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  1. Article ; Online: Microbial Dynamics in Sour–Sweet Wine Vinegar

    Alice Vilela

    Applied Sciences, Vol 13, Iss 7366, p

    Impacts on Chemical and Sensory Composition

    2023  Volume 7366

    Abstract: The most known and traditional vinegar is the one that is made from wine. For its production, the grape must undergo alcohol fermentation and the posterior oxidation of ethanol to acetic acid. Yeasts and acetic acid bacteria (AAB) carry out the ... ...

    Abstract The most known and traditional vinegar is the one that is made from wine. For its production, the grape must undergo alcohol fermentation and the posterior oxidation of ethanol to acetic acid. Yeasts and acetic acid bacteria (AAB) carry out the biochemical processes in sequence. The process of wine acetification can be achieved by slow traditional processes (the Orléans or French methods) or by a quick submerged industrial process. High-quality vinegar is usually produced by traditional methods using oak casks, once the wood allows the continuous aeration of the acetic bacteria culture. Sour–sweet vinegar presents a balance of both bitter/sour and sweet flavors. The sourness typically comes from acetic acid, while the sweetness can come from the type of fruit or the amount of sugar present at the end of vinegar production. In general, sour-sweet vinegar has a more complex and nuanced flavor profile compared to regular vinegar, which is often simply sour. One kind of vinegar produced by wine acetification where yeasts and bacteria co-exist and produce savory vinegar is traditional balsamic vinegar (TBV), from Italy. In Spain, fortified sherry wine has also been used for vinegar production. In Portugal, some wine companies have produced port wine vinegar since 2018. These three distinctive vinegar products have in common the sweetness that can be found, well balanced with the acetic acid sourness. In this review, we analyze the sour-sweat wine vinegar process, bearing in mind the possible interactions between yeasts and AAB that occur during vinegar production and considering the symbiotic or competitive features of a diverse microbiota.
    Keywords traditional balsamic vinegar ; Orléans method ; sherry vinegar ; port wine vinegar ; yeasts ; acetic acid bacteria ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 660
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: EXISTEM FATORES PREDITIVOS DE PIOR EVOLUÇÃO EM PACIENTES PEDIÁTRICOS COM COVID-19?

    Vilela, T.S. / Braga, J.A.P. / Angel, A. / Loggetto, S.R.

    Hematology, Transfusion and Cell Therapy

    2020  Volume 42, Page(s) 310–311

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2531-1379
    DOI 10.1016/j.htct.2020.10.516
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Search for Scalar Leptoquarks Produced via τ-Lepton-Quark Scattering in pp Collisions at sqrt[s]=13  TeV.

