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Article ; Online: Nursing home caregivers' acceptance of, and experiences with, a new digital intervention for oral healthcare: A qualitative feasibility study.

Lee, Hannah Haewon / Melbye, Elisabeth Lind

2023 Volume 41, Issue 1, Page(s) 68–82

Abstract: Objectives: The objectives of the present study were to qualitatively investigate nursing home caregivers' acceptance of, and experiences with, a new digital intervention for oral healthcare after a period of real-life testing in three nursing homes ... ...

Abstract	Objectives: The objectives of the present study were to qualitatively investigate nursing home caregivers' acceptance of, and experiences with, a new digital intervention for oral healthcare after a period of real-life testing in three nursing homes located in Rogaland county, Norway. Background: Nursing home caregivers report numerous barriers when it comes to provision of adequate oral care for care-dependent older adults. Among the reported barriers are lack of knowledge and skills, care-resistant behaviours, lack of adequate routines and documentation systems for oral health, a high workload, and unclear responsibilities. To overcome these barriers, a digital tool named SmartJournal was developed to assist caregivers in preserving nursing home residents' oral health. Materials and methods: Semistructured interviews were performed with selected caregivers (n = 12) taking part in SmartJournal testing. A theory-driven thematic analysis based on technology acceptance model was conducted. Results: SmartJournal was generally described as a userfriendly and useful tool. The initial reaction of the participants was mixed; some were positive, some had concerns, but many seemed to have a neutral stance to the intervention. Both barriers and facilitating factors for SmartJournal usage were revealed. Interestingly, the usage gradually changed from norm-based to routine-based behaviour during the test period. Although the tool was well-accepted, as demonstrated with study participants' willingness to use it in the future, they had several suggestions for improvements to further adapt it to a nursing home setting. Conclusion: Results from the present study provide valuable information on questions about SmartJournal acceptance and intervention delivery, thereby preparing the ground for a larger scale evaluation study assessing measurable effects of SmartJournal usage in nursing homes.
MeSH term(s)	Humans ; Aged ; Caregivers ; Feasibility Studies ; Nursing Homes ; Delivery of Health Care ; Qualitative Research
Language	English
Publishing date	2023-06-09
Publishing country	England
Document type	Journal Article
ZDB-ID	604810-9
ISSN	1741-2358 ; 0734-0664
ISSN (online)	1741-2358
ISSN	0734-0664
DOI	10.1111/ger.12695
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Article: Effect of perioperative forced air warming blanket on older adult patients undergoing spinal surgery with general anesthesia.

Shin, Youngduck / Lee, Jooyong / Seo, Haewon / Park, Sanghi

Pakistan journal of medical sciences

2024 Volume 40, Issue 4, Page(s) 706–710

Abstract: Objective: As the population of patients aged 65 years and older increases, the number of older adult patients undergoing surgery also increases. Older adults are vulnerable to hypothermia due to age-related changes in the thermoregulatory center, which ...

Abstract	Objective: As the population of patients aged 65 years and older increases, the number of older adult patients undergoing surgery also increases. Older adults are vulnerable to hypothermia due to age-related changes in the thermoregulatory center, which leads to reduced subcutaneous fat tissue, vasomotor response, and heat production. Thus, they are more likely to suffer complications, including cardiovascular changes, blood coagulation disorders, infections, and delayed recovery from surgery. The study investigated the effect of preventive active warming. Methods: This retrospective cohort study conducted at Chungbuk National University Hospital investigated clinical data from older adult patients undergoing spinal surgery from January 1, 2020, to December 13, 2022. In this study, we explored the use of prophylactic active warming during anesthesia induction and post-surgery warming in older adult patients (≥65 years) who experienced hypothermia during and after surgery under general anesthesia. Results: The control group of patients who experienced hypothermia increased from 20% after 10 minutes to 80% after 30 minutes and 100% after 60 minutes. The percentage of patients in the treatment group who initially experienced hypothermia increased from 10% after 30 min to 40% after 60 minutes. However, notably, 90% of these patients had returned to a normal body temperature upon their arrival at the recovery room. The difference in the percentage of patients who developed hypothermia was statistically significant between the two groups. Conclusions: Hypothermia prevention via an air-forced warming blanket was effective for older adult patients undergoing spinal surgery under general anesthesia.
Language	English
Publishing date	2024-03-13
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.40.4.7886
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Article ; Online: Heterologous expression, purification, and characterization of a recombinant Cordyceps militaris lipase from Candida rugosa-like family in Pichia pastoris.

