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  1. Book ; Online ; E-Book: Opioid Use in Critical Care

    Pascual, Jose L. / Gaulton, Timothy G.

    A Practical Guide

    2021  

    Title variant Opioid Use in Critical Care
    Keywords Opiacis ; Ús terapèutic
    Language English
    Size 1 online resource (291 pages)
    Publisher Springer International Publishing AG
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-77399-X ; 3-030-77398-1 ; 978-3-030-77399-1 ; 978-3-030-77398-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The older adult with preexisting neurocognitive disorder.

    Gaulton, Timothy G

    Current opinion in anaesthesiology

    2019  Volume 32, Issue 3, Page(s) 438–442

    Abstract: Purpose of review: With the ageing population, there is an increasing number of patients with a neurocognitive disorder (NCD) who undergo surgical procedures. The aim of this review is to highlight the epidemiology of preoperative NCD.: Recent ... ...

    Abstract Purpose of review: With the ageing population, there is an increasing number of patients with a neurocognitive disorder (NCD) who undergo surgical procedures. The aim of this review is to highlight the epidemiology of preoperative NCD.
    Recent findings: New guidelines have defined NCD into mild NCD and major NCD consistent with terminology from the wider clinical community. Several assessment tools have been used in the preoperative setting to identify patients with evidence of cognitive decline. NCD prior to surgery remains a major risk factor postoperative delirium.
    Summary: Cognitive dysfunction is common prior to surgery. Awareness of dysfunction, especially when taking care of older adults, is critical given the high risk of complications in this population.
    MeSH term(s) Aged ; Aging/physiology ; Evidence-Based Medicine/methods ; Evidence-Based Medicine/standards ; Humans ; Neurocognitive Disorders/diagnosis ; Neurocognitive Disorders/epidemiology ; Neurocognitive Disorders/physiopathology ; Postoperative Complications/diagnosis ; Postoperative Complications/etiology ; Postoperative Complications/psychology ; Practice Guidelines as Topic ; Preoperative Care/methods ; Preoperative Care/standards ; Preoperative Period ; Prevalence ; Psychometrics ; Risk Factors ; Surgical Procedures, Operative/adverse effects
    Language English
    Publishing date 2019-08-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0000000000000737
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    Zs.A 2564: Show issues Location:
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  3. Article ; Online: Trends in personal protective equipment use by clinicians performing airway procedures for patients with coronavirus disease 2019 in the USA from the intubateCOVID registry.

    Gaulton, Timothy G / Neuman, Mark D

    British journal of anaesthesia

    2021  Volume 126, Issue 5, Page(s) e184–e186

    MeSH term(s) Adult ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Female ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Intubation, Intratracheal/standards ; Intubation, Intratracheal/trends ; Male ; Middle Aged ; Personal Protective Equipment/standards ; Personal Protective Equipment/trends ; Physicians/standards ; Physicians/trends ; United States/epidemiology
    Language English
    Publishing date 2021-02-02
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.01.019
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    Uk I Zs.80: Show issues Location:
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  4. Article ; Online: Imaging the pulmonary vasculature in acute respiratory distress syndrome.

    Gaulton, Timothy G / Xin, Yi / Victor, Marcus / Nova, Alice / Cereda, Maurizio

    Nitric oxide : biology and chemistry

    2024  Volume 147, Page(s) 6–12

    Abstract: Acute respiratory distress syndrome (ARDS) is characterized by a redistribution of regional lung perfusion that impairs gas exchange. While speculative, experimental evidence suggests that perfusion redistribution may contribute to regional inflammation ... ...

