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  1. Article: Doxycycline: From Ocular Rosacea to COVID-19 Anosmia. New Insight Into the Coronavirus Outbreak.

    Bonzano, Chiara / Borroni, Davide / Lancia, Andrea / Bonzano, Elisabetta

    Frontiers in medicine

    2020  Volume 7, Page(s) 200

    Keywords covid19
    Language English
    Publishing date 2020-05-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2020.00200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Doxycycline

    Chiara Bonzano / Davide Borroni / Andrea Lancia / Elisabetta Bonzano

    Frontiers in Medicine, Vol

    From Ocular Rosacea to COVID-19 Anosmia. New Insight Into the Coronavirus Outbreak

    2020  Volume 7

    Keywords COVID-19 ; doxycycline ; coronavirus (CoV) ; SARS – CoV ; anosmia ; Medicine (General) ; R5-920 ; covid19
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Recombinant Human Nerve Growth Factor (Cenegermin)-Driven Corneal Wound Healing Process: An Evidence-Based Analysis.

    Bonzano, Chiara / Olivari, Sara / Cutolo, Carlo Alberto / Macrì, Angelo / Sindaco, Daniele / Borroni, Davide / Bonzano, Elisabetta / Traverso, Carlo Enrico

    Frontiers in pharmacology

    2022  Volume 12, Page(s) 760507

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2022-01-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.760507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Doxycycline

    Bonzano, Chiara / Borroni, Davide / Lancia, Andrea / Bonzano, Elisabetta

    Frontiers in Medicine

    From Ocular Rosacea to COVID-19 Anosmia. New Insight Into the Coronavirus Outbreak

    2020  Volume 7

    Keywords covid19
    Publisher Frontiers Media SA
    Publishing country ch
    Document type Article ; Online
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2020.00200
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Doxycycline

    BONZANO, CHIARA / Borroni, Davide / Lancia, Andrea / BONZANO, ELISABETTA

    From Ocular Rosacea to COVID-19 Anosmia. New Insight Into the Coronavirus Outbreak

    2020  

    Keywords COVID-19 ; doxycycline ; coronavirus (CoV) ; SARS – CoV ; anosmia ; covid19
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Taking care of life: the new Italian law on post-mortem donation for study purposes, training and scientific research.

    Ciliberti, Rosagemma / Bonsignore, Alessandro / Bonzano, Chiara / Ventura, Francesco / Licata, Marta

    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft

    2021  Volume 236, Page(s) 151712

    Abstract: Anatomical dissection is considered a fundamental practice in the medical curriculum. Not only does it help students to familiarize themselves with the various bodily organs and to refine their surgical practice, it also fosters an attitude of awareness ... ...

    Abstract Anatomical dissection is considered a fundamental practice in the medical curriculum. Not only does it help students to familiarize themselves with the various bodily organs and to refine their surgical practice, it also fosters an attitude of awareness and respect towards death and the values of solidarity. On 10th February 2020, the Italian Parliament passed a new law entitled "Rules on the disposition of one's own body and post-mortem tissues for study purposes, training and scientific research". Here, we outline the main ethical and legal aspects of this law and suggest initiatives to encourage body donation. Through careful analysis of the law, we intend to open a discussion on the main ethical issues and to make comparisons with the international situation. The new legislation fills serious gaps in an area of great ethical relevance; not only does it endorse fundamental ethical principles, it also provides important guidelines for strengthening body donation, such as: ensuring respect for the dignity of the deceased, providing express consent, appointing a trustee, promoting information for both doctors and the community, and banning all forms of trade in bodies or body parts. This law is certainly an important milestone on the road to overcoming the scarcity of bodies for study and research. However, it is also essential to promote a favourable attitude to body donation and to strive to overcome obstacles to this practice by supporting continuous dialogue between anatomical institutes and the community. Further studies are necessary in order to assess the impact of the new law.
    MeSH term(s) Autopsy ; Dissection ; Human Body ; Humans ; Italy ; Physicians ; Tissue and Organ Procurement
    Language English
    Publishing date 2021-03-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1106738-x
    ISSN 1618-0402 ; 0940-9602
    ISSN (online) 1618-0402
    ISSN 0940-9602
    DOI 10.1016/j.aanat.2021.151712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Clinical Outcomes of Topical 0.1% Ciclosporin Cationic Emulsion Used on Label in Children with Vernal Keratoconjunctivitis.

    Giannaccare, Giuseppe / Rossi, Costanza / Borselli, Massimiliano / Bonzano, Chiara / Carnovale Scalzo, Giovanna / Nicolò, Massimo / Scorcia, Vincenzo / Traverso, Carlo Enrico / Vagge, Aldo

    Ophthalmology and therapy

    2023  Volume 12, Issue 3, Page(s) 1787–1793

    Abstract: Introduction: The purpose of this short article is to report the clinical outcomes of topical 0.1% ciclosporin cationic emulsion (CsA-CE) used on label in children with vernal keratoconjunctivitis (VKC).: Methods: In this prospective, non-comparative, ...

