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  1. Book ; Thesis: Ecology, vegetation and soil seed bank studies of Sundarban mangrove forest in Bangladesh

    Rashid, Harun-or

    (Berichte des Institutes für Landschafts- und Pflanzenökologie der Universität Hohenheim : Beiheft ; 21)

    2007  

    Author's details Sheikh Harun-or-Rashid
    Series title Berichte des Institutes für Landschafts- und Pflanzenökologie der Universität Hohenheim : Beiheft ; 21
    Berichte des Institutes für Landschafts- und Pflanzenökologie der Universität Hohenheim
    Berichte des Institutes für Landschafts- und Pflanzenökologie der Universität Hohenheim ; Beiheft
    Collection Berichte des Institutes für Landschafts- und Pflanzenökologie der Universität Hohenheim
    Berichte des Institutes für Landschafts- und Pflanzenökologie der Universität Hohenheim ; Beiheft
    Language English
    Size 156 S. : Ill., graph. Darst.
    Publisher Univ. Hohenheim, Inst. für Landschafts- und Pflanzenökologie
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hohenheim, Univ., Diss., 2007
    Note Zsfassung in dt. Sprache
    HBZ-ID HT015350602
    ISBN 9783991159516 ; 978-3-9811595-1-6 ; 3-9811595-1-9 ; 3991159511
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Article ; Online: FERARI and cargo adaptors coordinate cargo flow through sorting endosomes

    Jachen A. Solinger / Harun-Or Rashid / Anne Spang

    Nature Communications, Vol 13, Iss 1, Pp 1-

    2022  Volume 17

    Abstract: It is estimated that about 80% of endocytosed material is recycled back to the plasma membrane. Here, the authors show that kiss-and-run of Rab5 early endocytic and Rab11 recycling vesicles on sorting endosomes allow cargo flow, providing more robustness ...

    Abstract It is estimated that about 80% of endocytosed material is recycled back to the plasma membrane. Here, the authors show that kiss-and-run of Rab5 early endocytic and Rab11 recycling vesicles on sorting endosomes allow cargo flow, providing more robustness and fidelity to the sorting process.
    Keywords Science ; Q
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Magnetically Driven Biopsy Capsule Robot with Spring Mechanism.

    Rashid, Md Harun Or / Lin, Feng

    Micromachines

    2024  Volume 15, Issue 2

    Abstract: In recent years, capsule endoscopes (CEs) have appeared as an advanced technology for the diagnosis of gastrointestinal diseases. However, only capturing the images limits the advanced diagnostic procedures and so on in CE's applications. Herein, ... ...

    Abstract In recent years, capsule endoscopes (CEs) have appeared as an advanced technology for the diagnosis of gastrointestinal diseases. However, only capturing the images limits the advanced diagnostic procedures and so on in CE's applications. Herein, considering other extended functions like tissue sampling, a novel wireless biopsy CE has been presented employing active locomotion. Two permanent magnets (PMs) have been placed into the robots, which control the actuation of the capsule robot (CR) and biopsy mechanism by employing an external electromagnetic actuation (EMA) system. A spring has been attached to the biopsy mechanism to retract the biopsy tool after tissue collection. A camera module has also been attached to the front side of the CR to detect the target point and observe the biopsy process on the lesion. A prototype of CR was fabricated with a diameter of 12 mm and a length of 32 mm. A spring mechanism with a biopsy needle was placed inside the CR and sprang out around 5 mm. An in vitro experiment was conducted, which demonstrated the precise control translation (2 mm/s and 3 mm/s in the x and y directions, respectively) and desired extrusion of the biopsy mechanism (~5 mm) for sampling the tissue. A needle-based biopsy capsule robot (NBBCR) has been designed to perform the desired controlled locomotion and biopsy function by external force. This proposed active locomoted untethered NBBCR can be wirelessly controlled to perform extended function precisely, advancing the intestinal CE technique for clinical applications.
    Language English
    Publishing date 2024-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15020287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: FERARI and cargo adaptors coordinate cargo flow through sorting endosomes.

    Solinger, Jachen A / Rashid, Harun-Or / Spang, Anne

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 4620

    Abstract: ... the fate of proteins: recycling, secretion or degradation. FERARI (Factors for Endosome Recycling and Rab ...

