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  1. Article ; Online: Major General Malcolm C. Grow, M.D. (1887-1960) Soldier, Surgeon, Airman.

    Walker, Tyler R / Cowan, Scott W / Yeo, Charles J / Beekley, Alec C

    The American surgeon

    2017  Volume 83, Issue 11, Page(s) 1298–1301

    Abstract: World War I (WWI) and World War II (WWII) both presented physicians with challenges unseen before in history. New inventions such as the machine gun and poisonous gas in WWI and the massive aircraft battles in WWII required physicians and surgeons to ... ...

    Abstract World War I (WWI) and World War II (WWII) both presented physicians with challenges unseen before in history. New inventions such as the machine gun and poisonous gas in WWI and the massive aircraft battles in WWII required physicians and surgeons to adapt and innovate to provide the best care and preventative measures for service members. One physician, Malcolm Cummings Grow, distinguished himself as an innovator, a researcher, and a leader. His contributions to the field of military medicine, flight surgery, and medical administration led to countless lives being saved during the two World Wars and laid the groundwork for many different combat protective equipment still in use today.
    MeSH term(s) Aerospace Medicine/history ; General Surgery/history ; History, 20th Century ; Military Medicine/history ; Personal Protective Equipment/history ; Philadelphia ; United States ; World War I ; World War II
    Language English
    Publishing date 2017-11-01
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portraits
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Re: Long-Term Treatment with OnabotulinumtoxinA Results in Consistent, Durable Improvements in Health Related Quality of Life in Patients with Overactive Bladder: D. A. Ginsberg, M. J. Drake, A. Kaufmann, S. Radomski, A. E. Gousse, C. J. Chermansky, A. Magyar, J. P. Nicandro and V. W. Nitti; 191622-096 Investigators J Urol 2017;198:897-904.

    Walker, Nicholas Faure / Eldred-Evans, David / Sahai, Arun

    The Journal of urology

    2017  Volume 199, Issue 3, Page(s) 856–858

    MeSH term(s) Botulinum Toxins, Type A ; Humans ; Long-Term Care ; Quality of Life ; Urinary Bladder, Overactive ; Urodynamics
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2017-11-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2017.09.144
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  3. Book: M.C.Escher

    Schattschneider, Doris / Escher, Maurits Cornelis / Walker, Wallace

    Kaleidozyklen

    1987  

    Author's details von Doris Schattschneider und Wallace Walker
    Language German
    Size 39 S., 13 Bl., 13 Bl., überw. Ill.
    Publisher TACO
    Publishing place Berlin
    Document type Book
    Note Aus dem Amerikan. übertr. - überw. Bastelbögen
    ISBN 3892680132 ; 9783892680130
    Database Former special subject collection: coastal and deep sea fishing

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  4. Article: The M.R.C.G.P. examination.

    Walker, J H

    Lancet (London, England)

    1979  Volume 2, Issue 8136, Page(s) 251

    MeSH term(s) Canada ; Education, Medical, Graduate ; Educational Measurement ; Family Practice/education ; Professional Competence ; United Kingdom
    Language English
    Publishing date 1979-08-04
    Publishing country England
    Document type Comparative Study ; Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0140-6736 ; 0023-7507
    ISSN (online) 1474-547X
    ISSN 0140-6736 ; 0023-7507
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  5. Article: En réponse à l'article de M.C. Rojat-Habib et al. Intérêt de l'examen extemporané de la limite supérieure d'exérèse des pièces de conisation. Gynécol Obstét Fertil 2000; 28: 518-25.

    Walker, F

    Gynecologie, obstetrique & fertilite

    2001  Volume 28, Issue 12, Page(s) 929–930

    Title translation In response to the article by M.C. Rojat-Habib et al. Usefulness of endocervical margin analysis of conization specimens. Gynéol Obstét Fertil 2000; 28: 518-25 .
    MeSH term(s) Cervix Uteri/pathology ; Conization ; Female ; Humans
    Language French
    Publishing date 2001-01-31
    Publishing country France
    Document type Comment ; Letter
    ZDB-ID 2008222-8
    ISSN 1297-9589
    ISSN 1297-9589
    DOI 10.1016/s1297-9589(00)00043-6
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  6. Article: Comment on: Tassain V, Attal N, Fletcher C, Brasseur L, Dégieux P, Chauvin M, Bouhassira D. Long term effects of oral sustained release morphine on neuropsychological performance in patients with chronic non-malignant pain. Pain 104: 389-400.

