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  1. Book: Clinical otology and audiology

    Browning, George G.

    1998  

    Author's details G. G. Browning
    Language English
    Size VIII, 216 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Butterworth-Heinemann
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT009214711
    ISBN 0-7506-3373-5 ; 978-0-7506-3373-4
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Measuring benefit from non-surgical interventions in otolaryngology for different conditions, using the revised 5-factor Glasgow Benefit Inventory.

    Kubba, Haytham / Whitmer, William M / Browning, George G

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

    2022  Volume 48, Issue 1, Page(s) 25–31

    Abstract: Objectives: The Glasgow Benefit Inventory (GBI) has been extensively used to report the benefit from otolaryngological surgery. Benefit from non-surgical management has not been reported, despite this being the outcome of most otolaryngology and ... ...

    Abstract Objectives: The Glasgow Benefit Inventory (GBI) has been extensively used to report the benefit from otolaryngological surgery. Benefit from non-surgical management has not been reported, despite this being the outcome of most otolaryngology and audiology consultations.
    Design: GBI responses from 4543 adults from the Scottish ENT Outcome Study were categorised by diagnosis. Benefit scores for different interventions within diagnostic categories for which surgery was not a potential management are reported using the revised 5-factor Glasgow Benefit Inventory (GBI-5F; 15 questions and 5 factors).
    Setting: Adult otolaryngology outpatient clinics in six university hospitals.
    Participants: Adults seen with conditions that had no surgical option and given non-surgical management.
    Results: Overall, 80% of participants managed in Scottish Ear Nose and Throat Outcome Study (SENTOS) did not have surgery. A total of 1373 (30%) participants with various diagnoses were given reassurance and advice with no active intervention. There was no change in their GBI-5F total or factor scores, suggesting that they did not come to harm from their lack of active intervention. Hearing aids for bilateral sensorineural hearing loss gave greater benefit than reassurance in all factors, though individuals with a conductive impairment reported greater benefit in the Quality of life factor than those with a sensorineural impairment. Hearing aids and maskers produced benefit in the Support factor for patients with tinnitus. Epley's manoeuvre for benign paroxysmal positional vertigo gave benefit in the total score and the Quality of life factor compared with reassurance. Systemic medication for laryngo-pharyngeal reflux and topical medication for otitis externa gave no greater benefit in any factor or the total score compared with reassurance.
    Conclusion: The GBI-5F and its five factors give useful information for reporting the benefit of non-surgical interventions in adult otolaryngology and audiology clinics.
    MeSH term(s) Adult ; Humans ; Quality of Life ; Pharynx ; Otolaryngology ; Benign Paroxysmal Positional Vertigo ; Outcome Assessment, Health Care ; Treatment Outcome
    Language English
    Publishing date 2022-10-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2205891-6
    ISSN 1749-4486 ; 1749-4478 ; 0307-7772 ; 1365-2273
    ISSN (online) 1749-4486
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    DOI 10.1111/coa.13992
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Updated ENT

    Browning, George G.

    1994  

    Author's details G. G. Browning
    Keywords Otorhinolaryngologic Diseases
    Language English
    Size XIV, 190 S. : zahlr. Ill., graph. Darst.
    Edition 3. ed.
    Publisher Butterworth-Heinemann
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT006542964
    ISBN 0-7506-1921-X ; 978-0-7506-1921-9
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Updated Ent

    Browning, George G.

    1987  

    Keywords Otorhinolaryngologic Diseases
    Size VIII, 184 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Butterworths
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT003096852
    ISBN 0-407-00590-0 ; 978-0-407-00590-7
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Revised 15-item Glasgow Benefit Inventory with five factors based on analysis of a large population study of medical and surgical otorhinolaryngological interventions.

    Browning, George G / Kubba, Haytham / Whitmer, William M

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

    2020  Volume 46, Issue 1, Page(s) 213–221

    Abstract: Objectives: To review, using confirmatory factor analysis, the widely used 18-question Glasgow Benefit Inventory [GBI] that has three factors. Thereafter to develop, using exploratory factor analysis, a more coherent, revised version of the GBI.: ... ...

