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  1. Article: Corrigendum: Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids.

    Liao, Danying / Li, Huaibiao

    Frontiers in cell and developmental biology

    2021  Volume 9, Page(s) 684641

    Abstract: This corrects the article DOI: 10.3389/fcell.2020.00419.]. ...

    Abstract [This corrects the article DOI: 10.3389/fcell.2020.00419.].
    Language English
    Publishing date 2021-05-20
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2021.684641
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Corrigendum

    Danying Liao / Huaibiao Li

    Frontiers in Cell and Developmental Biology, Vol

    Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids

    2021  Volume 9

    Keywords lung ; alveolar epithelium ; alveolar type II epithelial cell ; alveolar stem cell ; alveolar organoid ; Wnt pathway ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Cuproptosis-related lncRNAs forecast the prognosis of acute myeloid leukemia.

    Zhang, Tong / Liao, Danying / Hu, Yu

    Translational cancer research

    2023  Volume 12, Issue 5, Page(s) 1175–1195

    Abstract: Background: Acute myeloid leukemia (AML) is a highly heterogeneous cluster of hematologic malignancies. Leukemic stem cells (LSCs) are one of the culprits for the persistence and relapse of AML. The discovery of copper-induced cell death, namely ... ...

    Abstract Background: Acute myeloid leukemia (AML) is a highly heterogeneous cluster of hematologic malignancies. Leukemic stem cells (LSCs) are one of the culprits for the persistence and relapse of AML. The discovery of copper-induced cell death, namely cuproptosis, gives bright insights into the treatment of AML. Analogous to copper ions, long non-coding RNAs (lncRNAs) are not bystanders for AML progression, especially for LSC physiology. Uncovering the involvement of cuproptosis-related lncRNAs in AML will benefit clinical management.
    Methods: Detection of prognostic relevant cuproptosis-related lncRNAs are carried out by Pearson correlation analysis and univariate Cox analysis with RNA sequencing data of The Cancer Genome Atlas-Acute Myeloid Leukemia (TCGA-LAML) cohort. After the least absolute shrinkage and selection operator (LASSO) regression and the subsequent multivariate Cox analysis, a cuproptosis-related risk score (CuRS) system was derived to weigh the risk of AML patients. Thereafter, AML patients were classified into two groups by their risk property which was validated with principal component analysis (PCA), risk curves, Kaplan-Meier survival analysis, the combined receiver operating characteristic (ROC) curves, and nomogram. Variations in biological pathways and divergences in immune infiltration and immune-related processes between groups were resolved by GSEA and CIBERSORT algorism, respectively. Response to chemotherapies were scrutinized as well. The expression profiles of the candidate lncRNAs were examined by real-time quantitative polymerase chain reaction (RT-qPCR) and the specific mechanisms of lncRNA
    Results: We fabricated an efficient prognostic signature named CuRS incorporating 4 lncRNAs (
    Conclusions: The prognostic signature CuRS can guide prognostic stratification and personalized AML therapy. Analysis of
    Language English
    Publishing date 2023-04-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr-22-2526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids.

    Liao, Danying / Li, Huaibiao

    Frontiers in cell and developmental biology

    2020  Volume 8, Page(s) 419

    Keywords covid19
    Language English
    Publishing date 2020-06-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2020.00419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dissecting the Niche for Alveolar Type II Cells With Alveolar Organoids

    Danying Liao / Huaibiao Li

    Frontiers in Cell and Developmental Biology, Vol

    2020  Volume 8

    Keywords lung ; alveolar epithelium ; alveolar type II epithelial cell ; alveolar stem cell ; alveolar organoid ; Wnt pathway ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Deep-MSIM: Fast Image Reconstruction with Deep Learning in Multifocal Structured Illumination Microscopy.

    Liao, Jianhui / Zhang, Chenshuang / Xu, Xiangcong / Zhou, Liangliang / Yu, Bin / Lin, Danying / Li, Jia / Qu, Junle

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 27, Page(s) e2300947

    Abstract: Fast and precise reconstruction algorithm is desired for for multifocal structured illumination microscopy (MSIM) to obtain the super-resolution image. This work proposes a deep convolutional neural network (CNN) to learn a direct mapping from raw MSIM ... ...

    Abstract Fast and precise reconstruction algorithm is desired for for multifocal structured illumination microscopy (MSIM) to obtain the super-resolution image. This work proposes a deep convolutional neural network (CNN) to learn a direct mapping from raw MSIM images to super-resolution image, which takes advantage of the computational advances of deep learning to accelerate the reconstruction. The method is validated on diverse biological structures and in vivo imaging of zebrafish at a depth of 100 µm. The results show that high-quality, super-resolution images can be reconstructed in one-third of the runtime consumed by conventional MSIM method, without compromising spatial resolution. Last but not least, a fourfold reduction in the number of raw images required for reconstruction is achieved by using the same network architecture, yet with different training data.
    Language English
    Publishing date 2023-07-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202300947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Endogenus chondrocytes immobilized by G-CSF in nanoporous gels enable repair of critical-size osteochondral defects.