    Walker, Jan

    Pain

    2004  Volume 107, Issue 1-2, Page(s) 191; author reply 191–2

    MeSH term(s) Humans ; Morphine/therapeutic use ; Narcotics/therapeutic use ; Pain/drug therapy ; Pain Measurement ; Psychomotor Performance/drug effects ; Time
    Chemical Substances Narcotics ; Morphine (76I7G6D29C)
    Language English
    Publishing date 2004-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 193153-2
    ISSN 1872-6623 ; 0304-3959
    ISSN (online) 1872-6623
    ISSN 0304-3959
    DOI 10.1016/j.pain.2003.09.024
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  7. Article: Establishing the presence of the t(15;17) in suspected acute promyelocytic leukaemia: cytogenetic, molecular and PML immunofluorescence assessment of patients entered into the M.R.C. ATRA trial. M.R.C. Adult Leukaemia Working Party.

    Grimwade, D / Howe, K / Langabeer, S / Davies, L / Oliver, F / Walker, H / Swirsky, D / Wheatley, K / Goldstone, A / Burnett, A / Solomon, E

    British journal of haematology

    1996  Volume 94, Issue 3, Page(s) 557–573

    Abstract: ... of the translocation in 100 patients entered into the Medical Research Council (M.R.C.) ATRA trial. RT-PCR successfully ...

    Abstract Detection of the t(15;17) or its molecular consequence, the PML-RAR alpha rearrangement, is critical for meaningful analysis of clinical trials involving patients with suspected acute promyelocytic leukaemia (APL). Its presence remains the best predictor of a favourable response to retinoids, such as ATRA, which in combination with chemotherapy confer significant improvements in disease-free survival. We have evaluated the relative efficacy of RT-PCR, cytogenetics and PML immunofluorescence staining to identify the existence of the translocation in 100 patients entered into the Medical Research Council (M.R.C.) ATRA trial. RT-PCR successfully identified PML-RAR alpha rearrangements in 93/100 patients, including 65 where only peripheral blood or post-induction marrow samples were available for analysis and in 12 patients in whom cytogenetic assessment failed to demonstrate t(15;17) due to poor-quality metaphases (10/12) or as a reflection of cryptic PML-RAR alpha rearrangements (2/12). Parallel employment of the RAR alpha-PML assay confirmed expression of del(17q)-derived transcripts in 81% and permitted determination of the PML breakpoint (a potential independent prognostic variable) in all 93 cases. Sequencing of RT-PCR products derived from 50 patients with 3' PML breakpoints revealed five bcr 2 cases, including a novel exon 5 breakpoint. 35/81 (43%) patients with cytogenetic evidence of t(15;17) possessed additional karyotypic abnormalities. In four patients with available buffy coat smears, lack of cytogenetic or molecular evidence of the t(15;17) was confirmed by a wild-type PML immunofluorescence nuclear staining pattern, in contrast to the characteristic microparticulate distribution detected in 14 patients with RT-PCR evidence of the rearrangement. However, although PML immunofluorescence staining is suitable for rapid determination of patients likely to benefit from ATRA, this approach does not obviate the need for cytogenetic and RT-PCR analysis of all patients entered into APL clinical trials, because both techniques provide additional information which may prove to be of independent prognostic significance.
    MeSH term(s) Adolescent ; Adult ; Aged ; Amino Acid Sequence ; Base Sequence ; Chromosomes, Human, Pair 15 ; Chromosomes, Human, Pair 17 ; Clinical Trials as Topic ; DNA Primers ; Exons ; Female ; Fluorescent Antibody Technique ; Fusion Proteins, bcr-abl/analysis ; Humans ; Leukemia, Promyelocytic, Acute/diagnosis ; Leukemia, Promyelocytic, Acute/genetics ; Male ; Middle Aged ; Molecular Sequence Data ; Polymerase Chain Reaction ; Prognosis ; Translocation, Genetic
    Chemical Substances DNA Primers ; Fusion Proteins, bcr-abl (EC 2.7.10.2)
    Language English
    Publishing date 1996-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
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  8. Article ; Online: Measurement of the differential cross section for the reaction 2H( gamma,p)n at high photon energies and theta c.m.

