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Article: J/psi production and nuclear effects for d + Au and p + p collisions at square root of S(NN) = 200 GeV.

Adler, S S / Afanasiev, S / Aidala, C / Ajitanand, N N / Akiba, Y / Al-Jamel, A / Alexander, J / Aoki, K / Aphecetche, L / Armendariz, R / Aronson, S H / Atomssa, E T / Averbeck, R / Awes, T C / Babintsev, V / Baldisseri, A / Barish, K N / Barnes, P D / Bassalleck, B /

Bathe, S / Batsouli, S / Baublis, V / Bauer, F / Bazilevsky, A / Belikov, S / Bjorndal, M T / Boissevain, J G / Borel, H / Brooks, M L / Brown, D S / Bruner, N / Bucher, D / Buesching, H / Bumazhnov, V / Bunce, G / Burward-Hoy, J M / Butsyk, S / Camard, X / Chand, P / Chang, W C / Chernichenko, S / Chi, C Y / Chiba, J / Chiu, M / Choi, I J / Choudhury, R K / Chujo, T / Cianciolo, V / Cobigo, Y / Cole, B A / Comets, M P / Constantin, P / Csanád, M / Csörgo, T / Cussonneau, J P / d'Enterria, D / Das, K / David, G / Deák, F / Delagrange, H / Denisov, A / Deshpande, A / Desmond, E J / Devismes, A / Dietzsch, O / Drachenberg, J L / Drapier, O / Drees, A / Durum, A / Dutta, D / Dzhordzhadze, V / Efremenko, Y V / En'yo, H / Espagnon, B / Esumi, S / Fields, D E / Finck, C / Fleuret, F / Fokin, S L / Fox, B D / Fraenkel, Z / Frantz, J E / Franz, A / Frawley, A D / Fukao, Y / Fung, S-Y / Gadrat, S / Germain, M / Glenn, A / Gonin, M / Gosset, J / Goto, Y / Granier de Cassagnac, R / Grau, N / Greene, S V / Grosse Perdekamp, M / Gustafsson, H-A / Hachiya, T / Haggerty, J S / Hamagaki, H / Hansen, A G / Hartouni, E P / Harvey, M / Hasuko, K / Hayano, R / He, X / Heffner, M / Hemmick, T K / Heuser, J M / Hidas, P / Hiejima, H / Hill, J C / Hobbs, R / Holzmann, W / Homma, K / Hong, B / Hoover, A / Horaguchi, T / Ichihara, T / Ikonnikov, V V / Imai, K / Inaba, M / Inuzuka, M / Isenhower, D / Isenhower, L / Ishihara, M / Issah, M / Isupov, A / Jacak, B V / Jia, J / Jinnouchi, O / Johnson, B M / Johnson, S C / Joo, K S / Jouan, D / Kajihara, F / Kametani, S / Kamihara, N / Kaneta, M / Kang, J H / Katou, K / Kawabata, T / Kazantsev, A V / Kelly, S / Khachaturov, B / Khanzadeev, A / Kikuchi, J / Kim, D J / Kim, E / Kim, G-B / Kim, H J / Kinney, E / Kiss, A / Kistenev, E / Kiyomichi, A / Klein-Boesing, C / Kobayashi, H / Kochenda, L / Kochetkov, V / Kohara, R / Komkov, B / Konno, M / Kotchetkov, D / Kozlov, A / Kroon, P J / Kuberg, C H / Kunde, G J / Kurita, K / Kweon, M J / Kwon, Y / Kyle, G S / Lacey, R / Lajoie, J G / Le Bornec, Y / Lebedev, A / Leckey, S / Lee, D M / Leitch, M J / Leite, M A L / Li, X H / Lim, H / Litvinenko, A / Liu, M X / Maguire, C F / Makdisi, Y I / Malakhov, A / Manko, V I / Mao, Y / Martinez, G / Masui, H / Matathias, F / Matsumoto, T / McCain, M C / McGaughey, P L / Miake, Y / Miller, T E / Milov, A / Mioduszewski, S / Mishra, G C / Mitchell, J T / Mohanty, A K / Morrison, D P / Moss, J M / Mukhopadhyay, D / Muniruzzaman, M / Nagamiya, S / Nagle, J L / Nakamura, T / Newby, J / Nyanin, A S / Nystrand, J / O'brien, E / Ogilvie, C A / Ohnishi, H / Ojha, I D / Okada, H / Okada, K / Oskarsson, A / Otterlund, I / Oyama, K / Ozawa, K / Pal, D / Palounek, A P T / Pantuev, V / Papavassiliou, V / Park, J / Park, W J / Pate, S F / Pei, H / Penev, V / Peng, J-C / Pereira, H / Peresedov, V / Pierson, A / Pinkenburg, C / Pisani, R P / Purschke, M L / Purwar, A K / Qualls, J M / Rak, J / Ravinovich, I / Read, K F / Reuter, M / Reygers, K / Riabov, V / Riabov, Y / Roche, G / Romana, A / Rosati, M / Rosendahl, S S E / Rosnet, P / Rykov, V L / Ryu, S S / Saito, N / Sakaguchi, T / Sakai, S / Samsonov, V / Sanfratello, L / Santo, R / Sato, H D / Sato, S / Sawada, S / Schutz, Y / Semenov, V / Seto, R / Shea, T K / Shein, I / Shibata, T-A / Shigaki, K / Shimomura, M / Sickles, A / Silva, C L / Silvermyr, D / Sim, K S / Soldatov, A / Soltz, R A / Sondheim, W E / Sorensen, S P / Sourikova, I V / Staley, F / Stankus, P W / Stenlund, E / Stepanov, M / Ster, A / Stoll, S P / Sugitate, T / Sullivan, J P / Takagi, S / Takagui, E M / Taketani, A / Tanaka, K H / Tanaka, Y / Tanida, K / Tannenbaum, M J / Taranenko, A / Tarján, P / Thomas, T L / Togawa, M / Tojo, J / Torii, H / Towell, R S / Tram, V-N / Tserruya, I / Tsuchimoto, Y / Tydesjö, H / Tyurin, N / Uam, T J / van Hecke, H W / Velkovska, J / Velkovsky, M / Veszprémi, V / Vinogradov, A A / Volkov, M A / Vznuzdaev, E / Wang, X R / Watanabe, Y / White, S N / Willis, N / Wohn, F K / Woody, C L / Xie, W / Yanovich, A / Yokkaichi, S / Young, G R / Yushmanov, I E / Zajc, W A / Zhang, C / Zhou, S / Zimányi, J / Zolin, L / Zong, X