    Hayrapetyan, A / Tumasyan, A / Adam, W / Andrejkovic, J W / Bergauer, T / Chatterjee, S / Damanakis, K / Dragicevic, M / Escalante Del Valle, A / Hussain, P S / Jeitler, M / Krammer, N / Liko, D / Mikulec, I / Schieck, J / Schöfbeck, R / Schwarz, D / Sonawane, M / Templ, S /
    Waltenberger, W / Wulz, C-E / Darwish, M R / Janssen, T / Van Mechelen, P / Bols, E S / D'Hondt, J / Dansana, S / De Moor, A / Delcourt, M / El Faham, H / Lowette, S / Makarenko, I / Müller, D / Sahasransu, A R / Tavernier, S / Tytgat, M / Van Putte, S / Vannerom, D / Clerbaux, B / De Lentdecker, G / Favart, L / Hohov, D / Jaramillo, J / Khalilzadeh, A / Lee, K / Mahdavikhorrami, M / Malara, A / Paredes, S / Pétré, L / Postiau, N / Thomas, L / Vanden Bemden, M / Vander Velde, C / Vanlaer, P / De Coen, M / Dobur, D / Hong, Y / Knolle, J / Lambrecht, L / Mestdach, G / Rendón, C / Samalan, A / Skovpen, K / Van Den Bossche, N / Wezenbeek, L / Benecke, A / Bruno, G / Caputo, C / Delaere, C / Donertas, I S / Giammanco, A / Jaffel, K / Jain, Sa / Lemaitre, V / Lidrych, J / Mastrapasqua, P / Mondal, K / Tran, T T / Wertz, S / Alves, G A / Coelho, E / Hensel, C / Menezes De Oliveira, T / Moraes, A / Rebello Teles, P / Soeiro, M / Aldá Júnior, W L / Alves Gallo Pereira, M / Barroso Ferreira 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Sun, X / Wang, D / Yang, H / Zhang, L / Zhou, C / You, Z / Lu, N / Gao, X / Leggat, D / Okawa, H / Zhang, Y / Lin, Z / Lu, C / Xiao, M / Avila, C / Barbosa Trujillo, D A / Cabrera, A / Florez, C / Fraga, J / Reyes Vega, J A / Mejia Guisao, J / Ramirez, F / Rodriguez, M / Ruiz Alvarez, J D / Giljanovic, D / Godinovic, N / Lelas, D / Sculac, A / Kovac, M / Sculac, T / Bargassa, P / Brigljevic, V / Chitroda, B K / Ferencek, D / Mishra, S / Starodumov, A / Susa, T / Attikis, A / Christoforou, K / Konstantinou, S / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Rykaczewski, H / Saka, H / Stepennov, A / Finger, M / Kveton, A / Ayala, E / Carrera Jarrin, E / Assran, Y / Elgammal, S / Abdullah Al-Mashad, M / Mahmoud, M A / Dewanjee, R K / Ehataht, K / Kadastik, M / Lange, T / Nandan, S / Nielsen, C / Pata, J / Raidal, M / Tani, L / Veelken, C / Kirschenmann, H / Osterberg, K / Voutilainen, M / Bharthuar, S / Brücken, E / Garcia, F / Havukainen, J / Kallonen, K T S / Kim, M S / Kinnunen, R / Lampén, T / Lassila-Perini, K / Lehti, S / Lindén, T / Lotti, M / Martikainen, L / Myllymäki, M / Rantanen, M M / Siikonen, H / Tuominen, E / Tuominiemi, J / Luukka, P / Petrow, H / Tuuva, T / Besancon, M / Couderc, F / Dejardin, M / Denegri, D / Faure, J L / Ferri, F / Ganjour, S / Gras, P / Hamel de Monchenault, G / Lohezic, V / Malcles, J / Rander, J / Rosowsky, A / Sahin, M Ö / Savoy-Navarro, A / Simkina, P / Titov, M / Baldenegro Barrera, C / Beaudette, F / Buchot Perraguin, A / Busson, P / Cappati, A / Charlot, C / Damas, F / Davignon, O / De Wit, A / Falmagne, G / Fontana Santos Alves, B A / Ghosh, S / Gilbert, A / Granier de Cassagnac, R / Hakimi, A / Harikrishnan, B / Kalipoliti, L / Liu, G / Motta, J / Nguyen, M / Ochando, C / Portales, L / Salerno, R / Sarkar, U / Sauvan, J B / Sirois, Y / Tarabini, A / Vernazza, E / Zabi, A / Zghiche, A / Agram, J-L / Andrea, J / Apparu, D / Bloch, D / Brom, J-M / Chabert, E C / Collard, C / Falke, S / Goerlach, U / Grimault, C / Haeberle, R / Le Bihan, A-C / Sessini, M A / Van Hove, P / Beauceron, S / Blancon, B / Boudoul, G / Chanon, N / Choi, J / Contardo, D / Depasse, P / Dozen, C / El Mamouni, H / Fay, J / Gascon, S / Gouzevitch, M / Greenberg, C / Grenier, G / Ille, B / Laktineh, I B / Lethuillier, M / Mirabito, L / Perries, S / Purohit, A / Vander Donckt, M / Verdier, P / Xiao, J / Khvedelidze, A / Lomidze, I / Tsamalaidze, Z / Botta, V / Feld, L / Klein, K / Lipinski, M / Meuser, D / Pauls, A / Röwert, N / Teroerde, M / Diekmann, S / Dodonova, A / Eich, N / Eliseev, D / Engelke, F / Erdmann, M / Fackeldey, P / Fischer, B / Hebbeker, T / Hoepfner, K / Ivone, F / Jung, A / Lee, M Y / Mastrolorenzo, L / Merschmeyer, M / Meyer, A / Mukherjee, S / Noll, D / Novak, A / Nowotny, F / Pozdnyakov, A / Rath, Y / Redjeb, W / Rehm, F / Reithler, H / Sarkisovi, V / Schmidt, A / Schuler, S C / Sharma, A / Stein, A / Torres Da Silva De Araujo, F / Vigilante, L / Wiedenbeck, S / Zaleski, S / Dziwok, C / Flügge, G / Haj Ahmad, W / Kress, T / Nowack, A / Pooth, O / Stahl, A / Ziemons, T / Zotz, A / Aarup Petersen, H / Aldaya Martin, M / Alimena, J / Amoroso, S / An, Y / Baxter, S / Bayatmakou, M / Becerril Gonzalez, H / Behnke, O / Belvedere, A / Bhattacharya, S / Blekman, F / Borras, K / Brunner, D / Campbell, A / Cardini, A / Cheng, C / Colombina, F / Consuegra Rodríguez, S / Correia Silva, G / De Silva, M / Eckerlin, G / Eckstein, D / Estevez Banos, L I / Filatov, O / Gallo, E / Geiser, A / Giraldi, A / Greau, G / Guglielmi, V / Guthoff, M / Hinzmann, A / Jafari, A / Jeppe, L / Jomhari, N Z / Kaech, B / Kasemann, M / Kaveh, H / Kleinwort, C / Kogler, R / Komm, M / Krücker, D / Lange, W / Leyva Pernia, D / Lipka, K / Lohmann, W / Mankel, R / Melzer-Pellmann, I-A / Mendizabal Morentin, M / Metwally, J / Meyer, A B / Milella, G / Mussgiller, A / Nürnberg, A / Otarid, Y / Pérez Adán, D / Ranken, E / Raspereza, A / Ribeiro Lopes, B / Rübenach, J / Saggio, A / Scham, M / Schnake, S / Schütze, P / Schwanenberger, C / Selivanova, D / Shchedrolosiev, M / Sosa Ricardo, R E / Sreelatha Pramod, L P / Stafford, D / Vazzoler, F / Ventura Barroso, A / Walsh, R / Wang, Q / Wen, Y / Wichmann, K / Wiens, L / Wissing, C / Wuchterl, S / Yang, Y / Zimermmane Castro Santos, A / Albrecht, A / Albrecht, S / Antonello, M / Bein, S / Benato, L / Bonanomi, M / Connor, P / Eich, M / El Morabit, K / Fischer, Y / Fröhlich, A / Garbers, C / Garutti, E / Grohsjean, A / Hajheidari, M / Haller, J / Jabusch, H R / Kasieczka, G / Keicher, P / Klanner, R / Korcari, W / Kramer, T / Kutzner, V / Labe, F / Lange, J / Lobanov, A / Matthies, C / Mehta, A / Moureaux, L / Mrowietz, M / Nigamova, A / Nissan, Y / Paasch, A / Pena Rodriguez, K J / Quadfasel, T / Raciti, B / Rieger, M / Savoiu, D / Schindler, J / Schleper, P / Schröder, M / Schwandt, J / Sommerhalder, M / Stadie, H / Steinbrück, G / Tews, A / Wolf, M / Brommer, S / Burkart, M / Butz, E / Chwalek, T / Dierlamm, A / Droll, A / Faltermann, N / Giffels, M / Gottmann, A / Hartmann, F / Hofsaess, R / Horzela, M / Husemann, U / Klute, M / Koppenhöfer, R / Link, M / Lintuluoto, A / Maier, S / Mitra, S / Mormile, M / Müller, Th / Neukum, M / Oh, M / Quast, G / Rabbertz, K / Regnery, B / Shadskiy, N / Shvetsov, I / Simonis, H J / Trevisani, N / Ulrich, R / van der Linden, J / Von Cube, R F / Wassmer, M / Wieland, S / Wittig, F / Wolf, R / Wunsch, S / Zuo, X / Anagnostou, G / Assiouras, P / Daskalakis, G / Kyriakis, A / Papadopoulos, A / Stakia, A / Kontaxakis, P / Melachroinos, G / Panagiotou, A / Papavergou, I / Paraskevas, I / Saoulidou, N / Theofilatos, K / Tziaferi, E / Vellidis, K / Zisopoulos, I / Bakas, G / Chatzistavrou, T / Karapostoli, G / Kousouris, K / Papakrivopoulos, I / Siamarkou, E / Tsipolitis, G / Zacharopoulou, A / Adamidis, K / Bestintzanos, I / Evangelou, I / Foudas, C / Gianneios, P / Kamtsikis, C / Katsoulis, P / Kokkas, P / Kosmoglou Kioseoglou, P G / Manthos, N / Papadopoulos, I / Strologas, J / Csanád, M / Farkas, K 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    Physical review letters

