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  1. Article ; Online: Correction: The challenges of viral hepatitis elimination: a global response to a global problem.

    Black, Antony P / Wallace, Jack / Binka, Mawuena / Butt, Zahid Ahmad

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 1229

    Language English
    Publishing date 2023-06-28
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-16096-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The challenges of viral hepatitis elimination: a global response to a global problem.

    Black, Antony P / Wallace, Jack / Binka, Mawuena / Butt, Zahid Ahmad

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 1042

    MeSH term(s) Humans ; Hepatitis, Viral, Human/epidemiology ; Hepatitis, Viral, Human/prevention & control ; Global Health ; Antiviral Agents/therapeutic use
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Editorial
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-15960-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The challenges of viral hepatitis elimination

    Antony P. Black / Jack Wallace / Mawuena Binka / Zahid Ahmad Butt

    BMC Public Health, Vol 23, Iss 1, Pp 1-

    a global response to a global problem

    2023  Volume 3

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Correction

    Antony P. Black / Jack Wallace / Mawuena Binka / Zahid Ahmad Butt

    BMC Public Health, Vol 23, Iss 1, Pp 1-

    The challenges of viral hepatitis elimination: a global response to a global problem

    2023  Volume 1

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Risk of major adverse cardiovascular events after SARS-CoV-2 infection in British Columbia: a population-based study.

    Velásquez García, Héctor Alexander / Wong, Stanley / Jeong, Dahn / Binka, Mawuena / Naveed, Zaeema / Wilton, James / Hawkins, Nathaniel Mark / Janjua, Naveed Zafar

    The American journal of medicine

    2024  

    Abstract: Background: COVID-19 is associated with increased risk of post-acute cardiovascular outcomes. Population-based evidence for long periods of observation is still limited.: Methods: This population-based cohort study was conducted using data (2020-2001) ...

    Abstract Background: COVID-19 is associated with increased risk of post-acute cardiovascular outcomes. Population-based evidence for long periods of observation is still limited.
    Methods: This population-based cohort study was conducted using data (2020-2001) from the British Columbia COVID-19 Cohort. The exposure of interest was SARS-CoV-2 infection, identified through reverse transcription-polymerase chain reaction (RT-PCR) assay. Individuals who tested positive (exposed) on RT-PCR were matched to negative controls (unexposed), on sex, age, and RT-PCR collection date, in a 1:4 ratio. Outcomes of interest were incident major adverse cardiovascular events and acute myocardial infarction, identified more than 30 days after RT-PCR collection date. The association between SARS-CoV-2 infection and cardiovascular risk was assessed through multivariable survival models. Population attributable fractions were computed from Cox models.
    Results: WE INCLUDED 649,320 INDIVIDUALS: : 129,864 exposed and 519,456 unexposed. The median duration of follow-up was 260 days; 1,786 events (0·34%) took place among the unexposed, and 702 (0·54%) in the exposed. The risk of major adverse cardiovascular events was higher in the exposed (adjusted HR [aHR]:1·34; 95%CI:1·22-1·46), with greater risk observed in those who were hospitalized (aHR:3·81; 95%CI:3·12-4·65) or required ICU admission (aHR:6·25; 95%CI:4·59-8·52) compared to the unexposed group. The fraction of cardiovascular events attributable to SARS-CoV-2 was 7·04% (95%CI:4·67-9·41%). Comparable results were observed for acute myocardial infarction.
    Conclusions: SARS-CoV-2 infection was associated with higher cardiovascular risk with graded increase across the acute COVID-19 severity, contributing to 7% of incident major adverse cardiovascular events. These findings suggest that long-term monitoring of cardiovascular risk is required in COVID-19 survivors.
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2024.04.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Risk of Severe COVID-19-Related Outcomes among Patients with Cirrhosis: A Population-Based Cohort Study in Canada.

    Velásquez García, Héctor Alexander / Adu, Prince A / Okonkwo-Dappa, Ada / Makuza, Jean Damascene / Cua, Georgine / Binka, Mawuena / Wilton, James / Sbihi, Hind / Janjua, Naveed Z

    Viruses

    2024  Volume 16, Issue 3

    Abstract: We assessed the association between cirrhosis and severe COVID-19-related outcomes among people with laboratory-diagnosed COVID-19 infection in British Columbia, Canada. We used data from the British Columbia (BC) COVID-19 Cohort, a population-based ... ...

