LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 77

Search options

  1. Article: Cell-Free DNA: Unveiling the Future of Cancer Diagnostics and Monitoring.

    Francini, Edoardo / Nuzzo, Pier Vitale / Fanelli, Giuseppe Nicolò

    Cancers

    2024  Volume 16, Issue 3

    Abstract: As we conclude this Special Issue of 21 published articles dedicated to cell-free DNA (cfDNA) as a prognostic and predictive biomarker in solid cancers, we find ourselves gazing at a vibrant landscape of research on cfDNA [ ... ]. ...

    Abstract As we conclude this Special Issue of 21 published articles dedicated to cell-free DNA (cfDNA) as a prognostic and predictive biomarker in solid cancers, we find ourselves gazing at a vibrant landscape of research on cfDNA [...].
    Language English
    Publishing date 2024-02-04
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16030662
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Doxycycline or minocycline may be a viable treatment option against SARS-CoV-2.

    Francini, Edoardo / Miano, Salvatora T / Fiaschi, Anna I / Francini, Guido

    Medical hypotheses

    2020  Volume 144, Page(s) 110054

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; COVID-19/drug therapy ; Doxycycline/therapeutic use ; Humans ; Inflammation ; Minocycline/therapeutic use ; Models, Theoretical ; RNA, Double-Stranded/metabolism ; RNA, Ribosomal, 16S/metabolism ; RNA, Viral/metabolism ; Signal Transduction
    Chemical Substances Anti-Bacterial Agents ; RNA, Double-Stranded ; RNA, Ribosomal, 16S ; RNA, Viral ; Minocycline (FYY3R43WGO) ; Doxycycline (N12000U13O)
    Keywords covid19
    Language English
    Publishing date 2020-06-27
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110054
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: A case of eribulin-induced regression of liposarcoma of the left funiculus in a heavily pretreated patient.

    Miano, Salvatora Tindara / Francini, Edoardo / Petrioli, Roberto / Francini, Guido

    Future oncology (London, England)

    2020  Volume 16, Issue 1s, Page(s) 33–38

    Abstract: We report the case of a heavily pretreated male subject affected by left funiculus liposarcoma and successfully treated with eribulin mesylate. After three surgical interventions, radiotherapy on the lesion of the penile bulb for satellite nodules and an ...

    Abstract We report the case of a heavily pretreated male subject affected by left funiculus liposarcoma and successfully treated with eribulin mesylate. After three surgical interventions, radiotherapy on the lesion of the penile bulb for satellite nodules and an epirubicin + ifosfamide chemotherapy treatment for six cycles, eribulin was administered at the dose of 1.1 mg/m
    MeSH term(s) Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Furans/administration & dosage ; Furans/adverse effects ; Furans/therapeutic use ; Genital Neoplasms, Male/diagnosis ; Genital Neoplasms, Male/drug therapy ; Humans ; Ketones/administration & dosage ; Ketones/adverse effects ; Ketones/therapeutic use ; Liposarcoma/diagnosis ; Liposarcoma/drug therapy ; Male ; Retreatment ; Spermatic Cord/pathology ; Tomography, X-Ray Computed ; Treatment Outcome
    Chemical Substances Antineoplastic Agents ; Furans ; Ketones ; eribulin (LR24G6354G)
    Language English
    Publishing date 2020-02-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2019-0600
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6478: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Doxycycline or minocycline may be a viable treatment option against SARS-CoV-2

    Francini, Edoardo / Miano, Salvatora T. / Fiaschi, Anna I. / Francini, Guido

    Medical Hypotheses

    2020  Volume 144, Page(s) 110054

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110054
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Prostate cancer: Developing novel approaches to castration-sensitive disease.

    Francini, Edoardo / Taplin, Mary-Ellen

    Cancer

    2017  Volume 123, Issue 1, Page(s) 29–42

    Abstract: Although androgen-deprivation therapy (ADT) remains the mainstay of castration-sensitive prostate cancer (CSPC) therapy, the disease's heterogeneity and the limited duration of the response have chaperoned the introduction of chemotherapy and the ... ...

    Abstract Although androgen-deprivation therapy (ADT) remains the mainstay of castration-sensitive prostate cancer (CSPC) therapy, the disease's heterogeneity and the limited duration of the response have chaperoned the introduction of chemotherapy and the investigation of novel hormonal targeted agents in this setting. Combinations of ADT plus chemotherapy or novel hormonal therapies are being tested at various stages of CSPC with promising results. Furthermore, immunotherapy and experimental drugs are also being actively investigated in this setting. Intriguing multimodality strategies, chiefly deployed for early-stage disease with the aim of maximizing the efficacy and duration of the response, are being explored and may become valid therapeutic options in the future. Ultimately, striking a balance between the clinical gains of these combinations and possibly increased toxicity and reduced quality of life will be necessary. The development of precision medicine and accurate biomarkers is fundamental to progress. Cancer 2017;29-42. © 2016 American Cancer Society.
    MeSH term(s) Androgen Antagonists/therapeutic use ; Antineoplastic Agents, Hormonal/therapeutic use ; Humans ; Male ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Quality of Life
    Chemical Substances Androgen Antagonists ; Antineoplastic Agents, Hormonal
    Language English
    Publishing date 2017-01-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.30329
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.146: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Docetaxel Activity in the Era of Life-prolonging Hormonal Therapies for Metastatic Castration-resistant Prostate Cancer.

