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Article ; Online: What is the 'normal life expectancy' with ascending aorta disease?

Krüger, Tobias / Salewski, Christoph / Sandoval Boburg, Rodrigo / Schlensak, Christian

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2022 Volume 62, Issue 3

MeSH term(s)	Aorta/surgery ; Aortic Aneurysm/surgery ; Cohort Studies ; Humans ; Life Expectancy
Language	English
Publishing date	2022-09-16
Publishing country	Germany
Document type	Editorial ; Comment
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezac244
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Article ; Online: Needle penetration test - qualifying examination of 3D printable silicones for vascular models in surgical practice.

von Steuben, Thore / Salewski, Christoph / Xepapadeas, Alexander B / Mutschler, Moritz / Spintzyk, Sebastian

3D printing in medicine

2021 Volume 7, Issue 1, Page(s) 21

Abstract: Background: During cardiogenic shock blood circulation is minimal in the human body and does not suffice to survive. The extracorporeal life support system (ECLS) acts as a miniature heart-lung-machine that can be temporarily implanted over major ... ...

Abstract	Background: During cardiogenic shock blood circulation is minimal in the human body and does not suffice to survive. The extracorporeal life support system (ECLS) acts as a miniature heart-lung-machine that can be temporarily implanted over major vessels e.g. at the groin of the patient to bridge cardiogenic shock. To perform this procedure in an emergency, a proper training model is desirable. Therefore, a 3-dimensional-printable (3D) material must be found that mimics large vessel needle penetration properties. A suitable test bench for material comparison is desirable. Methods: A test setup was built, which simulated the clinically relevant wall tension in specimens. The principle was derived from an existing standardized needle penetration test. After design, the setup was fabricated by means of 3D printing and mounted onto an universal testing machine. For testing the setup, a 3D printable polymer with low Shore A hardness and porcine aorta were used. The evaluation was made by comparing the curves of the penetration force to the standardized test considering the expected differences. Results: 3D printing proved to be suitable for manufacturing the test setup, which finally was able to mimic wall tension as if under blood pressure and penetration angle. The force displacement diagrams showed the expected curves and allowed a conclusion to the mechanical properties of the materials. Although the materials forces deviated between the porcine aorta and the Agilus30 polymer, the graphs showed similar but still characteristic curves. Conclusions: The test bench provided the expected results and was able to show the differences between the two materials. To improve the setup, limitations has been discussed and changes can be implemented without complications.
Language	English
Publishing date	2021-08-13
Publishing country	England
Document type	Journal Article
ISSN	2365-6271
ISSN (online)	2365-6271
DOI	10.1186/s41205-021-00110-y
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Article: Influence of Obesity on Short-Term Surgical Outcomes in HFrEF Patients Undergoing CABG: A Retrospective Multicenter Study.

Biomedicines

2024 Volume 12, Issue 2

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2024-02-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines12020426
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Article ; Online: Mitral Valve Surgery via Upper Ministernotomy: Single-Centre Experience in More than 400 Patients.

Radwan, Medhat / Salewski, Christoph / Hecker, Florian / Miskovic, Aleksandra / Risteski, Petar / Hlavicka, Jan / Moritz, Anton / Walther, Thomas / Holubec, Tomas

Medicina (Kaunas, Lithuania)

2021 Volume 57, Issue 11

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Cardiac Surgical Procedures ; Female ; Humans ; Male ; Middle Aged ; Mitral Valve/surgery ; Mitral Valve Insufficiency ; Reoperation ; Retrospective Studies ; Sternotomy ; Treatment Outcome
Language	English
Publishing date	2021-10-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina57111179
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Article ; Online: Needle penetration test - qualifying examination of 3D printable silicones for vascular models in surgical practice

Thore von Steuben / Christoph Salewski / Alexander B. Xepapadeas / Moritz Mutschler / Sebastian Spintzyk

3D Printing in Medicine, Vol 7, Iss 1, Pp 1-

2021 Volume 9

Abstract: Abstract Background During cardiogenic shock blood circulation is minimal in the human body and does not suffice to survive. The extracorporeal life support system (ECLS) acts as a miniature heart-lung-machine that can be temporarily implanted over major ...