Physical review letters

2006 Volume 96, Issue 1, Page(s) 12304

Abstract: J/psi production in d + Au and p + p collisions at square root of S(NN) = 200 GeV has been measured ... by the PHENIX experiment at rapidities -2.2 < y < +2.4. The cross sections and nuclear dependence of J/psi ... production versus rapidity, transverse momentum, and centrality are obtained and compared to lower energy p ...

Abstract	J/psi production in d + Au and p + p collisions at square root of S(NN) = 200 GeV has been measured by the PHENIX experiment at rapidities -2.2 < y < +2.4. The cross sections and nuclear dependence of J/psi production versus rapidity, transverse momentum, and centrality are obtained and compared to lower energy p + A results and to theoretical models. The observed nuclear dependence in d + Au collisions is found to be modest, suggesting that the absorption in the final state is weak and the shadowing of the gluon distributions is small and consistent with Dokshitzer-Gribov-Lipatov-Altarelli-Parisi-based parametrizations that fit deep-inelastic scattering and Drell-Yan data at lower energies.
Language	English
Publishing date	2006-01-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.96.012304
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Book ; Online ; E-Book: Basic Monitoring in Canine and Feline Emergency Patients

Brooks, Aimee C. / Johnson, P. A. / Thomovsky, Elizabeth J.

