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  1. Article ; Online: Fructokinase Inhibition to Prevent Kidney Disease.

    Ducloux, Didier

    Clinical journal of the American Society of Nephrology : CJASN

    2024  

    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.0000000000000442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: REGEN-Cov antibody combination to prevent COVID-19 infection in kidney transplant recipient without detectable antibody response to optimal vaccine scheme.

    Ducloux, Didier / Courivaud, Cécile

    Kidney international

    2022  Volume 101, Issue 3, Page(s) 645–646

    MeSH term(s) Antibodies, Monoclonal, Humanized ; Antibodies, Neutralizing ; Antibody Formation ; COVID-19 ; COVID-19 Vaccines ; Drug Combinations ; Humans ; Kidney Transplantation ; SARS-CoV-2 ; Transplant Recipients
    Chemical Substances Antibodies, Monoclonal, Humanized ; Antibodies, Neutralizing ; COVID-19 Vaccines ; Drug Combinations ; casirivimab and imdevimab drug combination
    Language English
    Publishing date 2022-01-04
    Publishing country United States
    Document type Letter
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.12.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Prevention of Post-Transplant Diabetes Mellitus: Towards a Personalized Approach.

    Ducloux, Didier / Courivaud, Cécile

    Journal of personalized medicine

    2022  Volume 12, Issue 1

    Abstract: Post-transplant diabetes is a frequent complication after transplantation. Moreover, patients suffering from post-transplant diabetes have increased cardiovascular morbidity and reduced survival. Pathogenesis mainly involves beta-cell dysfunction in ... ...

    Abstract Post-transplant diabetes is a frequent complication after transplantation. Moreover, patients suffering from post-transplant diabetes have increased cardiovascular morbidity and reduced survival. Pathogenesis mainly involves beta-cell dysfunction in presence of insulin resistance. Both pre- and post-transplant risk factors are well-described, and some of them may be corrected or prevented. However, the frequency of post-transplant diabetes has not decreased in recent years. We realized a critical appraisal of preventive measures to reduce post-transplant diabetes.
    Language English
    Publishing date 2022-01-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm12010116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Should vaccination against COVID-19 be mandated in patients on the transplant waiting list?

    Ducloux, Didier / Courivaud, Cécile

    Kidney international

    2021  Volume 100, Issue 4, Page(s) 939–940

    MeSH term(s) COVID-19 ; Humans ; Kidney Transplantation ; SARS-CoV-2 ; Vaccination ; Waiting Lists
    Language English
    Publishing date 2021-07-30
    Publishing country United States
    Document type Letter
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2021.07.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prevention of Post-Transplant Diabetes Mellitus

    Didier Ducloux / Cécile Courivaud

    Journal of Personalized Medicine, Vol 12, Iss 116, p

    Towards a Personalized Approach

    2022  Volume 116

    Abstract: Post-transplant diabetes is a frequent complication after transplantation. Moreover, patients suffering from post-transplant diabetes have increased cardiovascular morbidity and reduced survival. Pathogenesis mainly involves beta-cell dysfunction in ... ...

    Abstract Post-transplant diabetes is a frequent complication after transplantation. Moreover, patients suffering from post-transplant diabetes have increased cardiovascular morbidity and reduced survival. Pathogenesis mainly involves beta-cell dysfunction in presence of insulin resistance. Both pre- and post-transplant risk factors are well-described, and some of them may be corrected or prevented. However, the frequency of post-transplant diabetes has not decreased in recent years. We realized a critical appraisal of preventive measures to reduce post-transplant diabetes.
    Keywords post-transplant diabetes ; kidney transplantation ; prevention ; Medicine ; R
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Pretransplant coronary artery disease screening is still valid.

    Ducloux, Didier / Rebibou, Jean-Michel / Courivaud, Cécile

    Kidney international

    2021  Volume 99, Issue 3, Page(s) 772

    MeSH term(s) Coronary Artery Disease/diagnostic imaging ; Humans ; Kidney Failure, Chronic ; Kidney Transplantation ; Propensity Score ; Transplant Recipients
    Language English
    Publishing date 2021-02-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2020.12.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Regulatory T cells and cancer: an undesired tolerance.

    Ducloux, Didier

    Kidney international

    2014  Volume 86, Issue 1, Page(s) 16–18

    Abstract: The incidence of cancer is markedly increased in organ transplant patients. A better understanding of underlying mechanisms and the identification of biomarkers for diagnosis and prognosis are major challenges. Hope et al. report expansion of regulatory ... ...

    Abstract The incidence of cancer is markedly increased in organ transplant patients. A better understanding of underlying mechanisms and the identification of biomarkers for diagnosis and prognosis are major challenges. Hope et al. report expansion of regulatory T cells to be associated with the presence and severity of cancer. Although relevant, these results raise several questions.
    MeSH term(s) Female ; Humans ; Kidney Transplantation/adverse effects ; Male ; Neoplasms/etiology ; Neoplasms/immunology ; T-Lymphocytes, Regulatory/immunology
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1038/ki.2014.46
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Triglyceride-Glucose Index and Cardiovascular Events in Kidney Transplant Recipients.