    2024  Volume 132, Issue 6, Page(s) 61801

    Abstract: The first search for scalar leptoquarks produced in τ-lepton-quark collisions is presented. It is based on a set of proton-proton collision data recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV corresponding to an integrated ...

    Abstract The first search for scalar leptoquarks produced in τ-lepton-quark collisions is presented. It is based on a set of proton-proton collision data recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV corresponding to an integrated luminosity of 138  fb^{-1}. The reconstructed final state consists of a jet, significant missing transverse momentum, and a τ lepton reconstructed through its hadronic or leptonic decays. Limits are set on the product of the leptoquark production cross section and branching fraction and interpreted as exclusions in the plane of the leptoquark mass and the leptoquark-τ-quark coupling strength.
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.061801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: New Structures in the J/ψJ/ψ Mass Spectrum in Proton-Proton Collisions at sqrt[s]=13  TeV.

    Hayrapetyan, A / Tumasyan, A / Adam, W / Andrejkovic, J W / Bergauer, T / Chatterjee, S / Damanakis, K / Dragicevic, M / Escalante Del Valle, A / Hussain, P S / Jeitler, M / Krammer, N / Liko, D / Mikulec, I / Schieck, J / Schöfbeck, R / Schwarz, D / Sonawane, M / Templ, S /
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    Physical review letters

    2024  Volume 132, Issue 11, Page(s) 111901

    Abstract: ... in proton-proton collisions at sqrt[s]=13  TeV from data collected by the CMS experiment, corresponding ...

    Abstract A search is reported for near-threshold structures in the J/ψJ/ψ invariant mass spectrum produced in proton-proton collisions at sqrt[s]=13  TeV from data collected by the CMS experiment, corresponding to an integrated luminosity of 135  fb^{-1}. Three structures are found, and a model with quantum interference among these structures provides a good description of the data. A new structure is observed with a local significance above 5 standard deviations at a mass of 6638_{-38}^{+43}(stat)_{-31}^{+16}(syst)  MeV. Another structure with even higher significance is found at a mass of 6847_{-28}^{+44}(stat)_{-20}^{+48}(syst)  MeV, which is consistent with the X(6900) resonance reported by the LHCb experiment and confirmed by the ATLAS experiment. Evidence for another new structure, with a local significance of 4.7 standard deviations, is found at a mass of 7134_{-25}^{+48}(stat)_{-15}^{+41}(syst)  MeV. Results are also reported for a model without interference, which does not fit the data as well and shows mass shifts up to 150 MeV relative to the model with interference.
    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.111901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Observation of WWγ Production and Search for Hγ Production in Proton-Proton Collisions at sqrt[s]=13  TeV.

