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Article: Do journals and corporate sponsors back certain views in topics where disagreement prevails?

Ingwersen, Peter / Holm, Soeren / Larsen, Birger / Ploug, Thomas

2020 Volume 126, Issue 1, Page(s) 389–415

Abstract: The article focuses on scientific disagreement about the use of statin-related drugs in the prevention of cardiovascular events. The study forms part of an exploration of the broader principle of research polarization, foremost in medicine. The ... ...

Abstract	The article focuses on scientific disagreement about the use of statin-related drugs in the prevention of cardiovascular events. The study forms part of an exploration of the broader principle of research polarization, foremost in medicine. The hypothesis is that statin-positive and statin-critical researchers publish in different committed central journals, and that they are financially supported by different dedicated corporate sources. Methodologically we use Web of Science (WoS) analytic tools to perform publication analysis of a time series covering 1998-2018 in three seven-year windows. For each window data is captured based on sets of known statin-positive and statin-critical articles and researchers, and their primary and secondary co-authors. Standard deviation is used as a focused normalization and visual instrument together with Spearman's correlation coefficient in order to compare frequency distributions of statin-positive and critical journal and sponsor articles.
Keywords	covid19
Language	English
Publishing date	2020-10-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	435652-4
ISSN	0138-9130
ISSN	0138-9130
DOI	10.1007/s11192-020-03743-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Schonender und hilfreicher Umgang mit Trauma in der Aufstellungsarbeit

Ingwersen, Dagmar

(In: Nazarkiewicz, Kirsten; Bourquin, Peter (Ed.), Trauma und Begegnung. Praxis der Systemaufstellung (S. 97-112). Göttingen: Vandenhoeck & Ruprecht (Serie: Jahrbuch der Deutschen Gesellschaft für Systemaufstellungen))

2017

Abstract: Es werden Beobachtungen, Anregungen und Hypothesen zur Frage erörtert, wie Retraumatisierungen, die durch die Aufstellungsarbeit ausgelöst werden könnten, verhindert werden können. Zunächst werden anhand eines Werkstattberichts einige Beobachtungen ... ...

Title translation	Gentle and helpful handling of trauma in constellation work
Series title	In: Nazarkiewicz, Kirsten; Bourquin, Peter (Ed.), Trauma und Begegnung. Praxis der Systemaufstellung (S. 97-112). Göttingen: Vandenhoeck & Ruprecht (Serie: Jahrbuch der Deutschen Gesellschaft für Systemaufstellungen)
Abstract	Es werden Beobachtungen, Anregungen und Hypothesen zur Frage erörtert, wie Retraumatisierungen, die durch die Aufstellungsarbeit ausgelöst werden könnten, verhindert werden können. Zunächst werden anhand eines Werkstattberichts einige Beobachtungen wiedergeben, die mit traumatisierten Patienten in einem klinischen Setting gemacht wurden; dabei fließen auch Erfahrungen mit Aufstellungskursen für nicht stationäre Teilnehmer ein. Folgende Aspekte werden thematisiert: Dissoziation und die Folgen für die Aufstellungsarbeit; Traumaenergie und Veränderung; der Stellenwert traumaspezifischer Einzelarbeit; Traumaeinzelarbeit auf der transgenerationalen Ebene; der Stellenwert der Aufstellungsarbeit für die Lösung von Trauma; die "vorbereitende" Aufstellung mit abstrakten Elementen; Auflösung von Trauma innerhalb der Aufstellung; mögliche Retraumatisierung durch Stellvertreterrollen (mit einer Kasuistik).
Keywords	Dissociation ; Dissoziation ; Emotional Trauma ; Emotionales Trauma ; Familiensystemtheorie ; Family Systems Theory ; Psychotherapeutic Processes ; Psychotherapeutic Techniques ; Psychotherapeutische Prozesse ; Psychotherapeutische Techniken ; Psychotherapie ; Psychotherapy ; Transgenerational Patterns ; Transgenerationale Verhaltensmuster
Language	German
Document type	Article
Database	PSYNDEX

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Article ; Online: Selección de ejemplos fundamentales de análisis de publicaciones cienciométricas - See more at

Ingwersen, Peter

BiD: Textos Universitaris de Biblioteconomia i Documentació, Iss

http://bid.ub.edu/es/32/ingwersen2.htm#sthash.sMqADZ8E.dpuf

2014 Volume 32

Abstract: Objetivos: detallar una selección de factores de importancia capital para calcular, presentar e interpretar los resultados de análisis de publicaciones desde una óptica cienciométrica, en particular con relación al análisis del crecimiento y de las ... ...

