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  1. Article: Prognostic significance of the pretreatment pan-immune-inflammation value in cancer patients: an updated meta-analysis of 30 studies.

    Hai-Jing, Yu / Shan, Ren / Jie-Qiong, Xia

    Frontiers in nutrition

    2023  Volume 10, Page(s) 1259929

    Abstract: Background: The pan-immune-inflammation value (PIV) has been reported as a promising prognostic biomarker in multiple cancers but still remains inconclusive. The objective of this study is to systematically investigate the association of the ... ...

    Abstract Background: The pan-immune-inflammation value (PIV) has been reported as a promising prognostic biomarker in multiple cancers but still remains inconclusive. The objective of this study is to systematically investigate the association of the pretreatment PIV with survival outcomes in cancer patients, based on available literature.
    Methods: Online databases including PubMed, Embase and the Web of Science were thoroughly searched for studies evaluating the prognostic role of the pretreatment PIV in cancers from the inception to June 2023. Hazard ratios (HRs) with 95% confidence intervals (CIs) were always assessed using a random-effects model. Statistical analyses were performed using Stata 12.0.
    Results: Thirty studies were finally included after comprehensively study searching. In total, 8,799 cancer patients were enrolled in this meta-analysis. The pooled results demonstrated that patients in the high PIV group had a significantly poorer overall survival (HR = 2.07; 95%CI: 1.77-2.41;
    Conclusion: This meta-analysis demonstrated that the pretreatment PIV could be a non-invasive and efficacious prognostic biomarker for cancer patients.
    Language English
    Publishing date 2023-10-02
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2023.1259929
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  2. Article ; Online: Discrete rational and breather solution in the spatial discrete complex modified Korteweg-de Vries equation and continuous counterparts.

    Zhao, Hai-Qiong / Yu, Guo-Fu

    Chaos (Woodbury, N.Y.)

    2017  Volume 27, Issue 4, Page(s) 43113

    Abstract: In this paper, a spatial discrete complex modified Korteweg-de Vries equation is investigated. The Lax pair, conservation laws, Darboux transformations, and breather and rational wave solutions to the semi-discrete system are presented. The distinguished ...

    Abstract In this paper, a spatial discrete complex modified Korteweg-de Vries equation is investigated. The Lax pair, conservation laws, Darboux transformations, and breather and rational wave solutions to the semi-discrete system are presented. The distinguished feature of the model is that the discrete rational solution can possess new W-shape rational periodic-solitary waves that were not reported before. In addition, the first-order rogue waves reach peak amplitudes which are at least three times of the background amplitude, whereas their continuous counterparts are exactly three times the constant background. Finally, the integrability of the discrete system, including Lax pair, conservation laws, Darboux transformations, and explicit solutions, yields the counterparts of the continuous system in the continuum limit.
    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1472677-4
    ISSN 1089-7682 ; 1054-1500
    ISSN (online) 1089-7682
    ISSN 1054-1500
    DOI 10.1063/1.4982204
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  3. Article ; Online: Updating cut-off values of severity scoring systems for community-acquired pneumonia to orchestrate more predictive accuracy.

    Guo, Qi / Li, Hai-Yan / Song, Wei-Dong / Li, Ming / Chen, Xiao-Ke / Liu, Hui / Peng, Hong-Lin / Yu, Hai-Qiong / Liu, Nian / Li, Yan-Hong / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

    Annals of medicine

    2023  Volume 55, Issue 1, Page(s) 2202414

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Aged ; Prospective Studies ; Retrospective Studies ; Pneumonia/diagnosis ; Hypotension ; ROC Curve ; Community-Acquired Infections/diagnosis ; Severity of Illness Index ; Prognosis
    Language English
    Publishing date 2023-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1004226-x
    ISSN 1365-2060 ; 1651-2219 ; 0785-3890 ; 1743-1387
    ISSN (online) 1365-2060 ; 1651-2219
    ISSN 0785-3890 ; 1743-1387
    DOI 10.1080/07853890.2023.2202414
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 680: Show issues Location:
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  4. Article: [Effect of Gegen Qinlian Decoction on cardiac diastolic function of diabetic mice with damp-heat syndrome].

    Yu, Jie-Ying / Lin, Yu-Hao / Zhou, Feng-Hua / Liu, Hai-Qiong / Deng, Guang-Hui / Cheng, Sai-Bo / Wang, Xian-Bao

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2022  Volume 47, Issue 10, Page(s) 2705–2711

    Abstract: This study was designed to explore the effect and mechanism of Gegen Qinlian Decoction(GQD) on cardiac function of diabetic mice with damp-heat syndrome. The db/db diabetic mice were exposed to the damp-heat environment test chamber for inducing the damp- ...