2020

Abstract: This book discusses the various basic monitoring techniques available for emergency patients. The book elaborates on and explains monitoring techniques that can be easily performed in basic ER clinics and primary care clinics."-- Provided by publisher. ...

Author's details	edited by Elizabeth J. Thomovsky, P.A. Johnson, Aimee C. Brooks
Abstract	"This book discusses the various basic monitoring techniques available for emergency patients. The book elaborates on and explains monitoring techniques that can be easily performed in basic ER clinics and primary care clinics."-- Provided by publisher.
Keywords	Dogs/Diseases/Treatment
Subject code	636.08959
Language	English
Size	1 online resource (212 pages)
Publisher	CAB International
Publishing place	Wallingford, Oxfordshire, UK
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	1-78924-300-9 ; 1-78924-299-1 ; 978-1-78924-300-0 ; 978-1-78924-299-7
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Gene-targeted therapies: Overview and implications.

Brooks, P J / Urv, Tiina K / Parisi, Melissa A

American journal of medical genetics. Part C, Seminars in medical genetics

2023 Volume 193, Issue 1, Page(s) 13–18

Abstract: Gene-targeted therapies (GTTs) are therapeutic platforms that are in principle applicable to large numbers of monogenic diseases. The rapid development and implementation of GTTs have profound implications for rare monogenic disease therapy development. ... ...

Abstract	Gene-targeted therapies (GTTs) are therapeutic platforms that are in principle applicable to large numbers of monogenic diseases. The rapid development and implementation of GTTs have profound implications for rare monogenic disease therapy development. This article provides a brief summary of the primary types of GTTs and a brief overview of the current state of the science. It also serves as a primer for the articles in this special issue.
MeSH term(s)	Humans ; Genetic Therapy
Language	English
Publishing date	2023-03-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2108622-9
ISSN	1552-4876 ; 0148-7299 ; 1552-4868
ISSN (online)	1552-4876
ISSN	0148-7299 ; 1552-4868
DOI	10.1002/ajmg.c.32033
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Article ; Online: Modelling social networks for children of parents with severe and enduring mental illness: an evidence based modification to the network episode model.

Nevard, Imogen / Brooks, Helen / Gellatly, Judith / Bee, Penny

BMC psychology

2024 Volume 12, Issue 1, Page(s) 162

Abstract: The Network Episode Model (NEM) is a well utilised model conceptualising how social networks, valuable resources which can positively impact wellbeing and functional outcomes, are responsive to the needs of people with physical and mental health ... ...

Abstract	The Network Episode Model (NEM) is a well utilised model conceptualising how social networks, valuable resources which can positively impact wellbeing and functional outcomes, are responsive to the needs of people with physical and mental health difficulties. Children of parents with severe and enduring mental illness (COPMI) are impacted by these illnesses through the intersecting roles of kin relation, informal carer, and dependent. However, it is not clear that social networks effectively respond in kind to the child's episodic need.We draw upon qualitative data to propose a new multi-factorial conceptual model (COPMI-NEM), triangulating parental mental illness, child's developmental stage and social ties to theorise how social networks do respond and adapt to children's needs.The model illustrates how networks are typically flexible and responsive to visible age-related needs, but less reactive to more obscured needs. Successful network navigation and negotiation of support relies on multiple factors including the child's ability to successfully activate social ties and the availability of formal networks. We propose a new theoretically and empirically informed NEM model also available for testing, refinement and validation in other young carer populations exposed to episodic parental health needs. Findings from this study could be used to generate network informed interventions for this and comparable populations.
MeSH term(s)	Child ; Humans ; Mental Disorders/psychology ; Parents/psychology ; Mental Health ; Social Networking ; Caregivers/psychology
Language	English
Publishing date	2024-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2705921-2
ISSN	2050-7283 ; 2050-7283
ISSN (online)	2050-7283
ISSN	2050-7283
DOI	10.1186/s40359-024-01647-3
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Article ; Online: Structure of the murine CD94-NKG2A receptor in complex with Qa-1

