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  1. Article ; Online: Rare desmoplastic trichilemmoma associated with sebaceous nevus.

    Jardim, Márcio Martins Lobo / Souza, Bruno de Castro E / Fraga, Renata Cavanellas / Fraga, Rafael Cavanellas

    Anais brasileiros de dermatologia

    2018  Volume 92, Issue 6, Page(s) 836–837

    Abstract: Nevus sebaceous of Jadassohn is a congenital hamartoma that usually affects the scalp and face. Several benign or malignant neoplasias may develop in the lesion and the most common are trichoblastoma, syringocystadenoma papilliferum, and basal cell ... ...

    Abstract Nevus sebaceous of Jadassohn is a congenital hamartoma that usually affects the scalp and face. Several benign or malignant neoplasias may develop in the lesion and the most common are trichoblastoma, syringocystadenoma papilliferum, and basal cell carcinoma. Trichilemmoma is a benign solid tumor originating from external sheath cells of pilosebaceous follicles. When it is characterized by a central zone of desmoplasia, it is called desmoplastic trichilemmoma. We report a case of a 58-year-old patient who developed a tumor in a sebaceous nevus. We performed a total excision of the lesion. Histopathological diagnosis was compatible with desmoplastic trichilemmoma. Our literature review reveals that the occurrence of trichilemmoma desmoplastic is unusual. Moreover, it can mimic an invasive carcinoma on histological and clinical examinations. This fact confirms the importance of reporting the occurrence of this rare cancer in a nevus sebaceous of Jadassohn.
    MeSH term(s) Carcinoma, Basal Cell/pathology ; Female ; Hair Diseases/etiology ; Hair Diseases/pathology ; Hair Follicle/pathology ; Humans ; Middle Aged ; Nevus, Sebaceous of Jadassohn/complications ; Nevus, Sebaceous of Jadassohn/pathology ; Rare Diseases ; Scalp/pathology ; Skin Neoplasms/pathology
    Language English
    Publishing date 2018-12-04
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/abd1806-4841.20176540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Do you know this syndrome? Heerfordt-Waldenström syndrome.

    Fraga, Rafael Cavanellas / Kakizaki, Priscila / Valente, Neusa Yuriko Sakai / Portocarrero, Larissa Karine Leite / Teixeira, Mônica Fernandes Senise / Senise, Priscilla Fernandes

    Anais brasileiros de dermatologia

    2017  Volume 92, Issue 4, Page(s) 571–572

    Abstract: Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the ... ...

    Abstract Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases.
    MeSH term(s) Adult ; Facial Paralysis/complications ; Female ; Granuloma/pathology ; Humans ; Parotid Diseases/complications ; Parotid Diseases/diagnosis ; Syndrome ; Uveoparotid Fever/complications ; Uveoparotid Fever/diagnosis
    Language English
    Publishing date 2017-09-25
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/abd1806-4841.20175211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Squamoid eccrine ductal carcinoma.

    Saraiva, Maria Isabel Ramos / Vieira, Marcella Amaral Horta Barbosa / Portocarrero, Larissa Karine Leite / Fraga, Rafael Cavanellas / Kakizaki, Priscila / Valente, Neusa Yuriko Sakai

    Anais brasileiros de dermatologia

    2017  Volume 91, Issue 6, Page(s) 799–802

    Abstract: Squamoid eccrine ductal carcinoma is an eccrine carcinoma subtype, and only twelve cases have been reported until now. It is a rare tumor and its histopathological diagnosis is difficult. Almost half of patients are misdiagnosed as squamous cell ... ...

    Abstract Squamoid eccrine ductal carcinoma is an eccrine carcinoma subtype, and only twelve cases have been reported until now. It is a rare tumor and its histopathological diagnosis is difficult. Almost half of patients are misdiagnosed as squamous cell carcinoma by the incisional biopsy. We report the thirteenth case of squamoid eccrine ductal carcinoma. Female patient, 72 years old, in the last 6 months presenting erythematous, keratotic and ulcerated papules on the nose. The incisional biopsy diagnosed squamoid eccrine ductal carcinoma. After excision, histopathology revealed positive margins. A wideningmargins surgery and grafting were performed, which again resulted in positive margins. The patient was then referred for radiotherapy. After 25 sessions, the injury reappeared. After another surgery, although the intraoperative biopsy showed free surgical margins, the product of resection revealed persistent lesion. Distinction between squamoid eccrine ductal carcinoma and squamous cell carcinoma is important because of the more aggressive nature of the first, which requires wider margins surgery to avoid recurrence.
    MeSH term(s) Aged ; Biopsy ; Carcinoma, Ductal/pathology ; Carcinoma, Ductal/therapy ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/therapy ; Eccrine Glands/pathology ; Female ; Humans ; Neoplasm Recurrence, Local ; Nose/pathology ; Sweat Gland Neoplasms/pathology ; Sweat Gland Neoplasms/therapy
    Language English
    Publishing date 2017-01-09
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/abd1806-4841.20164682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with etanercept.