Lee, Juno / Lee, Haewon / Lee, Juchan / Chang, Pahn-Shick

Enzyme and microbial technology

2023 Volume 168, Page(s) 110254

Abstract: Multiple sequence alignments of three lipase isoforms from the filamentous fungus, Cordyceps militaris, have revealed that the deduced protein from their common sequence belongs to the Candida rugosa lipase-like group. To express the protein in its ... ...

Abstract	Multiple sequence alignments of three lipase isoforms from the filamentous fungus, Cordyceps militaris, have revealed that the deduced protein from their common sequence belongs to the Candida rugosa lipase-like group. To express the protein in its active form, recombinant lipase from C. militaris (rCML) was extra cellularly expressed in Pichia pastoris X-33 after removing its signal peptide. Purified rCML was a stable monomeric protein with a molecular mass of 90 kDa, and was highly N-mannosylated compared to the native protein (69 kDa). The catalytic efficiency (k
MeSH term(s)	Lipase/genetics ; Lipase/chemistry ; Cordyceps ; Recombinant Proteins/chemistry ; Pichia/genetics ; Pichia/metabolism ; Triglycerides/metabolism ; Substrate Specificity
Chemical Substances	Lipase (EC 3.1.1.3) ; Recombinant Proteins ; Triglycerides
Language	English
Publishing date	2023-05-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	423729-8
ISSN	1879-0909 ; 0141-0229
ISSN (online)	1879-0909
ISSN	0141-0229
DOI	10.1016/j.enzmictec.2023.110254
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Article: Inappropriate use of intravenous epinephrine leading to atrial fibrillation during prehospital anaphylaxis treatment: A case report.

Jung, Haewon / Ryoo, Hyun Wook / Park, Jungbae / Choi, Seung Hyuk / Lee, Jae Hyuk / Kim, Sujeong

Clinical and experimental emergency medicine

2024

Abstract: In a prehospital setting, the narrow therapeutic window of epinephrine necessitates its cautious administration for anaphylaxis. In this case, a 46-year-old man presented severe anaphylactic symptoms. Following standard protocol, the emergency medical ... ...

Abstract	In a prehospital setting, the narrow therapeutic window of epinephrine necessitates its cautious administration for anaphylaxis. In this case, a 46-year-old man presented severe anaphylactic symptoms. Following standard protocol, the emergency medical technician (EMT) administered intramuscular epinephrine; however, symptoms persisted. Under the oversight of the emergency medical service (EMS) medical director, an additional intravenous bolus of epinephrine was administered, unfortunately leading to atrial fibrillation. This case underscores the potential risks of intravenous epinephrine, which isn't typically recommended for anaphylaxis without continuous monitoring. Since 2019, South Korea has initiated a pilot program to expand the EMT's scope of practice, which gives them the authority to administer epinephrine for anaphylaxis. The ultimate decision regarding epinephrine use for anaphylaxis, emphasizing patient safety, rests with the EMS medical director. Proper training for EMTs, coupled with the EMS medical director's comprehensive knowledge and meticulous protocol adherence, can ensure patient safety and optimal outcomes.
Language	English
Publishing date	2024-01-29
Publishing country	Korea (South)
Document type	Case Reports
ISSN	2383-4625
ISSN	2383-4625
DOI	10.15441/ceem.23.129
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Article ; Online: High-performance Compact Lens-type Energy Analyzer for an Energy Distribution Measurement of a Schottky Electron Source.