MacLachlan, Bruce J / Sullivan, Lucy C / Brooks, Andrew G / Rossjohn, Jamie / Vivian, Julian P

The FEBS journal

2024 Volume 291, Issue 7, Page(s) 1530–1544

Abstract: The heterodimeric natural killer cells antigen CD94 (CD94)-NKG2-A/NKG2-B type II integral membrane protein (NKG2A) receptor family expressed on human and mouse natural killer (NK) cells monitors global major histocompatibility complex (MHC) class I cell ... ...

Abstract	The heterodimeric natural killer cells antigen CD94 (CD94)-NKG2-A/NKG2-B type II integral membrane protein (NKG2A) receptor family expressed on human and mouse natural killer (NK) cells monitors global major histocompatibility complex (MHC) class I cell surface expression levels through binding to MHC class Ia-derived leader sequence peptides presented by HLA class I histocompatibility antigen, alpha chain E (HLA-E; in humans) or H-2 class I histocompatibility antigen, D-37 (Qa-1
MeSH term(s)	Animals ; Humans ; Mice ; Histocompatibility Antigens Class I/genetics ; Histocompatibility Antigens Class I/metabolism ; HLA Antigens/genetics ; HLA Antigens/metabolism ; HLA-E Antigens ; Killer Cells, Natural ; NK Cell Lectin-Like Receptor Subfamily C/genetics ; NK Cell Lectin-Like Receptor Subfamily C/metabolism ; NK Cell Lectin-Like Receptor Subfamily D/genetics ; NK Cell Lectin-Like Receptor Subfamily D/chemistry ; Peptides/metabolism ; Protein Sorting Signals ; Receptors, Natural Killer Cell/metabolism
Chemical Substances	Histocompatibility Antigens Class I ; HLA Antigens ; HLA-E Antigens ; NK Cell Lectin-Like Receptor Subfamily C ; NK Cell Lectin-Like Receptor Subfamily D ; Peptides ; Protein Sorting Signals ; Receptors, Natural Killer Cell
Language	English
Publishing date	2024-01-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2173655-8
ISSN	1742-4658 ; 1742-464X
ISSN (online)	1742-4658
ISSN	1742-464X
DOI	10.1111/febs.17050
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Article ; Online: Metabolomic profiling of wild rooibos (Aspalathus linearis) ecotypes and their antioxidant-derived phytopharmaceutical potential.

Wilkinson, C / Brooks, J / Stander, M A / Malgas, R / Roodt-Wilding, R / Makunga, N P

Metabolomics : Official journal of the Metabolomic Society

2024 Volume 20, Issue 3, Page(s) 45

Abstract: Introduction: Aspalathus linearis (commonly known as rooibos) is endemic to the Cape Floristic Region of South Africa and is a popular herbal drink and skin phytotherapeutic ingredient, with health benefits derived primarily from its unique phenolic ... ...