Abstract	Objetivos: detallar una selección de factores de importancia capital para calcular, presentar e interpretar los resultados de análisis de publicaciones desde una óptica cienciométrica, en particular con relación al análisis del crecimiento y de las cuotas mundiales, así como la lógica que hay detrás del cálculo de las medias de autores, instituciones o países por publicación indexados por Web of Science. -- Metodología: ejemplos de estudios sobre evaluación de investigación anteriores y también de casos basados en datos recogidos en línea para este artículo demuestran conflictos, detalles problemáticos, inconvenientes y cómo superarlos en el análisis de publicaciones con respecto a la aplicación, al cálculo, a la presentación y a la interpretación de herramientas analíticas. -- Resultados: proporciona una visión de la cienciometría en el contexto del análisis infométrico, casos seleccionados de productividad de investigación, patrones y tendencias de investigación de publicaciones en todas las disciplinas y en los campos de la energía renovable y la energía eólica en diferentes periodos de tiempo y mediante diferentes tipos de análisis y presentación.Objective: This paper selects and outlines factors of central importance in the calculation, presentation and interpretation of publication analysis results from a scientometric perspective. The paper focuses on growth, world share analyses and the logic behind the computation of average numbers of authors, institutions or countries per publication indexed by Web of Science. -- Methodology: The paper uses examples from earlier research evaluation studies and cases based on online data to describe issues, problematic details, pitfalls and how to overcome them in publication analysis with respect to analytic tool application, calculation, presentation and interpretation. -- Results: By means of different kinds of analysis and presentation, the paper provides insight into scientometrics in the context of informetric analysis, selected cases of research productivity, ...
Keywords	Scientometrics ; Bibliography. Library science. Information resources ; Z
Language	Catalan
Publishing date	2014-06-01T00:00:00Z
Publisher	Universitat de Barcelona & Universitat Oberta de Catalunya
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Selected critical examples of scientometric publication analysis

Ingwersen, Peter

BiD: Textos Universitaris de Biblioteconomia i Documentació, Iss

2014 Volume 32

Abstract	Objetivos: detallar una selección de factores de importancia capital para calcular, presentar e interpretar los resultados de análisis de publicaciones desde una óptica cienciométrica, en particular con relación al análisis del crecimiento y de las cuotas mundiales, así como la lógica que hay detrás del cálculo de las medias de autores, instituciones o países por publicación indexados por Web of Science. -- Metodología: ejemplos de estudios sobre evaluación de investigación anteriores y también de casos basados en datos recogidos en línea para este artículo demuestran conflictos, detalles problemáticos, inconvenientes y cómo superarlos en el análisis de publicaciones con respecto a la aplicación, al cálculo, a la presentación y a la interpretación de herramientas analíticas. -- Resultados: proporciona una visión de la cienciometría en el contexto del análisis infométrico, casos seleccionados de productividad de investigación, patrones y tendencias de investigación de publicaciones en todas las disciplinas y en los campos de la energía renovable y la energía eólica en diferentes periodos de tiempo y mediante diferentes tipos de análisis y presentación.Objective: This paper selects and outlines factors of central importance in the calculation, presentation and interpretation of publication analysis results from a scientometric perspective. The paper focuses on growth, world share analyses and the logic behind the computation of average numbers of authors, institutions or countries per publication indexed by Web of Science. -- Methodology: The paper uses examples from earlier research evaluation studies and cases based on online data to describe issues, problematic details, pitfalls and how to overcome them in publication analysis with respect to analytic tool application, calculation, presentation and interpretation. -- Results: By means of different kinds of analysis and presentation, the paper provides insight into scientometrics in the context of informetric analysis, selected cases of research productivity, ...
Keywords	Scientometrics ; Bibliography. Library science. Information resources ; Z
Language	Catalan
Publishing date	2014-06-01T00:00:00Z
Publisher	Universitat de Barcelona & Universitat Oberta de Catalunya
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Selecció d'exemples fonamentals d'anàlisis de publicacions cienciomètriques