Lee, Ha Rim / Hawang, Junhyeok / Ogawa, Takashi / Jung, Haewon / Yun, Dal-Jae / Jisoo, Kim / Lee, Sangsun / Park, In-Yong

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada

2023 Volume 29, Issue Supplement_1, Page(s) 465–466

Language	English
Publishing date	2023-08-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1385710-1
ISSN	1435-8115 ; 1431-9276
ISSN (online)	1435-8115
ISSN	1431-9276
DOI	10.1093/micmic/ozad067.219
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Article ; Online: Multiphase Reset Induced Reliable Dual-Mode Resistance Switching of the Ta/HfO

Shin, Dong Hoon / Park, Hyungjun / Ghenzi, Néstor / Kim, Yeong Rok / Cheong, Sunwoo / Shim, Sung Keun / Yim, Seongpil / Park, Tae Won / Song, Haewon / Lee, Jung Kyu / Kim, Byeong Su / Park, Taegyun / Hwang, Cheol Seong

ACS applied materials & interfaces

2024 Volume 16, Issue 13, Page(s) 16462–16473

Abstract: Higher functionality should be achieved within the device-level switching characteristics to secure the operational possibility of mixed-signal data processing within a memristive crossbar array. This work investigated electroforming-free Ta/ ... ...

Abstract	Higher functionality should be achieved within the device-level switching characteristics to secure the operational possibility of mixed-signal data processing within a memristive crossbar array. This work investigated electroforming-free Ta/HfO
Language	English
Publishing date	2024-03-21
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c19523
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Article ; Online: Pore residues of transient receptor potential channels canonical 1 and 4 heteromer determine channel properties.

Park, Christine Haewon / Kim, Jinsung / Lee, Jung Eun / Kwak, Misun / So, Insuk

American journal of physiology. Cell physiology

2023 Volume 325, Issue 1, Page(s) C42–C51

Abstract: Transient receptor potential channels canonical 1 and 4 (TRPC1 and TRPC4) are proteins belonging to the same TRPC channel family, and the two are known to form a heterotetrameric channel. TRPC4 can form a homotetrameric, nonselective cation channel by ... ...

Abstract	Transient receptor potential channels canonical 1 and 4 (TRPC1 and TRPC4) are proteins belonging to the same TRPC channel family, and the two are known to form a heterotetrameric channel. TRPC4 can form a homotetrameric, nonselective cation channel by itself, but the involvement of the TRPC1 subunit changes several major characteristics of the channel. In this study, we focused on the pore region (selectivity filter, pore helix, and S6 helix) of TRPC1 and TRPC4 as a determinant of the identity and characteristics of a heteromeric TRPC1/4 channel: decreased calcium permeability of the channel and outward-rectifying current-voltage (
MeSH term(s)	Humans ; HEK293 Cells ; Models, Molecular ; Protein Structure, Tertiary ; Calcium/metabolism ; TRPC Cation Channels/chemistry ; Protein Structure, Quaternary ; Protein Multimerization ; Ion Channel Gating ; Cell Membrane/chemistry
Chemical Substances	Calcium (SY7Q814VUP) ; TRPC Cation Channels
Language	English
Publishing date	2023-05-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	392098-7
ISSN	1522-1563 ; 0363-6143
ISSN (online)	1522-1563
ISSN	0363-6143
DOI	10.1152/ajpcell.00488.2022
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Article ; Online: Clinical Characteristics of Gynecologic Problems During Childhood in the Korean Population.

Choi, Haewon / Kim, Sung Eun / Lee, Nae Hyun / Lee, Dong-Yun / Choi, DooSeok

Journal of Korean medical science

2023 Volume 38, Issue 37, Page(s) e279

Abstract: Background: This study analyzed common gynecologic problems among Korean patients younger than ten years.: Methods: We performed a retrospective analysis of medical records of patients younger than ten years who visited the Pediatric and Adolescent ... ...