    Abstract This study was designed to explore the effect and mechanism of Gegen Qinlian Decoction(GQD) on cardiac function of diabetic mice with damp-heat syndrome. The db/db diabetic mice were exposed to the damp-heat environment test chamber for inducing the damp-heat syndrome. Forty-eight six-week-old db/db mice were randomly divided into six groups, namely the db/db diabetic model group, db/db diabetic mouse with damp-heat syndrome(db/db-dh) group, db/db diabetic mouse with damp-heat syndrome treated with low-dose GQD(db/db-dh+GQD-L) group, db/db-dh+GQD-M(medium-dose) group, db/db-dh+GQD-H(high-dose) group, and db/db-dh+lipro(liprostatin-1, the inhibitor of ferroptosis) group, with eight six-week-old db/m mice classified into the control group. The results showed that mice presented with the damp-heat syndrome after exposure to the "high-fat diet" and "damp-heat environment", manifested as the elevated fasting blood glucose, reduced food intake, low urine output, diarrhea, listlessness, loose and coarse hair, and dark yellow and lusterless fur. However, the intragastric administration of the high-dose GQD for 10 weeks ameliorated the above-mentioned symptoms, inhibited myocardial hypertrophy and fibrosis, and improved the cardiac diastolic function of db/db-dh mice. qPCR suggested that GQD regulated the expression of ferroptosis-related genes, weakened the lipid peroxidation in the myocardium, and up-regulated glutathione peroxidase 4(GPX4) expression in comparison with those in the db/db-dh group. At the same time, the ferroptosis inhibitor liprostatin-1 significantly improved the cardiac function and reversed the cardiac remodeling of db/db-dh mice. It can be concluded that the damp-heat syndrome may aggravate myocardial ferroptosis and accelerate cardiac remodeling of db/db mice, thus leading to diastolic dysfunction. GQD is able to improve cardiac remodeling and diastolic function in diabetic mice with damp-heat syndrome, which may be related to its inhibition of myocardial ferroptosis.
    MeSH term(s) Animals ; Diabetes Mellitus, Experimental/drug therapy ; Drugs, Chinese Herbal ; Hot Temperature ; Hyperglycemia/drug therapy ; Mice ; Ventricular Remodeling
    Chemical Substances Drugs, Chinese Herbal ; gegenqinlian
    Language Chinese
    Publishing date 2022-06-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20211201.401
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  5. Article ; Online: Complete mitochondrial genome of

    Leng, Meng / Liu, Qiong / Zhao, Hai-Yan / Yu, Xiao-Fei / Yang, Mao-Fa

    Mitochondrial DNA. Part B, Resources

    2023  Volume 8, Issue 2, Page(s) 260–263

    Abstract: ... Gortyna ... ...

    Abstract Gortyna guizhouensis
    Language English
    Publishing date 2023-02-13
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2023.2176183
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  6. Article ; Online: Updating cut-off values of severity scoring systems for community-acquired pneumonia to orchestrate more predictive accuracy

    Qi Guo / Hai-yan Li / Wei-dong Song / Ming Li / Xiao-ke Chen / Hui Liu / Hong-lin Peng / Hai-qiong Yu / Nian Liu / Yan-hong Li / Zhong-dong Lü / Li-hua Liang / Qing-zhou Zhao / Mei Jiang

    Annals of Medicine, Vol 55, Iss

    2023  Volume 1

    Abstract: AbstractBackground: The assessment of severity is crucial in the management of community-acquired pneumonia (CAP). It remains unknown whether updating cut-off values of severity scoring systems orchestrate improvement in predictive accuracy.Methods: 3, ... ...

    Abstract AbstractBackground: The assessment of severity is crucial in the management of community-acquired pneumonia (CAP). It remains unknown whether updating cut-off values of severity scoring systems orchestrate improvement in predictive accuracy.Methods: 3,212 patients with CAP were recruited to two observational prospective cohort studies. Three bettered scoring systems were derived from the corresponding well-established and extensively used pneumonia-specific severity scoring systems, i.e. pneumonia severity index, minor criteria and CURB-65 (confusion, urea >7 mmol/L, respiratory rate ≥30/min, low blood pressure, and age ≥65 years) score, with the updating cut-off values for tachypnea and low blood pressure. Cronbach α was employed to determine construct validity. Discrimination was valued by calculating the area under the receiver operating characteristic curve (AUROC) and net reclassification improvement (NRI).Results: Respiratory rate ≥22/min and systolic blood pressure ≤100 mm Hg were performed better than respiratory rate ≥30/min and hypotension for predicting mortality in the derivation cohort, respectively (AUROC, 0.823 vs 0.519, 0.688 vs 0.622; NRI, 0.61, 0.13). Bettered scoring systems orchestrated higher convergences, indicated by greater Cronbach α and more decrease in Cronbach α if the updating cut-off values were deleted. The six scoring systems agreed well with one another. Bettered- pneumonia severity index, minor criteria and CURB-65 score showed higher associations with severity and mortality rates and demonstrated greater predictive accuracies for mortality compared with the corresponding original systems (AUROC, 0.939 vs 0.883, 0.909 vs 0.871, 0.913 vs 0.859; NRI, 0.113, 0.076, 0.108; respectively). The validation cohort confirmed a similar pattern.Conclusions: Updating cut-off values of severity scoring systems for CAP orchestrate improvement in predictive accuracy, suggesting that it may facilitate the rationalization of clinical triage decision-making and further reduce mortality. The ...
    Keywords Community-acquired pneumonia ; Severity scoring system ; Cut-off value updated ; Mortality ; Medicine ; R
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
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  7. Article ; Online: Author Correction: Prediction of skin disease using a new cytological taxonomy based on cytology and pathology with deep residual learning method.

