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  1. Article ; Online: Tribute to Margaret Comerford Freda.

    Simpson, Kathleen Rice

    MCN. The American journal of maternal child nursing

    2015  Volume 40, Issue 6, Page(s) 343

    MeSH term(s) History, 21st Century ; Humans ; Neonatal Nursing/history ; Periodicals as Topic/history ; United States
    Language English
    Publishing date 2015-11
    Publishing country United States
    Document type Biography ; Editorial ; Historical Article
    ZDB-ID 605601-5
    ISSN 1539-0683 ; 0361-929X
    ISSN (online) 1539-0683
    ISSN 0361-929X
    DOI 10.1097/NMC.0000000000000192
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1909: Show issues Location:
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  2. Article ; Online: Seeing a Tree Within the Forest: Selective Detection and Function of Somatodendritic Cholecystokinin Release From Dopamine Neurons in the Ventral Tegmental Area.

    Rice, Margaret E

    Biological psychiatry

    2022  Volume 93, Issue 2, Page(s) 110–112

    MeSH term(s) Cholecystokinin ; Dopaminergic Neurons ; Ventral Tegmental Area
    Chemical Substances Cholecystokinin (9011-97-6)
    Language English
    Publishing date 2022-12-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2022.11.001
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    Zs.A 720: Show issues Location:
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  3. Article ; Online: Closing in on what motivates motivation.

    Rice, Margaret E

    Nature

    2019  Volume 570, Issue 7759, Page(s) 40–42

    MeSH term(s) Dopamine ; Learning ; Motivation
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2019-05-27
    Publishing country England
    Document type News ; Comment
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-019-01589-6
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    Zs.MO 244: Show issues

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  4. Article ; Online: Actions and Consequences of Insulin in the Striatum.

    Patel, Jyoti C / Carr, Kenneth D / Rice, Margaret E

    Biomolecules

    2023  Volume 13, Issue 3

    Abstract: Insulin crosses the blood-brain barrier to enter the brain from the periphery. In the brain, insulin has well-established actions in the hypothalamus, as well as at the level of mesolimbic dopamine neurons in the midbrain. Notably, insulin also acts in ... ...

    Abstract Insulin crosses the blood-brain barrier to enter the brain from the periphery. In the brain, insulin has well-established actions in the hypothalamus, as well as at the level of mesolimbic dopamine neurons in the midbrain. Notably, insulin also acts in the striatum, which shows abundant expression of insulin receptors (InsRs) throughout. These receptors are found on interneurons and striatal projections neurons, as well as on glial cells and dopamine axons. A striking functional consequence of insulin elevation in the striatum is promoting an increase in stimulated dopamine release. This boosting of dopamine release involves InsRs on cholinergic interneurons, and requires activation of nicotinic acetylcholine receptors on dopamine axons. Opposing this dopamine-enhancing effect, insulin also increases dopamine uptake through the action of insulin at InsRs on dopamine axons. Insulin acts on other striatal cells as well, including striatal projection neurons and astrocytes that also influence dopaminergic transmission and striatal function. Linking these cellular findings to behavior, striatal insulin signaling is required for the development of flavor-nutrient learning, implicating insulin as a reward signal in the brain. In this review, we discuss these and other actions of insulin in the striatum, including how they are influenced by diet and other physiological states.
    MeSH term(s) Acetylcholine/metabolism ; Cholinergic Agents/metabolism ; Corpus Striatum/metabolism ; Dopamine/metabolism ; Insulin/metabolism ; Receptor, Insulin/metabolism
    Chemical Substances Acetylcholine (N9YNS0M02X) ; Cholinergic Agents ; Dopamine (VTD58H1Z2X) ; Insulin ; Receptor, Insulin (EC 2.7.10.1)
    Language English
    Publishing date 2023-03-11
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom13030518
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  5. Article ; Online: Monitoring Molecules in Neuroscience Then and Now.