    Vieira, Marcella Amaral Horta Barbosa / Saraiva, Maria Isabel Ramos / Silva, Larissa Karine Leite da / Fraga, Rafael Cavanellas / Kakizaki, Priscila / Valente, Neusa Yuriko Sakai

    Revista da Associacao Medica Brasileira (1992)

    2016  Volume 62, Issue 8, Page(s) 718–720

    Abstract: We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for ... ...

    Abstract We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for fungi and acid-fast bacilli (AFB). After discontinuation of etanercept, the patient's condition improved. Although apparently paradoxical, cases of cutaneous and systemic sarcoidosis after anti-TNF medications have been reported in the literature, with very few cases presenting exclusive cutaneous involvement.
    MeSH term(s) Antirheumatic Agents/adverse effects ; Arthritis, Rheumatoid/drug therapy ; Etanercept/adverse effects ; Female ; Humans ; Middle Aged ; Sarcoidosis/chemically induced ; Skin Diseases/chemically induced ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
    Chemical Substances Antirheumatic Agents ; Tumor Necrosis Factor-alpha ; Etanercept (OP401G7OJC)
    Language English
    Publishing date 2016-11
    Publishing country Brazil
    Document type Case Reports
    ZDB-ID 2027973-5
    ISSN 1806-9282 ; 0104-4230
    ISSN (online) 1806-9282
    ISSN 0104-4230
    DOI 10.1590/1806-9282.62.08.718
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Possibly drug-induced palpable migratory arciform erythema.

    Dantas, Fernando Luiz Teixeira / Valente, Neusa Yuriko Sakai / Veronez, Isis Suga / Kakizaki, Priscila / Leitão, Juliana Ribeiro / Fraga, Rafael Cavanellas

    Anais brasileiros de dermatologia

    2015  Volume 90, Issue 3 Suppl 1, Page(s) 77–80

    Abstract: Palpable migratory arciform erythema is an entity of unknown etiology, with few published cases in the literature. The clinical and histopathological features of this disease are difficult to be distinguished from those of Jessner's lymphocytic ... ...

    Abstract Palpable migratory arciform erythema is an entity of unknown etiology, with few published cases in the literature. The clinical and histopathological features of this disease are difficult to be distinguished from those of Jessner's lymphocytic infiltration of the skin, lupus erythematous tumidus and the deep erythema annulare centrifugum. We describe here the first two Brazilian cases of palpable migratory arciform erythema. The patients presented with infiltrated annular plaques and erythematous arcs without scales. These showed centrifugal growth before disappearing without scarring or residual lesions after a few days. They had a chronic course with repeated episodes for years. In addition, these cases provide evidence of a drug-induced etiology.
    MeSH term(s) Biopsy ; Brazil ; Drug Eruptions/pathology ; Erythema/chemically induced ; Erythema/pathology ; Female ; Humans ; Middle Aged ; Pseudolymphoma/chemically induced ; Pseudolymphoma/pathology ; Skin/pathology ; T-Lymphocytes/pathology ; Time Factors
    Language English
    Publishing date 2015-07-29
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/abd1806-4841.20153624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with etanercept

    Marcella Amaral Horta Barbosa Vieira / Maria Isabel Ramos Saraiva / Larissa Karine Leite da Silva / Rafael Cavanellas Fraga / Priscila Kakizaki / Neusa Yuriko Sakai Valente

    Revista da Associação Médica Brasileira, Vol 62, Iss 8, Pp 718-720

    Abstract: Summary We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative ... ...

    Abstract Summary We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for fungi and acid-fast bacilli (AFB). After discontinuation of etanercept, the patient's condition improved. Although apparently paradoxical, cases of cutaneous and systemic sarcoidosis after anti-TNF medications have been reported in the literature, with very few cases presenting exclusive cutaneous involvement.
    Keywords sarcoidose ; fator de necrose tumoral alfa ; doença granulomatosa crônica ; artrite reumatoide ; Medicine (General) ; R5-920
    Language English
    Publisher Associação Médica Brasileira
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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