    Bu, Jin / Lin, Yu / Qing, Li-Qiong / Hu, Gang / Jiang, Pei / Hu, Hai-Feng / Shen, Er-Xia

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 6825

    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-34103-0
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  8. Article ; Online: Retraction Note: Tumor-specific Th2 responses inhibit growth of CT26 colon-cancer cells in mice via converting intratumor regulatory T cells to Th9 cells.

    Liu, Jiang-Qi / Li, Xing-Yong / Yu, Hai-Qiong / Yang, Gui / Liu, Zhi-Qiang / Geng, Xiao-Rui / Wang, Shuai / Mo, Li-Hua / Zeng, Lu / Zhao, Miao / Fu, Yun-Ting / Sun, Hong-Zhi / Liu, Zhi-Gang / Yang, Ping-Chang

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 12950

    Language English
    Publishing date 2021-06-16
    Publishing country England
    Document type Retraction of Publication
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-92334-5
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  9. Article ; Online: qSOFA predicted pneumonia mortality better than minor criteria and worse than CURB-65 with robust elements and higher convergence.

    Guo, Qi / Li, Hai-Yan / Song, Wei-Dong / Liu, Hui / Yu, Hai-Qiong / Li, Yan-Hong / Lü, Zhong-Dong / Liang, Li-Hua / Zhao, Qing-Zhou / Jiang, Mei

    The American journal of emergency medicine

    2021  Volume 52, Page(s) 1–7

    Abstract: Background: Limited data are available on the discriminatory capacity of quick sequential [sepsis-related] organ failure assessment (qSOFA) versus IDSA/ATS minor criteria for predicting mortality in patients with community-acquired pneumonia (CAP).: ... ...

    Abstract Background: Limited data are available on the discriminatory capacity of quick sequential [sepsis-related] organ failure assessment (qSOFA) versus IDSA/ATS minor criteria for predicting mortality in patients with community-acquired pneumonia (CAP).
    Methods: An observational prospective cohort study of 2116 patients with CAP was performed. Construct validity was determined using Cronbach α. Discrimination was assessed using the area under the receiver operating characteristic curve (AUROC) and net reclassification improvement (NRI).
    Results: Overall in-hospital mortality was 6.43%. Mortality was 25.96% for patients with a qSOFA score of 2 or higher versus 3.05% for those with a qSOFA score less than 2 (odds ratio for mortality 6.57, P < 0.0001), and 13.85% for patients with at least 3 minor criteria versus 2.03% for those with 2 or fewer minor criteria (odds ratio for mortality 2.27, P < 0.0001). qSOFA had a higher correlation with mortality than minor criteria, as well as higher internal consistency (Cronbach alpha 0.43 versus 0.14) and diagnostic values of individual elements (larger AUROCs and higher Youden's indices). qSOFA ≥2 was less sensitive but more specific for predicting mortality than ≥3 minor criteria (qSOFA sensitivity 59.6%, specificity 88.3% and positive likelihood ratio 5.11 versus ≥3 minor criteria sensitivity 80.1%, specificity 65.8% and positive likelihood ratio 2.34). The predictive validity of qSOFA was good for mortality (AUROC = 0.868), was statistically greater than minor criteria, was equal to pneumonia severity index, and was inferior compared with CURB-65 (AUROC, 0.824, 0.902, 0.919; NRI, 0.088, -0.068, -0.103; respectively).
    Conclusions: The qSOFA predicted mortality in CAP better than IDSA/ATS minor criteria and worse than CURB-65 with robust elements and higher convergence. qSOFA as a bedside prompt might be positioned as a proxy for minor criteria and increase the recognition and thus merit more appropriate management of CAP patients likely to fare poorly, which might have implications for more accurate clinical triage decisions.
    MeSH term(s) Adult ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/mortality ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Organ Dysfunction Scores ; Pneumonia/complications ; Pneumonia/diagnosis ; Pneumonia/mortality ; Predictive Value of Tests ; Prospective Studies ; Sepsis/diagnosis ; Sepsis/etiology ; Sepsis/mortality
    Language English
    Publishing date 2021-11-24
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2021.11.029
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  10. Article ; Online: Retraction Note

    Jiang-Qi Liu / Xing-Yong Li / Hai-Qiong Yu / Gui Yang / Zhi-Qiang Liu / Xiao-Rui Geng / Shuai Wang / Li-Hua Mo / Lu Zeng / Miao Zhao / Yun-Ting Fu / Hong-Zhi Sun / Zhi-Gang Liu / Ping-Chang Yang

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    Tumor-specific Th2 responses inhibit growth of CT26 colon-cancer cells in mice via converting intratumor regulatory T cells to Th9 cells

    2021  Volume 1

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
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