    Francini, Edoardo / Sweeney, Christopher J

    European urology

    2016  Volume 70, Issue 3, Page(s) 410–412

    Abstract: Unlabelled: For >6 yr, docetaxel with prednisone was the only treatment with survival benefits for metastatic castration-resistant prostate cancer (mCRPC). More recently, in clinical practice, abiraterone acetate has been commonly administered prior to ... ...

    Abstract Unlabelled: For >6 yr, docetaxel with prednisone was the only treatment with survival benefits for metastatic castration-resistant prostate cancer (mCRPC). More recently, in clinical practice, abiraterone acetate has been commonly administered prior to docetaxel for the treatment of mCRPC. Our study aimed to review the activity of docetaxel after prior abiraterone. To this end, we analyzed all retrospective reports in the literature describing the overall survival (OS) of mCRPC patients treated with docetaxel after previous abiraterone. The mean OS observed was 12.7 mo, which suggested a significant decrement compared with the 19.2 mo seen in the updated analysis of the TAX 327 study; however, the data are quite similar to the OS of 13.6 mo (95% confidence interval, 12.1-15.1 mo) described in a retrospective single-institution study of 357 men with mCRPC treated with docetaxel with no prior abiraterone mostly in routine practice (86.3%). Because the characteristics of patients recruited in phase 3 trials tend to differ from the real-world setting, we deemed this data set a relevant comparison. Consequently, despite the limitations of retrospective cross-study comparisons, the data suggest that docetaxel retains activity when used as second-line therapy after abiraterone for mCRPC patients.
    Patient summary: We reviewed the activity of docetaxel after prior use of abiraterone and considered the results in the light of the outcomes of docetaxel used as first-line therapy for metastatic castration-resistant prostate cancer (mCRPC) patients in routine practice. We noted that docetaxel retains reasonable activity and is a useful agent for the treatment of mCRPC patients before or after abiraterone.
    Language English
    Publishing date 2016-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2016.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 294: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Bone Metastases in Renal Cell Carcinoma: Impact of Immunotherapy on Survival.

    Gambale, Elisabetta / Palmieri, Valeria Emma / Rossi, Virginia / Francini, Edoardo / Bonato, Adele / Salfi, Alessia / Galli, Luca / Mela, Marinella Micol / Pillozzi, Serena / Antonuzzo, Lorenzo

    Cancer diagnosis & prognosis

    2023  Volume 3, Issue 5, Page(s) 538–542

    Abstract: Background/aim: We performed a multicenter retrospective observational study to investigate the impact of immune checkpoint inhibitors (ICIs) on the survival of patients with bone metastases (BMs) from renal cell cancer (RCC).: Patients and methods: ... ...

    Abstract Background/aim: We performed a multicenter retrospective observational study to investigate the impact of immune checkpoint inhibitors (ICIs) on the survival of patients with bone metastases (BMs) from renal cell cancer (RCC).
    Patients and methods: A total of 98 patients with metastatic RCC (mRCC) treated with ICIs were retrospectively enrolled. All patients received standard treatments with nivolumab alone or in combination with ipilimumab from December 2015 to March 2022. The primary endpoint was median overall survival (OS).
    Results: Forty-three patients (44%) had radiological evidence of BMs. No statistically significant difference in OS was reported between the BM population and the entire population (p=0.254).
    Conclusion: Our study suggests some degree of ICI activity to treat patients with BMs from RCC, historically associated with a poorer prognosis.
    Language English
    Publishing date 2023-09-03
    Publishing country Greece
    Document type Journal Article
    ISSN 2732-7787
    ISSN (online) 2732-7787
    DOI 10.21873/cdp.10252
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Extramammary invasive Paget's disease and apocrine angiomatous hamartoma: an unusual association.

    Miracco, Clelia / Francini, Edoardo / Torre, Pamela / Baldino, Gennaro / Chirra, Martina / Cinotti, Elisa / Francini, Guido

    European journal of dermatology : EJD

    2018  Volume 28, Issue 6, Page(s) 853–855

    MeSH term(s) Apocrine Glands ; Hamartoma/complications ; Hamartoma/pathology ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neovascularization, Pathologic/pathology ; Paget Disease, Extramammary/complications ; Paget Disease, Extramammary/pathology ; Skin Neoplasms/complications ; Skin Neoplasms/pathology ; Sweat Gland Diseases/complications ; Sweat Gland Diseases/pathology
    Language English
    Publishing date 2018-12-01
    Publishing country France
    Document type Case Reports ; Letter
    ZDB-ID 1128666-0
    ISSN 1952-4013 ; 1167-1122
    ISSN (online) 1952-4013
    ISSN 1167-1122
    DOI 10.1684/ejd.2018.3438
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3484: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: How to optimize the sequential use of novel therapeutics in metastatic prostate cancer patients? Response should be found in prostate cancer tissue.

    Francini, Edoardo / Roviello, Giandomenico

    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

    2014  Volume 35, Issue 8, Page(s) 7391–7392

    MeSH term(s) Androstenols/therapeutic use ; Antineoplastic Agents/therapeutic use ; Humans ; Male ; Phenylthiohydantoin/analogs & derivatives ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Taxoids/therapeutic use
    Chemical Substances Androstenols ; Antineoplastic Agents ; Taxoids ; Phenylthiohydantoin (2010-15-3)
    Language English
    Publishing date 2014-05-30
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 605825-5
    ISSN 1423-0380 ; 0289-5447 ; 1010-4283
    ISSN (online) 1423-0380
    ISSN 0289-5447 ; 1010-4283
    DOI 10.1007/s13277-014-2145-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1598: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top