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  1. Article ; Online: Determinants of uptake of influenza, zoster and pneumococcal vaccines in patients with cardiovascular diseases.

    Benedict Kpozehouen, Elizabeth / Macintyre, C Raina / Tan, Timothy C

    Vaccine

    2024  

    Abstract: Background: Globally, cardiovascular disease (CVD) is the leading cause of death and illness. Vaccine-preventable infections may increase acute coronary vascular disease events and the risk of complications. Low vaccine coverage has been reported among ... ...

    Abstract Background: Globally, cardiovascular disease (CVD) is the leading cause of death and illness. Vaccine-preventable infections may increase acute coronary vascular disease events and the risk of complications. Low vaccine coverage has been reported among adults at high risk of complications from vaccine-preventable infections. There is a gap in research evidence around determinants of uptake of vaccines among adults with CVD. This study examined the uptake of influenza, pneumococcal and zoster vaccines and the determinants of uptake of the vaccines among cardiac patients.
    Method: A prospective cross-sectional study was carried out among hospitalised cardiac patients through an interviewer-administered questionnaire. Descriptive statistics were used to investigate self-reported uptake of influenza, pneumococcal and zoster vaccines. Univariate and multivariate analyses of participants' social demographic and clinical characteristics were conducted to identify factors for receiving influenza vaccine.
    Results: Low vaccination rates among 104 participants were found for influenza (45.2%), pneumococcal (13.5%) and zoster (5.8%) vaccines. The most common reason for not receiving influenza vaccine was concern about side effects. Lack of awareness about the pneumococcal and zoster vaccines was the main reason for the poor uptake of these vaccines. Australia-born participants were more likely to receive influenza vaccine than overseas-born participants. Working-age participants and, interestingly, people living with a current smoker were less likely to receive influenza vaccine.
    Conclusion: Influenza, pneumococcal and zoster vaccine uptake among cardiac patients was low. Encouraging physician recommendations for vaccination for cardiac patients under 65 years of age and addressing vaccination challenges among people from culturally and linguistically diverse backgrounds and pharmacy, workplace, and hospital vaccination may help increase vaccination uptake among cardiac patients.
    Language English
    Publishing date 2024-05-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2024.04.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: AngioCRIME in Acute Myeloid Leukemia (AML).

    Macintyre, Elizabeth

    HemaSphere

    2017  Volume 1, Issue 1, Page(s) e15

    Language English
    Publishing date 2017-12-20
    Publishing country United States
    Document type Editorial
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Precision hematology: Navigating the evolution of diagnostic classifications in the era of globalized medicine.

    Macintyre, Elizabeth / Döhner, Konstanze / Grønbæk, Kirsten / Dreyling, Martin / Huntly, Brian / Almeida, Antonio / Gribben, John

    HemaSphere

    2024  Volume 8, Issue 4, Page(s) e65

    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Editorial
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1002/hem3.65
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The EHA2021 Annual Congress Award Winners: Celebrating Excellence in Hematology.

    Gribben, John / Macintyre, Elizabeth / Sonneveld, Pieter

    HemaSphere

    2021  Volume 5, Issue 6, Page(s) e585

    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Editorial
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Uptake of influenza, pneumococcal and herpes zoster vaccines among people with heart failure and atrial fibrillation.

    Kpozehouen, Elizabeth Benedict / Tan, Timothy / Macintyre, Chandini Raina

    Vaccine

    2022  Volume 40, Issue 52, Page(s) 7709–7713

    Abstract: Background: Cardiovascular diseases are the major cause of hospitalisation and death globally. Infections exacerbate cardiovascular events among cardiac patients, contributing to all-cause mortality. Vaccination is a cheap and effective intervention ... ...