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Montalvo, R / Nash, K / Routray, H / Salur, S / Schnetzer, S / Somalwar, S / Stone, R / Thayil, S A / Thomas, S / Vora, J / Wang, H / Acharya, H / Ally, D / Delannoy, A G / Fiorendi, S / Holmes, T / Karunarathna, N / Lee, L / Nibigira, E / Spanier, S / Aebi, D / Ahmad, M / Bouhali, O / Dalchenko, M / Eusebi, R / Gilmore, J / Huang, T / Kamon, T / Luo, S / Malhotra, S / Mueller, R / Overton, D / Rathjens, D / Safonov, A / Akchurin, N / Damgov, J / Hegde, V / Hussain, A / Kazhykarim, Y / Lamichhane, K / Mankel, A / Mengke, T / Muthumuni, S / Peltola, T / Volobouev, I / Whitbeck, A / Appelt, E / Greene, S / Gurrola, A / Johns, W / Kunnawalkam Elayavalli, R / Melo, A / Romeo, F / Sheldon, P / Tuo, S / Velkovska, J / Viinikainen, J / Cardwell, B / Cox, B / Hakala, J / Hirosky, R / Ledovskoy, A / Li, A / Neu, C / Perez Lara, C E / Karchin, P E / Aravind, A / Black, K / Bose, T / Dasu, S / De Bruyn, I / Everaerts, P / Galloni, C / He, H / Herndon, M / Herve, A / Koraka, C K / Lanaro, A / 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    Physical review letters

    2024  Volume 132, Issue 12, Page(s) 121901

    Abstract: The observation of WWγ production in proton-proton collisions at a center-of-mass energy of 13 TeV with an integrated luminosity of 138  fb^{-1} is presented. The observed (expected) significance is 5.6 (5.1) standard deviations. Events are selected by ... ...

    Abstract The observation of WWγ production in proton-proton collisions at a center-of-mass energy of 13 TeV with an integrated luminosity of 138  fb^{-1} is presented. The observed (expected) significance is 5.6 (5.1) standard deviations. Events are selected by requiring exactly two leptons (one electron and one muon) of opposite charge, moderate missing transverse momentum, and a photon. The measured fiducial cross section for WWγ is 5.9±0.8(stat)±0.8(syst)±0.7(modeling)  fb, in agreement with the next-to-leading order quantum chromodynamics prediction. The analysis is extended with a search for the associated production of the Higgs boson and a photon, which is generated by a coupling of the Higgs boson to light quarks. The result is used to constrain the Higgs boson couplings to light quarks.
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.121901
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  6. Article ; Online: T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1.

    de Sena Rodrigues Júnior, Roberto / Antonia Nunes Gomes, Jéssica / Alberto da Silva Dias, George / Fujihara, Satomi / Toshimitsu Yoshikawa, Gilberto / Vilela Lopes Koyama, Roberta / Catarina Medeiros Sousa, Rita / Antonio Simões Quaresma, Juarez / Thais Fuzii, Hellen

    Immunobiology

    2023  Volume 228, Issue 6, Page(s) 152740

    Abstract: Human T-lymphotropic virus 1 (HTLV-1) affects 5-10 million individuals worldwide. Most ... myelopathy/tropical spastic paraparesis (HAM/TSP), while 2%-4% develop adult T-cell leukemia/lymphoma (ATLL ... Understanding the immune response inherent in this infection is extremely important. The role of T helper type 1 ...