    Abstract Objectives: To review, using confirmatory factor analysis, the widely used 18-question Glasgow Benefit Inventory [GBI] that has three factors. Thereafter to develop, using exploratory factor analysis, a more coherent, revised version of the GBI.
    Design: Confirmatory and exploratory factor analysis of a large national GBI data set of ORL interventions.
    Setting: Adult otorhinolaryngology outpatient clinics in six University Hospital departments.
    Participants: One thousand nine hundred eighty adult patients who had complete GBI data and who underwent an active (medical or surgical) intervention, out of the total data set of 9005 patients from the original Scottish ENT Outcome Study [SENTOS].
    Results: One of the 18 questions was discarded from the data base because it was not answered by 8% of respondents. Two of the original factors remained (Physical Health, renamed General Health, and Social Support, renamed Support). The General factor was split into three new factors (Quality of Life, Self-Confidence and Social Involvement). The three new factors were found to give additional information regarding the area of benefit. This reduced number of questions does not make any material difference to the results of the >196 existing GBI papers in the literature.
    Conclusion: A 15-question GBI with five factors is provided that is more explanatory of the areas of benefit.
    MeSH term(s) Adolescent ; Adult ; Aged ; Ambulatory Care ; Databases, Factual ; Factor Analysis, Statistical ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Otorhinolaryngologic Surgical Procedures/psychology ; Otorhinolaryngologic Surgical Procedures/statistics & numerical data ; Outcome Assessment, Health Care ; Quality of Life ; Reproducibility of Results ; Self Concept ; Social Behavior ; Social Support ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2020-09-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2205891-6
    ISSN 1749-4486 ; 1749-4478 ; 0307-7772 ; 1365-2273
    ISSN (online) 1749-4486
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    DOI 10.1111/coa.13649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Clinical otology and audiology

    Browning, George G.

    1986  

    Keywords Hearing Disorders / diagnosis ; Hearing Disorders / therapy ; Hearing Tests
    Size 272 S. : graph. Darst.
    Publisher Butterworths
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT002806674
    ISBN 0-407-00285-5 ; 978-0-407-00285-2
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Bone and Renal Health in Infants With or Without Breastmilk Exposure to Tenofovir-Based Maternal Antiretroviral Treatment in the PROMISE Randomized Trial.

    Vhembo, Tichaona / Baltrusaitis, Kristin / Tierney, Camlin / Owor, Maxensia / Dadabhai, Sufia / Violari, Avy / Theron, Gerhard / Moodley, Dhayendre / Mukwasi-Kahari, Cynthia / George, Kathleen / Shepherd, John / Siberry, George K / Browning, Renee / Fowler, Mary Glenn / Stranix-Chibanda, Lynda

    Journal of acquired immune deficiency syndromes (1999)

    2023  Volume 93, Issue 5, Page(s) 431–437

    Abstract: ... Results: Of 400 enrolled infants, the mean (SD; n) for entry LS-BMC was 1.68 g (0.35; n = 363) and CrCl ... on their assigned HIV prevention strategy. The mean (SD) Week 26 LS-BMC was 2.64 g (0.48) for mART and 2.77 g (0.44 ... for iNVP; mean difference (95% confidence interval [CI]) -0.13 g (-0.22 to -0.04), P = 0.007, n = 375/398 ...

