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Article: Reply: Allocating Medical Resources Efficiently: Importance of Health Literacy during the COVID-19 Pandemic.

Oh, Hong Sang / Lee, Seung Youp / Song, Kyoung-Ho

2022 Volume 54, Issue 2, Page(s) 366

Language	English
Publishing date	2022-05-10
Publishing country	Korea (South)
Document type	Letter
ZDB-ID	2573798-3
ISSN	2093-2340
ISSN	2093-2340
DOI	10.3947/ic.2022.0035
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Article: Impacts of Symptomatic HIV Infection on In-Hospital Cardiopulmonary Resuscitation Outcomes:  A Population-Based Cohort Study in South Korea.

Oh, Tak Kyu / Jo, You Hwan / Song, Kyoung-Ho / Song, In-Ae

Open forum infectious diseases

2022 Volume 9, Issue 5, Page(s) ofac144

Abstract: Background: The impact of HIV infection on survival outcomes after in-hospital cardiopulmonary resuscitation (ICPR) remains controversial. This study aimed to investigate the impacts of HIV infection on both short-term and long-term outcomes after ICPR.! ...

Abstract	Background: The impact of HIV infection on survival outcomes after in-hospital cardiopulmonary resuscitation (ICPR) remains controversial. This study aimed to investigate the impacts of HIV infection on both short-term and long-term outcomes after ICPR. Methods: This nationwide, population-based cohort study used data taken from the South Korean National Health Insurance Service database. All adult (≥18 years old) patients who experienced ICPR between January 1, 2010, and December 31, 2019, were included. Results: A total of 298 676 adult patients who underwent ICPR were initially included in the analysis. Among them, 586 (0.2%) patients were assigned to the patients with symptomatic HIV infection (PWH) group, while 298 090 (99.8%) patients were assigned to the control group. After 1:10 propensity score (PS) matching, 586 patients in the PWH group and 5845 patients in the control group were included in the analysis. Logistic regression analysis after PS matching showed that the PWH group had a 20% lower live discharge rate after ICPR compared with the control group (odds ratio, 0.80; 95% CI, 0.65-0.97; Conclusions: Although the PWH group showed lower live discharge rates compared with the control group after ICPR, long-term survival outcomes from 6 months and 1 year were not significantly different.
Language	English
Publishing date	2022-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofac144
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Article: How Can We Deal with Psychosocial Issues in an Emerging Infectious Disease Outbreak? Lessons from a Qualitative Study for the MERS Outbreak in Korea.

Park, Hye Yoon / Lee, Haewoo / Lee, Ji-Yeon / Song, Kyoung-Ho / Kim, Yeonjae / Lee, So Hee

Infection & chemotherapy

2023 Volume 55, Issue 3, Page(s) 355–367

Abstract: Background: The 2015 Middle East respiratory syndrome (MERS) coronavirus outbreak in Korea led to profound emotional and social burdens, especially in patients and health care professionals.: Materials and methods: Focus group interviews were ... ...

Abstract	Background: The 2015 Middle East respiratory syndrome (MERS) coronavirus outbreak in Korea led to profound emotional and social burdens, especially in patients and health care professionals. Materials and methods: Focus group interviews were conducted with 2 patients, 1 family member and 6 health care professionals about psychological distress related to MERS in 2017 and analyzed the interview data using the consensual qualitative research method. Results: Four domains and 17 core ideas were identified within three interview groups, including psychological distress during the outbreak, problems regarding the response to the outbreak, positive experiences, and future directions for enhancing intervention to improve mental health and prevent psychosocial problems during the outbreak. Psychological consequences were affected by the characteristics of the emerging infectious disease and the structure and process of institutional or governmental response to the MERS outbreak. Mental health services and psychosocial support reduced the negative impact on psychological distress. Conclusion: The MERS outbreak in 2015 gave rise to emotional and social injuries to patients and health care professionals, some of which can be long-lasting constraints in their lives. Preparedness in a society's response to a pandemic considering mental health in related parties can minimize negative psychological consequences and enhance resilience at the individual and society levels.
Language	English
Publishing date	2023-06-07
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2573798-3
ISSN	2093-2340
ISSN	2093-2340
DOI	10.3947/ic.2022.0161
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Article ; Online: False-positive results of galactomannan assays in patients administered glucose-containing solutions.

