Article ; Online: SF 6 COMPARED WITH C 2 F 6 FOR INFERIOR RHEGMATOGENOUS RETINAL REPAIR : The Manchester Pseudophakic Retinal Detachment Study.
2024 Volume 44, Issue 5, Page(s) 791–798
Abstract: Purpose: To compare SF 6 relative with C 2 F 6 in the anatomical and functional outcomes following ... vitrectomy repair using SF 6 and C 2 F 6 tamponade between 2011 and 2020 at a tertiary centre ... in the SF 6 and C 2 F 6 groups, respectively ( P = 0.182). Relative to the SF 6 group, the C 2 F 6 group had ...
| Abstract | Purpose: To compare SF 6 relative with C 2 F 6 in the anatomical and functional outcomes following pars plana vitrectomy for uncomplicated primary pseudophakic rhegmatogenous retinal detachment with inferior causative breaks. Methods: This is a retrospective, comparative study on eyes with pseudophakic rhegmatogenous retinal detachment with inferior causative breaks that had small-gauge pars plana vitrectomy repair using SF 6 and C 2 F 6 tamponade between 2011 and 2020 at a tertiary centre in the United Kingdom. Primary outcome was single surgery anatomical success, and the secondary outcome was best-corrected visual acuity. Propensity score matching, using preoperative findings as covariates to account for relevant confounders, was performed. Results: From 162 pseudophakic rhegmatogenous retinal detachment eyes with inferior causative breaks, the median (interquartile range) follow-up was 82 (52-182) days. The single surgery anatomical success was 156 (96.3%) overall: 47 of 47 (100.0%) and 109 of 115 (94.8%) in the SF 6 and C 2 F 6 groups, respectively ( P = 0.182). Relative to the SF 6 group, the C 2 F 6 group had a higher mean number of tears (SF 6 : 3.1[2.0], C 2 F 6 : 4.5[2.7], P = 0.002) and greater retinal detachment extent (SF 6 : 5.3[2.9], C 2 F 6 : 6.2[2.6] clock hours, P = 0.025). Following propensity score matching analysis, 80 eyes were matched with 40 in each group to homogenize preoperative factors. No significant difference was found in single surgery anatomical success and best-corrected visual acuity between the groups following propensity score matching. Conclusion: Primary pars plana vitrectomy with gas tamponade leads to a high single surgery anatomical success rate in uncomplicated pseudophakic rhegmatogenous retinal detachment with inferior causative breaks with no additional benefit associated with long-acting tamponade when comparing C 2 F 6 with SF 6 . |
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| MeSH term(s) | Humans ; Retinal Detachment/surgery ; Retinal Detachment/etiology ; Vitrectomy/methods ; Retrospective Studies ; Female ; Male ; Visual Acuity/physiology ; Pseudophakia/physiopathology ; Pseudophakia/complications ; Endotamponade/methods ; Aged ; Sulfur Hexafluoride/administration & dosage ; Middle Aged ; Fluorocarbons/administration & dosage ; Retinal Perforations/surgery ; Retinal Perforations/etiology ; Retinal Perforations/diagnosis ; Follow-Up Studies ; Treatment Outcome |
| Chemical Substances | Sulfur Hexafluoride (WS7LR3I1D6) ; Fluorocarbons ; perflutren (CK0N3WH0SR) |
| Language | English |
| Publishing date | 2024-01-18 |
| Publishing country | United States |
| Document type | Journal Article ; Comparative Study |
| ZDB-ID | 603192-4 |
| ISSN | 1539-2864 ; 0275-004X |
| ISSN (online) | 1539-2864 |
| ISSN | 0275-004X |
| DOI | 10.1097/IAE.0000000000004051 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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