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Article: COLQ

Yin, Yatao / Cao, Jing / Fan, Yuanteng / Xu, Yan

2023 Volume 9, Issue 9, Page(s) e19980

Abstract: Congenital myasthenia syndromes (CMS) are a heterogeneous group of hereditary disorders of the neuromuscular junction. The symptoms include fatigue, muscle weakness, ptosis, mastication or swallowing problem, respiratory distress. We present a 42-year- ... ...

Abstract	Congenital myasthenia syndromes (CMS) are a heterogeneous group of hereditary disorders of the neuromuscular junction. The symptoms include fatigue, muscle weakness, ptosis, mastication or swallowing problem, respiratory distress. We present a 42-year-old male patient who was admitted with complaints of paroxysmal limb weakness for 25 years and got repeated apnea crisis due to using AchE inhibitors. We considered this patient to be
Language	English
Publishing date	2023-09-12
Publishing country	England
Document type	Case Reports
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e19980
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Article ; Online: Effect of Transcranial Direct Current Stimulation on Patients With Disorders of Consciousness: A Systematic Review and Meta-analysis.

Fan, Wei / Fan, Yuanteng / Liao, Zhenjun / Yin, Yatao

American journal of physical medicine & rehabilitation

2023 Volume 102, Issue 12, Page(s) 1102–1110

Abstract: Objectives: The aims of this study are to evaluate the efficacy of transcranial direct current stimulation for improving disorders of consciousness and to compare efficacy of the different etiologies of disorders of consciousness.: Design: Randomized ...

Abstract	Objectives: The aims of this study are to evaluate the efficacy of transcranial direct current stimulation for improving disorders of consciousness and to compare efficacy of the different etiologies of disorders of consciousness. Design: Randomized controlled trials or crossover trials examining effects of transcranial direct current stimulation in patients with disorders of consciousness were searched in PubMed, Embase, Cochrane Library, and Web of Science. The sample characteristics, etiology, transcranial direct current stimulation treatment characteristics, and outcomes were extracted. Meta-analysis was performed using the RevMan software. Results: We included nine trials providing data with 331 participants and found that transcranial direct current stimulation improved the Coma Recovery Scale-Revised score of disorders of consciousness patients. We found a significant improvement of Coma Recovery Scale-Revised score in the minimally conscious state group (weighted mean difference = 0.77, 95% confidence interval = 0.30-1.23, P = 0.001), but not in the vegetative state or unresponsive wakefulness syndrome group. The effects of transcranial direct current stimulation are related to etiology, as the Coma Recovery Scale-Revised score was improved in the traumatic brain injury group (weighted mean difference = 1.18, 95% confidence interval = 0.60-1.75, P < 0.001), but not in vascular accident and anoxia groups. Conclusions: This meta-analysis revealed the evidence for positive effects of transcranial direct current stimulation on disorders of consciousness without adverse effects observed in minimally conscious state patients. In particular, transcranial direct current stimulation may be an effective treatment in rehabilitating cognitive functions in people with traumatic brain injury.
MeSH term(s)	Humans ; Transcranial Direct Current Stimulation ; Persistent Vegetative State/therapy ; Coma/therapy ; Consciousness Disorders/therapy ; Brain Injuries, Traumatic
Language	English
Publishing date	2023-05-16
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	219390-5
ISSN	1537-7385 ; 0002-9491 ; 0894-9115
ISSN (online)	1537-7385
ISSN	0002-9491 ; 0894-9115
DOI	10.1097/PHM.0000000000002290
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Article ; Online: Rational Design of MXene Hollow Fiber Membranes for Gas Separations.

Zhang, Yiming / Sheng, Kai / Wang, Zheng / Wu, Wenjia / Yin, Ben Hang / Zhu, Junyong / Zhang, Yatao

Nano letters

2023 Volume 23, Issue 7, Page(s) 2710–2718

Abstract: One scalable and facile dip-coating approach was utilized to construct a thin ... ...

Abstract	One scalable and facile dip-coating approach was utilized to construct a thin CO
Language	English
Publishing date	2023-03-16
Publishing country	United States
Document type	Journal Article
ISSN	1530-6992
ISSN (online)	1530-6992
DOI	10.1021/acs.nanolett.3c00004
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Article: Anisotropic scattering characteristics of nanoparticles in different morphologies: improving the temperature uniformity of tumors during thermal therapy using forward scattering.

Chen, Qin / Ren, Yatao / Yin, Yanmei / Qi, Hong

Biomedical optics express

2021 Volume 12, Issue 2, Page(s) 893–906

Abstract: Precise control of the thermal damage area is the key issue during thermal therapy, which can be achieved by manipulating the light propagation in biological tissue. In the present work, a method is proposed to increase the uniformity of the specific ... ...