    Abstract Background: We assessed bone and kidney outcomes in infants randomized postdelivery as mother-infant pairs within the IMPAACT PROMISE trial to maternal tenofovir disoproxil fumarate-based antiretroviral treatment (mART) or infant nevirapine prophylaxis (iNVP) to prevent breastfeeding HIV transmission.
    Methods: Infants were coenrolled in the P1084s substudy on randomization day and followed through Week 74. Lumbar spine bone mineral content (LS-BMC) was assessed at entry (6-21 age days) and Week 26 by dual-energy x-ray absorptiometry. Creatinine clearance (CrCl) was calculated at entry; Weeks 10, 26, and 74. Student t tests compared mean LS-BMC and CrCl at Week 26 and mean change from entry between arms.
    Results: Of 400 enrolled infants, the mean (SD; n) for entry LS-BMC was 1.68 g (0.35; n = 363) and CrCl was 64.2 mL/min/1.73 m 2 (24.6; n = 357). At Week 26, 98% of infants were breastfeeding and 96% on their assigned HIV prevention strategy. The mean (SD) Week 26 LS-BMC was 2.64 g (0.48) for mART and 2.77 g (0.44) for iNVP; mean difference (95% confidence interval [CI]) -0.13 g (-0.22 to -0.04), P = 0.007, n = 375/398 (94%). Mean absolute (-0.14 g [-0.23 to -0.06]) and percent (-10.88% [-18.53 to -3.23]) increase in LS-BMC from entry was smaller for mART than iNVP. At Week 26, the mean (SD) CrCl was 130.0 mL/min/1.73 m 2 (34.9) for mART vs. 126.1 mL/min/1.73 m 2 (30.0) for iNVP; mean difference (95% CI) 3.8 (-3.0 to 10.7), P = 0.27, n = 349/398 (88%).
    Conclusion: Week 26 mean LS-BMC was lower in infants in the mART group compared with the iNVP group. However, this difference (∼0.23 g) was less than one-half SD, considered potentially clinically relevant. No infant renal safety concerns were observed.
    MeSH term(s) Female ; Humans ; Tenofovir/therapeutic use ; Tenofovir/pharmacology ; Anti-HIV Agents/therapeutic use ; Anti-HIV Agents/pharmacology ; Milk, Human ; HIV Infections/drug therapy ; HIV Infections/prevention & control ; Anti-Retroviral Agents/therapeutic use ; Nevirapine/therapeutic use ; Bone Density ; Kidney ; Lumbar Vertebrae
    Chemical Substances Tenofovir (99YXE507IL) ; Anti-HIV Agents ; Anti-Retroviral Agents ; Nevirapine (99DK7FVK1H)
    Language English
    Publishing date 2023-05-18
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 0897-5965 ; 0894-9255 ; 1525-4135
    DOI 10.1097/QAI.0000000000003218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hearing in Adults: A Digital Reprint of the Main Report From the MRC National Study of Hearing.

    Akeroyd, Michael A / Browning, George G / Davis, Adrian C / Haggard, Mark P

    Trends in hearing

    2019  Volume 23, Page(s) 2331216519887614

    Abstract: The 1011-page book, Hearing in Adults, published in 1995, contains the fullest report of the United Kingdom’s Medical Research Council National Study of Hearing. It was designed to determine the prevalence and distribution in Great Britain of ... ...

    Abstract The 1011-page book, Hearing in Adults, published in 1995, contains the fullest report of the United Kingdom’s Medical Research Council National Study of Hearing. It was designed to determine the prevalence and distribution in Great Britain of audiometrically measured hearing loss as a function of age, gender, occupation, and noise exposure. The study’s size, quality, and breadth made it unique when it was done in the 1980s. These qualities remain, and its data are still the primary U.K. source for the prevalence of auditory problems. However, only 550 copies were printed, and the book is essentially unobtainable today. We describe here a fully searchable, open-access, digital (PDF) “reprinting” of Hearing in Adults, summarizing the study’s design and the book’s contents, together with a brief commentary in the light of subsequent developments.
    MeSH term(s) Adult ; Audiometry ; Female ; Hearing ; Hearing Loss/epidemiology ; Humans ; Male ; Middle Aged ; Prevalence ; United Kingdom/epidemiology
    Language English
    Publishing date 2019-12-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2778755-2
    ISSN 2331-2165 ; 2331-2165
    ISSN (online) 2331-2165
    ISSN 2331-2165
    DOI 10.1177/2331216519887614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Evidence-based medicine is a top medical milestone.

    Browning, George G

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

    2007  Volume 32, Issue 1, Page(s) 67

    MeSH term(s) England ; Evidence-Based Medicine/history ; History, 19th Century ; Humans ; Otolaryngology/history
    Language English
    Publishing date 2007-02
    Publishing country England
    Document type Historical Article ; Letter
    ZDB-ID 2205891-6
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    DOI 10.1111/j.1365-2273.2007.01393.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A relevant or irrelevant tonsillectomy trial?

    George, G Browning

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

    2007  Volume 32, Issue 4, Page(s) 286

    MeSH term(s) Acute Disease ; Adolescent ; Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Clinical Trials as Topic ; Finland ; Humans ; Middle Aged ; Pharyngitis/drug therapy ; Pharyngitis/microbiology ; Pharyngitis/surgery ; Recurrence ; Streptococcal Infections/drug therapy ; Streptococcal Infections/surgery ; Streptococcus pyogenes ; Tonsillectomy ; Tonsillitis/drug therapy ; Tonsillitis/microbiology ; Tonsillitis/surgery ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2007-08
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2205891-6
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    DOI 10.1111/j.1365-2273.2007.01495.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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