Ingwersen, Peter

BiD: Textos Universitaris de Biblioteconomia i Documentació, Iss

2014 Volume 32

Abstract: Objectius: detallar una selecció de factors d'importància cabdal per calcular, presentar i interpretar els resultats d'anàlisis de publicacions des d'una perspectiva cienciomètrica, en particular amb relació a l'anàlisi del creixement i de les quotes ... ...

Abstract	Objectius: detallar una selecció de factors d'importància cabdal per calcular, presentar i interpretar els resultats d'anàlisis de publicacions des d'una perspectiva cienciomètrica, en particular amb relació a l'anàlisi del creixement i de les quotes mundials, i també la lògica que hi ha darrere del càlcul de les mitjanes d'autors, institucions o països per publicació indexats pel Web of Science. -- Metodologia: exemples d'estudis sobre avaluació de recerca anteriors i també de casos que es basen en dades recollides en línia per a aquest article demostren conflictes, detalls problemàtics, inconvenients i com superar-los en l'anàlisi de publicacions respecte de l'aplicació, del càlcul, de la presentació i de la interpretació d'eines analítiques. -- Resultats: proporciona una visió de la cienciometria en el context de l'anàlisi infomètrica, casos seleccionats de productivitat de recerca, patrons i tendències de recerca de publicacions en totes les disciplines i en els camps de l'energia renovable i l'energia eòlica en diferents períodes de temps i a través de diferents tipus d'anàlisi i presentació.Objective: This paper selects and outlines factors of central importance in the calculation, presentation and interpretation of publication analysis results from a scientometric perspective. The paper focuses on growth, world share analyses and the logic behind the computation of average numbers of authors, institutions or countries per publication indexed by Web of Science. -- Methodology: The paper uses examples from earlier research evaluation studies and cases based on online data to describe issues, problematic details, pitfalls and how to overcome them in publication analysis with respect to analytic tool application, calculation, presentation and interpretation. -- Results: By means of different kinds of analysis and presentation, the paper provides insight into scientometrics in the context of informetric analysis, selected cases of research productivity, publication patterns and research trends in the fields of ...
Keywords	Scientometrics ; Bibliography. Library science. Information resources ; Z
Language	Catalan
Publishing date	2014-06-01T00:00:00Z
Publisher	Universitat de Barcelona & Universitat Oberta de Catalunya
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of Previous Disease-Modifying Therapy on Treatment Effectiveness for Patients Treated With Ocrelizumab.

Pfeuffer, Steffen / Rolfes, Leoni / Ingwersen, Jens / Pul, Refik / Kleinschnitz, Konstanze / Korsen, Melanie / Räuber, Saskia / Ruck, Tobias / Schieferdecker, Simon / Willison, Alice Grizzel / Aktas, Orhan / Kleinschnitz, Christoph / Hartung, Hans-Peter / Kappos, Ludwig / Meuth, Sven G

Neurology(R) neuroimmunology & neuroinflammation

2023 Volume 10, Issue 3

Abstract: Background and objectives: B cell-depleting antibodies were proven as effective strategy for the treatment of relapsing multiple sclerosis (RMS). The monoclonal antibody ocrelizumab was approved in 2017 in the United States and in 2018 in the European ... ...

