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  1. Article: A Game of ColoMonopoly.

    Nakshabendi, Rahman / Kanar, Ozdemir / Agresti, Nicholas / Berry, Andrew C

    ACG case reports journal

    2016  Volume 3, Issue 4, Page(s) e88

    Language English
    Publishing date 2016-07-27
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.2016.61
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Gastrointestinal manifestations of common variable immunodeficiency disease.

    Samuel, Joshua / Agresti, Nicholas / Munoz, Juan

    Endoscopy

    2015  Volume 47 Suppl 1 UCTN, Page(s) E183–4

    MeSH term(s) Adult ; Biopsy ; Capsule Endoscopy ; Common Variable Immunodeficiency/complications ; Diarrhea/etiology ; Endoscopy, Digestive System ; Female ; Hemophilia A/complications ; Humans ; Weight Loss
    Language English
    Publishing date 2015
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0034-1392088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 162: Show issues

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  3. Article: Characteristics of Serrated Adenomas in Non-Hispanic Whites and African Americans Undergoing Screening Colonoscopy.

    Stemboroski, Lauren / Samuel, Joshua / Alkaddour, Ahmad / Agresti, Nicholas / Gupta, Ena / Palacio, Carlos / Munoz, Juan Carlos / Deutch, Amie / Yap, John Erikson L / Vega, Kenneth J

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16200

    Abstract: Background and aim Adenomatous polyps are precursor lesions for colorectal cancer (CRC). Serrated adenomas/polyps are considered a risk factor for the development of proximal and interval CRC. African-Americans are at higher risk for right-sided CRC. ... ...

    Abstract Background and aim Adenomatous polyps are precursor lesions for colorectal cancer (CRC). Serrated adenomas/polyps are considered a risk factor for the development of proximal and interval CRC. African-Americans are at higher risk for right-sided CRC. Minimal data evaluating serrated adenoma characteristics by race/ethnicity on initial screening colonoscopy (SC) exist. The aim of this investigation was to compare the characteristics of serrated adenomas found in non-Hispanic whites (nHw) and African-Americans (AA) undergoing initial SC. Methods The University of Florida-Jacksonville endoscopy database was searched for all SC performed between January 2000 and December 2014. Inclusion criteria were nHw or AA race/ethnicity and histologically proven serrated adenoma found at SC. Data were collected for all included age at SC, sex, number, location, and size of serrated adenomas found. Results A total of 8693 individuals (nHw - 4199 and AA - 4494) underwent SC between January 2000 and December 2014. Serrated adenomas were found in 479 individuals (nHw, n=294; AA, n=185), and AA were significantly less likely than nHw to have serrated adenomas on SC (AA 4.1% vs nHw 7%; p< 0.0001). No difference was observed in mean age, location, or size between nHw and AA with serrated adenomas. Conclusions Serrated adenomas are more frequent in nHw compared to AA at initial SC. No difference was seen in size or location of serrated adenomas, as well as patient age, between AA and nHw. A study of genetic factors predisposing to serrated adenoma formation and the impact of socioeconomic disparities should be performed across ethnic groups to understand this difference.
    Language English
    Publishing date 2021-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Gastrointestinal manifestations of common variable immunodeficiency disease

    Samuel, Joshua / Agresti, Nicholas / Munoz, Juan

    Endoscopy

    2015  Volume 47, Issue S 01, Page(s) E183–E184

    Language English
    Publishing date 2015-01-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0034-1392088
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 162: Show issues

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  5. Article ; Online: Chemotherapy-induced hepatotoxicity.

    Thatishetty, Ameet V / Agresti, Nicholas / O'Brien, Christopher B

    Clinics in liver disease

    2013  Volume 17, Issue 4, Page(s) 671–86, ix–x

    Abstract: Most hepatotoxicity secondary to chemotherapy is idiosyncratic and, therefore, neither dose dependent nor predictable. Some chemotherapy is cleared by the liver and requires dose adjustment in the face of significant liver dysfunction. In addition, ... ...

    Abstract Most hepatotoxicity secondary to chemotherapy is idiosyncratic and, therefore, neither dose dependent nor predictable. Some chemotherapy is cleared by the liver and requires dose adjustment in the face of significant liver dysfunction. In addition, preexisting abnormal liver function has been shown to increase the risk of hepatotoxicity. In addition to typical hepatocellular injury, other presentations, including cholestasis and hepatic sinusoidal obstruction syndrome, also commonly occur. The outcomes can range from asymptomatic liver function test abnormalities, which resolve spontaneously, to cirrhosis, which occurs despite discontinuation of the chemotherapeutic agent.
    MeSH term(s) Antineoplastic Agents/adverse effects ; Chemical and Drug Induced Liver Injury/etiology ; Humans
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2013-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1472315-3
    ISSN 1557-8224 ; 1089-3261
    ISSN (online) 1557-8224
    ISSN 1089-3261
    DOI 10.1016/j.cld.2013.07.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Disruption of CCR5 signaling to treat COVID-19-associated cytokine storm: Case series of four critically ill patients treated with leronlimab.

    Agresti, Nicholas / Lalezari, Jacob P / Amodeo, Phillip P / Mody, Kabir / Mosher, Steven F / Seethamraju, Harish / Kelly, Scott A / Pourhassan, Nader Z / Sudduth, C David / Bovinet, Christopher / ElSharkawi, Ahmed E / Patterson, Bruce K / Stephen, Reejis / Sacha, Jonah B / Wu, Helen L / Gross, Seth A / Dhody, Kush

    Journal of translational autoimmunity

    2021  Volume 4, Page(s) 100083

    Abstract: Coronavirus disease 2019 (COVID-19) is associated with considerable morbidity and mortality. The number of confirmed cases of infection with SARS-CoV-2, the virus causing COVID-19 continues to escalate with over 70 million confirmed cases and over 1.6 ... ...

