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  1. Book: Depressive Störungen

    Mehler-Wex, Claudia

    mit 30 Tabellen

    (Manuale psychischer Störungen bei Kindern und Jugendlichen)

    2008  

    Author's details Claudia Mehler-Wex
    Series title Manuale psychischer Störungen bei Kindern und Jugendlichen
    Keywords Depressive Disorder ; Child ; Adolescent ; Kind ; Depression ; Jugend
    Subject Depressionen ; Jugend ; Jugendalter ; Jugendlicher ; Teenager ; Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language German
    Size VIII, 207 S. : Ill.
    Publisher Springer
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book
    HBZ-ID HT015675474
    ISBN 978-3-540-68324-7 ; 9783540683278 ; 3-540-68324-0 ; 3540683275
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Multidisziplinäre Zusammenarbeit in der Schematherapie für Adoleszente - Ein Einblick in die praktische Umsetzung

    Bauer, Anja / Mehler-Wex, Claudia / Hamák, Ludwina

    Forum für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie

    2021  Volume 31, Issue 1, Page(s) 58

    Language German
    Document type Article
    ZDB-ID 2266629-1
    ISSN 1867-6677
    Database Current Contents Medicine

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  3. Article: Reifung mit Krisen - Herausforderungen der Adoleszentenpsychiatrie

    Mehler-Wex, Claudia

    Forum für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie

    2017  Volume 27, Issue 4, Page(s) 2

    Language German
    Document type Article
    ZDB-ID 2266629-1
    ISSN 1867-6677 ; 0943-8831
    Database Current Contents Medicine

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  4. Book ; Thesis: Die Rolle der Sulfoxidierung in der geschlechtsspezifischen Nephrotoxizität von Hexachlor-1,3-butadien

    Mehler-Wex, Claudia

    1998  

    Author's details vorgelegt von Claudia Mehler
    Language German
    Size 42 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Würzburg, Univ., Diss., 1999
    HBZ-ID HT011213247
    Database Catalogue ZB MED Medicine, Health

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  5. Conference proceedings: Reifungskrisen: Hintergründe und Behandlungsstrategien

    Mehler-Wex, C.

    2016  , Page(s) 16sgkjPP–28

    Event/congress 65. Jahrestagung der Süddeutschen Gesellschaft für Kinder- und Jugendmedizin gemeinsam mit der Süddeutschen Gesellschaft für Kinderchirurgie und dem Berufsverband der Kinder- und Jugendärzte e.V. – Landesverband Hessen; Süddeutscher Kongress für Kinder- und Jugendmedizin; Bad Nauheim; ; Berufsverband der Kinder- und Jugendärzte e.V. – Landesverband Hessen; 2016
    Keywords Medizin, Gesundheit
    Publishing date 2016-05-06
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/16sgkj47
    Database German Medical Science

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  6. Article: Schematherapie in der Adoleszentenpsychiatrie

    Deimel, Wolfgang / Mehler-Wex, Claudia

    Forum für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie

    2018  Volume 28, Issue 4, Page(s) 36

    Language German
    Document type Article
    ZDB-ID 2266629-1
    ISSN 1867-6677 ; 0943-8831
    Database Current Contents Medicine

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  7. Article: ADHS im Kindes- und Jugendalter. Hilfe für Zappelphilipp und Träumerchen.

    Mehler-Wex, Claudia / Deimel, Wolfgang

    MMW Fortschritte der Medizin

    2014  Volume 156, Issue 14, Page(s) 41–44

    Title translation Attention deficit hyperactivity disorder in children and adolescents.
    MeSH term(s) Adolescent ; Attention Deficit Disorder with Hyperactivity/diagnosis ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Attention Deficit Disorder with Hyperactivity/psychology ; Attention Deficit Disorder with Hyperactivity/therapy ; Behavior Therapy ; Central Nervous System Stimulants/adverse effects ; Central Nervous System Stimulants/therapeutic use ; Child ; Child, Preschool ; Cross-Sectional Studies ; Diagnosis, Differential ; Education, Nonprofessional ; Education, Special ; Germany ; Humans ; International Classification of Diseases ; Personality Assessment ; Risk Factors ; Suicide/prevention & control ; Surveys and Questionnaires
    Chemical Substances Central Nervous System Stimulants
    Language German
    Publishing date 2014-09-05
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1438-3276
    ISSN 1438-3276
    DOI 10.1007/s15006-014-3340-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Correction to: Estimation of a preliminary therapeutic reference range for children and adolescents with tic disorders treated with tiapride.