Abstract	Background and objectives: B cell-depleting antibodies were proven as effective strategy for the treatment of relapsing multiple sclerosis (RMS). The monoclonal antibody ocrelizumab was approved in 2017 in the United States and in 2018 in the European Union, but despite proven efficacy in randomized, controlled clinical trials, its effectiveness in the real-world setting remains to be fully elucidated. In particular, most study patients were treatment naive or switched from injectable therapies, whereas oral substances or monoclonal antibodies made up >1% of previous treatments. Methods: We evaluated ocrelizumab-treated patients with RMS enrolled in the prospective cohorts at the University Hospitals Duesseldorf and Essen, Germany. Epidemiologic data at baseline were compared, and Cox proportional hazard models were applied to evaluate outcomes. Results: Two hundred eighty patients were included (median age: 37 years, 35% male patients). Compared with using ocrelizumab as a first-line treatment, its use as a third-line therapy increased hazard ratios (HRs) for relapse and disability progression, whereas differences between first- vs second-line and second- vs third-line remained smaller. We stratified patients according to their last previous disease-modifying treatment and here identified fingolimod (FTY) (45 patients, median age 40 years, 33% male patients) as a relevant risk factor for ongoing relapse activity despite 2nd-line (HR: 3.417 [1.007-11.600]) or 3rd-line (HR: 5.903 [2.489-13.999]) ocrelizumab treatment, disability worsening (2nd line: HR: 3.571 [1.013-12.589]; 3rd line: HR: 4.502 [1.728-11.729]), and occurrence of new/enlarging MRI lesions (2nd line: HR: 1.939 [0.604-6.228]; 3rd line: HR: 4.627 [1.982-10.802]). Effects were persistent throughout the whole follow-up. Neither peripheral B-cell repopulation nor immunoglobulin G levels were associated with rekindling disease activity. Discussion: Our prospectively collected observational data suggest suboptimal effectiveness of ocrelizumab in patients switching from FTY compared with those switching from other substances or having been treatment naive. These findings support previous studies indicating abated effectiveness of immune cell-depleting therapies following FTY treatment in patients with RMS. Classification of evidence: This study provides Class IV evidence that for patients with RMS, previous treatment with FTY compared with previous treatment with other immunomodulating therapies decreases the effectiveness of ocrelizumab.
MeSH term(s)	Humans ; Male ; United States ; Adult ; Female ; Multiple Sclerosis, Relapsing-Remitting/drug therapy ; Prospective Studies ; Multiple Sclerosis/drug therapy ; Treatment Outcome ; Antilymphocyte Serum ; Recurrence
Chemical Substances	ocrelizumab (A10SJL62JY) ; Antilymphocyte Serum
Language	English
Publishing date	2023-04-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2767740-0
ISSN	2332-7812 ; 2332-7812
ISSN (online)	2332-7812
ISSN	2332-7812
DOI	10.1212/NXI.0000000000200104
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Thesis: Über die Reaktion des Virus N mit einem Seruminhibitor

Ingwersen, Peter

1970

Author's details	Peter Ingwersen
Language	German
Size	55 S.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Gießen, Univ., Diss., 1970
HBZ-ID	HT014599447
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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DissJ 7332	order for loan	Geschlossenes Magazin (U2)

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Article ; Conference proceedings: Regional grey-matter A1 adenosine receptor expression in patients with early-stage Multiple Sclerosis: An in vivo PET study

Schweda, V. / Graf, J. / Elmenhorst, D. / Matusch, A. / Ingwersen, J. / Neumaier, B. / Aktas, O. / Bauer, A. / Kroll, T.

Nuklearmedizin - NuclearMedicine

2023 Volume 62, Issue 02

Event/congress	61. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, Leipzig, 2023-04-19
Language	German
Publishing date	2023-03-30
Publisher	Georg Thieme Verlag
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	2030804-8
ISSN	2567-6407 ; 0029-5566
ISSN (online)	2567-6407
ISSN	0029-5566
DOI	10.1055/s-0043-1766271
Database	Thieme publisher's database

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Article ; Online: Advances in and Algorithms for the Treatment of Relapsing-Remitting Multiple Sclerosis.

Ingwersen, Jens / Aktas, Orhan / Hartung, Hans-Peter

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

2015 Volume 13, Issue 1, Page(s) 47–57

Abstract: Treatment options in relapsing-remitting multiple sclerosis have increased considerably in recent years; currently, a dozen different preparations of disease-modifying therapies are available and some more are expected to be marketed soon. For the ... ...