    Abstract We assessed the association between cirrhosis and severe COVID-19-related outcomes among people with laboratory-diagnosed COVID-19 infection in British Columbia, Canada. We used data from the British Columbia (BC) COVID-19 Cohort, a population-based cohort that integrates data on all individuals tested for COVID-19, with data on hospitalizations, medical visits, emergency room visits, prescription drugs, chronic conditions, and deaths in the Canadian province of BC. We included all individuals aged ≥18 who tested positive for SARS-CoV-2 by real-time reverse transcription-polymerase chain reaction from 1 January 2021 to 31 December 2021. Multivariable logistic regression models were used to assess the associations of cirrhosis status with COVID-19-related hospitalization and with ICU admission. Of the 162,509 individuals who tested positive for SARS-CoV-2 and were included in the analysis, 768 (0.5%) had cirrhosis. In the multivariable models, cirrhosis was associated with increased odds of hospitalization (aOR = 1.97, 95% CI: 1.58-2.47) and ICU admission (aOR = 3.33, 95% CI: 2.56-4.35). In the analyses stratified by age, we found that the increased odds of ICU admission among people with cirrhosis were present in all the assessed age-groups. Cirrhosis is associated with increased odds of hospitalization and ICU admission among COVID-19 patients.
    MeSH term(s) Humans ; COVID-19/complications ; COVID-19/epidemiology ; SARS-CoV-2 ; Cohort Studies ; Liver Cirrhosis/complications ; Liver Cirrhosis/epidemiology ; British Columbia/epidemiology
    Language English
    Publishing date 2024-02-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16030351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Impact of COVID-19 pandemic on HCV care cascade in Rwanda: Ecological study from July 2019 to June 2021.

    Makuza, Jean Damascene / Jeong, Dahn / Soe, Phyumar / Bartlett, Sofia / Velásquez García, Héctor A / Binka, Mawuena / Adu, Prince / Dushimiyimana, Donatha / Dushimiyimana, Valentine / Maliza, Clarisse / Nisingizwe, Marie Paul / Rwibasira, Gallican / Tuyishime, Albert / Janjua, Naveed Z

    Clinical liver disease

    2022  Volume 20, Issue 1, Page(s) 25–30

    Abstract: Content available: Author Interview and Audio Recording. ...

    Abstract Content available: Author Interview and Audio Recording.
    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2657644-2
    ISSN 2046-2484
    ISSN 2046-2484
    DOI 10.1002/cld.1235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cross-Canada Variability in Blood Donor SARS-CoV-2 Seroprevalence by Social Determinants of Health.

    O'Brien, Sheila F / Caffrey, Niamh / Yi, Qi-Long / Bolotin, Shelly / Janjua, Naveed Z / Binka, Mawuena / Thanh, Caroline Quach / Stein, Derek R / Lang, Amanda / Colquhoun, Amy / Pambrun, Chantale / Reedman, Cassandra N / Drews, Steven J

    Microbiology spectrum

    2023  Volume 11, Issue 1, Page(s) e0335622

    Abstract: We compared the seroprevalence of SARS-CoV-2 anti-nucleocapsid antibodies in blood donors across Canadian regions in 2021. The seroprevalence was the highest in Alberta and the Prairies, and it was so low in Atlantic Canada that few correlates were ... ...

    Abstract We compared the seroprevalence of SARS-CoV-2 anti-nucleocapsid antibodies in blood donors across Canadian regions in 2021. The seroprevalence was the highest in Alberta and the Prairies, and it was so low in Atlantic Canada that few correlates were observed. Being male and of young age were predictive of seropositivity. Racialization was associated with higher seroprevalence in British Columbia and Ontario but not in Alberta and the Prairies. Living in a materially deprived neighborhood predicted higher seroprevalence, but it was more linear across quintiles in Alberta and the Prairies, whereas in British Columbia and Ontario, the most affluent 60% were similarly low and the most deprived 40% similarly elevated. Living in a more socially deprived neighborhood (more single individuals and one parent families) was associated with lower seroprevalence in British Columbia and Ontario but not in Alberta and the Prairies. These data show striking variability in SARS-CoV-2 seroprevalence across regions by social determinants of health.
    MeSH term(s) Adult ; Male ; Humans ; Female ; SARS-CoV-2 ; Blood Donors ; Seroepidemiologic Studies ; Social Determinants of Health ; COVID-19/epidemiology ; Alberta/epidemiology ; Antibodies, Viral
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2023-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03356-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Use of latent class analysis and patient reported outcome measures to identify distinct long COVID phenotypes: A longitudinal cohort study.

    Wong, Alyson W / Tran, Karen C / Binka, Mawuena / Janjua, Naveed Z / Sbihi, Hind / Russell, James A / Carlsten, Christopher / Levin, Adeera / Ryerson, Christopher J

    PloS one

    2023  Volume 18, Issue 6, Page(s) e0286588

    Abstract: Objectives: We sought to 1) identify long COVID phenotypes based on patient reported outcome measures (PROMs) and 2) determine whether the phenotypes were associated with quality of life (QoL) and/or lung function.: Methods: This was a longitudinal ... ...