    Rice, Margaret E

    ACS chemical neuroscience

    2017  Volume 8, Issue 2, Page(s) 215–217

    Abstract: The 16th International Conference on Monitoring Molecules in Neuroscience (MMiN) was held in Gothenburg, Sweden in late spring 2016. This conference originated as a methods meeting focused on in vivo voltammetric techniques and microdialysis. Over time, ... ...

    Abstract The 16th International Conference on Monitoring Molecules in Neuroscience (MMiN) was held in Gothenburg, Sweden in late spring 2016. This conference originated as a methods meeting focused on in vivo voltammetric techniques and microdialysis. Over time, however, the scope has evolved to include a number of other methods for neurochemical detection that range from single-cell fluorescence in vitro and in vivo in animal models to whole-brain imaging in humans. Overall, MMiN provides a unique forum for introducing new developments in neurochemical detection, as well as for reporting exciting neurobiological insights provided by established and novel methods. This Viewpoint includes a brief history of the meeting, factors that have contributed its evolution, and some highlights of MMiN 2016.
    MeSH term(s) Environmental Monitoring ; History, 20th Century ; History, 21st Century ; Humans ; Neurosciences/history ; Neurosciences/trends
    Language English
    Publishing date 2017-02-07
    Publishing country United States
    Document type Historical Article ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.7b00043
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  6. Article ; Online: Toward robust quantification of dopamine and serotonin in mixtures using nano-graphitic carbon sensors.

    Jamalzadeh, Moeid / Cuniberto, Edoardo / Huang, Zhujun / Feeley, Ryan M / Patel, Jyoti C / Rice, Margaret E / Uichanco, Joline / Shahrjerdi, Davood

    The Analyst

    2024  Volume 149, Issue 8, Page(s) 2351–2362

    Abstract: Monitoring the coordinated signaling of dopamine (DA) and serotonin (5-HT) is important for advancing our understanding of the brain. However, the co-detection and robust quantification of these signals at low concentrations is yet to be demonstrated. ... ...

    Abstract Monitoring the coordinated signaling of dopamine (DA) and serotonin (5-HT) is important for advancing our understanding of the brain. However, the co-detection and robust quantification of these signals at low concentrations is yet to be demonstrated. Here, we present the quantification of DA and 5-HT using nano-graphitic (NG) sensors together with fast-scan cyclic voltammetry (FSCV) employing an engineered N-shape potential waveform. Our method yields 6% error in quantifying DA and 5-HT analytes present in
    MeSH term(s) Dopamine ; Carbon ; Serotonin ; Carbon Fiber ; Graphite ; Microelectrodes ; Electrochemical Techniques/methods
    Chemical Substances Dopamine (VTD58H1Z2X) ; Carbon (7440-44-0) ; Serotonin (333DO1RDJY) ; Carbon Fiber ; Graphite (7782-42-5)
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an02086j
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    Zs.A 2423: Show issues Location:
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  7. Article ; Online: The Game of Queer Family Life: Exploring 2SLGBTQI+ Parents' Experiences of Cisheteronormativity, Racism, and Colonialism Through Digital Storytelling in Ontario, Canada.

    Gruson-Wood, Julia F / Reid, Kael / Rice, Carla / Haines, Jess / Chapman, Gwen E / Gibson, Margaret F

    Journal of homosexuality

    2022  Volume 71, Issue 4, Page(s) 887–915

    Abstract: In this article we describe and analyze five videos created through an arts-informed research project, ...

    Abstract In this article we describe and analyze five videos created through an arts-informed research project,
    MeSH term(s) Humans ; Ontario ; Racism ; Colonialism ; Sexual and Gender Minorities ; Parents/psychology
    Language English
    Publishing date 2022-12-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193138-6
    ISSN 1540-3602 ; 0091-8369
    ISSN (online) 1540-3602
    ISSN 0091-8369
    DOI 10.1080/00918369.2022.2132581
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    Zs.A 1141: Show issues Location:
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  8. Article ; Online: Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release.

