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  1. Article ; Online: Photochemistry and Photophysics of the 3-Styrylidenebenz[e]indanes.

    Saltiel, Jack / Gupta, Shipra / Eaker, David W / Kropp, Andrew M / Kumar, V K Ratheesh

    Photochemistry and photobiology

    2018  Volume 94, Issue 2, Page(s) 247–260

    Abstract: The photochemical and photophysical properties of the extended conformers of trans- and cis-1-(2-naphthyl)-2-phenylethenes (t- and c- ... ...

    Abstract The photochemical and photophysical properties of the extended conformers of trans- and cis-1-(2-naphthyl)-2-phenylethenes (t- and c-NPE
    Language English
    Publishing date 2018-01-03
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 123540-0
    ISSN 1751-1097 ; 0031-8655
    ISSN (online) 1751-1097
    ISSN 0031-8655
    DOI 10.1111/php.12849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Mechanisms of Insulin Action

    Saltiel, Alan R. / Pessin, Jeffrey E.

    Medical Intelligence Unit

    2007  

    Author's details by Alan R. Saltiel, Jeffrey E. Pessin
    Keywords Cardiology ; Cell biology ; Diabetes ; Endocrinology
    Language English
    Publisher Landes Bioscience and Springer Science+Business Media, LLC
    Publishing place New York, NY
    Document type Book ; Online
    HBZ-ID TT050386941
    ISBN 978-0-387-72203-0 ; 978-0-387-72204-7 ; 0-387-72203-3 ; 0-387-72204-1
    DOI 10.1007/978-0-387-72204-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Clostridium difficile-associated diarrhea: role of the pharmacist in the health system.

    Saltiel, Emmanuel

    Journal of pharmacy practice

    2013  Volume 26, Issue 5, Page(s) 462–463

    MeSH term(s) Clostridium Infections/epidemiology ; Clostridium Infections/microbiology ; Clostridium Infections/therapy ; Clostridium difficile/isolation & purification ; Cross Infection/microbiology ; Diarrhea/microbiology ; Diarrhea/therapy ; Humans ; Pharmaceutical Services/organization & administration ; Pharmacists/organization & administration ; Professional Role
    Language English
    Publishing date 2013-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1027474-1
    ISSN 1531-1937 ; 0897-1900
    ISSN (online) 1531-1937
    ISSN 0897-1900
    DOI 10.1177/0897190013499520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Revising the classification of lung sequestrations.

    Alamo, Leonor / Saltiel, Sarah / Tenisch, Estelle

    Clinical imaging

    2021  Volume 77, Page(s) 92–97

    Abstract: Purposes: The classification of lung sequestrations distinguishes between extralobar and intralobar types, according to their venous drainage - systemic vs pulmonary - and the presence or absence of independent pleura. However, imaging, surgical and/or ... ...

    Abstract Purposes: The classification of lung sequestrations distinguishes between extralobar and intralobar types, according to their venous drainage - systemic vs pulmonary - and the presence or absence of independent pleura. However, imaging, surgical and/or pathological findings often differ from this description. The objectives of this article are to quantify the percentage of lung sequestrations that do not fit the classic description of extra- and intralobar types and to evaluate the accuracy of the currently used classification.
    Methods: A retrospective search identified all children with a confirmed lung sequestration diagnosed and treated in our Hospital over the last 10 years. Two senior pediatric radiologists reviewed their contrast-enhanced computed tomography chest scans and evaluated the main anatomical features that define sequestrations, including pleura, arterial and venous pattern, airways and lung parenchyma. We compared the imaging-, surgical- and pathological findings to those described for extra- and intralobar sequestrations.
    Results: 25 children (20 M, 5 F) conform the series. Only 13 lesions (52%) filled all criteria described for an extra- or intralobar sequestration. The remaining 12 lesions (48%) had at least one differing criteria, including incomplete independent pleura (n = 2; 8%), mixed systemic and pulmonary arterial supply (n = 1; 4%) or venous drainage (n = 3; 12%), normal connection to airway (n = 1; 4%) and/or coexistent congenital lung anomalies (n = 11; 44%).
    Conclusion: Lung sequestrations seem to represent a spectrum of anomalies rather than separated entities. Therefore, a detailed description of their main anatomical features could be more relevant for clinicians and surgeons that the rigid distinction in intra- and extralobar sequestration currently applied.
    MeSH term(s) Bronchopulmonary Sequestration/diagnostic imaging ; Bronchopulmonary Sequestration/surgery ; Child ; Humans ; Lung/diagnostic imaging ; Pleura ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2021.02.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Real-life use of letermovir prophylaxis for cytomegalovirus in heart transplant recipients.

