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  1. Article ; Online: CORR Insights®: What Are the Complication Rates and Factors Associated With Total Femur Replacement After Tumor Resection? Findings From the Japanese Musculoskeletal Oncology Group.

    Damron, Timothy A

    Clinical orthopaedics and related research

    2023  Volume 482, Issue 4, Page(s) 713–715

    MeSH term(s) Humans ; Japan/epidemiology ; Femur/surgery ; Lower Extremity ; Replantation ; Neoplasms/surgery
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000002915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: CORR Insights®: Are Pathologic Fractures in Patients With Osteosarcoma Associated With Worse Survival Outcomes? A Systematic Review and Meta-analysis.

    Damron, Timothy A

    Clinical orthopaedics and related research

    2023  Volume 481, Issue 12, Page(s) 2444–2446

    MeSH term(s) Humans ; Bone Neoplasms/complications ; Bone Neoplasms/therapy ; Fractures, Spontaneous/etiology ; Fractures, Spontaneous/surgery ; Osteosarcoma/therapy ; Prognosis
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000002806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: CORR Insights®: Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.

    Damron, Timothy A

    Clinical orthopaedics and related research

    2022  Volume 481, Issue 1, Page(s) 117–119

    MeSH term(s) Humans ; Giant Cell Tumor of Tendon Sheath ; Aminopyridines ; Pyrroles ; Pain
    Chemical Substances pexidartinib (6783M2LV5X) ; Aminopyridines ; Pyrroles
    Language English
    Publishing date 2022-10-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000002451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Role of Surveillance in Predicting Fracture in Pediatric Patients With Incidentally Discovered Nonossifying Fibromas and Fibrous Cortical Defects: Is It Worth It?

    Patel, Rohan R / Damron, Timothy A

    Journal of pediatric orthopedics

    2024  

    Abstract: Background: Nonossifying fibroma (NOF) and fibrous cortical defect (FCDs), the most common benign pediatric bone lesions, are usually incidental x-ray findings. Surveillance of characteristic lesions has been recommended to monitor for enlargement and ... ...

    Abstract Background: Nonossifying fibroma (NOF) and fibrous cortical defect (FCDs), the most common benign pediatric bone lesions, are usually incidental x-ray findings. Surveillance of characteristic lesions has been recommended to monitor for enlargement and assess fracture risk. However, no accepted fracture risk prediction guidelines exist, so indications for prophylactic surgery are unclear. The study's purposes were to (1) characterize the timing of NOF/FCD-associated fractures, (2) quantify the resources devoted to surveillance, and (3) evaluate the potential for surveillance to prevent pathologic fracture.
    Methods: A single institution retrospective review was conducted to identify pediatric patients (below 18 y old) with clinical-radiographic documentation of an NOF or FCD diagnosis from 2012 to 2020. Patients who presented with fracture were tallied but excluded from the surveillance analysis. Patients without at least one follow-up visit were also excluded. Lesional radiographic features were characterized on initial imaging. The number of visits and imaging studies devoted to surveillance were tabulated. The number of fractures and prophylactic surgeries were recorded to quantify the potential of surveillance to prevent pathologic fractures.
    Results: The study population presenting without fracture consisted of 301 patients with 364 lesions with a mean follow-up of 20 months. By contrast, over the same period, 38 patients presented with NOF/FCD associated pathologic fractures. Surveillance included 1037 additional imaging tests over 1311 follow-up visits, or on average, 3.4 imaging studies and 4.4 visits per patient. During surveillance, only 2 (0.55%) lesions fractured. Another 10/364 (2.8%) patients underwent curettage and grafting, suggesting that-at best-the potential for preventing pathologic fracture by surveillance, assuming all 10 patients who underwent surgery would have subsequently fractured along with the 2 documented fractures, is 3.3% of lesions (12/364).
    Conclusions: The small number of fractures and surgeries during the follow-up period probably does not justify additional resources for surveillance beyond the initial visit, except in symptomatic patients with large lesions. However, subsequent visits may play a role in educating patients and their families regarding the natural history of these lesions.
    Level of evidence: Prognostic Level II-retrospective study.
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604642-3
    ISSN 1539-2570 ; 0271-6798
    ISSN (online) 1539-2570
    ISSN 0271-6798
    DOI 10.1097/BPO.0000000000002666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: CORR Insights®: Does Local Zoledronate Applied to Pasteurized Bone Autografts Improve the Likelihood of Union of Graft-Host Junctions after Limb-sparing Surgery?