Abstract	Precise control of the thermal damage area is the key issue during thermal therapy, which can be achieved by manipulating the light propagation in biological tissue. In the present work, a method is proposed to increase the uniformity of the specific absorption rate (SAR) distribution in tumors during laser-induced thermal therapy, which is proved to be effective in reducing the thermal damage of healthy tissue. In addition, a better way of manipulating light propagation in biological tissue is explored. It is found that the anisotropic scattering characteristics of nanoparticles are strongly dependent on their shapes, sizes, orientations, and incident wavelengths, which will strongly affect the light propagation in nanoparticle embedded biological tissue. Therefore, to obtain a better outcome from photothermal therapy, the scattering properties of nanoparticles are very important factors that need to be taken into consideration, along with the absorption efficiency. Further investigation finds that nanoparticles that predominantly scatter to the forward direction are favorable in obtaining a larger penetration depth of light, which will improve the uniformity of SAR and temperature distributions. This paper is meaningful for the application of nanoparticle-assisted laser-induced thermal therapy.
Language	English
Publishing date	2021-01-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2572216-5
ISSN	2156-7085
ISSN	2156-7085
DOI	10.1364/BOE.415666
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Article ; Online: Perpendicular Alignment of Covalent Organic Framework (COF) Pore Channels by Solvent Vapor Annealing.

Yin, Congcong / Liu, Ming / Zhang, Zhe / Wei, Mingjie / Shi, Xiansong / Zhang, Yatao / Wang, Jingtao / Wang, Yong

Journal of the American Chemical Society

2023 Volume 145, Issue 20, Page(s) 11431–11439

Abstract: Covalent organic frameworks (COFs) have showcased great potential in diverse applications such as separation and catalysis, where mass transfer confined in their pore channels plays a significant role. However, anisotropic orientation usually occurs in ... ...

Abstract	Covalent organic frameworks (COFs) have showcased great potential in diverse applications such as separation and catalysis, where mass transfer confined in their pore channels plays a significant role. However, anisotropic orientation usually occurs in polycrystalline COFs, and perpendicular alignment of COF pore channels is ultimately desired to maximize their performance. Herein, we demonstrate a strategy, solvent vapor annealing, to reorient COF pore channels from anisotropic orientation to perpendicular alignment. COF thin films are first synthesized to have flexible N-H bonds in their skeletons, thus having structural mobility to enable molecular rearrangement. A solvent with low relative permittivity and a conjugated structure is then identified to have a strong affinity toward the COFs, allowing its vapor to easily penetrate into the COF interlayers. The solvent vapor weakens the π-π interaction and consequently allows the COF monolayers to dissociate. The COF monolayers undergo a reorientation process that converts from random stacking into the face-on stacking fashion, in which the through COF pores are perpendicularly aligned. The aligned COF film exhibits high separation precision toward ions featuring a size difference down to 2 Å, which is 8 times higher than that of the anisotropically oriented counterpart. This work opens up an avenue for COF orientation regulation by solvent vapor annealing and reveals the essential role of the perpendicular alignment of COF pore channels to enable precision separations.
Language	English
Publishing date	2023-05-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c03198
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Article ; Online: Enhanced performance of thin-film nanocomposite membranes achieved by hierarchical zeolites for nanofiltration

Wang, Danhua / Tian, Miaomiao / Han, Shuangqiao / Ding, Kai / Yin, Liya / Zhu, Junyong / Zhang, Yatao / Han, Li

Journal of Membrane Science. 2023 Apr., v. 671 p.121405-

2023

Abstract: Nanosized zeolite molecular sieves are increasingly explored for developing high-performance nanocomposite membranes, mainly because of their ordered pore structures and remarkable thermal stability. In this study, hierarchical nanosized aluminophosphate ...