    Abstract Human T-lymphotropic virus 1 (HTLV-1) affects 5-10 million individuals worldwide. Most of those infected with this virus remain asymptomatic; however, 0.25%-4% of individuals develop HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), while 2%-4% develop adult T-cell leukemia/lymphoma (ATLL). Understanding the immune response inherent in this infection is extremely important. The role of T helper type 1 (Th1) and Th2 cells in HTLV-1 infection is well known; however, exploring the different subtypes of immune responses is also necessary. The role of Th9 cells in HTLV-1 infection and the mechanisms involved in their interference in the pathophysiological process of HAM/TSP is poorly understood. This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb reflexes, Hoffman's sign, Babinski reflex, and clonus reflex). For Th9 cell analysis, peripheral blood samples were collected from HTLV-1-infected patients; then, the lymphomononuclear cells were separated followed by the isolation of messenger ribonucleic acid (mRNA). Complementary deoxyribonucleic acid (cDNA) synthesis each sample was carried out. The gene expression levels of PU.1, IRF-4, and IL-9 as well as those of constitutive genes (glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and β-actin) were quantified by real-time polymerase chain reaction (qPCR). This study included 81 HTLV-1-infected patients, of whom 47 were asymptomatic, 13 were mono/oligosymptomatic (MOS), and 21 developed HAM/TSP. IL-9 was the least expressed gene among the three studied groups. The MOS group showed the lowest expression levels of PU.1, IRF-4, and IL-9. HAM/TSP patients showed lower IL-9 protein quantification. Negative correlations were found between IL and 9 and EDSS in MOS patients and between PU.1, EDSS, IRF-4, and EDSS in the HAM/TSP group. An association was found between IL and 9 and Babinski reflex in the HAM/TSP group, suggesting that this gene was more highly expressed in patients who did not have this pathological sign. Th9 cells may interfere with the neurological progression of HAM/TSP and act as a protective factor.
    MeSH term(s) Adult ; Humans ; Human T-lymphotropic virus 1/genetics ; Interleukin-9 ; Cross-Sectional Studies ; Paraparesis, Tropical Spastic/genetics ; HTLV-I Infections/genetics
    Chemical Substances Interleukin-9
    Language English
    Publishing date 2023-08-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 563292-4
    ISSN 1878-3279 ; 0171-2985
    ISSN (online) 1878-3279
    ISSN 0171-2985
    DOI 10.1016/j.imbio.2023.152740
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  7. Article ; Online: Search for Inelastic Dark Matter in Events with Two Displaced Muons and Missing Transverse Momentum in Proton-Proton Collisions at sqrt[s]=13  TeV.

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Slabospitskii, S / Smirnov, V / Snigirev, A / Sosnov, D / Sulimov, V / Tcherniaev, E / Terkulov, A / Teryaev, O / Tlisova, I / Toropin, A / Uvarov, L / Uzunian, A / Vorobyev, A / Voytishin, N / Yuldashev, B S / Zarubin, A / Zhizhin, I / Zhokin, A

    Physical review letters

    2024  Volume 132, Issue 4, Page(s) 41802

    Abstract: A search for dark matter in events with a displaced nonresonant muon pair and missing transverse momentum is presented. The analysis is performed using an integrated luminosity of 138  fb^{-1} of proton-proton (pp) collision data at a center-of-mass ... ...

    Abstract A search for dark matter in events with a displaced nonresonant muon pair and missing transverse momentum is presented. The analysis is performed using an integrated luminosity of 138  fb^{-1} of proton-proton (pp) collision data at a center-of-mass energy of 13 TeV produced by the LHC in 2016-2018. No significant excess over the predicted backgrounds is observed. Upper limits are set on the product of the inelastic dark matter production cross section σ(pp→A^{'}→χ_{1}χ_{2}) and the decay branching fraction B(χ_{2}→χ_{1}μ^{+}μ^{-}), where A^{'} is a dark photon and χ_{1} and χ_{2} are states in the dark sector with near mass degeneracy. This is the first dedicated collider search for inelastic dark matter.
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.041802
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  8. Article ; Online: EXISTEM FATORES PREDITIVOS DE PIOR EVOLUÇÃO EM PACIENTES PEDIÁTRICOS COM COVID-19?

