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  1. Book: Calcium channel blockers: monotherapy and dual therapy considerations in the treatment of hypertension

    Sica, Domenic A.

    (American journal of cardiovascular drugs ; 7, Suppl. 1)

    2007  

    Author's details guest ed. Domenic A. Sica
    Series title American journal of cardiovascular drugs ; 7, Suppl. 1
    Collection
    Language English
    Size 29 S. : graph. Darst.
    Publisher Adis International
    Publishing place Auckland
    Publishing country New Zealand
    Document type Book
    HBZ-ID HT015185530
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Design of a novel controlled release formulation of carvedilol: pharmacology and clinical aspects

    Sica, Domenic A.

    (The American journal of cardiology ; 98,7A = Suppl.)

    2006  

    Title variant Design of a novel controlled-release formulation of carvedilol: pharmacology and clinical aspects
    Author's details guest. ed.: Domenic A. Sica
    Series title The American journal of cardiology ; 98,7A = Suppl.
    Collection
    Language English
    Size 69L S. : graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT014887099
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Conference proceedings: Improvement of clinical outcomes in hypertension: advantages of angiotension receptor blockers

    Sica, Domenic A.

    [Symposium Titled "Improvement of Clinical Outcomes in Hypertension: Advantages of Angiotensin Receptor Blockers", held May 20, 2000, In New York City]

    (American journal of hypertension ; 14,7, Pt. 2 = Suppl.)

    2001  

    Event/congress Symposium Titled Improvement of Clinical Outcomes in Hypertension: Advantages of Angiotensin Receptor Blockers (2000, NewYorkNY)
    Author's details ed. Domenic A. Sica
    Series title American journal of hypertension ; 14,7, Pt. 2 = Suppl.
    Collection
    Language English
    Size S. 225S - 247S : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT013145953
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Vascular disease and the renin angiotensin system in the patient with hypertension

    Sica, Domenic A.

    3 June, 2000, Mystic Seaport, Connecticut, USA

    (Blood pressure monitoring ; 5, Suppl. 2)

    2000  

    Title variant Vascular disease and the renin-angiotensin system in the patient with hypertension
    Series title Blood pressure monitoring ; 5, Suppl. 2
    Collection
    Language English
    Size S29 S. : graph. Darst.
    Publisher Lippincott Williams & Williams
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012861594
    Database Catalogue ZB MED Medicine, Health

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  5. Book ; Online: Hypertension primer

    Izzo, Joseph L. / Sica, Domenic A. / Black, Henry R., 1942-

    the essentials of high blood pressure : basic science, population science, and clinical management

    2008  

    Institution Council for High Blood Pressure Research
    Author's details editors, Joseph L. Izzo Jr., Domenic A. Sica, Henry R. Black
    Keywords Hypertension
    Language English
    Size 1 Online-Ressource
    Edition 4th ed.
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia, PA
    Document type Book ; Online
    Note "From the Council on High Blood Pressure, American Heart Association" ; Includes bibliographical references and index
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-0-7817-8205-0 ; 0-7817-8205-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article ; Online: Mineralocorticoid Receptor Antagonists for Treatment of Hypertension and Heart Failure.

    Sica, Domenic A

    Methodist DeBakey cardiovascular journal

    2015  Volume 11, Issue 4, Page(s) 235–239

    Abstract: Spironolactone and eplerenone are both mineralocorticoid-receptor antagonists. These compounds block both the epithelial and nonepithelial actions of aldosterone, with the latter assuming increasing clinical relevance. Spironolactone and eplerenone both ... ...

    Abstract Spironolactone and eplerenone are both mineralocorticoid-receptor antagonists. These compounds block both the epithelial and nonepithelial actions of aldosterone, with the latter assuming increasing clinical relevance. Spironolactone and eplerenone both affect reductions in blood pressure either as mono- or add-on therapy; moreover, they each afford survival benefits in diverse circumstances of heart failure and the probability of renal protection in proteinuric chronic kidney disease. However, as use of mineralocorticoid-blocking agents has expanded, the hazards inherent in taking such drugs have become more apparent. Whereas the endocrine side effects of spironolactone are in most cases little more than a cosmetic annoyance, the potassium-sparing effects of both spironolactone and eplerenone can prove disastrous, even fatal, if sufficient degrees of hyperkalemia emerge. For most patients, however, the risk of developing hyperkalemia in and of itself should not discourage the sensible clinician from bringing these compounds into play. Hyperkalemia should always be considered a possibility in patients receiving either of these medications; therefore, anticipatory steps should be taken to minimize the likelihood of its occurrence if long-term therapy of these agents is being considered.
    MeSH term(s) Antihypertensive Agents/adverse effects ; Antihypertensive Agents/therapeutic use ; Blood Pressure/drug effects ; Diuretics/adverse effects ; Diuretics/therapeutic use ; Drug Resistance ; Heart Failure/diagnosis ; Heart Failure/drug therapy ; Heart Failure/physiopathology ; Humans ; Hyperkalemia/chemically induced ; Hypertension/diagnosis ; Hypertension/drug therapy ; Hypertension/physiopathology ; Mineralocorticoid Receptor Antagonists/adverse effects ; Mineralocorticoid Receptor Antagonists/therapeutic use ; Risk Factors ; Treatment Outcome
    Chemical Substances Antihypertensive Agents ; Diuretics ; Mineralocorticoid Receptor Antagonists
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2544079-2
    ISSN 1947-6108 ; 1947-6094
    ISSN (online) 1947-6108
    ISSN 1947-6094
    DOI 10.14797/mdcj-11-4-235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Urinary potassium excretion: can it predict the onset of hypertension?