Abstract	Nanosized zeolite molecular sieves are increasingly explored for developing high-performance nanocomposite membranes, mainly because of their ordered pore structures and remarkable thermal stability. In this study, hierarchical nanosized aluminophosphate molecular sieves [AlPO-5 (AFI)] were synthesized as functional fillers to construct thin-film nanocomposite (TFN) membranes. Nanosized AlPO-5 was effectively positioned onto porous polysulfone supports via a filtration-assisted method, followed by in situ interfacial polymerization to construct a polyamide layer atop the modified supports. The synthesized nanosized AlPO-5 crystals have both intrinsic micropores and abundant intracrystalline mesopores. SEM and AFM analyses reveal that the introduction of AlPO-5 not only enhanced the surface roughness of TFN membranes with valley-shaped surface but also substantially decreased the thickness of a polyamide layer compared to nodular-shaped TFC membranes. These differences are mainly ascribed to retarded piperazine diffusion and positioned AlPO-5 nanoaggregates. The role of AlPO-5 loading in overall separation performance of TFN membranes was studied. The best-performing TFN membranes showed the highest water permeability of 23.2 L m⁻² h⁻¹ bar⁻¹, nearly twice that of unmodified TFC membranes, while maintaining a high salt rejection of 97.5%. The thickened and roughened polyamide layer with reduced transport resistance as well as intrinsic abundant mesopores of AlPO-5 fillers mainly contribute to the enhanced water transport. This study highlights the usage of hierarchical zeolite molecular sieves to fabricate high-permeable polyamide membranes for elevated nanofiltration performance.
Keywords	micropores ; nanocomposites ; nanofiltration ; nanomaterials ; permeability ; piperazine ; polyamides ; polymerization ; surface roughness ; thermal stability ; zeolites ; Interfacial polymerization ; AlPO-5 (AFI) zeolite ; Thin-film nanocomposite
Language	English
Dates of publication	2023-04
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	194516-6
ISSN	0376-7388
ISSN	0376-7388
DOI	10.1016/j.memsci.2023.121405
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Article ; Online: A Parametric Investigation of Corneal Laser Surgery Based on the Multilayer Dynamic Photothermal Model.

Zhang, Juqi / Ren, Yatao / Yin, Yanmei / Qi, Hong

Journal of biomechanical engineering

2020 Volume 143, Issue 4

Abstract: Corneal laser surgery is a widely used method for the treatment of ocular myopia, hyperopia, and astigmatism. Although it is a well-established technique, the photothermal properties of the cornea are often overlooked, causing unexpected changes in ... ...

Abstract	Corneal laser surgery is a widely used method for the treatment of ocular myopia, hyperopia, and astigmatism. Although it is a well-established technique, the photothermal properties of the cornea are often overlooked, causing unexpected changes in temperature during laser irradiation. Therefore, there is a need for further investigation of the temperature response of the cornea under laser irradiation. In the present work, a photothermal corneal numerical model is presented, assuming the stratification of the cornea with laser ablation in an uncoagulated layer, a coagulated layer, a dehydrating layer, a dried layer, and a carbonized layer. The modified Pennes' bioheat transfer equation and Lambert-Beer's law are applied to simulate heat transfer in the corneal tissue during laser irradiation. And the corneal dynamic photothermal parameters are considered in the proposed model. The central surface temperature, the boundary and thickness of each layer, and the thermal damage during laser irradiation are investigated. From the model, it was found that in the steady-state process, the thickness of the coagulated layer was 2.6, 14.4, and 52.4 times larger than that of the dehydrating layer, the dried layer, and the carbonized layer, respectively. The thickness of the corneal thermal damage gradually increased, and reached a peak of 0.196 mm at about 18.2 ms. Subsequently, it sharply decreased by 0.01 mm before stabilizing. On this basis, the influence of laser intensity is investigated. The parametric investigation and analysis presented provide a theoretical basis for corneal laser surgery, which can be used to improve our understanding of laser-tissue surgery.
MeSH term(s)	Myopia
Language	English
Publishing date	2020-11-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	243094-0
ISSN	1528-8951 ; 0148-0731
ISSN (online)	1528-8951
ISSN	0148-0731
DOI	10.1115/1.4049156
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Article ; Online: Functional roles of enhancer of zeste homolog 2 in gliomas.

Yin, Yatao / Qiu, Shuwei / Peng, Ying

Gene

2016 Volume 576, Issue 1 Pt 2, Page(s) 189–194

Abstract: Gliomas are the most common and lethal type of primary malignant brain tumor. Due to the infiltrative nature and high resistance to standard first line treatment with combinations of radiation and chemotherapy, the prognosis of patient is very poor. ... ...

Abstract	Gliomas are the most common and lethal type of primary malignant brain tumor. Due to the infiltrative nature and high resistance to standard first line treatment with combinations of radiation and chemotherapy, the prognosis of patient is very poor. Recently, accumulated evidence suggests that enhancer of zeste homolog 2 (EZH2) serves as an oncogene and is involved in multiple glioma cell processes, including cell cycle, invasion, glioma stem cell maintenance, drug and radiotherapy resistance and so on. In this review, we will focus on updating current knowledge of EZH2 in gliomas. Moreover, the regulation of EZH2 by microRNAs and long non-coding RNAs and the therapeutic strategies targeting EZH2 for gliomas will also be discussed.
MeSH term(s)	Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Brain Neoplasms/pathology ; Brain Neoplasms/therapy ; Cell Cycle/genetics ; Central Nervous System Neoplasms/genetics ; Central Nervous System Neoplasms/metabolism ; Central Nervous System Neoplasms/pathology ; Central Nervous System Neoplasms/therapy ; Drug Resistance, Neoplasm ; Enhancer of Zeste Homolog 2 Protein ; Gene Expression Regulation, Neoplastic ; Glioma/genetics ; Glioma/metabolism ; Glioma/pathology ; Glioma/therapy ; Humans ; MicroRNAs ; Oncogenes ; Polycomb Repressive Complex 2/genetics ; Polycomb Repressive Complex 2/metabolism ; RNA, Long Noncoding
Chemical Substances	MicroRNAs ; RNA, Long Noncoding ; EZH2 protein, human (EC 2.1.1.43) ; Enhancer of Zeste Homolog 2 Protein (EC 2.1.1.43) ; Polycomb Repressive Complex 2 (EC 2.1.1.43)
Language	English
Publishing date	2016-01-15
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2015.09.080
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Article: Functional roles of enhancer of zeste homolog 2 in gliomas