    Abstract Acute respiratory distress syndrome (ARDS) is characterized by a redistribution of regional lung perfusion that impairs gas exchange. While speculative, experimental evidence suggests that perfusion redistribution may contribute to regional inflammation and modify disease progression. Unfortunately, tools to visualize and quantify lung perfusion in patients with ARDS are lacking. This review explores recent advances in perfusion imaging techniques that aim to understand the pulmonary circulation in ARDS. Dynamic contrast-enhanced computed tomography captures first-pass kinetics of intravenously injected dye during continuous scan acquisitions. Different contrast characteristics and kinetic modeling have improved its topographic measurement of pulmonary perfusion with high spatial and temporal resolution. Dual-energy computed tomography can map the pulmonary blood volume of the whole lung with limited radiation exposure, enabling its application in clinical research. Electrical impedance tomography can obtain serial topographic assessments of perfusion at the bedside in response to treatments such as inhaled nitric oxide and prone position. Ongoing technological improvements and emerging techniques will enhance lung perfusion imaging and aid its incorporation into the care of patients with ARDS.
    MeSH term(s) Humans ; Respiratory Distress Syndrome/diagnostic imaging ; Respiratory Distress Syndrome/physiopathology ; Lung/diagnostic imaging ; Lung/blood supply ; Tomography, X-Ray Computed ; Pulmonary Circulation ; Perfusion Imaging/methods ; Animals
    Language English
    Publishing date 2024-04-06
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1362794-6
    ISSN 1089-8611 ; 1089-8603
    ISSN (online) 1089-8611
    ISSN 1089-8603
    DOI 10.1016/j.niox.2024.04.004
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    Zs.A 4677: Show issues Location:
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  5. Article ; Online: Motor Vehicle Crash Risk among Adults Undergoing General Surgery: A Retrospective Case-crossover Study.

    Gaulton, Timothy G / Pfeiffer, Melissa R / Metzger, Kristina B / Curry, Allison E / Neuman, Mark D

    Anesthesiology

    2023  Volume 138, Issue 6, Page(s) 602–610

    MeSH term(s) Humans ; Aged ; Retrospective Studies ; Cross-Over Studies ; Automobile Driving ; Risk Factors ; Accidents, Traffic ; Motor Vehicles
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004558
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    Zs.MO 199: Show issues

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  6. Article ; Online: Reporting and representation of obesity in randomized controlled trials of noninvasive oxygenation strategies in hypoxemic respiratory failure.

    Gaulton, Timothy G / Berra, Lorenzo / Ferreyro, Bruno L / Cereda, Maurizio

    Internal and emergency medicine

    2022  Volume 17, Issue 8, Page(s) 2437–2439

    MeSH term(s) Humans ; Randomized Controlled Trials as Topic ; Respiratory Insufficiency/therapy ; Noninvasive Ventilation ; Obesity/complications ; Obesity/therapy ; Hypoxia/therapy ; Oxygen Inhalation Therapy
    Language English
    Publishing date 2022-10-14
    Publishing country Italy
    Document type Letter
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03118-2
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    Zs.A 6673: Show issues Location:
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  7. Article ; Online: Association of hospitalization with driving reduction and cessation in older adults.

    Gaulton, Timothy G / Neuman, Mark D / Brown, Rebecca T / Betz, Marian E

    Journal of the American Geriatrics Society

    2021  Volume 69, Issue 8, Page(s) 2231–2239

    Abstract: Background: Driving has not been considered as part of the social cost of acute illness and may go unnoticed in the post-hospital care of older adults. Decreases in driving after hospitalization and at-risk populations have not been investigated.: ... ...

    Abstract Background: Driving has not been considered as part of the social cost of acute illness and may go unnoticed in the post-hospital care of older adults. Decreases in driving after hospitalization and at-risk populations have not been investigated.
    Objective: To determine the association between driving reduction and cessation and hospitalization in older adults by using nationally representative data.
    Design: Retrospective cohort analysis.
    Setting: Health and Retirement Study survey from 2004 to 2014.
    Participants: Adults aged 65 years and older who were able to drive and had an available car (n = 12,110; 40,364 interviews).
    Measurements: Self-report of a hospitalization requiring an overnight stay, changes in driving patterns including driving cessation or limitations over a 2-year period, comorbid conditions, health utilization, and behaviors.
    Results: Of hospitalizations in adults aged 65 years and older, 22% were associated with a decrease in driving patterns within 2 years. The relative risk of a reduction or cessation in driving was 1.62 (95% CI: 1.54, 1.70, p < 0.001) when there was a hospitalization compared with when a hospitalization did not occur. Baseline functional, cognitive, and visual impairment, fair or poor self-rated health, and diabetes were identified as independent risk factors for decreased driving patterns after hospitalization.
    Conclusions: Changes in driving patterns are common after a hospitalization in older adults. The findings suggest that driving, although not a current goal of post-hospital care, is important to the continued autonomy and community mobility of older adults and needs to be addressed as part of discharge planning and their recovery.
    MeSH term(s) Aftercare/methods ; Aged ; Aged, 80 and over ; Automobile Driving/statistics & numerical data ; Female ; Health Status ; Hospitalization/statistics & numerical data ; Humans ; Male ; Patient Discharge ; Retrospective Studies ; Risk Factors ; Surveys and Questionnaires
    Language English
    Publishing date 2021-04-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17178
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    Ud II Zs.168: Show issues Location:
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  8. Article ; Online: Prevalence and Multivariable Factors Associated With Preoperative Cognitive Impairment in Outpatient Surgery in the United States.