Abstract	Treatment options in relapsing-remitting multiple sclerosis have increased considerably in recent years; currently, a dozen different preparations of disease-modifying therapies are available and some more are expected to be marketed soon. For the treating neurologist this broad therapeutic repertoire not only greatly improves individualized management of the disease, but also makes choices more complex and difficult. A number of factors must be considered, including disease activity and severity, safety profile, and patient preference. We here discuss the currently existing options and suggest treatment algorithms for managing relapsing-remitting multiple sclerosis.
MeSH term(s)	Alemtuzumab ; Algorithms ; Antibodies, Monoclonal, Humanized/therapeutic use ; Crotonates/therapeutic use ; Dimethyl Fumarate/therapeutic use ; Fingolimod Hydrochloride/therapeutic use ; Glatiramer Acetate/therapeutic use ; Humans ; Hydroxybutyrates ; Interferon-beta/therapeutic use ; Multiple Sclerosis, Relapsing-Remitting/drug therapy ; Natalizumab/therapeutic use ; Nitriles ; Toluidines/therapeutic use
Chemical Substances	Antibodies, Monoclonal, Humanized ; Crotonates ; Hydroxybutyrates ; Natalizumab ; Nitriles ; Toluidines ; teriflunomide (1C058IKG3B) ; Alemtuzumab (3A189DH42V) ; Glatiramer Acetate (5M691HL4BO) ; Interferon-beta (77238-31-4) ; Dimethyl Fumarate (FO2303MNI2) ; Fingolimod Hydrochloride (G926EC510T)
Language	English
Publishing date	2015-12-23
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2316693-9
ISSN	1878-7479 ; 1933-7213
ISSN (online)	1878-7479
ISSN	1933-7213
DOI	10.1007/s13311-015-0412-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: CNS Involvement in Chronic Inflammatory Demyelinating Polyneuropathy: Subtle Retinal Changes in Optical Coherence Tomography.

Ingwersen, Jens / Graf, Jonas / Kluge, Julia / Weise, Margit / Dietrich, Michael / Lee, John-Ih / Harmel, Jens / Hartung, Hans-Peter / Ruck, Tobias / Meuth, Sven G / Albrecht, Philipp / Aktas, Orhan / Ringelstein, Marius

Neurology(R) neuroimmunology & neuroinflammation

2021 Volume 9, Issue 1

Abstract: Background and objectives: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease primarily affecting the peripheral nervous system. However, several noncontrolled studies have suggested concomitant inflammatory CNS ... ...

Abstract	Background and objectives: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease primarily affecting the peripheral nervous system. However, several noncontrolled studies have suggested concomitant inflammatory CNS demyelination similar to multiple sclerosis. The aim of this study was to investigate an involvement of the visual pathway in patients with CIDP. Methods: In this prospective cross-sectional study, we used high-resolution spectral-domain optical coherence tomography to compare the thickness of the peripapillary retinal nerve fiber layer and the deeper macular retinal layers as well as the total macular volume (TMV) in 22 patients with CIDP and 22 age-matched and sex-matched healthy control (HC) individuals. Retinal layers were semiautomatically segmented by the provided software and were correlated with clinical measures and nerve conduction studies. Results: In patients with CIDP compared with healthy age-matched and sex-matched controls, we found slight but significant volume reductions of the ganglion cell/inner plexiform layer complex (CIDP 1.86 vs HC 1.95 mm Discussion: Our data reveal subtle retinal neurodegeneration in patients with CIDP, providing evidence for visual pathway involvement, detectable by OCT. The results need corroboration in independent, larger cohorts.
MeSH term(s)	Adult ; Aged ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Neural Conduction/physiology ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/diagnostic imaging ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/pathology ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/physiopathology ; Prospective Studies ; Retina/diagnostic imaging ; Retina/pathology ; Tomography, Optical Coherence ; Visual Pathways/diagnostic imaging ; Visual Pathways/pathology
Language	English
Publishing date	2021-10-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2767740-0
ISSN	2332-7812 ; 2332-7812
ISSN (online)	2332-7812
ISSN	2332-7812
DOI	10.1212/NXI.0000000000001099
Database	MEDical Literature Analysis and Retrieval System OnLINE

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