    Abstract Cellular organization, compartmentalization and cell-to-cell communication are crucially dependent on endosomal pathways. Sorting endosomes provide a transit point for various trafficking pathways and decide the fate of proteins: recycling, secretion or degradation. FERARI (Factors for Endosome Recycling and Rab Interactions) play a key role in shaping these compartments and coordinate Rab GTPase function with membrane fusion and fission of vesicles through a kiss-and-run mechanism. Here, we show that FERARI also mediate kiss-and-run of Rab5-positive vesicles with sorting endosomes. During these encounters, cargo flows from Rab5-positive vesicles into sorting endosomes and from there in Rab11-positive vesicles. Cargo flow from sorting endosomes into Rab11 structures relies on the cargo adaptor SNX6, while cargo retention in the Rab11 compartment is dependent on AP1. The available cargo amount appears to regulate the duration of kisses. We propose that FERARI, together with cargo adaptors, coordinate the vectorial flow of cargo through sorting endosomes.
    MeSH term(s) Cell Communication ; Endosomes/metabolism ; Membrane Fusion ; Protein Transport ; rab GTP-Binding Proteins/metabolism
    Chemical Substances rab GTP-Binding Proteins (EC 3.6.5.2)
    Language English
    Publishing date 2022-08-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-32377-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: FERARI is required for Rab11-dependent endocytic recycling.

    Solinger, Jachen A / Rashid, Harun-Or / Prescianotto-Baschong, Cristina / Spang, Anne

    Nature cell biology

    2020  Volume 22, Issue 2, Page(s) 213–224

    Abstract: ... secretion or degradation of proteins. The organization of these processes requires membrane-tethering ...

    Abstract Endosomal transport is essential for cellular organization and compartmentalization and cell-cell communication. Sorting endosomes provide a crossroads for various trafficking pathways and determine recycling, secretion or degradation of proteins. The organization of these processes requires membrane-tethering factors to coordinate Rab GTPase function with membrane fusion. Here, we report a conserved tethering platform that acts in the Rab11 recycling pathways at sorting endosomes, which we name factors for endosome recycling and Rab interactions (FERARI). The Rab-binding module of FERARI consists of Rab11FIP5 and rabenosyn-5/RABS-5, while the SNARE-interacting module comprises VPS45 and VIPAS39. Unexpectedly, the membrane fission protein EHD1 is also a FERARI component. Thus, FERARI appears to combine fusion activity through the SM protein VPS45 with pinching activity through EHD1 on SNX-1-positive endosomal membranes. We propose that coordination of fusion and pinching through a kiss-and-run mechanism drives cargo at endosomes into recycling pathways.
    MeSH term(s) Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Cell Communication ; Endocytosis/genetics ; Endosomes/metabolism ; Gene Expression Regulation ; HEK293 Cells ; HeLa Cells ; Humans ; Intestines/cytology ; Molecular Imaging ; Oocytes/cytology ; Oocytes/metabolism ; Protein Transport ; Sorting Nexins/genetics ; Sorting Nexins/metabolism ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism
    Chemical Substances Adaptor Proteins, Signal Transducing ; Caenorhabditis elegans Proteins ; EHD1 protein, human ; RAB11FIP5 protein, human ; RBSN protein, human ; RME-1 protein, C elegans ; SNX-1 protein, C elegans ; Sorting Nexins ; VIPAS39 protein, human ; VPS45 protein, human ; Vesicular Transport Proteins
    Language English
    Publishing date 2020-01-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1474722-4
    ISSN 1476-4679 ; 1465-7392
    ISSN (online) 1476-4679
    ISSN 1465-7392
    DOI 10.1038/s41556-019-0456-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Diaphragm ultrasound as a better predictor of successful extubation from mechanical ventilation than rapid shallow breathing index.

    Alam, Mohammad Jhahidul / Roy, Simanta / Iktidar, Mohammad Azmain / Padma, Fahmida Khatun / Nipun, Khairul Islam / Chowdhury, Sreshtha / Nath, Ranjan Kumar / Rashid, Harun-Or

    Acute and critical care

    2022  Volume 37, Issue 1, Page(s) 94–100

    Abstract: Background: In 3%-19% of patients, reintubation is needed 48-72 hours following extubation, which increases intensive care unit (ICU) morbidity, mortality, and expenses. Extubation failure is frequently caused by diaphragm dysfunction. Ultrasonography ... ...

