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  1. Article: A comparison between the preferences for oral corrective feedback of teachers and students of Chinese as a second language.

    Bao, Rui / Wang, Hui

    Frontiers in psychology

    2023  Volume 14, Page(s) 1112136

    Abstract: This study reports on the preferences of teachers and students of Chinese as a second language (CSL) for corrective feedback ( ...

    Abstract This study reports on the preferences of teachers and students of Chinese as a second language (CSL) for corrective feedback (
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1112136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Comparative Study on the Distribution Pattern of Endocrine Cells in the Gastrointestinal Tract of Two Small Alpine Mammals, Plateau Zokor (

    Cai, Xincheng / Bao, Darhan / Hua, Rui / Cai, Bin / Wang, Lei / Dong, Rui / Hua, Limin

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 4

    Abstract: Endocrine cells can secrete a variety of gastrointestinal hormones that regulate gastrointestinal digestion and absorption, which, in turn, play an important role in animal growth, metabolism, and acclimation. The small alpine mammals, plateau zokor ( ...

    Abstract Endocrine cells can secrete a variety of gastrointestinal hormones that regulate gastrointestinal digestion and absorption, which, in turn, play an important role in animal growth, metabolism, and acclimation. The small alpine mammals, plateau zokor (
    Language English
    Publishing date 2023-02-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13040640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications.

    Shi, Meng / Nan, Xin-Rui / Liu, Bao-Qin

    International journal of molecular sciences

    2024  Volume 25, Issue 2

    Abstract: FUT8, the sole glycosyltransferase responsible for N-glycan core fucosylation, plays a crucial role in tumorigenesis and development. Aberrant FUT8 expression disrupts the function of critical cellular components and triggers the abnormality of tumor ... ...

    Abstract FUT8, the sole glycosyltransferase responsible for N-glycan core fucosylation, plays a crucial role in tumorigenesis and development. Aberrant FUT8 expression disrupts the function of critical cellular components and triggers the abnormality of tumor signaling pathways, leading to malignant transformations such as proliferation, invasion, metastasis, and immunosuppression. The association between FUT8 and unfavorable outcomes in various tumors underscores its potential as a valuable diagnostic marker. Given the remarkable variation in biological functions and regulatory mechanisms of FUT8 across different tumor types, gaining a comprehensive understanding of its complexity is imperative. Here, we review how FUT8 plays roles in tumorigenesis and development, and how this outcome could be utilized to develop potential clinical therapies for tumors.
    MeSH term(s) Humans ; Carcinogenesis/genetics ; Cell Transformation, Neoplastic/genetics ; Immunosuppression Therapy ; Fucosyltransferases/genetics
    Chemical Substances Glycoprotein 6-alpha-L-fucosyltransferase (EC 2.4.1.68) ; Fucosyltransferases (EC 2.4.1.-)
    Language English
    Publishing date 2024-01-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25021068
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  4. Article ; Online: Pig-to-Human xenotransplantation: Moving toward organ customization.

    Gao, Mengyu / Zhang, Jie / Wang, Rui / Yang, Guang / Bao, Ji

    Precision clinical medicine

    2023  Volume 6, Issue 2, Page(s) pbad013

    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2948341-4
    ISSN 2516-1571 ; 2096-5303
    ISSN (online) 2516-1571
    ISSN 2096-5303
    DOI 10.1093/pcmedi/pbad013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: An Update on the Key Factors Required for Plant Golgi Structure Maintenance.

    Rui, Qingchen / Tan, Xiaoyun / Liu, Feng / Bao, Yiqun

    Frontiers in plant science

    2022  Volume 13, Page(s) 933283

    Abstract: Plant Golgi apparatus serves as the central station of the secretory pathway and is the site where protein modification and cell wall matrix polysaccharides synthesis occur. The polarized and stacked cisternal structure is a prerequisite for Golgi ... ...

    Abstract Plant Golgi apparatus serves as the central station of the secretory pathway and is the site where protein modification and cell wall matrix polysaccharides synthesis occur. The polarized and stacked cisternal structure is a prerequisite for Golgi function. Our understanding of Golgi structure maintenance and trafficking are largely obtained from mammals and yeast, yet, plant Golgi has many different aspects. In this review, we summarize the key players in Golgi maintenance demonstrated by genetic studies in plants, which function in ER-Golgi, intra-Golgi and post-Golgi transport pathways. Among these, we emphasize on players in intra-Golgi trafficking.
    Language English
    Publishing date 2022-06-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.933283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Organo-Photocatalytic Anti-Markovnikov Hydroamidation of Alkenes with Sulfonyl Azides: A Combined Experimental and Computational Study.

