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  1. Article ; Online: Response to Gal Almogy: Superspreaders do matter.

    Beldomenico, Pablo M

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 98, Page(s) 187

    MeSH term(s) COVID-19 ; Disease Outbreaks ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-02
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.06.100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4516: Show issues Location:
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  2. Article ; Online: Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19.

    Beldomenico, Pablo M

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 96, Page(s) 461–463

    Abstract: The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this ...

    Abstract The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/transmission ; Humans ; Pandemics ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Serologic Tests ; Viral Load
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.05.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4516: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19

    Beldomenico, Pablo M.

    International Journal of Infectious Diseases

    2020  Volume 96, Page(s) 461–463

    Keywords Microbiology (medical) ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.05.025
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19

    Beldomenico, Pablo M

    Int J Infect Dis

    Abstract: The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this ...

    Abstract The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #232670
    Database COVID19

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  6. Article ; Online: Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19

    Pablo M. Beldomenico

    International Journal of Infectious Diseases, Vol 96, Iss , Pp 461-

    2020  Volume 463

    Abstract: The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this ...

    Abstract The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research.
    Keywords Superspreading ; COVID-19 ; Superspreader ; Transmission ; Propagation ; Epidemiology ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Positive feedback loops exacerbate the influence of superspreaders in disease transmission.

    Wanelik, Klara M / Begon, Mike / Fenton, Andy / Norman, Rachel A / Beldomenico, Pablo M

    iScience

    2023  Volume 26, Issue 5, Page(s) 106618

    Abstract: Superspreaders are recognized as being important drivers of disease spread. However, models to date have assumed random occurrence of superspreaders, irrespective of whom they were infected by. Evidence suggests though that those individuals infected by ... ...

    Abstract Superspreaders are recognized as being important drivers of disease spread. However, models to date have assumed random occurrence of superspreaders, irrespective of whom they were infected by. Evidence suggests though that those individuals infected by superspreaders may be more likely to become superspreaders themselves. Here, we begin to explore, theoretically, the effects of such a positive feedback loop on (1) the final epidemic size, (2) the herd immunity threshold, (3) the basic reproduction number,
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2023.106618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An integrative approach to explore species limits in Laelaps mazzai Fonseca, 1939 (Mesostigmata, Laelapidae), a South American widespread mite parasitizing the cricetid Calomys Waterhouse, 1837.

    Espinoza-Carniglia, Mario / Galliari, Carlos / Fantozzi, M Cecilia / Beldomenico, Pablo M / Lareschi, Marcela

    Acta tropica

    2023  Volume 240, Page(s) 106836

    Abstract: Laelaps mazzai Fonseca, 1939 (Mesostigmata, Laelapidae) parasitizes several species of the widespread South American rodent genus Calomys Waterhouse, 1837. Morphological variation has been noticed within this laelapid but has yet to be analyzed. Since ... ...

    Abstract Laelaps mazzai Fonseca, 1939 (Mesostigmata, Laelapidae) parasitizes several species of the widespread South American rodent genus Calomys Waterhouse, 1837. Morphological variation has been noticed within this laelapid but has yet to be analyzed. Since several other species of laelapids that initially were considered generalists have resulted in host-specific species, after further analyses, herein we explored, through morphology and genetics, the variation of this parasite across six species of Calomys, trying to establish if it constitutes a polymorphic species or a complex of cryptic host specific-species. An integrative approach was applied, including principal component and discriminant analyses of females and males and DNA sequences (nuclear region ITS and the COI gene). The obtained results indicate that female mites tend to differentiate only the sizes of their dorsal shield among host species but with extensive overlapping. At the same time the males lack metrical differentiation, and the genetic evidence failed to resolve specific-species clades. We conclude that L. mazzai is a single widespread mite with little genetic and phenotypic differentiation.
    MeSH term(s) Animals ; Male ; Female ; Mites ; Sigmodontinae/parasitology ; Arvicolinae/genetics ; Base Sequence ; Rodentia ; South America
    Language English
    Publishing date 2023-02-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 210415-5
    ISSN 1873-6254 ; 0001-706X
    ISSN (online) 1873-6254
    ISSN 0001-706X
    DOI 10.1016/j.actatropica.2023.106836
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    Ud II Zs.136: Show issues Location:
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  9. Article ; Online: Cattle Farming and Plantation Forest are Associated with Bartonella Occurrence in Wild Rodents.