    Damron, Timothy A

    Clinical orthopaedics and related research

    2021  Volume 480, Issue 1, Page(s) 121–123

    MeSH term(s) Autografts ; Bone Neoplasms ; Bone Transplantation ; Humans ; Osteosarcoma ; Zoledronic Acid
    Chemical Substances Zoledronic Acid (6XC1PAD3KF)
    Language English
    Publishing date 2021-09-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000001984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Shoulder Pseudo-Tumor from COVID-19 Vaccine.

    Abbas, Anas M / Damron, Timothy A

    Vaccines

    2023  Volume 11, Issue 4

    Abstract: Hypersensitivity reactions to the COVID-19 mRNA vaccines were identified in the initial 2020 trials. Appearance of a soft tissue mass is a rare manifestation of this hypersensitivity reaction. In this patient, bilateral injections resulted in the ... ...

    Abstract Hypersensitivity reactions to the COVID-19 mRNA vaccines were identified in the initial 2020 trials. Appearance of a soft tissue mass is a rare manifestation of this hypersensitivity reaction. In this patient, bilateral injections resulted in the appearance of shoulder masses. Magnetic resonance imaging showed localized pseudo-tumorous edema in both shoulders, one subcutaneous and the other intramuscular. This is only the second case of a mass-like reaction to the COVID-19 vaccine mimicking a possible soft tissue neoplasm. Improper vaccination administration technique may have contributed to this complication. The case is presented to increase awareness of this potential pseudotumor.
    Language English
    Publishing date 2023-04-04
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11040793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Right Biceps Pseudo-Tumor from COVID-19 Vaccination.

    Abbas, Anas M / Caicedo, Martha L / Damron, Timothy A

    Vaccines

    2024  Volume 12, Issue 2

    Abstract: Delayed hypersensitivity reactions (DHRs) have been reported in association with COVID-19 vaccines, particularly those that are mRNA-based. Classic DHRs result in induration, erythema, tenderness, and urticaria. However, soft tissue mass is an uncommon ... ...

    Abstract Delayed hypersensitivity reactions (DHRs) have been reported in association with COVID-19 vaccines, particularly those that are mRNA-based. Classic DHRs result in induration, erythema, tenderness, and urticaria. However, soft tissue mass is an uncommon complication of a COVID-19 vaccination-associated DHR and is rarely reported in the literature. We present a case of a 49-year-old male who recognized a mildly painful, firm soft tissue mass within the biceps mimicking neoplasm six months after receiving the booster dose of the Moderna vaccine. Non-operative conservative treatment modalities, including heating pads, ice packs, acetaminophen, and ibuprofen, failed to improve the patient's mass. The mass, which proved histologically to be an inflammatory pseudo-tumor, did not recur after complete excision. While there have been many reported cases of DHRs following COVID-19 vaccinations, we present this case to raise awareness of the development of pseudo-tumors as a possible, yet rare, clinical manifestation of DHRs following vaccination.
    Language English
    Publishing date 2024-02-03
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines12020160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: CORR Insights®: Can a Novel Scoring System Improve on the Mirels Score in Predicting the Fracture Risk in Patients with Multiple Myeloma?

    Damron, Timothy A

    Clinical orthopaedics and related research

    2020  Volume 479, Issue 3, Page(s) 531–533

    MeSH term(s) Fractures, Bone ; Fractures, Spontaneous ; Humans ; Multiple Myeloma/diagnosis ; Multiple Myeloma/epidemiology
    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000001373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: CORR Insights®: Radiation Disrupts Protective Function of the Spinal Meninges in a Mouse Model of Tumor-induced Spinal Cord Compression.

    Damron, Timothy A

    Clinical orthopaedics and related research

    2020  Volume 479, Issue 1, Page(s) 177–179

    MeSH term(s) Animals ; Disease Models, Animal ; Meninges ; Mice ; Neoplasms ; Spinal Cord Compression/etiology
    Language English
    Publishing date 2020-11-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000001544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: CORR Insights®: Is Treatment with Denosumab Associated with Local Recurrence in Patients with Giant Cell Tumor of Bone Treated with Curettage? A Systematic Review.

    Damron, Timothy A

    Clinical orthopaedics and related research

    2020  Volume 478, Issue 5, Page(s) 1086–1088

    MeSH term(s) Bone Neoplasms/drug therapy ; Bone Neoplasms/surgery ; Curettage ; Denosumab/adverse effects ; Giant Cell Tumor of Bone/diagnostic imaging ; Giant Cell Tumor of Bone/drug therapy ; Giant Cell Tumor of Bone/surgery ; Humans ; Neoplasm Recurrence, Local
    Chemical Substances Denosumab (4EQZ6YO2HI)
    Language English
    Publishing date 2020-03-17
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
    DOI 10.1097/CORR.0000000000001217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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