    Colladant, Mathilde / Chabannes, Melchior / Crepin, Thomas / Bamoulid, Jamal / Courivaud, Cécile / Ducloux, Didier

    Kidney international reports

    2023  Volume 8, Issue 11, Page(s) 2307–2314

    Abstract: Introduction: Kidney transplant recipients (KTRs) have an increased risk of cardiovascular (CV) events (CVEs) compared with the general population. The impact of insulin resistance on CV risk after transplantation is not well defined.: Methods: We ... ...

    Abstract Introduction: Kidney transplant recipients (KTRs) have an increased risk of cardiovascular (CV) events (CVEs) compared with the general population. The impact of insulin resistance on CV risk after transplantation is not well defined.
    Methods: We tested whether triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, may predict posttransplant CVEs in a cohort of 715 consecutive KTRs all included 1 year after transplant.
    Results: Follow-up was 9.1 ± 4.6 years. Mean TyG at inclusion was 4.75 ± 0.29 (median, 4.73 [4.14-5.84]). In multiple regression analysis, having a TyG above the median value was associated with higher body mass index (BMI), low high-density lipoprotein (HDL) cholesterol level, and greater urinary protein excretion. A total of 127 CVEs (17.7%) occurred during the study period. In univariate analysis, TyG was strongly associated with CVE occurrence (hazard ratio [HR] 2.06, 95% CI 1.42-3.50, for each increase of 0.1 in TyG,
    Conclusion: Insulin resistance, as measured by the TyG index is strongly associated with CVE in KTRs. Improving insulin sensitivity seems to be a major issue to prevent CV morbidity and mortality in this high-risk population.
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Journal Article
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2023.08.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Determinants of urgent start dialysis in a chronic kidney disease cohort followed by nephrologists.

    Tachikart, Amin / Vachey, Clément / Vauchy, Charline / Savet, Caroline / Ducloux, Didier / Courivaud, Cécile

    BMC nephrology

    2023  Volume 24, Issue 1, Page(s) 190

    Abstract: Background: The French Renal Epidemiology and Information Network (REIN) registry collect dialysis initiation context for each patient starting dialysis with a flawed definition of urgent start dialysis (USD). The main objective of this study was to ... ...

    Abstract Background: The French Renal Epidemiology and Information Network (REIN) registry collect dialysis initiation context for each patient starting dialysis with a flawed definition of urgent start dialysis (USD). The main objective of this study was to identify factors associated with USD in patients regularly followed-up by a nephrologist using a classification of USD considering the preparation to renal replacement therapy.
    Methods: This retrospective cohort study included adult patients who started dialysis between 2012 and 2018 in the Franche-Comté region of France after a minimum of two nephrology consultations. We classified dialysis initiation context as follows: USD for patients with no dialysis access (DA) created or planned, unplanned non urgent start dialysis (UNUSD) for patients starting with a recent or non-functional DA and planned start dialysis (PSD) for those starting with a functional and mature DA.
    Results: Four hundred and sixty-five patients met inclusion criteria. According to REIN registry, 94 (20.3%) patients were urgent starters (US) whereas with our classification 80 (17.2%) and 73 (15.7%) where respectively US and unplanned non urgent starters (UNUS). The factors independently associated with USD in our classification were: stroke (odds ratio(OR) = 2.76, 95% confidence interval (95%CI)=[1.41-5.43]), cardiac failure (OR = 1.78, 95%CI=[1.07-2.96]) and the number of nephrology consultations prior dialysis onset (OR = 0.73, 95%CI=[0.64-0.83]). Thirty-one patients died during the first year after dialysis start. According to our classification, we observed significantly different survival probabilities: 95.7%, 89.5% and 83.4% respectively for planned starters, UNUS and US (p = 0.001).
    Conclusion: The two factors independently associated with USD were cardiac failure and stroke.
    MeSH term(s) Adult ; Humans ; Renal Dialysis ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/therapy ; Nephrologists ; Retrospective Studies ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/therapy ; Heart Failure/epidemiology ; Heart Failure/therapy
    Language English
    Publishing date 2023-06-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041348-8
    ISSN 1471-2369 ; 1471-2369
    ISSN (online) 1471-2369
    ISSN 1471-2369
    DOI 10.1186/s12882-023-03222-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Factors associated with humoral response after BNT162b2 mRNA COVID-19 vaccination in kidney transplant patients.

    Ducloux, Didier / Colladant, Mathilde / Chabannes, Melchior / Bamoulid, Jamal / Courivaud, Cécile

    Clinical kidney journal

    2021  Volume 14, Issue 10, Page(s) 2270–2272

    Language English
    Publishing date 2021-07-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfab125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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