Shin, Dong Woo / Cho, Jungwon / Choi, Kyung Suk / Lee, Jungwha / Choi, Yunsang / Choi, Seong Jin / Kim, Sang-A / Moon, Song Mi / Kim, Eu Suk / Kim, Hong Bin / Park, Kyoung Un / Hong, Yun Ji / Song, Kyoung-Ho

Scientific reports

2024 Volume 14, Issue 1, Page(s) 2552

Abstract: Galactomannan (GM) is a polysaccharide cell wall component released by Aspergillus spp., and an immunoenzymatic GM assay is used for the diagnosis of invasive pulmonary aspergillosis. We evaluated the cause of strong positivity for GM in patients with no ...

Abstract	Galactomannan (GM) is a polysaccharide cell wall component released by Aspergillus spp., and an immunoenzymatic GM assay is used for the diagnosis of invasive pulmonary aspergillosis. We evaluated the cause of strong positivity for GM in patients with no typical signs of aspergillosis. Repeat assays were performed using different instruments and reagent lots, but there were no differences in results among the assays. Patients with strongly positive GM results were investigated. Medication histories revealed that 14 of 23 patients had been administered total parenteral nutrition solution from one manufacturer and 4 patients had been administered dextrose solution from a different manufacturer before being tested. The results of GM assays conducted on samples of dextrose solution and the glucose fraction of the total parenteral nutrition solution were strongly positive, confirming the causes of the false-positive reactions. We hypothesize that a trace amount of GM was introduced into the glucose-containing solutions because glucoamylase, which is necessary for the saccharification step of glucose synthesis, was derived from Aspergillus niger. To enhance patient care and prevent unnecessary antifungal prescriptions, healthcare providers and manufacturers of healthcare products need to be aware of the possibility of false-positive reactions for GM.
MeSH term(s)	Humans ; Aspergillosis/drug therapy ; Mannans ; Galactose ; Glucose/therapeutic use ; Parenteral Nutrition Solutions ; Sensitivity and Specificity ; Antigens, Fungal
Chemical Substances	galactomannan (11078-30-1) ; Mannans ; Galactose (X2RN3Q8DNE) ; Glucose (IY9XDZ35W2) ; Parenteral Nutrition Solutions ; Antigens, Fungal
Language	English
Publishing date	2024-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53116-x
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Article ; Online: Staphylococcus argenteus

Lee, Minkyeong / Choi, Yunsang / Choi, Seong Jin / Moon, Song Mi / Kim, Eu Suk / Kim, Hong Bin / Ahn, Soyeon / Lee, Hyunju / Kim, Jaeeun / Shin, Dong Woo / Yeom, Jinki / Park, Jeong Su / Song, Kyoung-Ho

Microbiology spectrum

2024 Volume 12, Issue 2, Page(s) e0279823

Abstract: In 2015, ...

Abstract	In 2015,
MeSH term(s)	Humans ; Staphylococcus aureus ; Staphylococcal Infections/microbiology ; Republic of Korea ; Bacteremia/microbiology ; Staphylococcus
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2807133-5
ISSN	2165-0497 ; 2165-0497
ISSN (online)	2165-0497
ISSN	2165-0497
DOI	10.1128/spectrum.02798-23
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Article: Comparison of All-Cause Mortality Between Individuals With COVID-19 and Propensity Score-Matched Individuals Without COVID-19 in South Korea.

Oh, Tak Kyu / Song, In-Ae / Song, Kyoung-Ho / Jeon, Young-Tae

Open forum infectious diseases

2021 Volume 8, Issue 4, Page(s) ofab057

Abstract: Background: We compared all-cause mortality between individuals in South Korea with and without coronavirus disease 2019 (COVID-19) using propensity score (PS) matching.: Methods: This population-based cohort study used data from the National Health ... ...