    Abstract Background: Cardiovascular diseases are the major cause of hospitalisation and death globally. Infections exacerbate cardiovascular events among cardiac patients, contributing to all-cause mortality. Vaccination is a cheap and effective intervention that can prevent infection. In Australia, influenza, pneumococcal and herpes zoster vaccines are recommended and funded for high-risk adults such as cardiac patients. There is high prevalence of high-risk adults in Western Sydney.
    Objectives: This study investigates the uptake of influenza, pneumococcal and herpes zoster vaccines in patients admitted with heart failure and atrial fibrillation in a tertiary hospital in Western Sydney and factors associated with the uptake of the vaccines.
    Methods: Consecutive patients' hospitalised between 2014 and 2018 with heart failure or atrial fibrillation as principal diagnoses were identified. Information on patients' social demographic, clinical and vaccination status was collected and described using descriptive analysis. Univariate and multivariate analyses were conducted to determine factors associated with the uptake of the vaccines.
    Results: Low uptake for pneumococcal (40-45 %) and herpes zoster (15 %) vaccines were found. Prevalence of influenza vaccination was lower among participants younger than 65 (51-72 %) than in older ones (78-96 %). Australia-born participants were more likely to receive pneumococcal vaccine than those born overseas (OR 2.02, 95 % CI 1.05-3.89). Participants 65 years or older and those with comorbidities such as hypertension, COPD and chronic renal impairment were more likely to receive the vaccines.
    Conclusion: Multidisciplinary strategies are needed to improve access to vaccination, community knowledge, community engagement, and healthcare provider support to provide appropriate care to migrants and younger cardiac patients and reduce morbidity and mortality in this high-risk group.
    MeSH term(s) Adult ; Humans ; Aged ; Herpes Zoster Vaccine ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Atrial Fibrillation/complications ; Pneumococcal Vaccines ; Influenza Vaccines ; Vaccination ; Streptococcus pneumoniae ; Herpes Zoster/epidemiology ; Herpes Zoster/prevention & control ; Heart Failure
    Chemical Substances Herpes Zoster Vaccine ; Pneumococcal Vaccines ; Influenza Vaccines
    Language English
    Publishing date 2022-11-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2022.10.090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Open Access is the Plan S Way Forward in Hematology Research.

    Cools, Jan / Engert, Andreas / Gribben, John / Macintyre, Elizabeth

    HemaSphere

    2020  Volume 4, Issue 1, Page(s) e331

    Language English
    Publishing date 2020-01-15
    Publishing country United States
    Document type Editorial
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Informing the design of a whole of life immunisation register for Australia.

    Kpozehouen, Elizabeth B / Heywood, Anita E / Menzies, Robert / Seale, Holly / Brotherton, Julia / Raina Macintyre, C

    Vaccine

    2023  Volume 41, Issue 19, Page(s) 3011–3018

    Abstract: Introduction: In 2016, Australia launched a whole life immunisation register, the Australian Immunisation Register (AIR), building on a universal childhood register established in 1997. Immunisation Information Systems are well established in Europe, ... ...

    Abstract Introduction: In 2016, Australia launched a whole life immunisation register, the Australian Immunisation Register (AIR), building on a universal childhood register established in 1997. Immunisation Information Systems are well established in Europe, the US and elsewhere. However, a national system covering immunisation across the lifespan, with complete capture of the population and satisfactory data quality, is rare.
    Methods: A national workshop was convened in 2016 with key stakeholders from the government, new and existing vaccine users, and vaccine providers to review the ideal features of the AIR to ensure optimal effectiveness. This workshop focused on the functionality needed to identify population groups newly included in the register and support the achievement of high immunisation coverage in these groups eligible for National Immunisation Program vaccines.
    Results: Key recommendations included the need for bidirectional data flow between the AIR and providers; systematic approaches to the capture and recording of accurate and complete data to ascertain important denominators for subpopulations, includingAboriginal and Torres Strait Islander status, medical risk factors, occupation, ethnicity, country of birth, and vaccines given during pregnancy; linkage with other government datasets including notifiable diseases; the capture of adverse events following immunisation; ease of access by patients, providers; and by researchers.
    Conclusions: Some recommendations from the workshop have informed the development and future utility of the AIR. Some recommendations from the workshop have been integrated into the current iteration of the AIR, which is more important than ever given the roll-out of COVID-19 vaccines. The accuracy and validity of data have subsequently improved through data entry controls, data integrity checks and reporting requirements. Access to AIR data for research remains protracted and costly, limitingresearch potential.
    MeSH term(s) Humans ; Child ; Australia/epidemiology ; COVID-19 Vaccines ; COVID-19/prevention & control ; Immunization ; Vaccines ; Immunization Programs
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2023-04-08
    Publishing country Netherlands
    Document type Clinical Conference
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.03.037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Knowledge, attitudes and practices of health care workers in a cardiology department on influenza vaccination.

    Benedict Kpozehouen, Elizabeth / Arrudsivah, Bravien / Tan, Timothy C / Raina Macintyre, C

    Vaccine

    2023  Volume 41, Issue 14, Page(s) 2349–2356

    Abstract: Background: Evidence has accrued that influenza vaccination may be effective in preventing myocardial infarction (MI). However, vaccination rates in both adults and health care workers (HCW) are low, and hospitalisation is often a missed opportunity for ...