Abstract	Background: This study analyzed common gynecologic problems among Korean patients younger than ten years. Methods: We performed a retrospective analysis of medical records of patients younger than ten years who visited the Pediatric and Adolescent Gynecology Clinic at Samsung Medical Center between 1995 and 2020. Results: Among the 6,605 patients who visited the Pediatric and Adolescent Gynecology Clinic, data from 642 patients younger than ten years were analyzed in this study. The most common chief complaint was genital anomalies, followed by increased vaginal discharge and abnormal findings on clinical examinations. The most common disease entity was agglutination of the labia minora, which was commonly discovered incidentally during routine screenings. Vulvovaginitis, the second most common disease, was identified by symptoms of vaginal discharge, pruritus, and vaginal spotting. Neoplasm, issues with vaginal bleeding, and "other causes" were additional categories of gynecologic problems. 245 patients (38.2%) were referred from primary care sources, 175 patients (27.4%) sought care directly at the clinic, 169 patients (26.3%) were referrals from the institution's pediatric department, and the remainder were referrals from other departments. Conclusion: This study provides information about the gynecologic problems most frequently encountered in pediatric patients. The study provides helpful insight for primary care physicians into the proper management and timing of referrals for these gynecologic problems of pediatric patients.
MeSH term(s)	Adolescent ; Child ; Female ; Humans ; Ambulatory Care Facilities ; Asian People ; Republic of Korea/epidemiology ; Retrospective Studies ; Uterine Hemorrhage ; Vaginal Discharge/etiology ; Genital Diseases, Female/diagnosis ; Genital Diseases, Female/epidemiology
Language	English
Publishing date	2023-09-18
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	639262-3
ISSN	1598-6357 ; 1011-8934
ISSN (online)	1598-6357
ISSN	1011-8934
DOI	10.3346/jkms.2023.38.e279
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Article: Impact of Comorbid Oppositional Defiant Disorder on the Clinical and Neuropsychological Characteristics of Korean Children With Attention-Deficit/Hyperactivity Disorder.

Kim, Haewon / Jung, Eunji / Lee, Taeyeop / Kim, Seonok / Kim, Hyo-Won

Psychiatry investigation

2023 Volume 20, Issue 10, Page(s) 962–971

Abstract: Objective: The aim of the present study was to investigate the influence of comorbid oppositional defiant disorder (ODD) on clinical features and neuropsychological profiles of children with attention-deficit/hyperactivity disorder (ADHD).: Methods: ... ...

Abstract	Objective: The aim of the present study was to investigate the influence of comorbid oppositional defiant disorder (ODD) on clinical features and neuropsychological profiles of children with attention-deficit/hyperactivity disorder (ADHD). Methods: We divided the participants into three groups: the ADHD with ODD (ADHD/ODD) (n=36), ADHD without ODD (ADHD/noODD) (n=307), and control groups (n=128). Parents of the participants completed the ADHD Rating Scale, Social Responsiveness Scale (SRS), Korean Personality Rating Scale for Children (K-PRC), and 10-item mania scale from the Parent General Behavior Inventory (P-GBI-10M). Neuropsychological profiles were assessed using the Advanced Test of Attention (ATA), Children's Color Trails Test, and Stroop Color and Word Test. Results: The ADHD/ODD group had more ADHD symptoms and functional impairments in relationships with teachers and peers, and self-esteem than the ADHD/noODD group. The ADHD/ODD group scored higher in Social Communication (p<0.001) and Autistic Mannerisms (p<0.001) subscales of SRS, P-GBI-10M (p<0.001), and Delinquency (p<0.001) and Psychosis (p<0.001) subscales of K-PRC than the ADHD/noODD group. Commission Errors (p<0.001) and Response-Time Variability (p<0.001) in Visual ATA and Commission Errors (p<0.001) in Auditory ATA were significantly higher in the ADHD/ODD group than in the ADHD/noODD group. Conclusion: The present study suggests that patients with ADHD with ODD experience more ADHD symptoms and neuropsychological deficits than those with ADHD without ODD. These results also imply that comorbid ODD is associated with greater social impairment and emotional dysregulation.
Language	English
Publishing date	2023-10-24
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2414364-9
ISSN	1976-3026 ; 1738-3684
ISSN (online)	1976-3026
ISSN	1738-3684
DOI	10.30773/pi.2023.0091
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Article: Uterine alveolar rhabdomyosarcoma in an elderly patient manifesting extremely poor prognosis; a rare subtype of rhabdomyosarcoma.

Choi, Haewon / Lee, Hyunji / Kim, Hee Sun / Han, Jung Yeol / Chun, Kyoung-Chul

Obstetrics & gynecology science

2021 Volume 64, Issue 3, Page(s) 336

Language	English
Publishing date	2021-05-13
Publishing country	Korea (South)
Document type	Journal Article ; Published Erratum
ZDB-ID	2814367-X
ISSN	2287-8580 ; 2287-8572
ISSN (online)	2287-8580
ISSN	2287-8572
DOI	10.5468/ogs.20127.e1
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