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  1. Book: Essentials of atrial fibrillation

    Yap, Yee Guan / Camm, Alan John

    2014  

    Author's details Yee Guan Yap ; A. John Camm
    Language English
    Size VIII, 47 S. : Ill., graph. Darst.
    Edition Rev. ed.
    Publisher Springer Healthcare
    Publishing place London
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018528807
    ISBN 978-1-85873-438-5 ; 1-85873-438-X
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Acquired long QT syndrome

    Camm, Alan John / Malik, Marek / Yap, Yee Guan

    2004  

    Author's details A. John Camm ; Marek Malik ; Yee Guan Yap
    Keywords Long QT Syndrome / diagnosis ; Long QT Syndrome / physiopathology ; Pharmaceutical Preparations / adverse effects
    Language English
    Size VI, 199 S. : Ill., graph. Darst.
    Publisher Blackwell u.a.
    Publishing place Malden, Mass
    Publishing country United States
    Document type Book
    HBZ-ID HT013961257
    ISBN 1-4051-1838-5 ; 978-1-4051-1838-5
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Drug induced long QT syndrome

    Yap, Yee Guan / Camm, Alan John

    (Clinical approaches to tachyarrhythmias ; 16)

    2002  

    Title variant Drug-induced long QT syndrome
    Author's details by Yee Guan Yap ; A. John Camm
    Series title Clinical approaches to tachyarrhythmias ; 16
    Collection
    Keywords Long QT Syndrome
    Language English
    Size IX, 110 S. : Ill.,graph. Darst.
    Publisher Futura Publ
    Publishing place Armonk, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT013613918
    ISBN 0-87993-468-9 ; 978-0-87993-468-2
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Inflammation and atrial fibrillation: cause or para-phenomenon?

    Yap, Yee Guan

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2009  Volume 11, Issue 8, Page(s) 980–981

    MeSH term(s) Adipokines ; Atrial Fibrillation/blood ; Atrial Fibrillation/complications ; Atrial Fibrillation/diagnosis ; Biomarkers/blood ; Chitinase-3-Like Protein 1 ; Glycoproteins/blood ; Humans ; Lectins ; Myocarditis/blood ; Myocarditis/complications ; Myocarditis/diagnosis ; Risk Assessment/methods ; Risk Factors
    Chemical Substances Adipokines ; Biomarkers ; CHI3L1 protein, human ; Chitinase-3-Like Protein 1 ; Glycoproteins ; Lectins
    Language English
    Publishing date 2009-08
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/eup191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Essentials of atrial fibrillation

    Yap, Yee Guan / Camm, A. John

    2014  

    Author's details Yee Guan Yap, A. John Camm
    MeSH term(s) Atrial Fibrillation
    Language English
    Size viii, 47 pages :, illustrations
    Edition Revised edition.
    Document type Book
    ISBN 9781858734385 ; 185873438X
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article ; Online: Prolonged QT predicts prognosis in COVID-19.

    Akhtar, Zaki / Gallagher, Mark M / Yap, Yee Guan / Leung, Lisa W M / Elbatran, Ahmed I / Madden, Brendan / Ewasiuk, Victoria / Gregory, Louise / Breathnach, Aodhan / Chen, Zhong / Fluck, David S / Sharma, Sumeet

    Pacing and clinical electrophysiology : PACE

    2021  Volume 44, Issue 5, Page(s) 875–882

    Abstract: Background: Coronavirus disease-2019 (COVID-19) causes severe illness and multi-organ dysfunction. An abnormal electrocardiogram is associated with poor outcome, and QT prolongation during the illness has been linked to pharmacological effects. This ... ...

