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  1. Book: Color atlas of genetics

    Passarge, Eberhard

    2018  

    Author's details Eberhard Passarge
    Keywords Atlas ; Genetics ; EBook ; Humangenetik
    Subject Medizinische Genetik ; Anthropogenetik ; Mensch ; Medizin
    Subject code 610
    Language English
    Size XI, 461 Seiten, Illustrationen
    Edition Fifth edition, revised and updated
    Publisher Thieme
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    Old title Vorangegangen ist
    HBZ-ID HT019830130
    ISBN 978-3-13-241440-2 ; 3-13-241440-9 ; 9783132414419 ; 3132414417
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 A 231 available for loan (reading room) Lesesaal EG

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  2. Book: Color atlas of genetics

    Passarge, Eberhard

    (Thieme flexibook ; Basic sciences)

    2013  

    Author's details Eberhard Passarge
    Series title Thieme flexibook
    Basic sciences
    Keywords Genetics, Medical ; Humangenetik
    Subject Medizinische Genetik ; Anthropogenetik ; Mensch ; Medizin
    Language English
    Size XI, 475 S. : zahlr. Ill., graph. Darst.
    Edition 4. ed., rev. and updated
    Publisher Thieme
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017274771
    ISBN 978-3-13-100364-5 ; 3-13-100364-2 ; 9783131645241 ; 3131645245
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 9949 order for loan Magazin
    2012 A 4853 order for loan Magazin

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  3. Article ; Online: Thalidomid-Embryopathie 60 Jahre.

    Passarge, Eberhard

    Deutsche medizinische Wochenschrift (1946)

    2022  Volume 147, Issue 24-25, Page(s) 1635–1638

    Abstract: This review describes the recognition and effects of thalidomide as a potent teratogenic agent sixty years ago. A systematic analysis revealed a broad spectrum of multiple congenital birth defects involving many organ systems. More than 5000 affected ... ...

    Title translation Thalidomide embryopathy 60 years.
    Abstract This review describes the recognition and effects of thalidomide as a potent teratogenic agent sixty years ago. A systematic analysis revealed a broad spectrum of multiple congenital birth defects involving many organ systems. More than 5000 affected individuals have been observed in Germany, more than 10 000 globally. Today about 2400 adults live with chronic late manifestations. In contrast to Europe and Canada, the thalidomide embryopathy did not occur in the United States of America: A physician responsible at the FDA had noted inconsistencies in the description of thalidomide. The GDR, too, did not market the drug.
    Language German
    Publishing date 2022-12-05
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1951-0792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Origins of human genetics. A personal perspective.

    Passarge, Eberhard

    European journal of human genetics : EJHG

    2021  Volume 29, Issue 7, Page(s) 1038–1044

    Abstract: Genetics evolved as a field of science after 1900 with new theories being derived from experiments obtained in fruit flies, bacteria, and viruses. This personal account suggests that the origins of human genetics can best be traced to the years 1949 to ... ...

    Abstract Genetics evolved as a field of science after 1900 with new theories being derived from experiments obtained in fruit flies, bacteria, and viruses. This personal account suggests that the origins of human genetics can best be traced to the years 1949 to 1959. Several genetic scientific advances in genetics in 1949 yielded results directly relating to humans for the first time, except for a few earlier observations. In 1949 the first textbook of human genetics was published, the American Journal of Human Genetics was founded, and in the previous year the American Society of Human Genetics. In 1940 in Britain a textbook entitled Introduction to Medical Genetics served as a foundation for introducing genetic aspects into medicine. The introduction of new methods for analyzing chromosomes and new biochemical assays using cultured cells in 1959 and subsequent years revealed that many human diseases, including cancer, have genetic causes. It became possible to arrive at a precise cause-related genetic diagnosis. As a result the risk of occurrence or re-occurrence of a disease within a family could be assessed correctly. Genetic counseling as a new concept became a basis for improved patient care. Taken together the advances in medically orientated genetic research and patient care since 1949 have resulted in human genetics being both, a basic medical and a basic biological science. Prior to 1949 genetics was not generally viewed in a medical context. Although monogenic human diseases were recognized in 1902, their occurrence and distribution were considered mainly at the population level.
    MeSH term(s) Alleles ; Biomedical Research/history ; Genetic Association Studies/history ; Genetic Association Studies/methods ; Genetic Association Studies/trends ; Genetic Diseases, Inborn/diagnosis ; Genetic Diseases, Inborn/genetics ; Genetic Diseases, Inborn/therapy ; Genetic Predisposition to Disease ; Genetics, Medical/history ; Genetics, Medical/trends ; History, 20th Century ; Humans
    Language English
    Publishing date 2021-02-04
    Publishing country England
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 1141470-4
    ISSN 1476-5438 ; 1018-4813
    ISSN (online) 1476-5438
    ISSN 1018-4813
    DOI 10.1038/s41431-020-00785-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3589: Show issues Location:
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  5. Article: Thalidomid-Embryopathie 60 Jahre

    Passarge, Eberhard

    DMW - Deutsche Medizinische Wochenschrift

    2022  Volume 147, Issue 24/25, Page(s) 1635–1638

    Abstract: Diese Rückschau beschreibt die wesentlichen Vorgänge bei der Erkennung der Thalidomid-Embryopathie vor rund 60 Jahren. Die systematische Analyse eines breiten Spektrums von angeborenen Fehlbildungen zahlreicher Organsysteme definiert dieses von 1959 bis ... ...

