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  1. Book: Pathogenesis and management of atopic dermatitis

    Shiohara, Tetsuo

    9 tables

    (Current Problems in Dermatology ; 41)

    2011  

    Author's details vol. ed. Tetsuo Shiohara
    Series title Current Problems in Dermatology ; 41
    Current problems in dermatology
    Collection Current problems in dermatology
    Keywords Dermatitis, Atopical ; Endogenes Ekzem
    Subject Essentielles Ekzem ; Essenzielles Ekzem ; Konstitutionelles Ekzem ; Ekzema atopicum ; Atopisches Ekzem ; Dermatitis atopica ; Atopische Dermatitis ; Neurodermitis ; Neurodermitis constitutionalis
    Language English
    Size VII, 169 S. : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT016830622
    ISBN 978-3-8055-9686-2 ; 9783805596879 ; 3-8055-9686-3 ; 3805596871
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 2072 order for loan Magazin

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  2. Article ; Online: Ask Not What AI Can Do to Us, but What We Can Do with AI.

    Shiohara, Tetsuo / Mizukawa, Yoshiko

    The journal of allergy and clinical immunology. In practice

    2022  Volume 10, Issue 1, Page(s) 284–285

    MeSH term(s) Artificial Intelligence ; Humans
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2021.10.046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [SWEATING DISTURBANCE RESULTS IN THE DEVELOPMENT OF ALLERGY].

    Shiohara, Tetsuo

    Arerugi = [Allergy

    2018  Volume 67, Issue 7, Page(s) 923–926

    MeSH term(s) Dermatitis, Atopic ; Humans ; Hypersensitivity ; Sweating
    Language Japanese
    Publishing date 2018-08-23
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    DOI 10.15036/arerugi.67.923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Book ; Conference proceedings: Mini-Symposium: Viral Infection, Allergy and Autoimmunity

    Shiohara, Tetsuo

    [circa 2000]

    (Journal of dermatological science ; 22,3)

    2000  

    Event/congress Mini-Symposium Viral Infection, Allergy and Autoimmunity (2000)
    Author's details section ed.: Tetsuo Shiohara
    Series title Journal of dermatological science ; 22,3
    Collection
    Language English
    Size S. 149 - 212 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT012864105
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 2870 -22- not available for loan Zeitschriften-Lesesaal

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  5. Article ; Online: Protective effects of moisturizers on topical corticosteroid-induced and age-related eccrine sweating impairment in the murine footpad.

    Doi, Takaaki / Ishimaru, Hironobu / Mizukawa, Yoshiko / Shiohara, Tetsuo

    Journal of dermatological science

    2022  Volume 107, Issue 2, Page(s) 105–108

    MeSH term(s) Adrenal Cortex Hormones ; Animals ; Dermatologic Agents/pharmacology ; Emollients/pharmacology ; Mice ; Skin ; Sweating
    Chemical Substances Adrenal Cortex Hormones ; Dermatologic Agents ; Emollients
    Language English
    Publishing date 2022-04-26
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1024446-3
    ISSN 1873-569X ; 0923-1811
    ISSN (online) 1873-569X
    ISSN 0923-1811
    DOI 10.1016/j.jdermsci.2022.04.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Refractory rheumatoid vasculitis complicated by cytomegalovirus reactivation as a manifestation of immune reconstitution inflammatory syndrome.

    Katsuta, Michie / Shiohara, Tetsuo / Asahina, Akihiko

    JAAD case reports

    2020  Volume 6, Issue 7, Page(s) 652–655

    Language English
    Publishing date 2020-05-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2020.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Multiple Fixed Drug Eruption Mimicking Parapsoriasis en Plaque in a Patient with Hepatitis C Virus Infection.

    Katsuta, Michie / Asahina, Akihiko / Shiohara, Tetsuo

    Case reports in dermatology

    2020  Volume 12, Issue 1, Page(s) 25–32

    Abstract: Although hepatitis C virus (HCV) infection is often associated with extrahepatic cutaneous manifestations such as lichen planus, it is unclear whether ... ...

    Abstract Although hepatitis C virus (HCV) infection is often associated with extrahepatic cutaneous manifestations such as lichen planus, it is unclear whether HCV
    Language English
    Publishing date 2020-02-04
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2505300-0
    ISSN 1662-6567
    ISSN 1662-6567
    DOI 10.1159/000505477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): An update in 2019.

    Shiohara, Tetsuo / Mizukawa, Yoshiko

    Allergology international : official journal of the Japanese Society of Allergology

    2019  Volume 68, Issue 3, Page(s) 301–308

    Abstract: The aim of this review was to provide an updated overview of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS). Several new insights have been made, particularly with regards to the diagnosis, ... ...

