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Article ; Online: Anticancer properties of colicin E7 against colon cancer

Morovat Taherikalani / Sobhan Ghafourian

Gastroenterology Review, Vol 16, Iss 4, Pp 364-

2021 Volume 368

Keywords	colicin e7 ; colon cancer ; anticancer ; Medicine ; R
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	Termedia Publishing House
Document type	Article ; Online
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Article: Anticancer properties of colicin E7 against colon cancer.

Taherikalani, Morovat / Ghafourian, Sobhan

Przeglad gastroenterologiczny

2021 Volume 16, Issue 4, Page(s) 364–368

Abstract: Introduction: Cancer is a major public health problem in the modern world. Every year, new cases of cancer are diagnosed around the world. Cancer cells are altered cells that have escaped the mechanisms that regulate natural growth. Bacteriocins are ... ...

Abstract	Introduction: Cancer is a major public health problem in the modern world. Every year, new cases of cancer are diagnosed around the world. Cancer cells are altered cells that have escaped the mechanisms that regulate natural growth. Bacteriocins are cationic peptides synthesized by ribosomes that are secreted by almost all groups of bacteria. Some bacteriocins have shown selective toxicity to cancer cells compared to normal cells. This makes them other candidates for research and clinical trials. Aim: Due to the high prevalence of colon cancer and its therapeutic problems, this study was performed on colicin E7 to evaluate its anti-colon cancer properties. Material and methods: For this reason, colE7 was cloned in pet32c vector and purified protein was affected on HT-29 cells to evaluate the expression of p53 and bcl2. Results: Our in silco analysis demonstrated that colicin E7 has 87.23% confidence as anticancer peptide by ACPred-FL program. First, a PCR reaction was performed using specific primers of the colicin E7 gene, which formed the 1728 bp fragment that belongs to this gene. Conclusions: Colicin E7 decreased the expression of bcl2 and increased P53. The results of this study showed the general effect of colicin E7 on cancer cells
Language	English
Publishing date	2021-10-01
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2596134-2
ISSN	1897-4317 ; 1895-5770
ISSN (online)	1897-4317
ISSN	1895-5770
DOI	10.5114/pg.2021.109622
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Article: A five-year systematic review and meta-analysis study on methicillin resistant

Soroush, Setareh / Rezaei, Faranak / Ghanbari, Fatemeh / Halimi, Shahnaz / Taherikalani, Morovat

Iranian journal of microbiology

2023 Volume 15, Issue 1, Page(s) 10–18

Abstract: Background and objectives: One of the most prevalent drug-resistant bacteria is methicillin-resistant : Materials and methods: Published articles on the frequency of MRSE were collected from the Web of Science, PubMed, Scopus, Google Scholar, ... ...

Abstract	Background and objectives: One of the most prevalent drug-resistant bacteria is methicillin-resistant Materials and methods: Published articles on the frequency of MRSE were collected from the Web of Science, PubMed, Scopus, Google Scholar, Cochrane Library, and Iranian databases from the beginning of 2016 to the end of 2020. Of the 503 records identified, 17 studies met the inclusion criteria, and their extracted data were analyzed using comprehensive meta-analysis version 2.0 (Biostat). Results: The analysis showed that the frequency of MRSE has decreased significantly in the last five years and reached 60.8 [95% confidence interval (95% CI) 54.2-66.9] among culture-positive cases of Conclusion: The noticeable reduction in the prevalence of MRSE in Iran could be due to the improvement of infection control programs and interruption of the pathogen transmission cycle. Another influential reason is the significant reduction in methicillin prescriptions by physicians for infections caused by staphylococci.
Language	English
Publishing date	2023-04-13
Publishing country	Iran
Document type	Journal Article ; Review
ZDB-ID	2652849-6
ISSN	2008-4447 ; 2008-3289
ISSN (online)	2008-4447
ISSN	2008-3289
DOI	10.18502/ijm.v15i1.11913
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Article ; Online: Electrospun Nanofibrous Biocomposite of Royal Jelly/Chitosan/Polyvinyl Alcohol (RJ/CS/PVA) Gel as a Biological Dressing for P. aeruginosa-Infected Burn Wound.

