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  1. Article ; Online: Dreaming outside the Box: Evidence for Memory Abstraction in REM Sleep.

    Konkoly, Karen R / Picard-Deland, Claudia / Morris, Daniel / Mallett, Remington

    The Journal of neuroscience : the official journal of the Society for Neuroscience

    2023  Volume 43, Issue 42, Page(s) 6952–6953

    MeSH term(s) Sleep, REM ; Dreams ; Wakefulness ; Cues
    Language English
    Publishing date 2023-10-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Comment
    ZDB-ID 604637-x
    ISSN 1529-2401 ; 0270-6474
    ISSN (online) 1529-2401
    ISSN 0270-6474
    DOI 10.1523/JNEUROSCI.1374-23.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Special issue: Pediatric pain and sickle cell disease.

    Brown, Melanie / Anheyer, Dennis / Morris, Claudia R

    Complementary therapies in medicine

    2022  Volume 71, Page(s) 102880

    Language English
    Publishing date 2022-08-26
    Publishing country Scotland
    Document type Editorial
    ZDB-ID 1155895-7
    ISSN 1873-6963 ; 0965-2299
    ISSN (online) 1873-6963
    ISSN 0965-2299
    DOI 10.1016/j.ctim.2022.102880
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  3. Article ; Online: Reply to Letter to the Editor regarding hospital-based triage travel screens during the COVID-19 pandemic.

    Morris, Claudia R / Iyer, Srikant

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2021  Volume 107, Page(s) 165

    MeSH term(s) COVID-19 ; Child ; Health Personnel ; Hospitals ; Humans ; Pandemics ; Prevalence ; SARS-CoV-2 ; Triage
    Language English
    Publishing date 2021-04-13
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2021.04.016
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  4. Article ; Online: Arginine Therapy Shows Promise for Treatment of Sickle Cell Disease Clinical Subphenotypes of Hemolysis and Arginine Deficiency.

    Morris, Claudia R

    Anesthesia and analgesia

    2017  Volume 124, Issue 4, Page(s) 1369–1370

    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000001874
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  5. Article ; Online: Low global arginine bioavailability: a common phenomenon in pulmonary hypertension.

    Hatabah, Dunia / De Marco, Teresa / McGlothlin, Dana P / Malloy, Mary / Reyes, Loretta Z / Korman, Rawan / Kato, Gregory J / Morris, Claudia R

    American journal of physiology. Lung cellular and molecular physiology

    2024  Volume 326, Issue 4, Page(s) L514–L515

    MeSH term(s) Humans ; Hypertension, Pulmonary ; Arginine/pharmacokinetics ; Biological Availability
    Chemical Substances Arginine (94ZLA3W45F)
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Letter
    ZDB-ID 1013184-x
    ISSN 1522-1504 ; 1040-0605
    ISSN (online) 1522-1504
    ISSN 1040-0605
    DOI 10.1152/ajplung.00026.2024
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  6. Article ; Online: Impact of Arginine Therapy on Kyotorphin in Children with Sickle Cell Disease and Vasoocclusive Pain.

    Korman, Rawan / Hatabah, Dunia / Brown, Lou Ann / Harris, Frank / Wilkinson, Hagar / Rees, Chris A / Bakshi, Nitya / Archer, David R / Dampier, Carlton D / Morris, Claudia R

    Blood advances

    2024  

    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2915908-8
    ISSN 2473-9537 ; 2473-9529
    ISSN (online) 2473-9537
    ISSN 2473-9529
    DOI 10.1182/bloodadvances.2023012209
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  7. Article ; Online: Arginine Therapy and Cardiopulmonary Hemodynamics in Hospitalized Children with Sickle Cell Anemia: A Prospective, Double-blinded, Randomized Placebo-controlled Clinical Trial.

    Onalo, Richard / Cilliers, Antoinette / Cooper, Peter / Morris, Claudia R

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 1, Page(s) 70–80

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Acute Chest Syndrome ; Adolescent ; Anemia, Sickle Cell/complications ; Anemia, Sickle Cell/drug therapy ; Arginine/therapeutic use ; Child ; Child, Hospitalized ; Child, Preschool ; Hemodynamics ; Humans ; Nitric Oxide/therapeutic use ; Pain/drug therapy ; Prospective Studies
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 2022-04-11
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202108-1930OC
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  8. Article ; Online: A More Balanced Approach to Dietary Supplement Data.