    Abstract Background: In 3%-19% of patients, reintubation is needed 48-72 hours following extubation, which increases intensive care unit (ICU) morbidity, mortality, and expenses. Extubation failure is frequently caused by diaphragm dysfunction. Ultrasonography can be used to determine the mobility and thickness of the diaphragm. This study looked at the role of diaphragm excursion (DE) and thickening fraction in predicting successful extubation from mechanical ventilation.
    Methods: Thirty-one patients were extubated with the advice of an ICU consultant using the ICU weaning regimen and diaphragm ultrasonography was performed. Ultrasound DE and thickening fraction were measured three times: at the commencement of the t-piece experiment, at 10 minutes, and immediately before extubation. All patients' parameters were monitored for 48 hours after extubation. Rapid shallow breathing index (RSBI) was also measured at the same time.
    Results: Successful extubation was significantly correlated with DE (P=0.01). Receiver curve analysis for DE to predict successful extubation revealed good properties (area under the curve [AUC], 0.83; P<0.001); sensitivity, 77.8%; specificity, 84.6%, positive predictive value (PPV), 87.5%; negative predictive value (NPV), 73.3% while cut-off value, 11.43 mm. Diaphragm thickening fraction (DTF) also revealed moderate curve properties (AUC, 0.69; P=0.06); sensitivity, 61.1%; specificity, 84.6%; PPV, 87.5%; NPV, 61.1% with cut-off value 22.33% although former one was slightly better. RSBI could not reach good receiver operating characteristic value at cut-off points 100 b/min/L (AUC, 0.58; P=0.47); sensitivity, 66.7%; specificity, 53.8%; PPV, 66.7%; NPV, 53.8%).
    Conclusions: To decrease the rate of reintubation, DE and DTF are better indicators of successful extubation. DE outperforms DTF.
    Language English
    Publishing date 2022-01-11
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3003021-3
    ISSN 2586-6060 ; 2586-6052
    ISSN (online) 2586-6060
    ISSN 2586-6052
    DOI 10.4266/acc.2021.01354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Reduced Flavin in Aqueous Solution Is Nonfluorescent.

    McBride, Rylee A / Barnard, David T / Jacoby-Morris, Kimberly / Harun-Or-Rashid, Md / Stanley, Robert J

    Biochemistry

    2023  Volume 62, Issue 3, Page(s) 759–769

    Abstract: Flavins are blue-light-absorbing chromophores with rich redox activity. Biologically, the most important are riboflavin (vitamin ... ...

    Abstract Flavins are blue-light-absorbing chromophores with rich redox activity. Biologically, the most important are riboflavin (vitamin B
    MeSH term(s) Flavins/metabolism ; Riboflavin ; Oxidation-Reduction ; Electron Transport ; Flavin-Adenine Dinucleotide/chemistry ; Flavin Mononucleotide/chemistry ; Organic Chemicals
    Chemical Substances 4,6-dinitro-o-cresol (1604ZJR09T) ; Flavins ; Riboflavin (TLM2976OFR) ; Flavin-Adenine Dinucleotide (146-14-5) ; Flavin Mononucleotide (7N464URE7E) ; Organic Chemicals
    Language English
    Publishing date 2023-01-23
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1108-3
    ISSN 1520-4995 ; 0006-2960
    ISSN (online) 1520-4995
    ISSN 0006-2960
    DOI 10.1021/acs.biochem.2c00538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Carbon Nanotube Membranes

    Md. Harun-Or Rashid / Stephen F. Ralph

    Nanomaterials, Vol 7, Iss 5, p

    Synthesis, Properties, and Future Filtration Applications

    2017  Volume 99

    Abstract: ... of aqueous solutions containing organic compounds and/or bacteria, and the separation of individual liquids ...

    Abstract Over the course of the past decade, there has been growing interest in the development of different types of membranes composed of carbon nanotubes (CNTs), including buckypapers and composite materials, for an ever-widening range of filtration applications. This article provides an overview of how different types of CNT membranes are prepared and the results obtained from investigations into their suitability for different applications. The latter involve the removal of small particles from air samples, the filtration of aqueous solutions containing organic compounds and/or bacteria, and the separation of individual liquids present in mixtures. A growing number of reports have demonstrated that the incorporation of CNTs into composite membranes confers an improved resistance to fouling caused by biomacromolecules and bacteria. These results are discussed, along with evidence that demonstrates it is possible to further reduce fouling by taking advantage of the inherent conductivity of composite membranes containing CNTs, as well as by using different types of electrochemical stimuli.
    Keywords carbon nanotubes ; buckypapers ; fouling ; permeability ; pervaporation ; desalination ; Chemistry ; QD1-999
    Subject code 620
    Language English
    Publishing date 2017-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination.

