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  1. Article ; Online: EEG diagnosis of nonconvulsive status epilepticus: generalized periodic patterns--status or not?

    Korabathina, Kalyani / Benbadis, Selim R

    Expert review of neurotherapeutics

    2007  Volume 7, Issue 12, Page(s) 1643–1644

    MeSH term(s) Brain Diseases/pathology ; Diagnosis, Differential ; Electroencephalography ; Humans ; Male ; Middle Aged ; Status Epilepticus/diagnosis
    Language English
    Publishing date 2007-12
    Publishing country England
    Document type Case Reports ; Editorial ; Review
    ZDB-ID 2112534-X
    ISSN 1744-8360 ; 1473-7175
    ISSN (online) 1744-8360
    ISSN 1473-7175
    DOI 10.1586/14737175.7.12.1643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Levetiracetam is as effective as carbamazepine in newly diagnosed epilepsy.

    Korabathina, Kalyani / Benbadis, Selim R

    Expert review of neurotherapeutics

    2007  Volume 7, Issue 6, Page(s) 599–601

    Abstract: Evaluation of: Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke HJ. Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology 6, 402-408 (2007). Despite the emergence of multiple antiepileptic drugs ( ... ...

    Abstract Evaluation of: Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke HJ. Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology 6, 402-408 (2007). Despite the emergence of multiple antiepileptic drugs (AEDs) in the past decade, the task of choosing the right drug for monotherapy in patients with newly diagnosed epilepsy remains a precarious task. This is especially true when trying to choose a new AED over a more traditional agent. Much of this uncertainty stems from the fact that there are only a handful of studies that are able to demonstrate efficacy of a new drug over an older AED. While the newer drugs appear more favorable because of better tolerability, safety profiles and simple pharmacokinetics, many do not have an indication for monotherapy. Of course, this is further contingent upon the stringent limitations placed by regulatory bodies, such as the US FDA, who govern approval of AEDs for monotherapy. The current randomized study attempts to evaluate the efficacy of levetiracetam in monotherapy compared with controlled-release carbamazepine, a gold standard in patients with newly diagnosed epilepsy.
    Language English
    Publishing date 2007-06
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2112534-X
    ISSN 1744-8360 ; 1473-7175
    ISSN (online) 1744-8360
    ISSN 1473-7175
    DOI 10.1586/14737175.7.6.599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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