    Sibinga, Erica M S / Morris, Claudia R

    JAMA pediatrics

    2019  Volume 173, Issue 1, Page(s) 104

    MeSH term(s) Adolescent ; Child ; Dietary Supplements ; Humans ; Prevalence
    Language English
    Publishing date 2019-01-11
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701223-2
    ISSN 2168-6211 ; 2168-6203
    ISSN (online) 2168-6211
    ISSN 2168-6203
    DOI 10.1001/jamapediatrics.2018.4029
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  9. Article ; Online: Alterations of the arginine metabolome in sickle cell disease: a growing rationale for arginine therapy.

    Morris, Claudia R

    Hematology/oncology clinics of North America

    2014  Volume 28, Issue 2, Page(s) 301–321

    Abstract: Low global arginine bioavailability (GAB) is associated with numerous complications of SCD including early mortality. Mechanisms of arginine dysregulation involve a complex paradigm of excess activity of the arginine-consuming enzyme arginase, elevated ... ...

    Abstract Low global arginine bioavailability (GAB) is associated with numerous complications of SCD including early mortality. Mechanisms of arginine dysregulation involve a complex paradigm of excess activity of the arginine-consuming enzyme arginase, elevated levels of asymmetric dimethylarginine, altered intracellular arginine transport, and nitric oxide synthase dysfunction. Restoration of GAB through exogenous supplementation is therefore, a promising therapeutic target. Studies of arginine therapy demonstrate efficacy in treating patients with leg ulcers, pulmonary hypertension risk, and pain. Co-administration with hydroxyurea increases levels of nitrite and fetal hemoglobin. Addressing the alterations in the arginine metabolome may result in new strategies for treatment of SCD.
    MeSH term(s) Anemia, Sickle Cell/drug therapy ; Anemia, Sickle Cell/metabolism ; Antisickling Agents/therapeutic use ; Arginine/metabolism ; Arginine/therapeutic use ; Drug Therapy, Combination ; Fetal Hemoglobin/metabolism ; Humans ; Hydroxyurea/therapeutic use ; Metabolome ; Treatment Outcome
    Chemical Substances Antisickling Agents ; Fetal Hemoglobin (9034-63-3) ; Arginine (94ZLA3W45F) ; Hydroxyurea (X6Q56QN5QC)
    Language English
    Publishing date 2014-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2013.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Incidence of SARS-CoV-2 Seropositivity in Pediatric Healthcare Workers Prior to Widespread Vaccination: A Five-month Longitudinal Cohort Study.

    Griffiths, Mark / Hatabah, Dunia / Sullivan, Patrick / Mantus, Grace / Sanchez, Travis / Zlotorzynska, Maria / Heilman, Stacy / Camacho-Gonzalez, Andres / Leake, Deborah / Korman, Rawan / Le, Mimi / Suthara, Mehul / Wrammert, Jens / Vos, Miriam B / Morris, Claudia R

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2024  , Page(s) 107064

    Abstract: ... Neutralization antibodies correlated to SARs-CoV-2 binding antibodies (r=0.43,p<0.0001).: Conclusion: Incidence ...

    Abstract Objectives: Determine SARS-CoV-2 IgG antibody incidence over time in unvaccinated pediatric healthcare workers (pHCWs).
    Design: Prospective longitudinal cohort of unvaccinated pHCWs measuring incidence of new infection after initial prevalence was established at 4.1% with seropositive predominance in emergency department (ED)-based pHCWs. Serum samples were collected at follow-up visits to detect new SARS-CoV-2 seropositivity. Univariate analysis was performed to estimate different incidence rates between participant demographics, job, employment location and community risk factors. Anxiety levels about COVID-19 were collected. SARS-CoV-2 antibody decay post-infection, and neutralization antibodies were evaluated. Log-linear Poisson regression models were used to estimate incidence.
    Results: Of 642 initially enrolled, 390 pHCWs presented for at least one follow-up serology test after baseline analysis. Incidence of SARS-CoV-2 seropositivity was 8.2%. The seropositive cohort, like the negative one consisted mainly of females in non-ED settings and non-physician roles. There were no statistically significant differences in incidence across variables. Seropositive participants dropped antibody titers by 50% at 3 months. Neutralization antibodies correlated to SARs-CoV-2 binding antibodies (r=0.43,p<0.0001).
    Conclusion: Incidence of seropositivity was 8.2%. Although seropositivity was higher among ED staff during early stages of the pandemic, this difference declined over time, likely due to universal adoption of personal protective equipment (PPE).
    Language English
    Publishing date 2024-04-17
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2024.107064
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