    Fu, Rui / Xu, Mengyu / Wang, Yujing / Wu, Xinxin / Bao, Xiaoguang

    Angewandte Chemie (International ed. in English)

    2024  , Page(s) e202406069

    Abstract: The construction of C(sp3)-N bonds via direct N-centered radical addition with olefins under benign conditions is a desirable but challenging strategy. Herein, we describe an organo-photocatalytic approach to achieve anti-Markovnikov alkene ... ...

    Abstract The construction of C(sp3)-N bonds via direct N-centered radical addition with olefins under benign conditions is a desirable but challenging strategy. Herein, we describe an organo-photocatalytic approach to achieve anti-Markovnikov alkene hydroamidation with sulfonyl azides in a highly efficient manner under transition-metal-free and mild conditions. A broad range of substrates, including both activated and unactivated alkenes, are suitable for this protocol, providing a convenient and practical method to construct sulfonylamide derivatives. A synergistic experimental and computational mechanistic study suggests that the additive, Hantzsch ester (HE), might undergo a triplet-triplet energy transfer manner to achieve photosensitization by the organo-photocatalyst under visible light irradiation. Next, the resulted triplet excited state 3HE* could lead to a homolytic cleavage of C4-H bond, which triggers a straightforward H-atom transfer (HAT) style in converting sulfonyl azide to the corresponding key amidyl radical. Subsequently, radical addition of the amidyl radical to alkenes followed by HAT from p-toluenethiol could proceed to afford the desired anti-Markovnikov hydroamidation product. It is worth noting that mechanistic pathway bifurcation could be possible for this reaction. A feasible radical chain propagation mechanistic pathway is also proposed to rationalize the high efficiency of this reaction.
    Language English
    Publishing date 2024-04-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202406069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Elevated levels of loneliness in migrant children compared to nonmigrant children in urban China: a systematic review and meta-analysis of comparative studies.

    Ge, Lin-Feng / Wu, Rui-Yao / Zhong, Bao-Liang

    Current opinion in psychiatry

    2024  Volume 37, Issue 3, Page(s) 162–171

    Abstract: Purpose of review: About one in four children in China is a migrant child. This population has a higher risk of experiencing loneliness. However, existing studies present conflicting findings regarding the levels of loneliness among migrant children as ... ...

    Abstract Purpose of review: About one in four children in China is a migrant child. This population has a higher risk of experiencing loneliness. However, existing studies present conflicting findings regarding the levels of loneliness among migrant children as compared to local urban children in urban China. This review performs a meta-analysis of studies comparing loneliness levels between these two groups.
    Recent findings: A literature search of major Chinese- and English-language databases revealed 27 eligible comparative studies. These studies reported the means and standardized deviations of loneliness scores for both migrant and nonmigrant children in urban China. Meta-analysis results showed that migrant children experienced significantly higher levels of loneliness than their urban nonmigrant counterparts [standardized mean difference (SMD) = 0.21, P  < 0.001]. Subgroup analysis revealed that studies enrolling migrant children from migrant children's schools had significantly higher pooled SMDs than those enrolling children from public schools (0.346 vs. 0.120, P  = 0.047).
    Summary: Migrant children in urban China experience higher levels of loneliness compared to their local urban peers. Efforts to create a socially inclusive, migrant-friendly environment and reduce social isolation among migrant children are crucial to help alleviate their feelings of loneliness.
    MeSH term(s) Child ; Humans ; Transients and Migrants ; Loneliness ; Schools ; China/epidemiology
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 645162-7
    ISSN 1473-6578 ; 0951-7367
    ISSN (online) 1473-6578
    ISSN 0951-7367
    DOI 10.1097/YCO.0000000000000933
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2532: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Safety of Three-Dimensional Conformal Radiotherapy on the Sheep with Pulmonary Cystic Echinococcosis: A Preliminary Study.

    Zhang, Yuefen / Lu, Pengfei / Qi, Hongzhi / Mao, Rui / Bao, Yongxing

    Acta parasitologica

    2024  Volume 69, Issue 1, Page(s) 559–566

    Abstract: Purpose: Radiotherapy showed the potential to effectively kill the cysts of pulmonary cystic echinococcosis (CE). However, little is known about its safety. This study was designed to investigate the safety of three-dimensional conformal radiotherapy ( ... ...