    Tang, Shangkun / Zhang, Ruinian / Bai, Hanying / Shu, Rui / Chen, Danying / He, Ling / Zhou, Ling / Liao, Zheting / Chen, Mo / Pei, Fuxing / Mao, Jeremy J / Shi, Xiaojun

    Materials today. Bio

    2023  Volume 24, Page(s) 100933

    Abstract: Injured articular cartilage is a leading cause for osteoarthritis. We recently discovered that endogenous stem/progenitor cells not only reside in the superficial zone of mouse articular cartilage, but also regenerated heterotopic bone and ... ...

    Abstract Injured articular cartilage is a leading cause for osteoarthritis. We recently discovered that endogenous stem/progenitor cells not only reside in the superficial zone of mouse articular cartilage, but also regenerated heterotopic bone and cartilage
    Language English
    Publishing date 2023-12-27
    Publishing country England
    Document type Journal Article
    ISSN 2590-0064
    ISSN (online) 2590-0064
    DOI 10.1016/j.mtbio.2023.100933
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Endogenus chondrocytes immobilized by G-CSF in nanoporous gels enable repair of critical-size osteochondral defects

    Shangkun Tang / Ruinian Zhang / Hanying Bai / Rui Shu / Danying Chen / Ling He / Ling Zhou / Zheting Liao / Mo Chen / Fuxing Pei / Jeremy J. Mao / Xiaojun Shi

    Materials Today Bio, Vol 24, Iss , Pp 100933- (2024)

    2024  

    Abstract: Injured articular cartilage is a leading cause for osteoarthritis. We recently discovered that endogenous stem/progenitor cells not only reside in the superficial zone of mouse articular cartilage, but also regenerated heterotopic bone and cartilage in ... ...

    Abstract Injured articular cartilage is a leading cause for osteoarthritis. We recently discovered that endogenous stem/progenitor cells not only reside in the superficial zone of mouse articular cartilage, but also regenerated heterotopic bone and cartilage in vivo. However, whether critical-size osteochondral defects can be repaired by pure induced chemotatic cell homing of these endogenous stem/progenitor cells remains elusive. Here, we first found that cells in the superficial zone of articular cartilage surrounding surgically created 3 × 1 mm defects in explant culture of adult goat and rabbit knee joints migrated into defect-filled fibrin/hylaro1nate gel, and this migration was significantly more robust upon delivery of exogenous granulocyte-colony stimulating factor (G-CSF). Remarkably, G–CSF–recruited chondrogenic progenitor cells (CPCs) showed significantly stronger migration ability than donor-matched chondrocytes and osteoblasts. G–CSF–recruited CPCs robustly differentiated into chondrocytes, modestly into osteoblasts, and barely into adipocytes. In vivo, critical-size osteochondral defects were repaired by G–CSF–recruited endogenous cells postoperatively at 6 and 12 weeks in comparison to poor healing by gel-only group or defect-only group. ICRS and O'Driscoll scores of articular cartilage were significantly higher for both 6- and 12-week G-CSF samples than corresponding gel-only and defect-only groups. Thus, endogenous stem/progenitor cells may be activated by G-CSF, a Food and Drug Administration (FDA)-cleared bone-marrow stimulating factor, to repair osteochondral defects.
    Keywords Osteochondral defects ; Granulocyte-colony stimulating factor ; Chondrogenic progenitor cells ; chondrocyte ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Subject code 616
    Language English
    Publishing date 2024-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Plasma proteomic and metabolomic signatures of B-ALL patients during CAR-T cell therapy.

    Wu, Jianghua / Tang, Lu / Du, Mengyi / Li, Chenggong / Kou, Haiming / Jiang, Huiwen / Luo, Wenjing / Zhang, Yinqiang / Huang, Zhongpei / Liao, Danying / Xiong, Wei / Mei, Heng / Hu, Yu

    Clinical and translational medicine

    2023  Volume 13, Issue 3, Page(s) e1225

    MeSH term(s) Humans ; Receptors, Chimeric Antigen ; Proteomics ; Immunotherapy, Adoptive ; Antigens, CD19 ; Cell- and Tissue-Based Therapy
    Chemical Substances Receptors, Chimeric Antigen ; Antigens, CD19
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2697013-2
    ISSN 2001-1326 ; 2001-1326
    ISSN (online) 2001-1326
    ISSN 2001-1326
    DOI 10.1002/ctm2.1225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Plasma proteomic and metabolomic signatures of B‐ALL patients during CAR‐T cell therapy

    Jianghua Wu / Lu Tang / Mengyi Du / Chenggong Li / Haiming Kou / Huiwen Jiang / Wenjing Luo / Yinqiang Zhang / Zhongpei Huang / Danying Liao / Wei Xiong / Heng Mei / Yu Hu

    Clinical and Translational Medicine, Vol 13, Iss 3, Pp n/a-n/a (2023)

    2023  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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