Abstract	Abstract Background During cardiogenic shock blood circulation is minimal in the human body and does not suffice to survive. The extracorporeal life support system (ECLS) acts as a miniature heart-lung-machine that can be temporarily implanted over major vessels e.g. at the groin of the patient to bridge cardiogenic shock. To perform this procedure in an emergency, a proper training model is desirable. Therefore, a 3-dimensional-printable (3D) material must be found that mimics large vessel needle penetration properties. A suitable test bench for material comparison is desirable. Methods A test setup was built, which simulated the clinically relevant wall tension in specimens. The principle was derived from an existing standardized needle penetration test. After design, the setup was fabricated by means of 3D printing and mounted onto an universal testing machine. For testing the setup, a 3D printable polymer with low Shore A hardness and porcine aorta were used. The evaluation was made by comparing the curves of the penetration force to the standardized test considering the expected differences. Results 3D printing proved to be suitable for manufacturing the test setup, which finally was able to mimic wall tension as if under blood pressure and penetration angle. The force displacement diagrams showed the expected curves and allowed a conclusion to the mechanical properties of the materials. Although the materials forces deviated between the porcine aorta and the Agilus30 polymer, the graphs showed similar but still characteristic curves. Conclusions The test bench provided the expected results and was able to show the differences between the two materials. To improve the setup, limitations has been discussed and changes can be implemented without complications.
Keywords	Material testing ; Needle penetration test ; Rapid prototyping ; Additive manufacturing ; 3D printable silicones ; DIY lab-equipment ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	670
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The impact of 3D printed models on spatial orientation in echocardiography teaching.

Salewski, Christoph / Nemeth, Attila / Sandoval Boburg, Rodrigo / Berger, Rafal / Hamdoun, Hasan / Frenz, Hannes / Spintzyk, Sebastian / Hahn, Julia Kelley / Schlensak, Christian / Krüger, Tobias

BMC medical education

2022 Volume 22, Issue 1, Page(s) 180

Abstract: Purpose: During our transthoracic echocardiography (TTE) courses, medical students showed difficulty in spatial orientation. We implemented the use of 3D printed cardiac models of standard TTE views PLAX, PSAX, and A4C and assessed their efficacy in TTE- ...

Abstract	Purpose: During our transthoracic echocardiography (TTE) courses, medical students showed difficulty in spatial orientation. We implemented the use of 3D printed cardiac models of standard TTE views PLAX, PSAX, and A4C and assessed their efficacy in TTE-teaching. Methods: One hundred fifty-three participants were split into two groups. A pre-test-retest of anatomy, 2D -, and 3D orientation was conducted. The intervention group (n = 77) was taught using 3D models; the control group (n = 76) without. Both were comparable with respect to baseline parameters. Besides test-scores, a Likert scale recorded experiences, difficulties, and evaluation of teaching instruments. Results: From the 153 students evaluated, 123 improved, 20 did worse, and ten achieved the same result after the course. The median overall pre-test score was 29 of 41 points, and the retest score was 35 (p < 0.001). However, the intervention group taught with the 3D models, scored significantly better overall (p = 0.016), and in 2D-thinking (p = 0.002) and visual thinking (p = 0.006) subtests. A backward multivariate linear regression model revealed that the 3D models are a strong individual predictor of an excellent visual thinking score. In addition, our study showed that students with difficulty in visual thinking benefited considerably from the 3D models. Conclusion: Students taught using the 3D models significantly improved when compared with conventional teaching. Students regarded the provided models as most helpful in their learning process. We advocate the implementation of 3D-printed heart models featuring the standard views for teaching echocardiography. These findings may be transferable to other evidence based medical and surgical teaching interventions.
MeSH term(s)	Echocardiography ; Humans ; Models, Anatomic ; Orientation, Spatial ; Printing, Three-Dimensional ; Students, Medical
Language	English
Publishing date	2022-03-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2044473-4
ISSN	1472-6920 ; 1472-6920
ISSN (online)	1472-6920
ISSN	1472-6920
DOI	10.1186/s12909-022-03242-9
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Article ; Online: Video assisted thoracoscopic sympathectomy for intractable recurrent VT after minimal-invasive LVAD implantation.