Abstract	Background: We compared all-cause mortality between individuals in South Korea with and without coronavirus disease 2019 (COVID-19) using propensity score (PS) matching. Methods: This population-based cohort study used data from the National Health Insurance Service COVID-19 cohort database. In the database, we included individuals (COVID-19 patients, control population, and test-negative individuals) aged 20 years or older, regardless of hospitalization. The primary end point was all-cause mortality between January 1, 2020, and August 27, 2020. Results: A total of 328 374 adults were included in the study: 7713 and 320 660 in the COVID-19 group and the control group. After PS matching, a total of 15 426 individuals (7713 per group) were included in the analysis. All-cause mortality was 3.2% (248/7713) and 1.6% (126/7713) in the COVID-19 group and the control group, respectively. In Cox regression analysis after PS matching, the risk of death in the COVID-19 group was twice as high (hazard ratio, 2.00; 95% CI, 1.61-2.48; Conclusions: In South Korea, all-cause mortality was twice as high among individuals with COVID-19 as among those with similar underlying risks, primarily because of the elevated COVID-19-associated mortality in those aged ≥60 years. Our results highlight the need for prevention of COVID-19 with respect to mortality as a public health outcome.
Language	English
Publishing date	2021-02-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofab057
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Article ; Online: Case Report and Literature Review of Occupational Transmission of Monkeypox Virus to Healthcare Workers, South Korea.

Choi, Yunsang / Jeon, Eun-Bi / Kim, Taeyoung / Choi, Seong Jin / Moon, Song Mi / Song, Kyoung-Ho / Kim, Hong Bin / Kim, Eu Suk

Emerging infectious diseases

2023 Volume 29, Issue 5, Page(s) 997–1001

Abstract: We report a case of occupational monkeypox virus infection from a needlestick injury in a healthcare worker in South Korea and review similar reports in the literature during 2022. Postexposure prophylactic treatment with a third-generation smallpox ... ...

Abstract	We report a case of occupational monkeypox virus infection from a needlestick injury in a healthcare worker in South Korea and review similar reports in the literature during 2022. Postexposure prophylactic treatment with a third-generation smallpox vaccine and antiviral agent tecovirimat inhibited local virus spread and alleviated lesion pain.
MeSH term(s)	Humans ; Monkeypox virus ; Smallpox Vaccine ; Needlestick Injuries ; Health Personnel ; Republic of Korea/epidemiology ; Mpox (monkeypox)/diagnosis ; Mpox (monkeypox)/epidemiology
Chemical Substances	Smallpox Vaccine
Language	English
Publishing date	2023-03-01
Publishing country	United States
Document type	Review ; Case Reports ; Journal Article
ZDB-ID	1380686-5
ISSN	1080-6059 ; 1080-6040
ISSN (online)	1080-6059
ISSN	1080-6040
DOI	10.3201/eid2905.230028
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Article ; Online: In-vitro

Park, Jeong Su / Choi, Yun Jung / Kwon, Kyungmi / Choi, Seong Jin / Moon, Song Mi / Song, Kyoung-Ho / Kim, Eu Suk / Park, Kyoung Un / Kim, Hong Bin

Annals of laboratory medicine

2023 Volume 43, Issue 4, Page(s) 389–391

MeSH term(s)	Humans ; Methicillin-Resistant Staphylococcus aureus ; Oxazolidinones/pharmacology ; Anti-Bacterial Agents/pharmacology ; Sepsis ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/drug therapy ; Microbial Sensitivity Tests ; Cross Infection
Chemical Substances	delpazolid (43EP6XV33E) ; Oxazolidinones ; Anti-Bacterial Agents
Language	English
Publishing date	2023-02-24
Publishing country	Korea (South)
Document type	Letter
ZDB-ID	2677441-0
ISSN	2234-3814 ; 2234-3814
ISSN (online)	2234-3814
ISSN	2234-3814
DOI	10.3343/alm.2023.43.4.389
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Article: Association of Repeated Blood Cultures With Mortality in Adult Patients With Gram-Negative Bacilli Bacteremia: A Systematic Review and Meta-analysis.

Shinohara, Jun / Hanai, Shogo / Jung, Jongtak / Song, Kyoung-Ho / Iwata, Mitsunaga / Terasawa, Teruhiko

Open forum infectious diseases

2022 Volume 9, Issue 12, Page(s) ofac568

Abstract: Background: Performing repeat blood cultures after an initial positive culture (ie, follow-up blood cultures [FUBCs]) in patients with gram-negative bacilli (GNB) bacteremia is controversial. We aimed to comprehensively review the association of FUBCs ... ...