    Gaulton, Timothy G / Eckenhoff, Roderic G / Neuman, Mark D

    Anesthesia and analgesia

    2019  Volume 129, Issue 1, Page(s) e5–e7

    Abstract: Preoperative cognitive impairment increases the risk of adverse events after surgery but its prevalence in outpatient surgery has not been defined. We aimed to determine the prevalence and multivariable factors associated with cognitive impairment in ... ...

    Abstract Preoperative cognitive impairment increases the risk of adverse events after surgery but its prevalence in outpatient surgery has not been defined. We aimed to determine the prevalence and multivariable factors associated with cognitive impairment in individuals who present for outpatient surgery. We used data from the Health and Retirement Study, a longitudinal panel survey of older Americans. Of 1836 participants who reported having outpatient surgery, we found that 16.1% had evidence of cognitive impairment. Significant multivariable factors associated with preoperative cognitive impairment included non-Hispanic African American race, prior stroke, preoperative functional dependence, and lower socioeconomic status and education level.
    MeSH term(s) Aged ; Aged, 80 and over ; Ambulatory Surgical Procedures/adverse effects ; Cognition ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/psychology ; Female ; Humans ; Male ; Mental Health ; Prevalence ; Risk Assessment ; Risk Factors ; United States
    Language English
    Publishing date 2019-06-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000004035
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    Uk I Zs.78: Show issues Location:
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    Zs.MO 149: Show issues

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  9. Article ; Online: Association Between Obesity, Age, and Functional Decline in Survivors of Cardiac Surgery.

    Gaulton, Timothy G / Neuman, Mark D

    Journal of the American Geriatrics Society

    2017  Volume 66, Issue 1, Page(s) 127–132

    Abstract: Background/objectives: Little is known about the effect of obesity on functional decline after cardiac surgery, especially in elderly adults. Our goal was to determine the association between obesity and functional decline in the 2 years after cardiac ... ...

    Abstract Background/objectives: Little is known about the effect of obesity on functional decline after cardiac surgery, especially in elderly adults. Our goal was to determine the association between obesity and functional decline in the 2 years after cardiac surgery and the interaction between obesity and age.
    Design: Retrospective cohort study.
    Setting: The Health and Retirement Study, 2004-2014.
    Participants: U.S. adults aged 50 and older who indicated having cardiac surgery and had a body mass index (BMI) of 18.5 kg/m
    Measurements: BMI was classified as normal or overweight (18.5-29.9 kg/m
    Results: Respondents had a median age of 71, 59.3% were female, and 34.3% were obese. Obese respondents had a higher incidence of ADL decline (22.4%) than those who were not obese (17.1%) (P = .007). In the multivariable analysis of our full cohort, obesity was not associated with ADL decline (odds ratio (OR)=1.20, 95% confidence interval (CI)=0.90-1.59, P = .21) after cardiac surgery, although obese respondents aged 50 to 79 had greater odds of ADL decline (OR=1.45, 95% CI=1.06-2.00, P = .02). Obese respondents aged 80 and older had nonstatistically significantly lower odds of ADL decline (OR=0.61, 95% CI=0.30-1.24, P = .18) compared to non-obese respondents.
    Conclusion: The association between obesity and postoperative functional decline in survivors of cardiac surgery differed according to age. Additional research is needed to identify interventions to improve outcomes in groups of older adults in whom obesity may increase the risk of postoperative functional decline.
    MeSH term(s) Activities of Daily Living ; Aged ; Aged, 80 and over ; Body Mass Index ; Cardiac Surgical Procedures/statistics & numerical data ; Female ; Humans ; Incidence ; Male ; Obesity/epidemiology ; Postoperative Period ; Retrospective Studies ; Survivors/statistics & numerical data
    Language English
    Publishing date 2017-11-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.15160
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  10. Article ; Online: First-Pass Kinetics Model to Estimate Pulmonary Perfusion by EIT During Uninterrupted Breathing.

    Victor, Marcus / Xin, Yi / Alcala, Glasiele / Gaulton, Timothy / Costa, Eduardo / Winkler, Tilo / Berra, Lorenzo / Amato, Marcelo / Cereda, Maurizio

    American journal of respiratory and critical care medicine

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202310-1919LE
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