Ashrafi, Behnam / Chehelcheraghi, Farzaneh / Rashidipour, Marzieh / Hadavand, Samaneh / Beiranvand, Behrouz / Taherikalani, Morovat / Soroush, Setareh

Applied biochemistry and biotechnology

2023

Abstract: Burn wounds are vulnerable to various infections due to damage to the tissue and changes in immune responses. Pseudomonas aeruginosa is a critical bacterium that can cause burn wound infections, which can be life-threatening and delay wound healing. ... ...

Abstract	Burn wounds are vulnerable to various infections due to damage to the tissue and changes in immune responses. Pseudomonas aeruginosa is a critical bacterium that can cause burn wound infections, which can be life-threatening and delay wound healing. Therefore, it is essential to develop an efficient strategy to prevent the spread of infection in burn wounds. The present study aims to investigate the effectiveness of electrospun nanofibers of royal jelly on a chitosan/polyvinyl alcohol polymer scaffold in repairing burn wounds infected with Pseudomonas aeruginosa. To achieve this, the researchers analyzed the morphology and physicochemical properties of the synthesized nanofibers using SEM, FTIR, BET, and TGA analyses. They also examined the antibacterial properties of the nanofibers using agar diffusion and spread plate techniques. In addition, hemolysis tests were carried out to assess biocompatibility. Finally, the ability of the nanofibers to repair burn wounds infected with Pseudomonas aeruginosa was evaluated using a laboratory mouse model. The study results showed that the synthesized nanofibers had desirable morphology and physicochemical properties and significant antibacterial effects in both in vitro and in vivo conditions. Also, loading RJ into the polymer scaffold significantly reduced erythrocyte lysis. The wound healing and contraction rates were significantly higher than the control groups, and tissue repair, re-epithelialization, and collagen synthesis occurred faster, preventing the spread of infection to deeper tissue areas. Based on these findings, the synthesized system has the potential to serve as a suitable substitute for some invasive treatments and chemical drugs to improve chronic wounds and manage infection control in burn injuries.
Language	English
Publishing date	2023-08-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	392344-7
ISSN	1559-0291 ; 0273-2289
ISSN (online)	1559-0291
ISSN	0273-2289
DOI	10.1007/s12010-023-04701-9
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Article ; Online: Increased of resistant to antibiotics among bacteria caused burn wounds

Morovat Taherikalani

Revista de Epidemiologia e Controle de Infecção, Vol 3, Iss 2, Pp 38-

2013 Volume 39

Keywords	Medicine ; R ; Internal medicine ; RC31-1245 ; Infectious and parasitic diseases ; RC109-216
Language	Portuguese
Publishing date	2013-04-01T00:00:00Z
Publisher	Universidade de Santa Cruz do Sul
Document type	Article ; Online
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Article ; Online: Biosynthesis of titanium dioxide nanoparticles using Hypericum perforatum and Origanum vulgare extracts and their main components, hypericin and carvacrol as promising antibacterial agents.

Khaksarian, Mojtaba / Bahmani, Mahmoud / Taherikalani, Morovat / Ashrafi, Behnam / Rafieian-Kopaei, Mahmoud / Abbasi, Naser

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan

2022 Volume 42, Issue 2, Page(s) 167–175

Abstract: Objective: To evaluate the anti-bacterial activities of titanium dioxide (TiO) nanoparticles of Origanum (O.) vulgare and Hypericum (H.) perforatum extracts, carvacrol and hypericin against Staphylococcus (S.) aureus.: Methods: In this study, ... ...

Abstract	Objective: To evaluate the anti-bacterial activities of titanium dioxide (TiO) nanoparticles of Origanum (O.) vulgare and Hypericum (H.) perforatum extracts, carvacrol and hypericin against Staphylococcus (S.) aureus. Methods: In this study, TiOnanoparticles of O. vulgare and H. perforatum extracts, carvacrol and hypericin, were prepared and their antibacterial effects were evaluated against Staphylococcus (S.) aureus. In this study, scanning electron microscope, fourier transform infrared spectrometer, atomic force microscopy, dynamic light scattering and zeta potential were used to investigate the structure of synthesized drugs. Results: Anti-bacterial activity of synthesized NPs was tested by minimum inhibitory concentration (MIC), minimum bactericidal concentration and disc diffusion method. MICs of TiO-NPs synthesized using O. vulgare, H. perforatum, carvacrol and hypericin and TiO were obtained 250, 62.5, 250, and 250, and 500 μg/mL, respectively. The MBCs for all of these were obtained 1000 μg/mL. Conclusion: Green-synthesized of TiO nanoparticles provides a promising approach to the use of O. vulgare and H. perforatum, carvacrol and hypericin as novel agents and safer antibacterial compounds, especially anti-S. aureus compounds.
MeSH term(s)	Anthracenes ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antineoplastic Agents ; Bacteria ; Cymenes ; Humans ; Hypericum/chemistry ; Nanoparticles ; Origanum/chemistry ; Perylene/analogs & derivatives ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Oils ; Staphylococcus aureus ; Titanium
Chemical Substances	Anthracenes ; Anti-Bacterial Agents ; Antineoplastic Agents ; Cymenes ; Plant Extracts ; Plant Oils ; titanium dioxide (15FIX9V2JP) ; Perylene (5QD5427UN7) ; hypericin (7V2F1075HD) ; carvacrol (9B1J4V995Q) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2022-04-23
Publishing country	China
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603186-9
ISSN	2589-451X ; 0254-6272 ; 0255-2922
ISSN (online)	2589-451X ; 0254-6272
ISSN	0255-2922
DOI	10.19852/j.cnki.jtcm.2022.02.002
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Article ; Online: Encapsulation of

