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  1. Article ; Online: Autophagy-related LncRNA PRDM10-DT responds to UVB radiation in keratinocytes.

    Li, Li / Hongying, Chen / Heng, Gu

    Biochemical and biophysical research communications

    2023  Volume 677, Page(s) 105–112

    Abstract: Ultraviolet (UV)-B radiation is a major environmental risk factor that is responsible for the development and progression of many skin disorders. Autophagy is the process of degradation and recycling of damaged cytoplasmic organelles, macromolecular ... ...

    Abstract Ultraviolet (UV)-B radiation is a major environmental risk factor that is responsible for the development and progression of many skin disorders. Autophagy is the process of degradation and recycling of damaged cytoplasmic organelles, macromolecular aggregates, and long-lived proteins. Previously, we found that the autophagy inducer apigenin restored UVB-impaired autophagy and the cellular response by downregulating the expression of autophagy-related genes such as ATG5. To explore long noncoding RNAs (lncRNAs) involved in regulating these autophagy-related genes, in this study, we assessed the expression profiles of lncRNAs and mRNAs using a microarray in human epidermal keratinocytes (HEKs) treated with or without apigenin after UVB radiation. The expression levels of 80 selected autophagy-related genes and related lncRNAs were confirmed by quantitative real-time polymerase chain reaction (qRT‒PCR). The lncRNA PRDM10-DT was proposed to regulate IRGM based on the ceRNA and coexpression pattern and was demonstrated to be involved in autophagy regulation, proliferation and migration of HEKs by qRT‒PCR, Western blotting, colony formation and scratch wound assays, respectively. These findings suggest an autophagy-related lncRNA in response to UVB radiation that promotes the proliferation and migration of HEKs through inducing autophagy by competing microRNAs for IRGM.
    MeSH term(s) Humans ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Apigenin/pharmacology ; Keratinocytes/metabolism ; Epidermis/metabolism ; MicroRNAs/genetics ; Autophagy/genetics ; DNA-Binding Proteins/metabolism ; Transcription Factors/metabolism
    Chemical Substances RNA, Long Noncoding ; Apigenin (7V515PI7F6) ; MicroRNAs ; PRDM10 protein, human ; DNA-Binding Proteins ; Transcription Factors
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.08.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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  2. Article: Water, starch, and nuclear behavior in ray parenchyma during heartwood formation of

    Guo, Pingping / Zhao, Xiping / Yang, Zifei / Wang, Yingxin / Li, Hongying / Zhang, Lepei

    Heliyon

    2024  Volume 10, Issue 5, Page(s) e27231

    Abstract: ... Catalpa ... ...

    Abstract Catalpa bungei
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e27231
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  3. Article: 2-Hydroxy-4-methoxybenzaldehyde, a more effective antifungal aroma than vanillin and its derivatives against

    Li, Qian / Wang, Chong / Xiao, Hongying / Zhang, Yiming / Xie, Yanli

    Frontiers in microbiology

    2024  Volume 15, Page(s) 1359947

    Abstract: ... Fusarium ... ...

    Abstract Fusarium graminearum
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1359947
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  4. Article ; Online: N-glycolylneuraminic acid in red meat and processed meat is a health concern: A review on the formation, health risk, and reduction.

    Liang, Meilian / Wu, Jianping / Li, Hongying / Zhu, Qiujin

    Comprehensive reviews in food science and food safety

    2024  Volume 23, Issue 2, Page(s) e13314

    Abstract: One of the most consistent epidemiological associations between diet and human disease risk is the impact of consuming red meat and processed meat products. In recent years, the health concerns surrounding red meat and processed meat have gained ... ...

    Abstract One of the most consistent epidemiological associations between diet and human disease risk is the impact of consuming red meat and processed meat products. In recent years, the health concerns surrounding red meat and processed meat have gained worldwide attention. The fact that humans have lost the ability to synthesize N-glycolylneuraminic acid (Neu5Gc) makes red meat and processed meat products the most important source of exogenous Neu5Gc for humans. As our research of Neu5Gc has increased, it has been discovered that Neu5Gc in red meat and processed meat is a key factor in many major diseases. Given the objective evidence of the harmful risk caused by Neu5Gc in red meat and processed meat to human health, there is a need for heightened attention in the field of food. This updated review has several Neu5Gc aspects given including biosynthetic pathway of Neu5Gc and its accumulation in the human body, the distribution of Neu5Gc in food, the methods for detecting Neu5Gc, and most importantly, a systematic review of the existing methods for reducing the content of Neu5Gc in red meat and processed meat. It also provides some insights into the current status and future directions in this area.
    MeSH term(s) Humans ; Neuraminic Acids/metabolism ; Meat/analysis ; Red Meat ; Diet
    Chemical Substances N-glycolylneuraminic acid (1113-83-3) ; Neuraminic Acids
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 2185829-9
    ISSN 1541-4337 ; 1541-4337
    ISSN (online) 1541-4337
    ISSN 1541-4337
    DOI 10.1111/1541-4337.13314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Burden of osteoarthritis in China, 1990-2019: findings from the Global Burden of Disease Study 2019.