    Abstract Background: Coronavirus disease-2019 (COVID-19) causes severe illness and multi-organ dysfunction. An abnormal electrocardiogram is associated with poor outcome, and QT prolongation during the illness has been linked to pharmacological effects. This study sought to investigate the effects of the COVID-19 illness on the corrected QT interval (QTc).
    Method: For 293 consecutive patients admitted to our hospital via the emergency department for COVID-19 between 01/03/20 -18/05/20, demographic data, laboratory findings, admission electrocardiograph and clinical observations were compared in those who survived and those who died within 6 weeks. Hospital records were reviewed for prior electrocardiograms for comparison with those recorded on presentation with COVID-19.
    Results: Patients who died were older than survivors (82 vs 69.8 years, p < 0.001), more likely to have cancer (22.3% vs 13.1%, p = 0.034), dementia (25.6% vs 10.7%, p = 0.034) and ischemic heart disease (27.8% vs 10.7%, p < 0.001). Deceased patients exhibited higher levels of C-reactive protein (244.6 mg/L vs 146.5 mg/L, p < 0.01), troponin (1982.4 ng/L vs 413.4 ng/L, p = 0.017), with a significantly longer QTc interval (461.1 ms vs 449.3 ms, p = 0.007). Pre-COVID electrocardiograms were located for 172 patients; the QTc recorded on presentation with COVID-19 was longer than the prior measurement in both groups, but was more prolonged in the deceased group (448.4 ms vs 472.9 ms, pre-COVID vs COVID, p < 0.01). Multivariate Cox-regression analysis revealed age, C-reactive protein and prolonged QTc of >455 ms (males) and >465 ms (females) (p = 0.028, HR 1.49 [1.04-2.13]), as predictors of mortality. QTc prolongation beyond these dichotomy limits was associated with increased mortality risk (p = 0.0027, HR 1.78 [1.2-2.6]).
    Conclusion: QTc prolongation occurs in COVID-19 illness and is associated with poor outcome.
    MeSH term(s) Azithromycin ; COVID-19 ; Electrocardiography ; Female ; Humans ; Hydroxychloroquine ; Long QT Syndrome/diagnosis ; Male ; Prognosis ; SARS-CoV-2
    Chemical Substances Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2021-04-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Essentials of Atrial Fibrillation

    Yap, Yee Guan / Camm, A John

    2014  

    Abstract: Atrial fibrillation (AF) affects an estimated 1-2% of the population and is the most common cause of sustained cardiac arrhythmia. Critically, the number of patients developing AF is expected to double in the next five decades, leading to increased ... ...

    Author's details by Yee Guan Yap, A John Camm
    Abstract Atrial fibrillation (AF) affects an estimated 1-2% of the population and is the most common cause of sustained cardiac arrhythmia. Critically, the number of patients developing AF is expected to double in the next five decades, leading to increased incidence of stroke, heart failure and other serious thromboembolic events. Essentials of Atrial Fibrillation is a timely investigation of current pharmaceutical trends, clinical guidelines, novel treatments, and ongoing pipeline developments, including ground-breaking advances in the use of novel oral anticoagulants

    This handbook offers timely investigation of current pharmaceutical trends, clinical guidelines, novel treatments, and ongoing pipeline developments, including ground-breaking advances in the use of novel oral anticoagulants. ?Atrial fibrillation (AF) affects an estimated 1-2% of the population and is the most common cause of sustained cardiac arrhythmia. Critically, the number of patients developing AF is expected to double in the next five decades, leading to increased incidence of stroke, heart failure and other serious thromboembolic events.
    Keywords Cardiology ; Emergency medicine ; Hematology ; Internal medicine ; Medicine ; Public health ; Medizin / Gesundheit # Allgemeinmedizin ; Medizin / Gesundheit # Innere Medizin ; Medizin / Gesundheit # Sonstiges
    Language English
    Size Online-Ressource (VIII, 47 p. 11 illus., 4 illus. in color), online resource
    Publisher Springer Healthcare Ltd
    Publishing place Tarporley ;s.l
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781858734385 ; 9781907673986 ; 185873438X ; 1907673989
    DOI 10.1007/978-1-907673-98-6
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article ; Online: Molecular sex identification of painted storks (Mycteria leucocephala): using FTA cards, horizontal PAGE and quick silver staining.

    Yee, Elsie Y S / Zainuddin, Zainal Zahari / Ismail, Ahmad / Yap, Chee Kong / Tan, Soon Guan

    Journal of genetics

    2013  Volume 92, Issue 1, Page(s) e15–8

    MeSH term(s) Animals ; Birds/genetics ; Dried Blood Spot Testing ; Electrophoresis, Polyacrylamide Gel ; Genetic Markers ; Microsatellite Repeats ; Molecular Typing ; Sequence Analysis, DNA/methods ; Sex Determination Analysis ; Silver Staining
    Chemical Substances Genetic Markers
    Language English
    Publishing date 2013-03-26
    Publishing country India
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3039-9
    ISSN 0973-7731 ; 0958-8361 ; 0022-1333
    ISSN (online) 0973-7731
    ISSN 0958-8361 ; 0022-1333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Identification of hybrids of painted and milky storks using FTA card-collected blood, molecular markers, and morphologies.