    T.S. Vilela / J.A.P. Braga / A. Angel / S.R. Loggetto

    Hematology, Transfusion and Cell Therapy, Vol 42, Iss , Pp 310-

    2020  Volume 311

    Keywords Diseases of the blood and blood-forming organs ; RC633-647.5 ; covid19
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
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  9. Article ; Online: Clinical Correlates of the PET-based Braak Staging Framework in Alzheimer's Disease.

    Macedo, A C / Durço, D F P A / Tissot, C / Therriault, J / Vilela de Faria, A O / Aumont, É / Servaes, S / Rahmouni, N / Fernandez-Arias, J / Wang, Y-T / Lussier, F Z / Bieger, A / Zimmer, E R / Pascoal, T A / Gauthier, S / Rosa-Neto, P

    The journal of prevention of Alzheimer's disease

    2024  Volume 11, Issue 2, Page(s) 414–421

    Abstract: In vivo Alzheimer's disease diagnosis and staging is traditionally based on clinical features ... However, the agreement between clinical and pathological Alzheimer's disease diagnosis, whose diagnosis assessment ... of Alzheimer's disease from both biological and clinical perspectives. Recent advances in radiochemistry made it possible ...

    Abstract In vivo Alzheimer's disease diagnosis and staging is traditionally based on clinical features. However, the agreement between clinical and pathological Alzheimer's disease diagnosis, whose diagnosis assessment includes amyloid and Braak histopathological tau staging, is not completely convergent. The development of positron emission tomography (PET) tracers targeting neurofibrillary tangles offers prospects for advancing the staging of Alzheimer's disease from both biological and clinical perspectives. Recent advances in radiochemistry made it possible to apply the postmortem Braak staging framework to tau-PET images obtained in vivo. Here, our aim is to provide a narrative review of the current literature on the relationship between Alzheimer's disease clinical features and the PET-based Braak staging framework. Overall, the available studies support the stepwise increase in disease severity following the advance of PET-based Braak stages, with later stages being associated with worse cognitive and clinical symptoms. In line with this, there is a trend for unimpaired cognition, mild cognitive impairment, and Alzheimer's disease dementia to be compatible with early, intermediate, and late patterns of tau deposition based on PET-based Braak stages. Moreover, neuropsychiatric symptom severity seems to be linked to the extent of tau-PET signal across Braak areas. In sum, this framework seems to correspond well with the clinical progression of Alzheimer's disease, which is an indication of its potential utility in research and clinical practice, especially for detecting preclinical tau levels in individuals without symptoms. However, further research is needed to improve the generalizability of these findings and to better understand the applications of this staging framework.
    MeSH term(s) Humans ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/pathology ; tau Proteins ; Neurofibrillary Tangles/pathology ; Positron-Emission Tomography/methods ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/pathology
    Chemical Substances tau Proteins
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Review ; Journal Article
    ZDB-ID 2782183-3
    ISSN 2426-0266 ; 2274-5807
    ISSN (online) 2426-0266
    ISSN 2274-5807
    DOI 10.14283/jpad.2024.15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Advanced Nanocellulose-Based Materials: Production, Properties, and Applications.

    Freire, Carmen S R / Vilela, Carla

    Nanomaterials (Basel, Switzerland)

    2022  Volume 12, Issue 3

    Abstract: Natural polymers, such as polysaccharides and proteins, are being extensively utilized as substrates to create advanced materials [ ... ]. ...

    Abstract Natural polymers, such as polysaccharides and proteins, are being extensively utilized as substrates to create advanced materials [...].
    Language English
    Publishing date 2022-01-27
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano12030431
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