    Li, Hongying / Kong, Weisi / Liang, Yan / Sun, Huixin

    Clinical rheumatology

    2024  Volume 43, Issue 3, Page(s) 1189–1197

    Abstract: This study aimed to report the most current data on the incidence and disability-adjusted life years (DALY) associated with osteoarthritis in China from 1990 to 2019. Publicly available modelled data from Global Burden of Disease Study (GBD) 2019 were ... ...

    Abstract This study aimed to report the most current data on the incidence and disability-adjusted life years (DALY) associated with osteoarthritis in China from 1990 to 2019. Publicly available modelled data from Global Burden of Disease Study (GBD) 2019 were used. The incidence and DALY, due to osteoarthritis in China, stratified by sex, trends of associated risk factors, assess the age, period, and cohort effects on the long-term trends of osteoarthritis incidence and DALY in China from 1990 to 2019. We found that the age-standardized incidence and DALY rates of osteoarthritis in China are higher than the average levels in Asia, Africa, and Oceania. In 2019, the number of cases of osteoarthritis in China was 10,681,311, an increase of 132.66% compared with 1990. the DALY of osteoarthritis in China was 4,724,885 person-years, which was 159.70% higher than that in 1990. In 2019, the incidence and DALY rates of osteoarthritis in China was 750.96/100,000,332.19/100,000. High body-mass as risk factors for osteoarthritis DALY with the population attributable proportion (PAF) increasing steadily from 1990 to 2019. The incidence and DALY rates of three types of osteoarthritis from high to low are osteoarthritis knee, osteoarthritis hand, and osteoarthritis hip. Age-period-cohort model showed that the incidence rate of osteoarthritis in China shows a trend of increasing first and then decreasing with age; concurrently, the DALY rate of osteoarthritis in China increased with age. For the period effect, we found that the period rate ratio (RR) of osteoarthritis incidence and DALY rates kept increasing in the cohort born before 2005-2009, and then, it was gradually reduced by year of birth in the cohort born after 2005-2009. As for cohort effect, the cohort RR of incidence rate of osteoarthritis almost has no change, while the cohort RR of DALY rate of osteoarthritis kept increasing from 1990 to 2019. The burden and impact of osteoarthritis in China are substantial and are increasing. Adopting suitable control and preventive community measures to reduce modifiable risk factors is needed to reduce the current and future burden of osteoarthritis in China. Key Points • This paper analyzes the disease burden of osteoarthritis in China for the first time and discusses the influence on the disease burden of osteoarthritis from the perspectives of age, period, and cohort.
    MeSH term(s) Humans ; Global Burden of Disease ; Quality-Adjusted Life Years ; Cost of Illness ; China/epidemiology ; Incidence ; Osteoarthritis/epidemiology
    Language English
    Publishing date 2024-01-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-024-06885-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1740: Show issues Location:
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  6. Article ; Online: Well-dispersed Pt/Nb

    Huang, Hongying / Deng, Libo / Zhang, Lei / Zhang, Qianling / Ren, Xiangzhong / Li, Yongliang

    Nanotechnology

    2024  Volume 35, Issue 29

    Abstract: In this work, an advanced hybrid material was constructed by incorporating niobium pentoxide ( ... ...

    Abstract In this work, an advanced hybrid material was constructed by incorporating niobium pentoxide (Nb
    Language English
    Publishing date 2024-04-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ad3c4d
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  7. Article ; Online: Application of the "Hand as Foot" teaching method in explaining appendicitis in children.

    Lei, Xu / Hongying, Li / Rui, Liu

    Asian journal of surgery

    2021  Volume 44, Issue 12, Page(s) 1560–1561

    MeSH term(s) Appendicitis/diagnosis ; Appendicitis/surgery ; Child ; Foot ; Hand ; Humans ; Lower Extremity ; Upper Extremity
    Language English
    Publishing date 2021-09-08
    Publishing country China
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2021.08.032
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    Zs.B 2831: Show issues Location:
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  8. Article ; Online: Segmenting tourists’ motivations via online reviews

    Xin Sun / Zhengyu Wang / Meiyu Zhou / Tianxiong Wang / Hongying Li

    Heliyon, Vol 10, Iss 1, Pp e23539- (2024)

    An exploration of the service strategies for enhancing tourist satisfaction

    1481  

    Abstract: Tourism motivation and satisfaction are classic themes in tourism research. This study combines latent Dirichlet allocation (LDA) and the Censydiam motivation model to analyze online reviews of tourism in Qinghai, China. The aim of this research is to ... ...