Abstract	Background: Performing repeat blood cultures after an initial positive culture (ie, follow-up blood cultures [FUBCs]) in patients with gram-negative bacilli (GNB) bacteremia is controversial. We aimed to comprehensively review the association of FUBCs with improvement in patient-relevant clinical outcomes in GNB bacteremia. Methods: We performed a systematic review and random-effects meta-analysis to calculate summary effect estimates. We used hazard ratios as the effect measure. The primary outcome was 30-day or in-hospital mortality, and secondary outcomes were length of treatment and length of hospital stay. We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials (Central) without language restrictions from inception to April 29, 2022. Original clinical studies evaluating the association between FUBCs and mortality in adult patients with GNB bacteremia were included. FUBC details were reviewed. Two independent reviewers used the Risk of Bias in Non-randomised Studies of Interventions tool. Results: We identified 9 eligible retrospective studies. In total, 7778 hospitalized patients with GNB bacteremia were included. The studies were clinically heterogeneous and had a critical risk of bias. The utilization of FUBCs varied across studies (18%-89%). Random-effects meta-analysis of covariate-adjusted estimates found that FUBC use was associated with reduced mortality. Although not a result of the meta-analysis, lengths of treatment and hospital stay were longer for patients with FUBCs than for those without. Adverse events were not reported. Conclusions: FUBC acquisition was associated with lower mortality and longer hospital stay and treatment duration in GNB bacteremia. The risk of bias was critical, and no firm data were available to support mechanisms.
Language	English
Publishing date	2022-11-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2757767-3
ISSN	2328-8957
ISSN	2328-8957
DOI	10.1093/ofid/ofac568
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Article ; Online: Development of diagnostic tests for pathogen identification and detection of antimicrobial resistance on WHO global priority pathogens using modular real-time nucleic acid amplification test.

Bang, Eunsik / Oh, Sujin / Cho, Hee Won / Park, Da-Ha / Chang, Ho Eun / Park, Jeong Su / Lee, Hyunju / Song, Kyoung-Ho / Kim, Eu Suk / Kim, Hong Bin / Suh, Young Ho / Park, Kyoung Un

International microbiology : the official journal of the Spanish Society for Microbiology

2023 Volume 26, Issue 3, Page(s) 563–577

Abstract: Background: Concerns regarding antimicrobial resistance (AMR) have resulted in the World Health Organization (WHO) designating so-called global priority pathogens (GPPs). However, little discussion has focused on the diagnosis of GPPs. To enable the ... ...

Abstract	Background: Concerns regarding antimicrobial resistance (AMR) have resulted in the World Health Organization (WHO) designating so-called global priority pathogens (GPPs). However, little discussion has focused on the diagnosis of GPPs. To enable the simultaneous identification of pathogens and AMR, we developed a modular real-time nucleic acid amplification test (MRT-NAAT). Methods: Sequence-specific primers for each modular unit for MRT-NAAT pathogen identification and AMR sets were designed. The composition of the reaction mixture and the real-time PCR program were unified irrespective of primer type so to give MRT-NAAT modularity. Standard strains and clinical isolates were used to evaluate the performance of MRT-NAAT by real-time PCR and melting curve analysis. Probit analysis for the MRT-NAAT pathogen identification set was used to assess the limit of detection (LoD). Results: The MRT-NAAT pathogen identification set was made up of 15 modular units 109-199 bp in product size and with a T Conclusions: MRT-NAAT enables pathogen identification and AMR gene detection and is time-effective. By unifying the reaction settings of each modular unit, the modularity where combinations of primers can be used according to need could be achieved. This would greatly help in reflecting the researcher's need and the AMR status of a certain region while successfully detecting pathogens and AMR genes.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial/genetics ; Nucleic Acid Amplification Techniques/methods ; World Health Organization ; Diagnostic Tests, Routine
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2023-01-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1454951-7
ISSN	1618-1905 ; 1139-6709
ISSN (online)	1618-1905
ISSN	1139-6709
DOI	10.1007/s10123-023-00321-9
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