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  1. Article ; Online: Epigenetics in glaucoma

    Wendy W. Liu / Yang Sun

    The Journal of Clinical Investigation, Vol 133, Iss

    a link between histone methylation and neurodegeneration

    2023  Volume 15

    Keywords Medicine ; R
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher American Society for Clinical Investigation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Epigenetics in glaucoma: a link between histone methylation and neurodegeneration.

    Liu, Wendy W / Sun, Yang

    The Journal of clinical investigation

    2023  Volume 133, Issue 15

    MeSH term(s) Humans ; Histones/genetics ; Histones/metabolism ; Epigenesis, Genetic ; DNA Methylation ; Protein Processing, Post-Translational ; Glaucoma/genetics
    Chemical Substances Histones
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI173784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Epigenetics in glaucoma

    Wendy W. Liu / Yang Sun

    The Journal of Clinical Investigation, Vol 132, Iss

    a link between histone methylation and neurodegeneration

    2023  Volume 21

    Abstract: Normal-tension glaucoma is a form of optic nerve degeneration that is characterized by loss of retinal ganglion cells independent of eye pressure elevation. In this issue of the JCI, Pan et al. report the discovery in a Japanese family of a mutation in ... ...

    Abstract Normal-tension glaucoma is a form of optic nerve degeneration that is characterized by loss of retinal ganglion cells independent of eye pressure elevation. In this issue of the JCI, Pan et al. report the discovery in a Japanese family of a mutation in the METTL23 gene, which encodes a histone arginine methyltransferase that causes normal-pressure glaucoma in haploinsufficiency. Inherited as an autosomal dominant condition, METTL23 deficiency revealed an important function in the regulation of pS2 and the downstream NF-κB signaling pathway, which has previously been linked to glaucomatous optic nerve degeneration. These findings are the first direct link between defective epigenetic regulatory machinery and genetic forms of optic nerve degeneration.
    Keywords Medicine ; R
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher American Society for Clinical Investigation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Methotrexate-Induced Apoptotic Colopathy in Crohn's Disease.

    Chittajallu, Vibhu / Liu, Wendy / Nguyen, Vu

    ACG case reports journal

    2023  Volume 10, Issue 2, Page(s) e00980

    Abstract: Apoptotic colopathy is a pattern of injury not frequently associated with Crohn's disease (CD) despite its association with medications used in CD management. We describe a patient with CD on methotrexate who underwent a diagnostic colonoscopy for ... ...

    Abstract Apoptotic colopathy is a pattern of injury not frequently associated with Crohn's disease (CD) despite its association with medications used in CD management. We describe a patient with CD on methotrexate who underwent a diagnostic colonoscopy for abdominal pain and diarrhea, with biopsies demonstrating apoptotic colopathy. After methotrexate discontinuation, repeat colonoscopy demonstrated resolution of apoptotic colopathy in addition to diarrhea improvement.
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial: Accessible health programs promoting physical activity and fitness level.

    Wang, Ziru / Huang, Wendy Yajun / Liu, Youcheng / Ni, Guoxin

    Frontiers in public health

    2023  Volume 11, Page(s) 1163686

    MeSH term(s) Exercise ; Physical Fitness ; Health Promotion
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1163686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Control by cell size.

    Liu, Wendy F

    Nature materials

    2018  Volume 17, Issue 12, Page(s) 1055–1056

    MeSH term(s) Cell Size ; Macrophages ; Models, Biological
    Language English
    Publishing date 2018-11-23
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2088679-2
    ISSN 1476-4660 ; 1476-1122
    ISSN (online) 1476-4660
    ISSN 1476-1122
    DOI 10.1038/s41563-018-0225-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Epigenetics in glaucoma: a link between histone methylation and neurodegeneration

    Liu, Wendy W / Sun, Yang

    The Journal of clinical investigation

    2022  Volume 132, Issue 21

    Abstract: Normal-tension glaucoma is a form of optic nerve degeneration that is characterized by loss of retinal ganglion cells independent of eye pressure elevation. In this issue of the JCI, Pan et al. report the discovery in a Japanese family of a mutation in ... ...