    Hikima, Takuya / Witkovsky, Paul / Khatri, Latika / Chao, Moses V / Rice, Margaret E

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    2022  Volume 42, Issue 19, Page(s) 3919–3930

    Abstract: The molecular mechanisms underlying somatodendritic dopamine (DA) release remain unresolved, despite the passing of decades since its discovery. Our previous work showed robust release of somatodendritic DA in submillimolar extracellular ... ...

    Abstract The molecular mechanisms underlying somatodendritic dopamine (DA) release remain unresolved, despite the passing of decades since its discovery. Our previous work showed robust release of somatodendritic DA in submillimolar extracellular Ca
    MeSH term(s) Animals ; Dendrites ; Dopamine/pharmacology ; Dopaminergic Neurons ; Electric Stimulation ; Female ; Male ; Mice ; Substantia Nigra ; Synaptotagmin I/genetics ; Synaptotagmins/genetics
    Chemical Substances Synaptotagmin I ; Syt1 protein, mouse ; Syt7 protein, mouse ; Synaptotagmins (134193-27-4) ; Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604637-x
    ISSN 1529-2401 ; 0270-6474
    ISSN (online) 1529-2401
    ISSN 0270-6474
    DOI 10.1523/JNEUROSCI.2416-21.2022
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    Zs.A 1668: Show issues Location:
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  9. Article ; Online: GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABA

    Patel, Jyoti C / Sherpa, Ang D / Melani, Riccardo / Witkovsky, Paul / Wiseman, Madeline R / O'Neill, Brian / Aoki, Chiye / Tritsch, Nicolas X / Rice, Margaret E

    Cell reports

    2024  Volume 43, Issue 3, Page(s) 113834

    Abstract: Striatal dopamine axons co-release dopamine and gamma-aminobutyric acid (GABA), using GABA provided by uptake via GABA transporter-1 (GAT1). Functions of GABA co-release are poorly understood. We asked whether co-released GABA autoinhibits dopamine ... ...

    Abstract Striatal dopamine axons co-release dopamine and gamma-aminobutyric acid (GABA), using GABA provided by uptake via GABA transporter-1 (GAT1). Functions of GABA co-release are poorly understood. We asked whether co-released GABA autoinhibits dopamine release via axonal GABA type A receptors (GABA
    MeSH term(s) Mice ; Animals ; Dopamine ; Autoreceptors ; gamma-Aminobutyric Acid/pharmacology ; Axons/metabolism ; Corpus Striatum/metabolism ; Receptors, GABA-A/metabolism ; Mice, Knockout ; Homeostasis
    Chemical Substances Dopamine (VTD58H1Z2X) ; Autoreceptors ; gamma-Aminobutyric Acid (56-12-2) ; Receptors, GABA-A
    Language English
    Publishing date 2024-03-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2024.113834
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  10. Article: Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival.

    Kachuri, Linda / Guerra, Geno A / Wendt, George A / Hansen, Helen M / Molinaro, Annette M / Bracci, Paige / McCoy, Lucie / Rice, Terri / Wiencke, John K / Eckel-Passow, Jeanette E / Jenkins, Robert B / Wrensch, Margaret / Francis, Stephen S

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: Glioma is a highly fatal brain tumor comprised of molecular subtypes with distinct clinical trajectories. Observational studies have suggested that variability in immune response may play a role in glioma etiology. However, their findings have been ... ...

    Abstract Glioma is a highly fatal brain tumor comprised of molecular subtypes with distinct clinical trajectories. Observational studies have suggested that variability in immune response may play a role in glioma etiology. However, their findings have been inconsistent and susceptible to reverse causation due to treatment effects and the immunosuppressive nature of glioma. We applied genetic variants associated (p<5×10
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.15.23296448
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