Abstract	Introduction: Aspalathus linearis (commonly known as rooibos) is endemic to the Cape Floristic Region of South Africa and is a popular herbal drink and skin phytotherapeutic ingredient, with health benefits derived primarily from its unique phenolic content. Several, seemingly habitat-specific ecotypes from the Cederberg (Western Cape) and Northern Cape have morphological, ecological, genetic and biochemical differences. Objectives and methods: Despite the commercial popularity of the cultivated variety, the uncultivated ecotypes are largely understudied. To address gaps in knowledge about the biochemical constituency, ultra-performance liquid chromatography-mass spectrometry analysis of fifteen populations was performed, enabling high-throughput metabolomic fingerprinting of 50% (v/v) methanolic extracts. Antioxidant screening of selected populations was performed via three assays and antimicrobial activity on two microbial species was assessed. The metabolomic results were corroborated with total phenolic and flavonoid screening of the extracts. Results and discussion: Site-specific chemical lineages of rooibos ecotypes were confirmed via multivariate data analyses. Important features identified via PLS-DA disclosed higher relative abundances of certain tentative metabolites (e.g., rutin, aspalathin and apiin) present in the Dobbelaarskop, Blomfontein, Welbedacht and Eselbank sites, in comparison to other locations. Several unknown novel metabolites (e.g., m/z 155.0369, 231.0513, 443.1197, 695.2883) are responsible for metabolomic separation of the populations, four of which showed higher amounts of key metabolites and were thus selected for bioactivity analysis. The Welbedacht and Eselbank site 2 populations consistently displayed higher antioxidant activities, with 2,2-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activities of 679.894 ± 3.427 µmol Trolox/g dry matter and 635.066 ± 5.140 µmol Trolox/g dry matter, respectively, in correlation with a high number of phenolic and flavonoid compounds. The contribution of the individual metabolites to the pharmacological effectiveness of rooibos remains unknown and as such, further structural elucidation and phytopharmacological testing is thus urgently needed.
MeSH term(s)	Aspalathus ; Antioxidants ; Ecotype ; Metabolomics ; Flavonoids ; Phenols
Chemical Substances	Antioxidants ; Flavonoids ; Phenols
Language	English
Publishing date	2024-04-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2250617-2
ISSN	1573-3890 ; 1573-3882
ISSN (online)	1573-3890
ISSN	1573-3882
DOI	10.1007/s11306-024-02103-4
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Zs.A 6361: Show issues

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Article ; Online: Serotonin and norepinephrine reuptake inhibitors association with dry mouth in a hospital population.

Katz, Joseph / Brooks, Shannen

Quintessence international (Berlin, Germany : 1985)

2023 Volume 54, Issue 2, Page(s) 150–154

Abstract: ... CI 5.47 to 6.48, P < .0001). The odds ratio for dry mouth in females on SNRI was 5.48 (95% CI 4.97 ... to 6.02, P < .0001), for males 5.48 (95% CI 4.56 to 6.95), P < .0001), for children 2.87 (95% CI 1.19 ... to 6.96, P = .0192), and for adults 4.46 (95% CI 4.09 to 4.86, P < .0001). When the different SNRIs ...

Abstract	Objectives: Xerostomia, or dry mouth, is a condition that results from the reduction or absence of saliva flow secondary to the use of certain medications. The objective of the present study was to analyze the relationship between xerostomia patients and the consumption of serotonin norepinephrine reuptake inhibitors (SNRIs). Method and materials: The University of Florida (UF) Integrated Data (IDR) i2b2, for the period of June 2015 to September 2022, was used based on aggregates of the International Classification of Diseases 10th edition (ICD-10) diagnoses of dry mouth and use of SNRI. MedCalc Software was used to calculate odds ratios. Results: The odds ratio for dry mouth in the SNRI group was 5.95 (95% CI 5.47 to 6.48, P < .0001). The odds ratio for dry mouth in females on SNRI was 5.48 (95% CI 4.97 to 6.02, P < .0001), for males 5.48 (95% CI 4.56 to 6.95), P < .0001), for children 2.87 (95% CI 1.19 to 6.96, P = .0192), and for adults 4.46 (95% CI 4.09 to 4.86, P < .0001). When the different SNRIs were analyzed separately, the odds ratio for dry mouth with the use of venlafaxine was 5.83 (95% CI 5.12 to 6.6, P < .0001), duloxetine 6.97 (95% CI 6.33 to 7.67, P <.0001), desvenlafaxine 5.24 (95% CI 3.65 to 7.52, P < .0001), and milnacipran 9.61 (95% CI 5.66 to 16.31, P < .0001). Conclusion: According to the present study, patients who are taking SNRIs are five-fold more likely to develop dry mouth compared to those not on medications. The results could be informative to medical professionals who prescribe SNRIs and who are not currently aware of the effect they have on salivary production and therefore quality of life, as well as the dental practitioners treating these patients with dry mouth sequalae. (Quintessence Int 2023;54:150-154; doi: 10.3290/j.qi.b3704403).
MeSH term(s)	Male ; Adult ; Female ; Child ; Humans ; Serotonin and Noradrenaline Reuptake Inhibitors/adverse effects ; Serotonin ; Quality of Life ; Dentists ; Professional Role ; Selective Serotonin Reuptake Inhibitors ; Norepinephrine ; Xerostomia/chemically induced
Chemical Substances	Serotonin and Noradrenaline Reuptake Inhibitors ; Serotonin (333DO1RDJY) ; Selective Serotonin Reuptake Inhibitors ; Norepinephrine (X4W3ENH1CV)
Language	English
Publishing date	2023-01-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	7436-6
ISSN	1936-7163 ; 0033-6572
ISSN (online)	1936-7163
ISSN	0033-6572
DOI	10.3290/j.qi.b3704403
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Article ; Online: Developmental framework for a desktop hydrogeomorphic wetland functional assessment derived from field-based data.