Rashidipour, Marzieh / Ashrafi, Behnam / Nikbakht, Mohammad Reza / Veiskarami, Saeed / Taherikalani, Morovat / Soroush, Setareh

Preparative biochemistry & biotechnology

2021 Volume 51, Issue 10, Page(s) 971–978

Abstract: Satureja khuzistanica ... ...

Abstract	Satureja khuzistanica jamzad
MeSH term(s)	A549 Cells ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacology ; Bacteria/drug effects ; Bacterial Infections/drug therapy ; Chitosan/chemistry ; Drug Carriers/chemistry ; Humans ; Nanoparticles/chemistry ; Neoplasms/drug therapy ; Oils, Volatile/administration & dosage ; Oils, Volatile/chemistry ; Oils, Volatile/pharmacology ; Satureja/chemistry
Chemical Substances	Anti-Bacterial Agents ; Antineoplastic Agents ; Drug Carriers ; Oils, Volatile ; Chitosan (9012-76-4)
Language	English
Publishing date	2021-02-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1322522-4
ISSN	1532-2297 ; 1082-6068
ISSN (online)	1532-2297
ISSN	1082-6068
DOI	10.1080/10826068.2021.1881907
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Article ; Online: Molecular Epidemiology and Recycling of

Ghanbari, Fatemeh / Nourmoradi, Heshmatollah / Nazari, Ali / Sadeghifard, Nourkhoda / Pakzad, Iraj / Soroush, Setareh / Ashrafi, Behnam / Taherikalani, Morovat

Infectious disorders drug targets

2022 Volume 23, Issue 1, Page(s) e280922209259

Abstract: Background: Staphylococcus aureus is a human pathogen causing nosocomial infections and increased hospitalization and mortality among human communities. Methicillin-resistant S. aureus strains are considered a severe threat in nosocomial infections and ... ...

Abstract	Background: Staphylococcus aureus is a human pathogen causing nosocomial infections and increased hospitalization and mortality among human communities. Methicillin-resistant S. aureus strains are considered a severe threat in nosocomial infections and cause complications in the remedy process of bacterial infections. In this study, 137 samples were collected from different departments, staff, and patients in Ilam hospital. Methods: Eighty-eight samples of these strains were examined to test antibiotic resistance and diffusion. MIC (minimum inhibitory concentration) and PCR (polymerase chain reaction) were performed on the samples resistant to oxacillin. 36 (40.9%) strains were MRSA, and 52 (59.1%) isolates were MSSA. 44.4% of MRSA strains with IV SCCmec type. Results: Fourteen different spa types were found using spa typing, of which the most abundant types were t037, t030, and t701, and three new types, including t15471, t15474, and t17470, were identified among the strains. The molecular analysis by MLST showed that the strains are classified into 11 different sequence types. Sequence type 239 and clonal complexes of 329 and 22 were dominant. ST239- spat037-SCCmec III was also identified as the most frequent clone of MRSA. The most identified clones were MRSA ST239-spa t037-SCCmec III. Conclusion: The results show the spa-type distribution between samples of patients, personnel, and surfaces, demonstrating MRSA circulation between patients and the environment. The results show the need to control environmental health.
MeSH term(s)	Humans ; Staphylococcus aureus/genetics ; Molecular Epidemiology ; Methicillin ; Methicillin-Resistant Staphylococcus aureus ; Multilocus Sequence Typing ; Iran/epidemiology ; Staphylococcal Infections/epidemiology ; Staphylococcal Infections/microbiology ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Hospitals, University ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/pharmacology
Chemical Substances	Methicillin (Q91FH1328A) ; Anti-Bacterial Agents
Language	English
Publishing date	2022-09-28
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526522666220928145550
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Article ; Online: Alarming and Threatening Signals from Health Centers About Multi Drug Resistance Staphylococcus haemolyticus.