    Abstract Objectives: We sought to 1) identify long COVID phenotypes based on patient reported outcome measures (PROMs) and 2) determine whether the phenotypes were associated with quality of life (QoL) and/or lung function.
    Methods: This was a longitudinal cohort study of hospitalized and non-hospitalized patients from March 2020 to January 2022 that was conducted across 4 Post-COVID Recovery Clinics in British Columbia, Canada. Latent class analysis was used to identify long COVID phenotypes using baseline PROMs (fatigue, dyspnea, cough, anxiety, depression, and post-traumatic stress disorder). We then explored the association between the phenotypes and QoL (using the EuroQoL 5 dimensions visual analogue scale [EQ5D VAS]) and lung function (using the diffusing capacity of the lung for carbon monoxide [DLCO]).
    Results: There were 1,344 patients enrolled in the study (mean age 51 ±15 years; 780 [58%] were females; 769 (57%) were of a non-White race). Three distinct long COVID phenotypes were identified: Class 1) fatigue and dyspnea, Class 2) anxiety and depression, and Class 3) fatigue, dyspnea, anxiety, and depression. Class 3 had a significantly lower EQ5D VAS at 3 (50±19) and 6 months (54 ± 22) compared to Classes 1 and 2 (p<0.001). The EQ5D VAS significantly improved between 3 and 6 months for Class 1 (median difference of 6.0 [95% CI, 4.0 to 8.0]) and Class 3 (median difference of 5.0 [95% CI, 0 to 8.5]). There were no differences in DLCO between the classes.
    Conclusions: There were 3 distinct long COVID phenotypes with different outcomes in QoL between 3 and 6 months after symptom onset. These phenotypes suggest that long COVID is a heterogeneous condition with distinct subpopulations who may have different outcomes and warrant tailored therapeutic approaches.
    MeSH term(s) Female ; Humans ; Male ; Quality of Life ; Longitudinal Studies ; Post-Acute COVID-19 Syndrome ; Latent Class Analysis ; COVID-19 ; Dyspnea ; Patient Reported Outcome Measures ; Fatigue ; British Columbia
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0286588
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance.

    O'Brien, Sheila F / Reedman, Cassandra N / Osiowy, Carla / Bolotin, Shelly / Yi, Qi-Long / Lourenço, Lillian / Lewin, Antoine / Binka, Mawuena / Caffrey, Niamh / Drews, Steven J

    Viruses

    2023  Volume 15, Issue 2

    Abstract: Hepatitis B surveillance is essential to achieving Canada's goal of eliminating hepatitis B by 2030. Hepatitis B rates, association of infection with vaccine age-eligibility, and risk factors were analyzed among 1,401,603 first-time Canadian blood donors ...

    Abstract Hepatitis B surveillance is essential to achieving Canada's goal of eliminating hepatitis B by 2030. Hepatitis B rates, association of infection with vaccine age-eligibility, and risk factors were analyzed among 1,401,603 first-time Canadian blood donors from 2005 to 2020. Donors were classified as having likely chronic or likely resolved/occult infections based on hepatitis B surface antigen, anti-hepatitis B core antigen, and hepatitis B nucleic acid test results. Likely chronically infected and control donors (ratio 1:4) participated in risk-factor interviews. The 2019 rate of likely chronic infection was 61.9 per 100,000 (95% CI 46.5-80.86) and 1449.5 per 100,000 for likely resolved/occult infections (95% CI 1370.7-1531.7). Likely chronic infections were higher in males (OR 3.2; 95% CI 2.7-3.7) and the vaccine-ineligible birth cohort (OR 1.9; 95% CI 1.6-2.2). The main risk factors were living with someone who had hepatitis (OR 12.5; 95% CI 5.2-30.0) and ethnic origin from a high-prevalence country (OR 8.4; 95% CI 5.9-11.9). Undiagnosed chronic hepatitis B may be more prevalent in Canada than currently determined by traditional passive hepatitis B reporting. Blood donor data can be useful in informing hepatitis B rates and evaluating vaccination programs in Canada.
    MeSH term(s) Male ; Humans ; Blood Donors ; Donor Selection ; Public Health Surveillance ; Canada/epidemiology ; Hepatitis B/diagnosis ; Hepatitis B/epidemiology ; Hepatitis B/prevention & control ; Persistent Infection
    Language English
    Publishing date 2023-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15020409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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