Backhaus, Peter J / Wardrop, Denice H / McCarty, Gregory W / Brooks, Robert P

Environmental monitoring and assessment

2024 Volume 196, Issue 2, Page(s) 217

Abstract: With loss of wetlands and their associated ecosystem services within landscapes, it is imperative to be able to understand the change in ecological functions underlying these services. Field-based functional assessments can produce a range of specific ... ...

Abstract	With loss of wetlands and their associated ecosystem services within landscapes, it is imperative to be able to understand the change in ecological functions underlying these services. Field-based functional assessments can produce a range of specific scores among a robust set of functions but are time and cost prohibitive as the number of wetlands assessed increases. Remote-based functional assessments are an alternative for broad scale assessments, but trade-off cost for limitations in scoring and functional assemblage. To address these concerns, we created a framework for the development of the Hydrogeomorphic Remote Assessment of Wetland Function (HGM-RAWF). Rooted in the hydrogeomorphic approach of an existing field-based functional assessment and its underlying models, this remote functional assessment substitutes field-based assessment methods with remotely assessed proxies. As potential remote proxies were determined through literature review and statistically screened for use in the remote assessment, a field-based reference wetland database of 222 freshwater wetlands in the Mid-Atlantic Region provided a baseline by which remote data could be compared and calibrated. The resulting HGM-RAWF protocol remotely assesses seven hydrology and biogeochemistry functions in the Mid-Atlantic with assessment scores similar to its field-based counterparts. With noted limitations, the HGM-RAWF framework provides the means to create desktop functional assessments across broad geographic scales with the diversity and specificity of field-based assessments at the reduced costs associated with remote assessments. Its basis in the HGM approach and use of public spatial datasets allows the framework to be adopted regionally and can be used as a model for national wetland functional assessment.
MeSH term(s)	Wetlands ; Ecosystem ; Environmental Monitoring/methods ; Hydrology ; Mid-Atlantic Region ; Conservation of Natural Resources
Language	English
Publishing date	2024-01-30
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-024-12373-z
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Article ; Online: Pretesting Discrete-Choice Experiments: A Guide for Researchers.

Campoamor, Nicola B / Guerrini, Christi J / Brooks, Whitney Bash / Bridges, John F P / Crossnohere, Norah L

The patient

2024 Volume 17, Issue 2, Page(s) 109–120

Abstract: Discrete-choice experiments (DCEs) are a frequently used method to explore the preferences of patients and other decision-makers in health. Pretesting is an essential stage in the design of a high-quality choice experiment and involves engaging with ... ...