    Saltiel, Grégoire / Faure, Emmanuel / Assaf, Ady / Chopin, Marie-Charlotte / Moreau, Fanny / Faure, Karine / Goeminne, Céline / Vuotto, Fanny

    Clinical transplantation

    2024  Volume 38, Issue 5, Page(s) e15327

    Abstract: Introduction: Cytomegalovirus (CMV) remains the predominant opportunistic infection following solid organ transplantation (SOT). While valganciclovir is the drug of choice for CMV prophylaxis, its utility can be compromised due to the risk of cytopenia. ...

    Abstract Introduction: Cytomegalovirus (CMV) remains the predominant opportunistic infection following solid organ transplantation (SOT). While valganciclovir is the drug of choice for CMV prophylaxis, its utility can be compromised due to the risk of cytopenia. Letermovir, a novel agent approved for CMV prophylaxis in allogeneic hematopoietic stem cell transplant recipients and high-risk kidney transplant recipients, exhibits reduced toxicity. This study aims to present the practical application of letermovir as both primary and secondary prophylaxis against CMV in heart transplant recipients (HTR).
    Methods: In this observational, retrospective, single-center study, we included all consecutive adult HTRs from June 2020 to January 2022 who were administered letermovir for CMV prophylaxis. We documented instances of CMV breakthrough infections, side effects related to letermovir, changes in neutropenia following the switch from valganciclovir to letermovir, and any drug interactions with the immunosuppressive regimen.
    Results: The study comprised 10 patients: two received primary prophylaxis with letermovir due to a high risk of CMV infection (donor-positive, recipient-negative serostatus), and eight received it as secondary prophylaxis following a CMV infection. The median duration of letermovir administration was 8 months (range 3-12 months). No CMV breakthrough infections were reported while on prophylaxis. However, three patients experienced CMV breakthrough infections after discontinuing letermovir prophylaxis (30%). No significant side effects were observed, although one patient reported digestive intolerance. Among the nine patients on tacrolimus, six needed reduced doses after switching to letermovir.
    Conclusion: This real-life study appears to support the effectiveness of letermovir prophylaxis in HTR. Nonetheless, the risk of CMV infection post-treatment cessation is notable. Further drug monitoring and research on the efficacy of letermovir for CMV prophylaxis in SOT patients is warranted.
    MeSH term(s) Humans ; Cytomegalovirus Infections/prevention & control ; Cytomegalovirus Infections/etiology ; Heart Transplantation/adverse effects ; Male ; Retrospective Studies ; Antiviral Agents/therapeutic use ; Female ; Middle Aged ; Follow-Up Studies ; Cytomegalovirus/isolation & purification ; Adult ; Aged ; Prognosis ; Acetates/therapeutic use ; Quinazolines/therapeutic use ; Transplant Recipients ; Postoperative Complications/prevention & control ; Risk Factors ; Graft Rejection/prevention & control ; Graft Rejection/etiology
    Chemical Substances letermovir (1H09Y5WO1F) ; Antiviral Agents ; Acetates ; Quinazolines
    Language English
    Publishing date 2024-04-30
    Publishing country Denmark
    Document type Journal Article ; Observational Study
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/ctr.15327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Can ChatGPT Compute Trustworthy Sentiment Scores from Bloomberg Market Wraps?

    Lefort, Baptiste / Benhamou, Eric / Ohana, Jean-Jacques / Saltiel, David / Guez, Beatrice / Challet, Damien

    2024  

    Abstract: We used a dataset of daily Bloomberg Financial Market Summaries from 2010 to 2023, reposted on large financial media, to determine how global news headlines may affect stock market movements using ChatGPT and a two-stage prompt approach. We document a ... ...

    Abstract We used a dataset of daily Bloomberg Financial Market Summaries from 2010 to 2023, reposted on large financial media, to determine how global news headlines may affect stock market movements using ChatGPT and a two-stage prompt approach. We document a statistically significant positive correlation between the sentiment score and future equity market returns over short to medium term, which reverts to a negative correlation over longer horizons. Validation of this correlation pattern across multiple equity markets indicates its robustness across equity regions and resilience to non-linearity, evidenced by comparison of Pearson and Spearman correlations. Finally, we provide an estimate of the optimal horizon that strikes a balance between reactivity to new information and correlation.
    Keywords Quantitative Finance - Statistical Finance ; Computer Science - Artificial Intelligence
    Publishing date 2024-01-09
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Photochemistry and photophysics of cholesta-5,7,9(11)-trien-3β-ol: a fluorescent analogue of cholesterol.

    Saltiel, Jack / Krishnan, Sumesh B / Gupta, Shipra / Hernberg, E Aliea / Clark, Ronald J

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

    2022  Volume 21, Issue 1, Page(s) 37–47

    Abstract: Cholesta-5,7,9(11)-trien-3β-ol (9,11-dehydroprovitamin ... ...