    Abstract Coronavirus disease 2019 (COVID-19) is associated with considerable morbidity and mortality. The number of confirmed cases of infection with SARS-CoV-2, the virus causing COVID-19 continues to escalate with over 70 million confirmed cases and over 1.6 million confirmed deaths. Severe-to-critical COVID-19 is associated with a dysregulated host immune response to the virus, which is thought to lead to pathogenic immune dysregulation and end-organ damage. Presently few effective treatment options are available to treat COVID-19. Leronlimab is a humanized IgG4, kappa monoclonal antibody that blocks C-C chemokine receptor type 5 (CCR5). It has been shown that in patients with severe COVID-19 treatment with leronlimab reduces elevated plasma IL-6 and chemokine ligand 5 (CCL5), and normalized CD4/CD8 ratios. We administered leronlimab to 4 critically ill COVID-19 patients in intensive care. All 4 of these patients improved clinically as measured by vasopressor support, and discontinuation of hemodialysis and mechanical ventilation. Following administration of leronlimab there was a statistically significant decrease in IL-6 observed in patient A (p=0.034) from day 0-7 and patient D (p=0.027) from day 0-14. This corresponds to restoration of the immune function as measured by CD4+/CD8+ T cell ratio. Although two of the patients went on to survive the other two subsequently died of surgical complications after an initial recovery from SARS-CoV-2 infection.
    Language English
    Publishing date 2021-01-06
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2589-9090
    ISSN (online) 2589-9090
    DOI 10.1016/j.jtauto.2021.100083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Conscious or unconscious: the impact of sedation choice on colon adenoma detection.

    Metwally, Mark / Agresti, Nicholas / Hale, William B / Ciofoaia, Victor / O'Connor, Ryan / Wallace, Michael B / Fine, Jonathan / Wang, Yun / Gross, Seth A

    World journal of gastroenterology

    2011  Volume 17, Issue 34, Page(s) 3912–3915

    Abstract: Aim: To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation.: Methods: This retrospective study was conducted at two separate hospital-based endoscopy units ... ...

    Abstract Aim: To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation.
    Methods: This retrospective study was conducted at two separate hospital-based endoscopy units where approximately 12,000 endoscopic procedures are performed annually, with one endoscopy unit exclusively using anesthesiologist-monitored propofol. Three thousand two hundred and fifty-two patients underwent initial screening or surveillance colonoscopies. Our primary end point was the adenoma detection rate, defined as the number of patients in whom at least one adenoma was found, associated with the type of sedation.
    Results: Three thousand two hundred and fifty-two outpatient colonoscopies were performed by five selected endoscopists. At least one adenoma was detected in 27.6% of patients (95% CI = 26.0-29.1) with no difference in the detection rate between the anesthesiologist-propofol and group and the gastroenterologist-midazolam/fentanyl group (28.1% vs 27.1%, P = 0.53).
    Conclusion: The type of sedation used during colonoscopy does not affect the number of patients in whom adenomatous polyps are detected.
    MeSH term(s) Adenoma/diagnosis ; Adenoma/pathology ; Aged ; Anesthesia ; Choice Behavior ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/pathology ; Colonoscopy/methods ; Conscious Sedation/methods ; Female ; Humans ; Hypnotics and Sedatives/therapeutic use ; Male ; Middle Aged ; Propofol/therapeutic use ; Retrospective Studies
    Chemical Substances Hypnotics and Sedatives ; Propofol (YI7VU623SF)
    Language English
    Publishing date 2011-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v17.i34.3912
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6039: Show issues Location:
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  8. Article ; Online: Conscious or unconscious

    Mark Metwally / Nicholas Agresti / William B Hale / Victor Ciofoaia / Ryan O'Connor / Michael B Wallace / Jonathan Fine / Yun Wang / Seth A Gross

    World Journal of Gastroenterology, Vol 17, Iss 34, Pp 3912-

    The impact of sedation choice on colon adenoma detection

    2011  Volume 3915

    Abstract: AIM: To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation. METHODS: This retrospective study was conducted at two separate hospital-based endoscopy units where ... ...

    Abstract AIM: To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation. METHODS: This retrospective study was conducted at two separate hospital-based endoscopy units where approximately 12 000 endoscopic procedures are performed annually, with one endoscopy unit exclusively using anesthesiologist-monitored propofol. Three thousand two hundred and fifty-two patients underwent initial screening or surveillance colonoscopies. Our primary end point was the adenoma detection rate, defined as the number of patients in whom at least one adenoma was found, associated with the type of sedation. RESULTS: Three thousand two hundred and fifty-two outpatient colonoscopies were performed by five selected endoscopists. At least one adenoma was detected in 27.6% of patients (95% CI = 26.0-29.1) with no difference in the detection rate between the anesthesiologist -propofol and group and the gastroenterologist-midazolam/fentanyl group (28.1% vs 27.1%, P = 0.53). CONCLUSION: The type of sedation used during co-lonoscopy does not affect the number of patients in whom adenomatous polyps are detected.
    Keywords Sedation ; Colonoscopy ; Adenoma ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Baishideng Publishing Group Co., Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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