    Colombo, Valeria C / Antoniazzi, Leandro R / Cicuttin, Gabriel L / De Salvo, María N / Beldomenico, Pablo M / Monje, Lucas D

    EcoHealth

    2024  Volume 20, Issue 4, Page(s) 381–389

    Abstract: Bartonella spp. are intracellular hemotropic bacteria primarily transmitted by arthropod vectors to various mammalian hosts, including humans. In this study, we conducted a survey on wild populations of sigmodontine rodents, Akodon azarae and Oxymycterus ...

    Abstract Bartonella spp. are intracellular hemotropic bacteria primarily transmitted by arthropod vectors to various mammalian hosts, including humans. In this study, we conducted a survey on wild populations of sigmodontine rodents, Akodon azarae and Oxymycterus rufus, inhabiting the Paraná River delta region. The study involved eight grids organized in a crossed 2 × 2 design, where four of the grids were exposed to cattle while the other four were not, and four grids were located in implanted forest while the remaining four were in natural grasslands. Our objective was to examine whether the occurrence of Bartonella spp. in rodents was associated with silvopastoral activities (cattle raising associated with timber production) conducted in the region. Additionally, we evaluated the associations between Bartonella infection and other environmental and host factors. We present compelling evidence of a significant positive association between Bartonella prevalence and the presence of implanted forests and cattle. Furthermore, we identified the presence of a Bartonella genotype related to the pathogen Bartonella rochalimaea, infecting both A. azarae and Ox. rufus. These findings suggest that anthropogenic land-use changes, particularly the development of silvopastoral practices in the region, may disrupt the dynamics of Bartonella.
    MeSH term(s) Animals ; Cattle ; Humans ; Bartonella ; Rodentia/microbiology ; Bartonella Infections/epidemiology ; Bartonella Infections/veterinary ; Sigmodontinae ; Forests ; Agriculture
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2164327-1
    ISSN 1612-9210 ; 1612-9202
    ISSN (online) 1612-9210
    ISSN 1612-9202
    DOI 10.1007/s10393-023-01671-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Z 7528: Show issues
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  10. Article ; Online: Natural infection of free-ranging capybaras (Hydrochoerus hydrochaeris) with Anaplasmataecea and Rickettsiaceae bacteria in the Iberá wetlands ecoregion, Argentina.

    Monje, Lucas D / Eberhardt, Ayelen T / Vaschalde, Paula J / Barolin, Johann / Costa, Francisco B / Labruna, Marcelo B / Beldomenico, Pablo M

    Veterinary research communications

    2024  Volume 48, Issue 2, Page(s) 1161–1169

    Abstract: The current work assessed the infection with Ehrlichia and Anaplasma species, and exposure to Rickettsia spp. in free-ranging capybaras in the Iberá wetlands ecoregion in Argentina. By indirect immunofluorescence assay, 37 out of 51 (73%) capybara sera ... ...

    Abstract The current work assessed the infection with Ehrlichia and Anaplasma species, and exposure to Rickettsia spp. in free-ranging capybaras in the Iberá wetlands ecoregion in Argentina. By indirect immunofluorescence assay, 37 out of 51 (73%) capybara sera were seropositive to Rickettsia spp., with 23.5% and 4% samples considered homologous to Rickettsia parkeri and Rickettsia bellii, respectively (or very closely related serotypes). Anaplasmataceae DNA was found to be highly prevalent in capybaras, with 33 out of 62 samples positive for Anaplasma sp. with Ct values of 28.64 ± 0.35 (average ± standard error), and 12 samples positive for Ehrlichia sp. with Ct values of 31.74 ± 0.87. Anaplasma sp. from capybaras was closely related to Anaplasma sp. reported to infect Amblyomma dubitatum in Iberá wetlands and to Anaplasma odocoilei, while the detected Ehrlichia sp. was closely related to "Candidatus Ehrlichia hydrochoerus" previously reported to infect capybaras in Brazil and A. dubitatum in Iberá wetlands. Structures compatible with Anaplasma morulae were observed in the cytoplasm of platelets from Anaplasma-positive capybaras. Our findings show that capybaras from the Iberá wetlands were exposed to Rickettsia species related to R. bellii and to the pathogen R. parkeri, and were infected with "Ca. Ehrlichia hydrochoerus" and a novel Anaplasma species, herein named "Candidatus Anaplasma capybara".
    MeSH term(s) Animals ; Rodentia ; Rickettsiaceae ; Wetlands ; Argentina ; Brazil
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-024-10301-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3453: Show issues Location:
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