Maleki, Abbas / Ghafourian, Sobhan / Taherikalani, Morovat / Soroush, Setareh

Infectious disorders drug targets

2018 Volume 19, Issue 2, Page(s) 118–127

Abstract: Objectives: Nowadays, due to the biofilm formation among coagulase-negative staphylococci (CoNS), acquisition of antibiotic resistance and virulence genes could be noted. These organisms resemble other staphylococcus that harbor mecA gene, which encode ... ...

Abstract	Objectives: Nowadays, due to the biofilm formation among coagulase-negative staphylococci (CoNS), acquisition of antibiotic resistance and virulence genes could be noted. These organisms resemble other staphylococcus that harbor mecA gene, which encode methicillin resistance but the diversity in CoNS is higher than other species. Based on increasing antibiotic resistance in Staphylococcus haemolyticus, analyzing of phenotypic and genotypic biofilm formation, antibiotic resistance and genes involved in this process, SCCmec and ACME typing were the aims of the current study. Methods: 256 clinical CoNS isolates were collected that 49 isolates were identified as S. haemolyticus. For evaluation the antibiotic resistance patterns, disk agar diffusion method was applied, and also biofilm assay carried out among methicillin resistant S. haemolyticus and SCCmec and ACME typing. Results: The results of antibiotic susceptibility indicated that the highest resistance was found for cotrimoxazole and erythromycin (86.6%) and the frequency of blaA (96.5%) and msrA (79.3%) genes was much higher than others. Among MRSH isolates 58.6 % showed a weak biofilm phenotype and 41.4% demonstrated a moderate biofilm density. Also, among the biofilm correlated genes, IS 256 (79.31%) was the most frequent. The SCCmec typing of MRSH isolates indicated that the type V was dominant. Conclusion: Our findings indicated that the correlation between high rates of existence Is 256 gene and high prevalence of weak biofilm phenotype was among MRSH isolates. The current study revealed that multiple antibiotic resistance existed in S. haemolyticus isolates that is a warning for public health.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Biofilms ; Child ; DNA, Bacterial/genetics ; Drug Resistance, Multiple, Bacterial/genetics ; Genotype ; Hospitalization ; Hospitals, Pediatric ; Humans ; Iran/epidemiology ; Methicillin/pharmacology ; Microbial Sensitivity Tests ; Polymerase Chain Reaction ; Public Health ; Staphylococcal Infections/microbiology ; Staphylococcus haemolyticus/drug effects ; Staphylococcus haemolyticus/genetics ; Staphylococcus haemolyticus/isolation & purification
Chemical Substances	Anti-Bacterial Agents ; DNA, Bacterial ; Methicillin (Q91FH1328A)
Language	English
Publishing date	2018-09-11
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2234298-9
ISSN	2212-3989 ; 1871-5265
ISSN (online)	2212-3989
ISSN	1871-5265
DOI	10.2174/1871526518666180911142806
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Article: Corrigendum to "Traditional and Modern Cell Culture in Virus Diagnosis"[Osong Public Health Res Perspect 2016;7(2):77-82].

Hematian, Ali / Sadeghifard, Nourkhoda / Mohebi, Reza / Taherikalani, Morovat / Nasrolahi, Abbas / Amraei, Mansour / Ghafourian, Sobhan

Osong public health and research perspectives

2019 Volume 11, Issue 4, Page(s) 266

Abstract: This corrects the article on p. 77 in vol. 7, PMID: 27169004.]. ...

Abstract	[This corrects the article on p. 77 in vol. 7, PMID: 27169004.].
Language	English
Publishing date	2019-06-10
Publishing country	Korea (South)
Document type	Published Erratum
ZDB-ID	2656431-2
ISSN	2233-6052 ; 2210-9099
ISSN (online)	2233-6052
ISSN	2210-9099
DOI	10.24171/j.phrp.2020.11.4.18
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