    Abstract The aim of this review was to provide an updated overview of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS). Several new insights have been made, particularly with regards to the diagnosis, pathogenesis and care of some important complications and sequelae. The indication of herpesvirus reactivations in diagnosis in the assessment of disease severity is now better specified. Nevertheless, because fatal complications and autoimmune sequelae have been under-recognized, there is a clear need to identify effective parameters for assessing disease severity and predicting prognosis of the disease in the early phase. In this regard, we have established a scoring system that can be used to monitor severity, predict prognosis and stratify the risk of developing severe complications including fatal cytomegalovirus (CMV) disease. Regulatory T cells are likely to be central to the mechanism and would represent potential targets for therapeutic approaches that can ameliorate inflammatory responses occurring at the acute phase while preventing the subsequent development of harmful outcomes, such as CMV disease and autoimmune diseases.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Autoimmune Diseases/etiology ; Autoimmune Diseases/prevention & control ; Drug Hypersensitivity Syndrome/complications ; Drug Hypersensitivity Syndrome/diagnosis ; Drug Hypersensitivity Syndrome/drug therapy ; Drug Hypersensitivity Syndrome/pathology ; Herpesviridae/physiology ; Humans ; Prognosis ; Severity of Illness Index ; T-Lymphocytes, Regulatory/physiology ; Virus Activation
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2019-04-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1336498-4
    ISSN 1440-1592 ; 1323-8930
    ISSN (online) 1440-1592
    ISSN 1323-8930
    DOI 10.1016/j.alit.2019.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5248: Show issues Location:
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  9. Article ; Online: Restoration of sweating disturbance in atopic dermatitis treated with dupilumab.

    Mizukawa, Yoshiko / Sato, Yohei / Ohyama, Manabu / Shiohara, Tetsuo

    Journal of dermatological science

    2020  Volume 100, Issue 1, Page(s) 79–81

    MeSH term(s) Adult ; Antibodies, Monoclonal, Humanized/administration & dosage ; Dermatitis, Atopic/complications ; Dermatitis, Atopic/diagnosis ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/immunology ; Female ; Humans ; Hypohidrosis/diagnosis ; Hypohidrosis/drug therapy ; Hypohidrosis/immunology ; Male ; Middle Aged ; Severity of Illness Index ; Sweating/drug effects ; Sweating/immunology ; Treatment Outcome ; Young Adult
    Chemical Substances Antibodies, Monoclonal, Humanized ; dupilumab (420K487FSG)
    Language English
    Publishing date 2020-08-19
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1024446-3
    ISSN 1873-569X ; 0923-1811
    ISSN (online) 1873-569X
    ISSN 0923-1811
    DOI 10.1016/j.jdermsci.2020.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Monocyte-Independent and -Dependent Regulation of Regulatory T-Cell Development in Mycoplasma Infection.

    Takahashi, Ryo / Shiohara, Tetsuo / Mizukawa, Yoshiko

    The Journal of infectious diseases

    2020  Volume 223, Issue 10, Page(s) 1733–1742

    Abstract: Background: Although Mycoplasma pneumoniae (MP) infection has been implicated in the pathogenesis of allergic diseases, the mechanism of this trigger remains unknown. We explored the mechanism for how MP infection could tilt the balance between ... ...

    Abstract Background: Although Mycoplasma pneumoniae (MP) infection has been implicated in the pathogenesis of allergic diseases, the mechanism of this trigger remains unknown. We explored the mechanism for how MP infection could tilt the balance between regulatory T cells (Tregs) and Th17 cells.
    Methods: We analyzed the frequency, phenotype, and function of Tregs in patients at the different stages of MP and various virus infections over a period of more than 1 year. We examined the effect of monocytes to elucidate signals that can regulate the balance between Treg and Th17 cells.
    Results: The functional activity of Tregs was profoundly impaired during the acute stage of MP as well as viral infections. Upon resolution, however, the Treg function remained impaired even 1 year after MP infection. In the resolution stage, the impaired Treg function was associated with an increase in interleukin (IL) 17A+ Tregs and Th17 cells. Development of Th17 cells was dependent on the "aberrant" proinflammatory monocytes (pMOs), characterized by potent ability to produce IL-6 in a Toll-like receptor 2-dependent manner.
    Conclusions: Depending on the prevalence of the pMOs, Tregs and Th17 cells could mutually regulate the number and function of the other. The pMOs/IL-6 could be crucial therapeutic targets against MP-induced allergic diseases.
    MeSH term(s) Humans ; Interleukin-6/immunology ; Monocytes/immunology ; Pneumonia, Mycoplasma/immunology ; T-Lymphocytes, Regulatory/immunology ; Th17 Cells/immunology
    Chemical Substances Interleukin-6
    Language English
    Publishing date 2020-09-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiaa590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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