    Abstract Introduction: The purpose of this short article is to report the clinical outcomes of topical 0.1% ciclosporin cationic emulsion (CsA-CE) used on label in children with vernal keratoconjunctivitis (VKC).
    Methods: In this prospective, non-comparative, observational study children affected by active severe VKC were treated for at least 12 months with topical 0.1% CsA-CE. The drug was instilled in both eyes 4 times daily. Data collected from medical charts for the baseline visit (T0) and 1-year follow-up visit (T1) included symptomatic score (0-15), clinical score (0-15), side effects, rescue therapy (need and total number of courses with 0.1% dexamethasone 4 times daily for 5 days), ocular complications and tolerability (visual analog scale [0-100]).
    Results: Data from 25 children (20 boys, 5 girls; mean [± standard deviation] age 8.40 ± 2.54 years) were included in the study. Of the 25 patients, 23 (92%) used 0.1% CsA-CE eye drops as per label recommendations, including four patients who had prematurely stopped using topical galenic CsA due to side effects. Symptomatic and clinical scores decreased significantly after treatment, with the mean symptomatic score decreasing from 9.76 ± 1.27 at T0 to 3.80 ± 1.08 at T1, and the mean clinical score decreasing from 9.20 ± 1.32 at T0 to 3.44 ± 1.00 at T1; both P < 0.0001). Five patients (20%) required at least one course of rescue medication (mean 3.4 ± 4.8 courses/year). No patients experienced ocular complications during the study, and treatment tolerability was very high (mean score 89.40 ± 5.46).
    Conclusion: Our findings confirm that topical CsA-CE is an effective on-label option for children with VKC in the real-life setting. In our pediatric patient population, CsA-CE provided good clinical outcomes with a limited need for rescue medication, and it was well tolerated by almost all patients, including those who were intolerant to galenic formulations.
    Language English
    Publishing date 2023-04-12
    Publishing country England
    Document type Journal Article
    ISSN 2193-8245
    ISSN 2193-8245
    DOI 10.1007/s40123-023-00707-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Delayed Re-epithelialization After Epithelium-Off Crosslinking: Predictors and Impact on Keratoconus Progression.

    Bonzano, Chiara / Cutolo, Carlo Alberto / Musetti, Donatella / Di Mola, Ilaria / Pizzorno, Chiara / Scotto, Riccardo / Traverso, Carlo Enrico

    Frontiers in medicine

    2021  Volume 8, Page(s) 657993

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2021-10-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.657993
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reoperations for complications within 90 days after gel stent implantation or trabeculectomy.

    Cutolo, Carlo A / Bonzano, Chiara / Catti, Carlo / Pizzorno, Chiara / Bagnis, Alessandro / Traverso, Carlo E / Iester, Michele

    International ophthalmology

    2022  Volume 43, Issue 5, Page(s) 1745–1749

    Abstract: Purpose: To describe reoperations in the operating room for complications that occurred within the first 90 days after gel stent implantation or trabeculectomy at a single institution over 5 years.: Methods: In this retrospective chart review, ... ...

    Abstract Purpose: To describe reoperations in the operating room for complications that occurred within the first 90 days after gel stent implantation or trabeculectomy at a single institution over 5 years.
    Methods: In this retrospective chart review, patients who have undergone gel stent implantation with mitomycin C (MMC) or trabeculectomy with MMC were enrolled. Postoperative complications that required reoperations within the first 90 days were evaluated.
    Results: A total of 510 surgeries were performed on 392 patients over a 57-month period by 2 glaucoma surgeons. Of these, 284 were gel stent implantation, and 226 were trabeculectomy. Combined phacoemulsification was performed in 52/284 (18.3%) in the gel stent group and in 26/226 (11.5%) of eyes in the trabeculectomy group (p = 0.03). Reoperations took place in 13/510 (2.5%) eyes, including 4/284 (1.4%) in the gel stent group, 9/226 (4.0%) in the trabeculectomy group (p = 0.07). In the gel stent group, indications for reoperation were bleb failure (2), suprachoroidal hemorrhage (1), bullous keratopathy (1). In the trabeculectomy group, indications for reoperation were bleb failure (3), overfiltration (2), persistent wound leak (2), aqueous misdirection (2).
    Conclusions: The rates of reoperation for early postoperative complications after gel stent or trabeculectomy was low and comparable with previous studies. A slightly higher number of reoperations within 90 days was observed in the trabeculectomy group than the gel stent group despite the more significant number of combined procedures in the latter group. Bleb failure was the most common indications for reoperation in both groups. Excessive outflow was a cause of reoperation mostly in the trabeculectomy group.
    MeSH term(s) Humans ; Trabeculectomy/adverse effects ; Trabeculectomy/methods ; Retrospective Studies ; Intraocular Pressure ; Reoperation ; Glaucoma/surgery ; Mitomycin ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Treatment Outcome
    Chemical Substances Mitomycin (50SG953SK6)
    Language English
    Publishing date 2022-11-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-022-02575-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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