Salewski, Christoph / Nemeth, Attila / Sandoval Boburg, Rodrigo / Steger, Volker / Krüger, Tobias / Schreieck, Jürgen / Schlensak, Christian / Popov, Aron-Frederik

Journal of cardiac surgery

2020 Volume 35, Issue 7, Page(s) 1708–1710

Abstract: Background: Recurrent ventricular tachycardia (VT) can occur after left ventricular assist device (LVAD) implantation. In this case, medical treatment might be insufficient. We report a case of a left-sided thoracoscopic sympathectomy as a feasible ... ...

Abstract	Background: Recurrent ventricular tachycardia (VT) can occur after left ventricular assist device (LVAD) implantation. In this case, medical treatment might be insufficient. We report a case of a left-sided thoracoscopic sympathectomy as a feasible treatment escalation in intractable VT. Case report: A 72-year-old patient underwent an internal cardioverter defibrillator (ICD) implantation as primary prophylaxis for VTs in the setting of staged heart failure therapy. Afterwards, due to a progressive dilative cardiomyopathy he underwent a minimal-invasive LVAD implantation (HeartWare, Medtronic). After an uneventful minimal-invasive LVAD-implantation the patient was discharged to a rehabilitation program. However, after 7 weeks he developed recurrent VTs which were successfully terminated by ICD shocks deliveries leading to severe discomfort and frequent hospitalizations. Eventually, the patient was admitted with an electrical VT storm. Successful endocardial catheter ablation of all inducible VTs were performed combined with multiple rearrangements of his oral antiarrhythmic medication. However, all these treatments could not suppress further occurrence of VTs. After an interdisciplinary discussion the patient agreed to a left-sided video-assisted thoracoscopic sympathectomy. After a follow up of 150 days the patient was free from VTs apart from one short event. Conclusion: We believe video-assisted thoracoscopic sympathectomy might be a surgical treatment option in patients with intractable recurrent VTs after catheter ablation of VT reentrant substrate even after minimal-invasive LVAD implantation.
MeSH term(s)	Aged ; Heart Failure/etiology ; Heart Failure/surgery ; Heart Ventricles/surgery ; Heart-Assist Devices/adverse effects ; Humans ; Male ; Minimally Invasive Surgical Procedures/adverse effects ; Minimally Invasive Surgical Procedures/methods ; Mitral Valve Insufficiency/complications ; Prosthesis Implantation/adverse effects ; Recurrence ; Sympathectomy/methods ; Tachycardia, Ventricular/etiology ; Tachycardia, Ventricular/surgery ; Thoracic Surgery, Video-Assisted/methods ; Treatment Outcome
Language	English
Publishing date	2020-05-21
Publishing country	United States
Document type	Case Reports
ZDB-ID	639059-6
ISSN	1540-8191 ; 0886-0440
ISSN (online)	1540-8191
ISSN	0886-0440
DOI	10.1111/jocs.14639
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Article ; Online: Mitral Valve Surgery via Upper Ministernotomy

Medhat Radwan / Christoph Salewski / Florian Hecker / Aleksandra Miskovic / Petar Risteski / Jan Hlavicka / Anton Moritz / Thomas Walther / Tomas Holubec

Medicina, Vol 57, Iss 1179, p

Single-Centre Experience in More than 400 Patients

2021 Volume 1179

Abstract: Background: Minimally invasive mitral valve (MV) surgery has emerged as an alternative to conventional sternotomy aiming to decrease surgical trauma. The aim of the study was to describe our experience with minimally invasive MV surgery through partial ... ...

