sedimentation rate (micro-ESR) in the early detection of neonatal sepsis.Neonates with >34 completed weeks of gestation, appropriate for gestational age, admitted in our Neonatal Intensive Care Unit with ... ...

    Abstract Our study evaluated the role of micro-erythrocte sedimentation rate (micro-ESR) in the early detection of neonatal sepsis.Neonates with >34 completed weeks of gestation, appropriate for gestational age, admitted in our Neonatal Intensive Care Unit with clinical suspicion of early onset sepsis were enrolled in the study. A sepsis screen and blood culture was performed on all the babies within 4 h of admission. The sensitivity of micro-ESR for detecting positive blood culture was calculated and the best cut-off was determined using the Area Under Curve.
    MeSH term(s) Blood Sedimentation ; Gestational Age ; Humans ; Infant, Newborn ; Intensive Care Units, Neonatal ; Neonatal Sepsis/diagnosis ; Sepsis/diagnosis
    Language English
    Publishing date 2022-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/00494755221081600
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    Zs.A 1056: Show issues Location:
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  10. Article ; Online: Role of Aspergillus Specific IgG Titres as a Therapeutic Target for Chronic Pulmonary Aspergillosis

    Kshitij Agarwal / Gaurav Bhati / Prateek Gupta / Amit Kumar Verma

    Journal of Clinical and Diagnostic Research, Vol 17, Iss 2, Pp OC01-OC

    A Longitudinal Study

    2023  Volume 04

    Abstract: Introduction: Chronic Pulmonary Aspergillosis (CPA) continues to be an enigma to clinicians in regions with a high prevalence of pulmonary tuberculosis and is often misdiagnosed as the latter, attributable to the significant overlap in symptoms and ... ...

    Abstract Introduction: Chronic Pulmonary Aspergillosis (CPA) continues to be an enigma to clinicians in regions with a high prevalence of pulmonary tuberculosis and is often misdiagnosed as the latter, attributable to the significant overlap in symptoms and radiology. Moreover, although the diagnostic criteria for CPA have been standardised, the role of serological markers in monitoring disease activity and response to therapy is still not well characterised. Aim: To understand the characteristics, risk factors and treatment outcomes in patients developing CPA and to determine the role of serological markers as indicators of disease activity. Materials and Methods: The present longitudinal study was conducted in the Department of Respiratory Medicine, University College of Medical Sciences and its associated Guru Teg Bahadur Hospital, Delhi, India from February 2021 to June 2022. Study included 46 patients suspected of harbouring CPA attributable to their clinico-radiological presentation. The diagnosis of CPA was made using the established criteria. Patients with a confirmed diagnosis of CPA received oral azole antifungals for 6 months and were monitored at 3-monthly intervals for reduction in baseline parameters to determine treatment success/failure. Paired and unpaired parametric variables were compared using the t-test and non parametric methods were compared using the Chi-square test. Results: The diagnosis of CPA was established in 31 (67.4%) patients of whom 77.6% were males and the mean age was 47.3±2.2 years. These patients had been symptomatic for 5.8±1.2 years. Underlying risk factors (such as the history of tuberculosis, chronic obstructive pulmonary disease, diabetes mellitus, history of long-term glucocorticoid use etc.) had been present for 6.9±1.3 years. Patients harboured an average of two risk factors with tuberculosis and diabetes mellitus being the most common local and systemic affliction, respectively. Patients with tuberculosis (p-value=0.001) and chronic steroid use (p-value=0.029) were ...
    Keywords aspergillus fumigatus ; chronic necrotising ; immunoglobulin g antibody ; itraconazole ; pulmonary tuberculosis ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
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