    Abstract Purpose: Radiotherapy showed the potential to effectively kill the cysts of pulmonary cystic echinococcosis (CE). However, little is known about its safety. This study was designed to investigate the safety of three-dimensional conformal radiotherapy (3D-CRT) on the normal lung tissue adjacent to the cyst and blood of sheep naturally infected with pulmonary CE.
    Methods: Twenty pulmonary CE sheep were randomly divided into control group (n = 5) and radiation groups with a dose of 30 Gray (Gy) (n = 5), 45 Gy (n = 5), and 60 Gy (n = 5), respectively. Animals in control group received no radiation. Heat shock protein 70 (Hsp70), tumor growth factor-β (TGF-β), matrix metalloproteinase-2 (MMP-2) and MMP-9 in the lung tissues adjacent to the cysts, which were considered to be closely related to the pathogenesis of CE, were evaluated after 3D-CRT. A routine blood test was conducted.
    Results: The results showed that there were multiple cysts of various sizes with protoscoleces in the lung tissues of sheep, and necrotic cysts were found after 3D-CRT. 3D-CRT significantly increased the mRNA level of Hsp70, enhanced the protein level of TGF-β and slightly increased the expression of MMP-2 and MMP-9 in lung tissues adjacent to the cysts. 3D-CRT did not significantly alter the amount of WBC, HB and PLT in sheep blood.
    Conclusions: The results suggested that 3D-CRT may suppress the inflammation and induce less damage of the normal lung tissues and blood. We preliminarily showed that 3D-CRT under a safe dose may be used to treat pulmonary CE.
    MeSH term(s) Animals ; Sheep ; Radiotherapy, Conformal/adverse effects ; Radiotherapy, Conformal/methods ; Lung/parasitology ; Lung/radiation effects ; Lung/pathology ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; Echinococcosis, Pulmonary/veterinary ; Sheep Diseases/parasitology ; Transforming Growth Factor beta/blood ; Transforming Growth Factor beta/metabolism ; Transforming Growth Factor beta/genetics ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase 9/blood ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 2/genetics
    Chemical Substances HSP70 Heat-Shock Proteins ; Transforming Growth Factor beta ; Matrix Metalloproteinase 9 (EC 3.4.24.35) ; Matrix Metalloproteinase 2 (EC 3.4.24.24)
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1132735-2
    ISSN 1896-1851 ; 0065-1478 ; 1230-2821
    ISSN (online) 1896-1851
    ISSN 0065-1478 ; 1230-2821
    DOI 10.1007/s11686-023-00751-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.224: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Modular access to alkylgermanes via reductive germylative alkylation of activated olefins under nickel catalysis.

    Gu, Rui / Feng, Xiujuan / Bao, Ming / Zhang, Xuan

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 7669

    Abstract: Carbon-introducing difunctionalization of C-C double bonds enabled by transition-metal catalysis is one of most straightforward and efficient strategies to construct C-C and C-X bonds concurrently from readily available feedstocks towards structurally ... ...

    Abstract Carbon-introducing difunctionalization of C-C double bonds enabled by transition-metal catalysis is one of most straightforward and efficient strategies to construct C-C and C-X bonds concurrently from readily available feedstocks towards structurally diverse molecules in one step; however, analogous difunctionalization for introducing germanium group and other functionalities remains elusive. Herein, we describe a nickel-catalyzed germylative alkylation of activated olefins with easily accessible primary, secondary and tertiary alkyl bromides and chlorogermanes as the electrophiles to form C-Ge and C-C
    Language English
    Publishing date 2023-11-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-43561-z
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  10. Article ; Online: Comparative analysis of five type II TA systems identified in

    Song, Yingjie / Tang, Hong / Bao, Rui

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1127786

    Abstract: Background: Pseudomonas aeruginosa: Methods: We here investigated the diversity and function of five genomic type II TA systems widely distributed among : Results: ParDE, PA1030/PA1029, and HigBA could modulate persister cell formation under ... ...

    Abstract Background: Pseudomonas aeruginosa
    Methods: We here investigated the diversity and function of five genomic type II TA systems widely distributed among
    Results: ParDE, PA1030/PA1029, and HigBA could modulate persister cell formation under treatment with specific antibiotics. Furthermore, cell-based transcriptional and invasion assays revealed that PA1030/PA1029 and HigBA TA systems were critical for intracellular survival.
    Discussion: Our results highlight the prevalence and diverse roles of type II TA systems in
    MeSH term(s) Humans ; Pseudomonas aeruginosa/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Lung/metabolism ; Bacterial Toxins/genetics ; Bacterial Toxins/metabolism ; Toxin-Antitoxin Systems/genetics ; Pseudomonas Infections/microbiology
    Chemical Substances Anti-Bacterial Agents ; Bacterial Toxins
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1127786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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