Abstract	Background: Minimally invasive mitral valve (MV) surgery has emerged as an alternative to conventional sternotomy aiming to decrease surgical trauma. The aim of the study was to describe our experience with minimally invasive MV surgery through partial upper sternotomy (PUS) regarding short- and long-term outcomes. Methods: From January 2004 through March 2014, 419 patients with a median age of 58.9 years (interquartile range 18.7; 31.7% females) underwent isolated primary MV surgery using PUS. Myxomatous degenerative MV disease was the predominant pathology (77%). The patients’ mean EuroSCORE II risk profile was 3.9 ± 3.6%. Results: Mitral valve repair was performed in 384 patients (91.6%) and replacement in 35 patients (8.4%). Thirty-day mortality was 3.1%. In total, 29 (6.9%) deaths occurred during the follow-up. The overall estimated survival at 1, 5, and 10 years was 93.1 ± 1.3%, 87.1 ± 1.9%, and 81.1 ± 3.4%. Reoperation was necessary in 14 (3.3%) patients. The overall freedom from MV reoperation at 1, 5, and 10 years was 98.2 ± 0.7%, 96.1 ± 1.2%, and 86.7 ± 6.7% and the overall freedom from recurrent MV regurgitation > grade 2 in repaired valves at 1, 5, and 10 years was 98.8 ± 0.6%, 98.8 ± 0.6%, and 94.6 ± 3.3%. Conclusions: Minimally invasive MV surgery via PUS can be performed with particularly good early and late results. Thus, the PUS approach with the use of standard surgical instruments and cannulation techniques can be a valuable option for the MV surgery either in patients contraindicated or not suitable to minithoracotomy.
Keywords	minimally invasive surgery ; mitral valve surgery ; partial upper sternotomy ; Medicine (General) ; R5-920
Subject code	616
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Treatment of Complex Two-Vessel Coronary Heart Disease with Single Left Internal Mammary Artery as T-Graft with Itself-A Retrospective Double Center Analysis of Short-Term Outcomes.

Rustenbach, Christian Jörg / Djordjevic, Ilija / Eghbalzadeh, Kaveh / Baumbach, Hardy / Wendt, Stefanie / Radwan, Medhat / Marinos, Spiro Lukas / Mustafi, Migdat / Lescan, Mario / Berger, Rafal / Salewski, Christoph / Sandoval Boburg, Rodrigo / Steger, Volker / Nemeth, Attila / Reichert, Stefan / Wahlers, Thorsten / Schlensak, Christian

Medicina (Kaunas, Lithuania)

2022 Volume 58, Issue 10

Abstract: Background and ... ...

Abstract	Background and Objectives
MeSH term(s)	Humans ; Mammary Arteries/transplantation ; Coronary Artery Disease/surgery ; Retrospective Studies ; Percutaneous Coronary Intervention ; Coronary Artery Bypass/methods ; Treatment Outcome
Language	English
Publishing date	2022-10-09
Publishing country	Switzerland
Document type	Review ; Journal Article
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina58101415
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Article ; Online: The impact of 3D printed models on spatial orientation in echocardiography teaching

Christoph Salewski / Attila Nemeth / Rodrigo Sandoval Boburg / Rafal Berger / Hasan Hamdoun / Hannes Frenz / Sebastian Spintzyk / Julia Kelley Hahn / Christian Schlensak / Tobias Krüger

BMC Medical Education, Vol 22, Iss 1, Pp 1-

2022 Volume 10

Abstract: Highlights • Medical students present difficulty with spatial orientation in echocardiography. • We asked for anatomical structures, 2D orientation, and 3D orientation. • We used 3D printed models for teaching standard echocardiographic views. • The 3D ... ...

Abstract	Highlights • Medical students present difficulty with spatial orientation in echocardiography. • We asked for anatomical structures, 2D orientation, and 3D orientation. • We used 3D printed models for teaching standard echocardiographic views. • The 3D group (n = 77) performed significantly better than the control group (n = 76). • We advocate 3D printed models for the teaching of echocardiography standard views.
Keywords	Echocardiography ; Cardiac surgery ; Cardiology ; 3D printing ; Teaching echocardiography ; Special aspects of education ; LC8-6691 ; Medicine ; R
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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