    Abstract Cholesta-5,7,9(11)-trien-3β-ol (9,11-dehydroprovitamin D
    MeSH term(s) Cholesterol ; Crystallography, X-Ray ; Magnetic Resonance Spectroscopy ; Photochemistry ; Trientine
    Chemical Substances Cholesterol (97C5T2UQ7J) ; Trientine (SJ76Y07H5F)
    Language English
    Publishing date 2022-01-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2072584-X
    ISSN 1474-9092 ; 1474-905X
    ISSN (online) 1474-9092
    ISSN 1474-905X
    DOI 10.1007/s43630-021-00131-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: HPV16

    Konstantopoulos, Georgios / Leventakou, Danai / Saltiel, Despoina-Rozi / Zervoudi, Efthalia / Logotheti, Eirini / Pettas, Spyros / Karagianni, Korina / Daiou, Angeliki / Hatzistergos, Konstantinos E / Dafou, Dimitra / Arsenakis, Minas / Kottaridi, Christine

    Viruses

    2024  Volume 16, Issue 1

    Abstract: Human Papillomaviruses have been associated with the occurrence of cervical cancer, the fourth most common cancer that affects women globally, while 70% of cases are caused by infection with the high-risk types HPV16 and HPV18. The integration of these ... ...

    Abstract Human Papillomaviruses have been associated with the occurrence of cervical cancer, the fourth most common cancer that affects women globally, while 70% of cases are caused by infection with the high-risk types HPV16 and HPV18. The integration of these viruses' oncogenes
    MeSH term(s) Female ; Humans ; B7-H1 Antigen/genetics ; Human papillomavirus 16/genetics ; Immune Evasion ; MicroRNAs/genetics ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/virology ; Oncogene Proteins, Viral/genetics
    Chemical Substances B7-H1 Antigen ; MicroRNAs ; MIRN143 microRNA, human ; E6 protein, Human papillomavirus type 16 ; Oncogene Proteins, Viral ; HIF1A protein, human
    Language English
    Publishing date 2024-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v16010113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The photoisomerization of cis,trans-1,2-dideuterio-1,4-diphenyl-1,3-butadiene in solution. No bicycle-pedal.

    Saltiel, Jack / Redwood, Christopher E / V K, Ratheesh Kumar

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

    2019  Volume 18, Issue 9, Page(s) 2174–2179

    Abstract: cis,trans-1,2-Dideuterio-1,4-diphenyl-1,3-butadiene (ct- ... ...

    Abstract cis,trans-1,2-Dideuterio-1,4-diphenyl-1,3-butadiene (ct-DPB
    Language English
    Publishing date 2019-05-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2072584-X
    ISSN 1474-9092 ; 1474-905X
    ISSN (online) 1474-9092
    ISSN 1474-905X
    DOI 10.1039/c9pp00113a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Photochemistry of the 1,4-Diphenyl-1,3-butadienes in Ethanol. Trapping Conical Intersections.

    Saltiel, Jack / Redwood, Christopher E

    The journal of physical chemistry. A

    2016  Volume 120, Issue 18, Page(s) 2832–2840

    Abstract: We report photoisomerization and photoaddition quantum yields in ethanol starting from each 1,4-diphenyl-1,3-butadiene, DPB, isomer. Despite the fact that the trans,trans isomer, tt-DPB, has a significant fluorescence quantum yield and lifetime, whereas ... ...

    Abstract We report photoisomerization and photoaddition quantum yields in ethanol starting from each 1,4-diphenyl-1,3-butadiene, DPB, isomer. Despite the fact that the trans,trans isomer, tt-DPB, has a significant fluorescence quantum yield and lifetime, whereas no fluorescence is observed from the cis isomers, ether formation occurs with similar efficiency from tt-DPB and ct-DPB and less efficiently from cc-DPB. Photoaddition is about 72 times slower than photoisomerization to the ct- and tt-DPB isomers starting from tt- and ct-DPB, respectively. The results are consistent with addition of alcohol to the common zwitterionic trans-phenallyl cation/benzyl anion intermediate that leads to photoisomerization through a conical intersection. Ether formation from cc-DPB tracks inefficient formation of tt-DPB indicating that the small bicycle pedal cc-DPB → tt-DPB component proceeds stepwise through the same zwitterionic trans-phenallyl cation/benzyl anion intermediate. Previous results concerning the addition of methanol to the stilbenes are similarly interpreted. In contrast to trans-stilbene, the fluorescence and photoisomerization quantum yields of tt-DPB are inconsistent with the assumption of strict complementarity between radiative and torsional relaxation channels of tt-DPB in alcohols.
    Language English
    Publishing date 2016--12
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.6b02330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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