    Fekete, Stefanie / Egberts, K / Preissler, T / Wewetzer, C / Mehler-Wex, C / Romanos, M / Gerlach, M

    European journal of clinical pharmacology

    2021  Volume 77, Issue 8, Page(s) 1257

    Language English
    Publishing date 2021-05-28
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 121960-1
    ISSN 1432-1041 ; 0031-6970
    ISSN (online) 1432-1041
    ISSN 0031-6970
    DOI 10.1007/s00228-021-03159-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Ganzheitliche Behandlung bei Adoleszentenkrisen. Psychiatrie bei Heranreifenden

    Mehler-Wex, Claudia

    Der Neurologe & Psychiater

    2014  Volume 15, Issue 11, Page(s) 62

    Language German
    Document type Article
    ZDB-ID 2036795-8
    ISSN 1616-2455
    Database Current Contents Medicine

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  10. Article ; Online: Estimation of a preliminary therapeutic reference range for children and adolescents with tic disorders treated with tiapride.

    Fekete, Stefanie / Egberts, K / Preissler, T / Wewetzer, C / Mehler-Wex, C / Romanos, M / Gerlach, M

    European journal of clinical pharmacology

    2020  Volume 77, Issue 2, Page(s) 163–170

    Abstract: Purpose: Tiapride is commonly used in Europe for the treatment of tics. The aim of this study was to examine the relationship between dose and serum concentrations of tiapride and potential influential pharmacokinetic factors in children and adolescents. ...

    Abstract Purpose: Tiapride is commonly used in Europe for the treatment of tics. The aim of this study was to examine the relationship between dose and serum concentrations of tiapride and potential influential pharmacokinetic factors in children and adolescents. In addition, a preliminary therapeutic reference range for children and adolescents with tics treated with tiapride was calculated.
    Methods: Children and adolescents treated with tiapride at three university hospitals and two departments of child and adolescents psychiatry in Germany and Austria were included in the study. Patient characteristics, doses, serum concentrations, and therapeutic outcome were assessed during clinical routine care using standardised measures.
    Results: In the 49 paediatric patients (83.7% male, mean age = 12.5 years), a positive correlation was found between tiapride dose (median 6.9 mg/kg, range 0.97-19.35) and serum concentration with marked inter-individual variability. The variation in dose explained 57% of the inter-patient variability in tiapride serum concentrations; age, gender, and concomitant medication did not contribute to the variability. The symptoms improved in 83.3% of the patients. 27.1% of the patients had mild or moderate ADRs. No patient suffered from severe ADRs.
    Conclusions: This study shows that tiapride treatment was effective and safe in most patients with tics. Compared with the therapeutic concentration range established for adults with Chorea Huntington, our data hinted at a lower lower limit (560 ng/ml) and similar upper limit (2000 ng/ml).
    MeSH term(s) Adolescent ; Age Factors ; Biological Variation, Population ; Child ; Dopamine D2 Receptor Antagonists/pharmacology ; Dopamine D2 Receptor Antagonists/therapeutic use ; Dose-Response Relationship, Drug ; Female ; Humans ; Male ; Prospective Studies ; Reference Values ; Severity of Illness Index ; Sex Factors ; Tiapride Hydrochloride/pharmacology ; Tiapride Hydrochloride/therapeutic use ; Tic Disorders/blood ; Tic Disorders/diagnosis ; Tic Disorders/drug therapy ; Treatment Outcome
    Chemical Substances Dopamine D2 Receptor Antagonists ; Tiapride Hydrochloride (51012-32-9)
    Language English
    Publishing date 2020-09-28
    Publishing country Germany
    Document type Journal Article ; Multicenter Study ; Observational Study
    ZDB-ID 121960-1
    ISSN 1432-1041 ; 0031-6970
    ISSN (online) 1432-1041
    ISSN 0031-6970
    DOI 10.1007/s00228-020-03000-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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