    Abstract Tourism motivation and satisfaction are classic themes in tourism research. This study combines latent Dirichlet allocation (LDA) and the Censydiam motivation model to analyze online reviews of tourism in Qinghai, China. The aim of this research is to explore tourist motivation through online reviews and provide innovative service suggestions to improve tourist satisfaction. The LDA model initially extracts six main topics from online comments. Then, using the fuzzy analytic hierarchy process (FAHP), it maps the relationship between topics and tourism motivations to propose strategies for enhancing tourists' enjoyment, conviviality, and other motivating factors. Furthermore, we employ the Kano model to evaluate tourists' satisfaction levels regarding these strategies, demonstrating their positive evaluations. Hence, this study provides tourism industry professionals and service designers with an innovative method for understanding tourists' motivations through online reviews, enabling them to design specific services that enhance tourism experiences.
    Keywords Latent Dirichlet allocation ; Censydiam model ; Online reviews ; Tourism motivation ; Travel experience ; Service design ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 910
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: 2D CeO

    Gong, Haiming / Li, Youji / Li, Hongying / Jin, Zhiliang

    Langmuir : the ACS journal of surfaces and colloids

    2022  Volume 38, Issue 6, Page(s) 2117–2131

    Abstract: Here, an S-scheme heterojunction was constructed on the basis of the modification of a Ni-based metal-organic framework (Ni-MOF) by different in situ treatment strategies. First, ... ...

    Abstract Here, an S-scheme heterojunction was constructed on the basis of the modification of a Ni-based metal-organic framework (Ni-MOF) by different in situ treatment strategies. First, NiS
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.1c03198
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  10. Article ; Online: HMGA1 regulates the mitochondrial apoptosis pathway in sepsis-induced cardiomyopathy.

    Xu, Jing / Li, Xinwei / Lu, Qianqian / Li, Xiaohua / Shan, Hongying

    Cell biochemistry and biophysics

    2024  

    Abstract: High mobility group protein AT-hook 1 (HMGA1), an architectural transcription factor, has previously been reportedto play an essential role in architectural remodeling processes. However, its effects on cardiovascular diseases, particularly sepsis- ... ...

    Abstract High mobility group protein AT-hook 1 (HMGA1), an architectural transcription factor, has previously been reportedto play an essential role in architectural remodeling processes. However, its effects on cardiovascular diseases, particularly sepsis-induced cardiomyopathy, have remained unclear. The study aimed to investigate the role of HMGA1 in lipopolysaccharide-induced cardiomyopathy. Mice subjected to lipopolysaccharide for 12 h resulted in cardiac dysfunction. We used an adeno-associated virus 9 delivery system to achieve cardiac-specific expression of the HMGA1 gene in the mice. H9c2 cardiomyocytes were infected with Ad-HMGA1 to overexpress HMGA1 or transfected with si-HMGA1 to knock down HMGA1. Echocardiography was applied to measure cardiac function. RT-PCR was used to detect the transcriptional level of inflammatory cytokines. CD45 and CD68 immunohistochemical staining were used to detect inflammatory cell infiltration and TUNEL staining to evaluate the cardiomyocyte apoptosis, MitoSox was used to detect mitochondrial reactive oxygen species, JC-1 was used todetect Mitochondrial membrane potential. Our findings revealed that the overexpression of HMGA1 exacerbated myocardial inflammation and apoptosis in response to lipopolysaccharide treatment. Additionally, we also observed that H9c2 cardiomyocytes with HMGA1 overexpression exhibited enhanced inflammation and apoptosis upon stimulation with lipopolysaccharide for 12 h. Conversely, HMGA1 knockdown in H9c2 cardiomyocytes attenuated lipopolysaccharide-induced cardiomyocyte inflammation and apoptosis. Further investigations into the molecular mechanisms underlying these effects showed that HMGA1 promoted lipopolysaccharide-induced mitochondrial-dependent cardiomyocyte apoptosis. The study reveals that HMGA1 worsens myocardial inflammation and apoptosis in response to lipopolysaccharide treatment. Mechanically, HMGA1 exerts its effects by regulating the mitochondria-dependent apoptotic pathway.
    Language English
    Publishing date 2024-03-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1357904-6
    ISSN 1559-0283 ; 1085-9195
    ISSN (online) 1559-0283
    ISSN 1085-9195
    DOI 10.1007/s12013-024-01236-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1498: Show issues Location:
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