    Napolitano / Freedman / Geesaman / Gilman / Green / Holt / Jackson / Kowalczyk / Marchand / Nelson / Zeidman / Beck / Boyd / Collins / Filippone / Jourdan / McKeown / Milner / Potterveld /
    Walker / Woodward / Segel / Tung / Bosted / Kinney / Meziani / Minehart

    Physical review letters

    1988  Volume 61, Issue 22, Page(s) 2530–2533

    Language English
    Publishing date 1988-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.61.2530
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  9. Article ; Online: Evidence for iatrogenic transmission of Alzheimer's disease.

    Jucker, Mathias / Walker, Lary C

    Nature medicine

    2024  Volume 30, Issue 2, Page(s) 344–345

    MeSH term(s) Animals ; Humans ; Alzheimer Disease/etiology ; Amyloid beta-Peptides ; Disease Models, Animal ; Iatrogenic Disease
    Chemical Substances Amyloid beta-Peptides
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02768-9
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  10. Article ; Online: Does dental rehabilitation under general anaesthetic contribute to the development of temporomandibular disorders in children and adolescents? A scoping review.

    Walker, Benjamin M / Donnell, Christopher C

    Journal of oral rehabilitation

    2023  Volume 50, Issue 9, Page(s) 902–913

    Abstract: Background: Temporomandibular disorders (TMDs) have multiple aetiological factors. Although some evidence suggests invasive and lengthy dental procedures may contribute towards TMD development, there is a relative paucity in the literature regarding an ... ...

    Abstract Background: Temporomandibular disorders (TMDs) have multiple aetiological factors. Although some evidence suggests invasive and lengthy dental procedures may contribute towards TMD development, there is a relative paucity in the literature regarding an association between elements of paediatric dental general anaesthesia (pDGA) and TMDs. This review aims to consider the impact of dental rehabilitation (and its constituent elements) performed under general anaesthesia on the development of TMDs in childhood and adolescence and identify theories and/or gaps in knowledge which may benefit from future research.
    Methods: Due to the need to preliminarily examine the nature and extent of the current evidence base, a scoping review approach was chosen. The review was conducted based on the framework provided by the methodological working group of the Joanna Briggs Institute (JBI) for conducting systematic scoping reviews. Electronic databases MEDLINE, Embase, Scopus, Web of Science and Cochrane Library were searched as well as the grey literature using OpenGrey, Nexis, Ethos, Google Scholar and ProQuest, with eligible studies uploaded onto Zotero (Mac Version 5.0.96.2).
    Results: A total of 810 records were identified. After removing duplicates and those not available in English, 260 were identified for title and abstract screening. Seventy-six records underwent full-text review of which only one met the broad inclusion criteria. The most common reasons for exclusion were no specific relation to general anaesthesia, not specifically relating to dental treatment and only being concerned with TMD management. The included study found that while development of TMDs following dental rehabilitation under GA did occur in children, whether the problems caused by treatment were exacerbated by other elements of the pDGA process remains unknown.
    Conclusion: This review has confirmed a distinct paucity of research in this field. While there is no current tangible scientific evidence that common and routine dental procedures lead to TMD, the literature shows that alterations to any one or a combination of critical factors can contribute to TMD development, which may be collectively exacerbated by iatrogenic macrotrauma during the pDGA process. We have highlighted elements of pre-, peri- and post-operative pDGA, alongside biopsychosocial factors, which may contribute to TMD development in childhood and adolescence and may benefit from future research.
    MeSH term(s) Humans ; Child ; Adolescent ; Anesthesia, General/adverse effects ; Anesthesia, General/methods ; Temporomandibular Joint Disorders/etiology ; Temporomandibular Joint Disorders/therapy ; Anesthetics, General
    Chemical Substances Anesthetics, General
    Language English
    Publishing date 2023-06-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 187079-8
    ISSN 1365-2842 ; 0305-182X
    ISSN (online) 1365-2842
    ISSN 0305-182X
    DOI 10.1111/joor.13525
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