    Abstract Background: Evidence has accrued that influenza vaccination may be effective in preventing myocardial infarction (MI). However, vaccination rates in both adults and health care workers (HCW) are low, and hospitalisation is often a missed opportunity for vaccination. We hypothesised that knowledge, attitude and practices of health care workers regarding vaccination impacts vaccine uptake in hospitals. The cardiac ward admits high-risk patients, many of whom are indicated for influenza vaccine, especially those caring for patients with acute MI.
    Aim: To understand the knowledge, attitudes, and practices of HCW in cardiology ward within a tertiary institution, on influenza vaccination.
    Methods: We used focus group discussions with HCW caring for AMI patients in an acute cardiology ward, to explore the knowledge, attitudes, and practices of HCW regarding influenza vaccination for patients under their care. Discussions were recorded, transcribed, and thematically analysed using NVivo software. In addition, participants completed a survey on their knowledge and attitudes towards the uptake of influenza vaccination.
    Results: A lack of awareness regarding the associations between influenza, vaccination and cardiovascular health was identified amongst HCW. Participants did not routinely discuss the benefits of influenza vaccination or recommend influenza vaccinations to patients under their care; this may be due to a combination of a lack of awareness, not seeing it as part of their job and workload issues. We also highlighted difficulties in access to vaccination, and concerns of adverse reactions to the vaccine.
    Conclusion: There is limited awareness among HCW of the role of influenza on cardiovascular health and the benefits of influenza vaccine in the prevention of cardiovascular events. Improved vaccination of at-risk patients in hospital may need active engagement of HCW. Improving the health literacy of HCW regarding the benefits of vaccination as a preventative strategy may result in better health care outcomes for cardiac patients.
    MeSH term(s) Adult ; Humans ; Influenza, Human/prevention & control ; Influenza Vaccines/therapeutic use ; Health Knowledge, Attitudes, Practice ; Vaccination ; Attitude of Health Personnel ; Health Personnel ; Surveys and Questionnaires ; Myocardial Infarction
    Chemical Substances Influenza Vaccines
    Language English
    Publishing date 2023-02-16
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.01.070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: EU-Wide Access to High-quality, Affordable Precision Diagnostics: An EHA Position Paper.

    Macintyre, Elizabeth / Gribben, John / Döhner, Konstanze

    HemaSphere

    2020  Volume 4, Issue 3, Page(s) e412

    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country United States
    Document type Editorial
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Knowledge, attitudes and practices of health care workers in a cardiology department on influenza vaccination

    Benedict Kpozehouen, Elizabeth / Arrudsivah, Bravien / Raina Macintyre, C

    Vaccine.

    2023  

    Abstract: Evidence has accrued that influenza vaccination may be effective in preventing myocardial infarction (MI). However, vaccination rates in both adults and health care workers (HCW) are low, and hospitalisation is often a missed opportunity for vaccination. ...

    Abstract Evidence has accrued that influenza vaccination may be effective in preventing myocardial infarction (MI). However, vaccination rates in both adults and health care workers (HCW) are low, and hospitalisation is often a missed opportunity for vaccination. We hypothesised that knowledge, attitude and practices of health care workers regarding vaccination impacts vaccine uptake in hospitals. The cardiac ward admits high-risk patients, many of whom are indicated for influenza vaccine, especially those caring for patients with acute MI. To understand the knowledge, attitudes, and practices of HCW in cardiology ward within a tertiary institution, on influenza vaccination. We used focus group discussions with HCW caring for AMI patients in an acute cardiology ward, to explore the knowledge, attitudes, and practices of HCW regarding influenza vaccination for patients under their care. Discussions were recorded, transcribed, and thematically analysed using NVivo software. In addition, participants completed a survey on their knowledge and attitudes towards the uptake of influenza vaccination. A lack of awareness regarding the associations between influenza, vaccination and cardiovascular health was identified amongst HCW. Participants did not routinely discuss the benefits of influenza vaccination or recommend influenza vaccinations to patients under their care; this may be due to a combination of a lack of awareness, not seeing it as part of their job and workload issues. We also highlighted difficulties in access to vaccination, and concerns of adverse reactions to the vaccine. There is limited awareness among HCW of the role of influenza on cardiovascular health and the benefits of influenza vaccine in the prevention of cardiovascular events. Improved vaccination of at-risk patients in hospital may need active engagement of HCW. Improving the health literacy of HCW regarding the benefits of vaccination as a preventative strategy may result in better health care outcomes for cardiac patients.
    Keywords computer software ; focus groups ; health education ; health services ; hospitals ; influenza ; influenza vaccination ; influenza vaccines ; myocardial infarction ; surveys
    Language English
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.01.070
    Database NAL-Catalogue (AGRICOLA)

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