    Abstract Normal-tension glaucoma is a form of optic nerve degeneration that is characterized by loss of retinal ganglion cells independent of eye pressure elevation. In this issue of the JCI, Pan et al. report the discovery in a Japanese family of a mutation in the METTL23 gene, which encodes a histone arginine methyltransferase that causes normal-pressure glaucoma in haploinsufficiency. Inherited as an autosomal dominant condition, METTL23 deficiency revealed an important function in the regulation of pS2 and the downstream NF-κB signaling pathway, which has previously been linked to glaucomatous optic nerve degeneration. These findings are the first direct link between defective epigenetic regulatory machinery and genetic forms of optic nerve degeneration.
    MeSH term(s) Humans ; DNA Methylation ; Glaucoma/metabolism ; Retinal Ganglion Cells/metabolism ; Nerve Degeneration/pathology ; Epigenesis, Genetic ; Intraocular Pressure
    Language English
    Publishing date 2022-11-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Comment
    ZDB-ID 3067-3
    ISSN 1558-8238 ; 0021-9738
    ISSN (online) 1558-8238
    ISSN 0021-9738
    DOI 10.1172/JCI163670
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.184: Show issues Location:
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  8. Article ; Online: Editorial

    Ziru Wang / Wendy Yajun Huang / Youcheng Liu / Guoxin Ni

    Frontiers in Public Health, Vol

    Accessible health programs promoting physical activity and fitness level

    2023  Volume 11

    Keywords physical activity ; health program ; fitness ; implementation ; influencing factors ; accessibility ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Why prescribe antibiotics? A systematic review of knowledge, tension, and motivation among clinicians in low-, middle- and high-income countries.

    Chan, Olivia S K / Lam, Wendy / Zhao, Shilin / Tun, Hein / Liu, Ping / Wu, Peng

    Social science & medicine (1982)

    2024  Volume 345, Page(s) 116600

    Abstract: Medical professionals such as physicians and veterinarians are responsible for appropriate antimicrobial prescription (AMP) and use. Although seemingly straightforward, the factors influencing antibiotic prescription, a category of antimicrobials, are ... ...

    Abstract Medical professionals such as physicians and veterinarians are responsible for appropriate antimicrobial prescription (AMP) and use. Although seemingly straightforward, the factors influencing antibiotic prescription, a category of antimicrobials, are complex. Many studies have been conducted in the past two decades on this subject. As a result, there is a plethora of empirical evidence regarding the factors influencing clinicians' AMP practices.
    Aim: A systematic review of AMR studies on AMP was conducted, condensing findings according to a combination of the Knowledge, Attitude, and Practice (KAP) and Capacity, Opportunity, Motivation-Behavior (COM-B) models. Review findings were then synthesized and analyzed for policy implementation according to the Consolidated Framework for Implementation Research (CFIR).
    Design and methodology: A systematic literature review was conducted according to PRISMA guidelines to identify peer-reviewed papers indexed in pre-determined medical science, social sciences, and humanities databases that apply the KAP model in their investigations. Antimicrobial prescription factors were compared and contrasted among low- and middle-income countries (LMICs) and high-income countries (HICs).
    Findings: The KAP model is a heuristic and structured framework for identifying and classifying respondents' knowledge. However, other than medical knowledge, factors that influence prescription decision-making can be expanded to include attitudes, perception, personal affinities, professional circumstances, relational pressure, and social norms.
    MeSH term(s) Humans ; Motivation ; Anti-Bacterial Agents/therapeutic use ; Developed Countries ; Physicians ; Income
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-17
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2024.116600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 625: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Urban forests as a strategy for transforming towards healthy cities

    Yin, Shan / Chen, Wendy Y. / Liu, Chunjiang

    Urban Forestry & Urban Greening. 2023 Mar., v. 81 p.127871-

    2023  

    Abstract: Urban forests provide multiple ecosystem services for city dwellers, amongst which improving public health via mitigating mental stresses and providing attractive spaces for diverse physical activities has attracted increasing attention from scholars and ...

    Abstract Urban forests provide multiple ecosystem services for city dwellers, amongst which improving public health via mitigating mental stresses and providing attractive spaces for diverse physical activities has attracted increasing attention from scholars and policy makers within the context of the ongoing COVID-19 pandemic as well as urgently-needed post-pandemic urban transformation towards healthy cities. This short communication summarizes existing empirical evidence pertinent to the linkage between urban forests and public health maintenance and improvement, highlights three underlying mechanisms, i.e., physiological, psychological, and immunological pathways, and outlines practical implications for the establishment and management of urban forests as a strategy for planning healthy cities.
    Keywords COVID-19 infection ; ecosystems ; issues and policy ; public health ; urban forestry ; COVID-19 pandemic ; Healthy cities ; Urban forest
    Language English
    Dates of publication 2023-03
    Publishing place Elsevier GmbH
    Document type Article ; Online
    ISSN 1618-8667
    DOI 10.1016/j.ufug.2023.127871
    Database NAL-Catalogue (AGRICOLA)

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