    Sica, Domenic A

    Hypertension (Dallas, Tex. : 1979)

    2014  Volume 64, Issue 4, Page(s) 693–694

    MeSH term(s) Blood Pressure/physiology ; Female ; Humans ; Hypertension/physiopathology ; Hypertension/urine ; Male ; Potassium/urine
    Chemical Substances Potassium (RWP5GA015D)
    Language English
    Publishing date 2014-10
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.114.03874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Aldosterone and volume management in hypertensive heart disease.

    Sica, Domenic A

    Seminars in nephrology

    2014  Volume 34, Issue 3, Page(s) 323–332

    Abstract: Aldosterone-receptor antagonists dose-dependently reduce both the epithelial and nonepithelial actions of aldosterone. These compounds are used commonly in the treatment of hypertension, with or without aldosteronism, and in the volume-overload periods ... ...

    Abstract Aldosterone-receptor antagonists dose-dependently reduce both the epithelial and nonepithelial actions of aldosterone. These compounds are used commonly in the treatment of hypertension, with or without aldosteronism, and in the volume-overload periods of various forms of heart failure, cirrhosis, and renal failure. In this regard, the relevant site of action for these compounds is compartmentalized to the distal nephron. The cardiac benefits of aldosterone-receptor blockade now are sufficiently well established to warrant routine use of these compounds for their survival benefits in moderate to advanced stages of heart failure. Aldosterone-receptor antagonists spironolactone and eplerenone commonly are used in the treatment of resistant forms of hypertension. Spironolactone, but not eplerenone, is a commonly used add-on diuretic that provides incremental benefit for salt-and-water excretion in excess of what may be seen with a loop diuretic given together with a thiazide-type diuretic. The dose-response relationship for natriuresis with spironolactone has not been explored completely as to its combination therapy responses. The quite high doses of spironolactone used in patients with cirrhosis and ascites would infer that the overall treatment effect with this compound exceeds simple receptor blockade and may include a nervous system effect that operationally reduces renal sympathetic nerve traffic. The adverse electrolyte and renal function side effects with aldosterone-receptor antagonists are not uncommon in at-risk patients, such as those with chronic kidney disease, and require that dosing be mindful of the tendency of these drugs to importantly increase serum potassium levels.
    MeSH term(s) Aldosterone ; Area Under Curve ; Diuretics/therapeutic use ; Heart Failure/drug therapy ; Humans ; Hypertension/drug therapy ; Mineralocorticoid Receptor Antagonists/therapeutic use ; Renal Insufficiency, Chronic/drug therapy ; Spironolactone/analogs & derivatives ; Spironolactone/pharmacokinetics ; Spironolactone/therapeutic use
    Chemical Substances Diuretics ; Mineralocorticoid Receptor Antagonists ; Spironolactone (27O7W4T232) ; Aldosterone (4964P6T9RB) ; eplerenone (6995V82D0B)
    Language English
    Publishing date 2014-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2014.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Device-guided breathing and hypertension: a yet to be determined positioning.

    Sica, Domenic A

    Cardiology in review

    2011  Volume 19, Issue 2, Page(s) 45–46

    MeSH term(s) Biofeedback, Psychology/instrumentation ; Blood Pressure ; Equipment and Supplies ; Humans ; Hypertension/prevention & control ; Hypertension/therapy ; Relaxation Therapy/instrumentation ; Relaxation Therapy/methods ; Respiration
    Language English
    Publishing date 2011-03
    Publishing country United States
    Document type Editorial
    ZDB-ID 1294965-6
    ISSN 1538-4683 ; 1061-5377
    ISSN (online) 1538-4683
    ISSN 1061-5377
    DOI 10.1097/CRD.0b013e3181fe2d65
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nondrug interventions for the treatment of hypertension: varying effect.

    Sica, Domenic A

    Journal of clinical hypertension (Greenwich, Conn.)

    2011  Volume 14, Issue 1, Page(s) 3–4

    MeSH term(s) Diet, Sodium-Restricted/methods ; Disease Management ; Health Behavior ; Humans ; Hypertension/psychology ; Hypertension/therapy ; Life Style ; Ubiquinone/analogs & derivatives ; Ubiquinone/therapeutic use ; Vitamins/therapeutic use
    Chemical Substances Vitamins ; Ubiquinone (1339-63-5) ; coenzyme Q10 (EJ27X76M46)
    Language English
    Publishing date 2011-12-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 2077222-1
    ISSN 1751-7176 ; 1524-6175
    ISSN (online) 1751-7176
    ISSN 1524-6175
    DOI 10.1111/j.1751-7176.2011.00572.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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