    Juilland, Mélanie / Alouche, Nagham / Ubezzi, Ivana / Gonzalez, Montserrat / Rashid, Harun-Or / Scarpellino, Leonardo / Erdmann, Tabea / Grau, Michael / Lenz, Georg / Luther, Sanjiv A / Thome, Margot

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 52, Page(s) e2301155120

    Abstract: The protease MALT1 promotes lymphocyte activation and lymphomagenesis by cleaving a limited set of cellular substrates, most of which control gene expression. Here, we identified the integrin-binding scaffold protein Tensin-3 as a MALT1 substrate in ... ...

    Abstract The protease MALT1 promotes lymphocyte activation and lymphomagenesis by cleaving a limited set of cellular substrates, most of which control gene expression. Here, we identified the integrin-binding scaffold protein Tensin-3 as a MALT1 substrate in activated human B cells. Activated B cells lacking Tensin-3 showed decreased integrin-dependent adhesion but exhibited comparable NF-κB1 and Jun N-terminal kinase transcriptional responses. Cells expressing a noncleavable form of Tensin-3, on the other hand, showed increased adhesion. To test the role of Tensin-3 cleavage in vivo, mice expressing a noncleavable version of Tensin-3 were generated, which showed a partial reduction in the T cell-dependent B cell response. Interestingly, human diffuse large B cell lymphomas and mantle cell lymphomas with constitutive MALT1 activity showed strong constitutive Tensin-3 cleavage and a decrease in uncleaved Tensin-3 levels. Moreover, silencing of Tensin-3 expression in MALT1-driven lymphoma promoted dissemination of xenografted lymphoma cells to the bone marrow and spleen. Thus, MALT1-dependent Tensin-3 cleavage reveals a unique aspect of the function of MALT1, which negatively regulates integrin-dependent B cell adhesion and facilitates metastatic spread of B cell lymphomas.
    MeSH term(s) Mice ; Humans ; Animals ; Adult ; Tensins/genetics ; Caspases/metabolism ; NF-kappa B/metabolism ; Cell Adhesion/genetics ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein/genetics ; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein/metabolism ; Lymphoma, Large B-Cell, Diffuse/genetics ; Integrins
    Chemical Substances Tensins ; Caspases (EC 3.4.22.-) ; NF-kappa B ; Neoplasm Proteins ; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein (EC 3.4.22.-) ; Integrins ; MALT1 protein, human (EC 3.4.22.-)
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2301155120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Serum oxidative biomarkers associated with genital HPV infection and cervical lesions in women.

    Lin, Hui-Yi / Zhu, Xiaodan / Mazumder, Harun Or Rashid / Ronis, Martin / Pedersen, Kim Brint / Hagensee, Michael

    Journal of medical virology

    2024  Volume 96, Issue 1, Page(s) e29362

    Abstract: Human papillomavirus (HPV) infection is a major cause of cervical cancer. Studies showed HPV carcinogenesis may be induced by oxidative stress affecting the host immune system. The objective of this study is to evaluate levels of four circulating ... ...

    Abstract Human papillomavirus (HPV) infection is a major cause of cervical cancer. Studies showed HPV carcinogenesis may be induced by oxidative stress affecting the host immune system. The objective of this study is to evaluate levels of four circulating oxidative stress biomarkers associated with the HPV infection, persistence, and cervical lesion status in women. The three serum biomarkers measuring oxidative damage to biomolecules (8-oxodG, 8-oxo-7,8-dihydro-2'-deoxyguanosine [8-oxodG] for DNA, 4-hydroxy-2-nonenal [4-HNE] for lipid, and protein carbonyl [PC] for protein) and one antioxidant (glutathione, GSH) collected from 38 women were evaluated. The PC levels were significantly higher for women with oncogenic HPV infection (p = 0.047) and persistence (p = 0.053) based on the unadjusted linear model. In particular, women with ≥3 oncogenic HPV types had a higher PC level than those without HPV infection (p = 0.041). Women with low-grade squamous intraepithelial lesions showed an elevated PC (p = 0.058). These trends remained similar after adjusting for age. The GSH levels were lower for women infected with ≥3 oncogenic HPV types based on age-adjusted results (p = 0.061). This study supported that serum PC was associated with HPV infection, persistence, and cervical lesions, so it can potentially be used to monitor HPV carcinogenesis. Further large-scale studies will be needed to confirm these findings.
    MeSH term(s) Female ; Humans ; Papillomavirus Infections/complications ; 8-Hydroxy-2'-Deoxyguanosine ; Sexually Transmitted Diseases ; Biomarkers ; Carcinogenesis ; Glutathione ; Oxidative Stress ; Genitalia
    Chemical Substances 8-Hydroxy-2'-Deoxyguanosine (88847-89-6) ; Biomarkers ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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