    Abstract Diese Rückschau beschreibt die wesentlichen Vorgänge bei der Erkennung der Thalidomid-Embryopathie vor rund 60 Jahren. Die systematische Analyse eines breiten Spektrums von angeborenen Fehlbildungen zahlreicher Organsysteme definiert dieses von 1959 bis 1962 gehäuft aufgetretene Krankheitsbild. Mehr als 5000 geschädigte Menschen wurden in der Bundesrepublik Deutschland beobachtet, weltweit mindestens 10 000. Heute leben in Deutschland noch etwa 2400 betroffene Erwachsene. Zahlreiche Spätfolgen mit chronischen Schmerzzuständen führen zu verminderter Lebensqualität. Im Gegensatz zu Europa und Kanada trat in den USA die Thalidomid-Embryopathie nicht gehäuft auf. Eine aufmerksame Ärztin am FDA verhinderte die Zulassung. Auch in der DDR wurde Thalidomid nicht vertrieben.
    Keywords Thalidomid ; Contergan ; Embryopathie ; Fehlbildungen ; thalidomide ; contergan ; embryopathy ; malformations ; birth defects
    Language German
    Publishing date 2022-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1951-0792
    Database Thieme publisher's database

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  6. Article ; Online: James L. German, a pioneer in early human genetic research turned 90.

    Passarge, Eberhard

    American journal of medical genetics. Part A

    2016  Volume 170, Issue 6, Page(s) 1564–1565

    Abstract: In the early 1960s, J. German established the non-synchronous human DNA replication pattern in metaphases of cultured lymphocytes and fibroblasts. This could be used to distinguish several chromosomes of similar morphology. From 1965 on over the next 30 ... ...

    Abstract In the early 1960s, J. German established the non-synchronous human DNA replication pattern in metaphases of cultured lymphocytes and fibroblasts. This could be used to distinguish several chromosomes of similar morphology. From 1965 on over the next 30 years, he and his coworkers systematically studied Bloom's syndrome in depth, cumulating in the identification in 1995 of the BLM gene as encoding a DNA helicase. © 2016 Wiley Periodicals, Inc.
    MeSH term(s) Bloom Syndrome/diagnosis ; Bloom Syndrome/genetics ; Bloom Syndrome/history ; DNA Replication ; Famous Persons ; Genetic Research/history ; Genetics, Medical/history ; History, 20th Century ; Humans ; RecQ Helicases/genetics ; United States
    Chemical Substances Bloom syndrome protein (EC 3.6.1.-) ; RecQ Helicases (EC 3.6.4.12)
    Language English
    Publishing date 2016-03-26
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 1493479-6
    ISSN 1552-4833 ; 1552-4825
    ISSN (online) 1552-4833
    ISSN 1552-4825
    DOI 10.1002/ajmg.a.37635
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Die EU-Konsultation zum Schutz von Hinweisgebern

    Passarge, Malte

    ZRFC : risk, fraud & compliance : Prävention und Aufdeckung in der Compliance-Organisation Vol. 12, No. 3 , p. 132-137

    eine Stellungsnahme von Pro Honore e.V

    2017  Volume 12, Issue 3, Page(s) 132–137

    Author's details Dr. Malte Passarge
    Language German
    Publisher E. Schmidt
    Publishing place Berlin
    Document type Article
    ZDB-ID 2479887-3
    ISSN 1867-8386
    Database ECONomics Information System

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  8. Article ; Online: In memoriam James L. German, a pioneer in early human genetic research.

    Groden, Joanna / Passarge, Eberhard

    American journal of medical genetics. Part A

    2018  Volume 176, Issue 12, Page(s) 2543–2544

    MeSH term(s) Famous Persons ; Genetic Research/history ; History, 20th Century ; History, 21st Century ; Humans
    Language English
    Publishing date 2018-10-05
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 1493479-6
    ISSN 1552-4833 ; 1552-4825
    ISSN (online) 1552-4833
    ISSN 1552-4825
    DOI 10.1002/ajmg.a.40513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: ALLGEMEINMEDIZINISCHES PRAKTIKUM

    Passarge, Edgar

    MIT BEISPIELEN FUER ERSTSEMESTER ZUR VORBEREITUNG FUER D. FAMULATUR

    1983  

    Author's details EDGAR PASSARGE
    Keywords FAMILY PRACTICE / CASE STUDIES ; Allgemeinmedizin ; Praktikum
    Size 175 S.
    Publisher BLAESCHKE
    Publishing place SANKT MICHAEL
    Document type Book
    HBZ-ID HT002569238
    ISBN 3-7053-1855-1 ; 978-3-7053-1855-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1985 B 635 order for loan Magazin

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  10. Article: Is icic inflammation an independent clinical Picture?

    PASSARGE, E

    Deutsche medizinische Wochenschrift (1946)

    2007  Volume 73, Issue 37-38, Page(s) 438

    Title translation Ist die Ilicardrüsenentzündung ein selbständiges Krankheitsbild?
    MeSH term(s) Embolism ; Humans
    Language German
    Publishing date 2007-12-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0028-1118175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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