    Yee, Elsie Yoke Sim / Zainuddin, Zainal Zahari / Ismail, Ahmad / Yap, Chee Kong / Tan, Soon Guan

    Biochemical genetics

    2013  Volume 51, Issue 9-10, Page(s) 789–799

    Abstract: Suspicious hybrids of painted storks and milky storks were found in a Malaysian zoo. Blood of these birds was sampled on FTA cards for DNA fingerprinting. Of 44 optimized primers, 6 produced diagnostic markers that could identify hybrids. The markers ... ...

    Abstract Suspicious hybrids of painted storks and milky storks were found in a Malaysian zoo. Blood of these birds was sampled on FTA cards for DNA fingerprinting. Of 44 optimized primers, 6 produced diagnostic markers that could identify hybrids. The markers were based on simple, direct PCR-generated multilocus banding patterns that provided two sets of genetic data, one for each of the two stork species and another for the hybrids. It also revealed that large DNA fragments (3,000 bp) could be amplified from blood collected on FTA cards. When the results of each individual bird's DNA fingerprint were compared with plumage characters, the hybrids were found to express a range of intermediate phenotypic traits of the pure breeds with no dominant plumage characteristic from either parental species.
    MeSH term(s) Animals ; Birds/anatomy & histology ; Birds/classification ; Birds/genetics ; DNA Fingerprinting ; DNA Primers ; Dried Blood Spot Testing ; Genetic Markers ; Hybridization, Genetic ; Microsatellite Repeats ; Phenotype ; Polymerase Chain Reaction
    Chemical Substances DNA Primers ; Genetic Markers
    Language English
    Publishing date 2013-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2168-4
    ISSN 1573-4927 ; 0006-2928
    ISSN (online) 1573-4927
    ISSN 0006-2928
    DOI 10.1007/s10528-013-9607-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of deviation from guideline recommended treatment on breast cancer survival in Asia.

    Ho, Peh Joo / Ow, Samuel Guan Wei / Sim, Yirong / Liu, Jenny / Lim, Swee Ho / Tan, Ern Yu / Tan, Su-Ming / Lee, Soo Chin / Tan, Veronique Kiak-Mien / Yap, Yoon-Sim / Chay, Wen Yee / Tan, Benita Kiat Tee / Wong, Fuh Yong / Li, Jingmei / Hartman, Mikael

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 1330

    Abstract: Breast cancer survival has improved with significant progress in treatment and disease management. However, compliance with treatment varies. Treatment guidelines for older patients are unclear. We aim to identify predictors of noncompliance with ... ...

    Abstract Breast cancer survival has improved with significant progress in treatment and disease management. However, compliance with treatment varies. Treatment guidelines for older patients are unclear. We aim to identify predictors of noncompliance with recommended therapy in a large breast cancer population and assess the impact of noncompliance on survival. Our study included 19,241 non-metastatic female breast cancer patients, of whom 3,158 (16%) died within 10 years post-diagnosis (median survival = 5.8 years). We studied the association between treatment noncompliance and factors with logistic regression, and the impact of treatment noncompliance on survival with a flexible parametric survival model framework. The highest proportion of noncompliance was observed for chemotherapy (18%). Predictors of noncompliance with chemotherapy, radiotherapy and endocrine therapy included age, tumor size, nodal involvement and subtype (except radiotherapy). Factors associated with not receiving surgery included age and subtype. Treatment noncompliance was associated with worse overall survival for surgery (HR: 2.26 [1.80-2.83]), chemotherapy (1.25 [1.11-1.41]), radiotherapy (2.28 [1.94-2.69]) and endocrine therapy (1.70 [1.41-2.04]). Worse survival was similarly observed in older patients for whom guidelines generally do not apply. Our results highlight the importance of following appropriate treatment as recommended by current guidelines. Older patients may benefit from similar recommendations.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Asia/epidemiology ; Breast Neoplasms/epidemiology ; Breast Neoplasms/mortality ; Breast Neoplasms/therapy ; Combined Modality Therapy ; Disease Management ; Female ; Guideline Adherence ; Humans ; Middle Aged ; Practice Guidelines as Topic ; Registries ; Risk Factors
    Language English
    Publishing date 2020-01-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-58007-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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