Abstract	Discrete-choice experiments (DCEs) are a frequently used method to explore the preferences of patients and other decision-makers in health. Pretesting is an essential stage in the design of a high-quality choice experiment and involves engaging with representatives of the target population to improve the readability, presentation, and structure of the preference instrument. The goal of pretesting in DCEs is to improve the validity, reliability, and relevance of the survey, while decreasing sources of bias, burden, and error associated with preference elicitation, data collection, and interpretation of the data. Despite its value to inform DCE design, pretesting lacks documented good practices or clearly reported applied examples. The purpose of this paper is: (1) to define pretesting and describe the pretesting process specifically in the context of a DCE, (2) to present a practical guide and pretesting interview discussion template for researchers looking to conduct a rigorous pretest of a DCE, and (3) to provide an illustrative example of how these resources were operationalized to inform the design of a complex DCE aimed at eliciting tradeoffs between personal privacy and societal benefit in the context of a police method known as investigative genetic genealogy (IGG).
MeSH term(s)	Humans ; Choice Behavior ; Reproducibility of Results ; Patient Preference ; Surveys and Questionnaires
Language	English
Publishing date	2024-02-16
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2466680-4
ISSN	1178-1661 ; 1178-1653
ISSN (online)	1178-1661
ISSN	1178-1653
DOI	10.1007/s40271-024-00672-z
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Article ; Online: Healthcare professionals' experiences of caring for women with false-positive screening test results in the National Health Service Breast Screening Programme.

Long, Hannah A / Brooks, Joanna M / Maxwell, Anthony J / Peters, Sarah / Harvie, Michelle / French, David P

Health expectations : an international journal of public participation in health care and health policy

2024 Volume 27, Issue 2, Page(s) e14023

Abstract: Background: Understanding healthcare professionals' (HCPs) experiences of caring for women with false-positive screening test results in the National Health Service Breast Screening Programme (NHSBSP) is important for reducing the impact of such results. ...

Abstract	Background: Understanding healthcare professionals' (HCPs) experiences of caring for women with false-positive screening test results in the National Health Service Breast Screening Programme (NHSBSP) is important for reducing the impact of such results. Methods: Interviews were undertaken with 12 HCPs from a single NHSBSP unit, including advanced radiographer practitioners, breast radiographers, breast radiologists, clinical nurse specialists (CNSs), and a radiology healthcare assistant. Data were analysed thematically using Template Analysis. Results: Two themes were produced: (1) Gauging and navigating women's anxiety during screening assessment was an inevitable and necessary task for all participants. CNSs were perceived as particularly adept at this, while breast radiographers reported a lack of adequate formal training. (2) Controlling the delivery of information to women (including amount, type and timing of information). HCPs reported various communication strategies to facilitate women's information processing and retention during a distressing time. Conclusions: Women's anxiety could be reduced through dedicated CNS support, but this should not replace support from other HCPs. Breast radiographers may benefit from more training to emotionally support recalled women. While HCPs emphasised taking a patient-centred communication approach, the use of other strategies (e.g., standardised scripts) and the constraints of the 'one-stop shop' model pose challenges to such an approach. Patient and public contribution: During the study design, two Patient and Public Involvement members (women with false-positive-breast screening test results) were consulted to gain an understanding of patient perspectives and experiences of being recalled specifically in the NHSBSP. Their feedback informed the formulations of the research aim, objectives and the direction of the interview guide.
MeSH term(s)	Female ; Humans ; State Medicine ; Mammography/psychology ; Health Personnel ; Allied Health Personnel ; Delivery of Health Care ; Breast Neoplasms/diagnosis ; Qualitative Research
Language	English
Publishing date	2024-03-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2119434-8
ISSN	1369-7625 ; 1369-6513
ISSN (online)	1369-7625
ISSN	1369-6513
DOI	10.1111/hex.14023
Database	MEDical Literature Analysis and Retrieval System OnLINE

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