Yin, Yatao / Shuwei Qiu / Ying Peng

Gene. 2016 Jan. 15, v. 576, no. 1

2016

Abstract	Gliomas are the most common and lethal type of primary malignant brain tumor. Due to the infiltrative nature and high resistance to standard first line treatment with combinations of radiation and chemotherapy, the prognosis of patient is very poor. Recently, accumulated evidence suggests that enhancer of zeste homolog 2 (EZH2) serves as an oncogene and is involved in multiple glioma cell processes, including cell cycle, invasion, glioma stem cell maintenance, drug and radiotherapy resistance and so on. In this review, we will focus on updating current knowledge of EZH2 in gliomas. Moreover, the regulation of EZH2 by microRNAs and long non-coding RNAs and the therapeutic strategies targeting EZH2 for gliomas will also be discussed.
Keywords	brain ; cell cycle ; drug therapy ; drugs ; microRNA ; non-coding RNA ; oncogenes ; patients ; prognosis ; radiotherapy ; stem cells
Language	English
Dates of publication	2016-0115
Size	p. 189-194.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2015.09.080
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Article ; Online: Complete mesogastric excision for locally advanced gastric cancer: short-term outcomes of a randomized clinical trial.

Xie, Daxing / Shen, Jie / Liu, Liang / Cao, Beibei / Wang, Yatao / Qin, Jichao / Wu, Jianhong / Yan, Qun / Hu, Yuanlong / Yang, Chuanyong / Cao, Zhixin / Hu, Junbo / Yin, Ping / Gong, Jianping

Cell reports. Medicine

2021 Volume 2, Issue 3, Page(s) 100217

Abstract: Implementation of complete mesogastric excision in gastric cancer surgery, named D2 lymphadenectomy plus complete mesogastric excision (D2+CME), has recently been proposed as an optimal procedure. However, the safety and efficacy of D2+CME remain ... ...

Abstract	Implementation of complete mesogastric excision in gastric cancer surgery, named D2 lymphadenectomy plus complete mesogastric excision (D2+CME), has recently been proposed as an optimal procedure. However, the safety and efficacy of D2+CME remain uncertain. In this randomized controlled trial, patients receiving D2+CME exhibit less intraoperative blood loss, more lymph node harvesting, and earlier postoperative flatus than patients receiving conventional D2 radical surgery. Univariate Cox regression analysis reveals that the risk ratio for postoperative flatus in D2+CME group is 1.247 (p = 0.044). Overall postoperative complications are comparable between the two groups, but complications are significantly less severe in the D2+CME group than the D2 group (Clavien-Dindo classification grade ≥ IIIa: 4 D2+CME patients [11.8%] versus 9 D2 patients [33.3%]; p = 0.041). In conclusion, our work shows that D2+CME is associated with better short-term outcomes and surgical safety than conventional D2 dissection for patients with advanced gastric cancer.
MeSH term(s)	Adult ; Blood Loss, Surgical/physiopathology ; Blood Loss, Surgical/prevention & control ; Disease Progression ; Female ; Flatulence/diagnosis ; Flatulence/etiology ; Flatulence/physiopathology ; Gastrectomy/methods ; Humans ; Lymph Node Excision/methods ; Lymph Nodes/pathology ; Lymph Nodes/surgery ; Male ; Mesentery/pathology ; Mesentery/surgery ; Middle Aged ; Odds Ratio ; Patient Safety ; Postoperative Complications/diagnosis ; Postoperative Complications/physiopathology ; Stomach/pathology ; Stomach/surgery ; Stomach Neoplasms/mortality ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery ; Survival Analysis ; Treatment Outcome
Language	English
Publishing date	2021-03-16
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ISSN	2666-3791
ISSN (online)	2666-3791
DOI	10.1016/j.xcrm.2021.100217
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