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Article ; Online: Association among Polydisperse Aerodynamic Size of Bioaerosols, Biodiversity and Urbanization in Kindergartens.

Lin, Tzu-Hsien / Chou, Ying-Hsiang / Hsu, Tzu-Yu / Hung, Chun-Hui / Lai, Chane-Yu

2024 , Page(s) 142333

Abstract: The aerodynamic sizes of bioaerosols may significantly affect their behaviors, respiratory deposition and biodiversity. The respirable bacterial size, biodiversity, and human-associated bacteria (HAB) related bioaerosols were evaluated at three ... ...

Abstract	The aerodynamic sizes of bioaerosols may significantly affect their behaviors, respiratory deposition and biodiversity. The respirable bacterial size, biodiversity, and human-associated bacteria (HAB) related bioaerosols were evaluated at three kindergartens in Taiwan. Kindergartens A, B, and C were in urban, semi-urban, and rural areas, respectively. A six-stage viable Andersen cascade impactor was used to collect bioaerosols and to determine their size distributions. The geometric mean diameter (GMD), geometric standard deviation (GSD), heat maps, and uniformity were used to evaluate the association of bacteria characteristics. A BD Phoenix-100 automated interpretation system was used to identify the airborne bacteria species. The results revealed that 1,425 colonies of the sampled airborne bacteria contained 63 species in 29 genera, and overall, 63.0% were HABs. The most abundant phylum was Actinobacteria (56.6+22.2%) and Firmicutes (31.6+22.3%), and from the taxonomic analysis, both airborne Micrococcus and the Staphylococcus aureus are the dominant genus. All the bacteria aerodynamic particle size distributions were polydisperse distributions. The heat map and uniformity analysis had revealed most of the sampled bioaerosols distributed between 1.1∼3.3 μm, and most of the polydisperse airborne Streptococcus spp. had a size in the respirable range, due to urbanization, they have potentially contributed to respiratory risk in the kindergartens. The Shannon diversity index (H) and inverse Simpson diversity index (D) of the bioaerosols in urban kindergarten were negatively correlated with GMD and GSD. The Pearson correlations revealed that the kindergarten in the rural area, with a higher temperature, a lower relative humidity, and a lower CO
Language	English
Publishing date	2024-05-15
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2024.142333
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Article ; Online: Solar farm policy and farmland price - A land zoning perspective.

Chang, Hung-Hao / Lin, Tzu-Chin

Journal of environmental management

2023 Volume 344, Page(s) 118454

Abstract: Photovoltaic or solar energy is recognized as a significant source of renewable energy on a global scale. The utilization of ground-mounted solar panels is closely associated with the use of farmland, as solar power generation typically requires vast ... ...

Abstract	Photovoltaic or solar energy is recognized as a significant source of renewable energy on a global scale. The utilization of ground-mounted solar panels is closely associated with the use of farmland, as solar power generation typically requires vast expanses of farmland. While previous studies have explored the use of price incentives to regulate the adoption of solar panels, little is known about the impact of land zoning policies on farmland prices. The relationship between farmland use policies and farmland prices is well-documented, with policies often capitalizing into the value of the land across various countries. The deployment of ground-mounted solar panels has raised concerns about the potential loss of farmland and the degradation of the farming environment. However, the policy debate has largely overlooked the price capitalization effect of solar panel installations. In an effort to mitigate the adverse effects of solar panels on agriculture, the Taiwanese government implemented revised zoning regulations that impose stricter limitations on small-scale ground-mounted type solar panels installed on farmland. As a result of this policy reform, solar panels are no longer permitted on farmland areas measuring less than 660 square meters. While it is expected that the installation of solar panels will slow down, the resulting price effects on farmland remain poorly understood. This paper measures the impact of the land zoning regulation on farmland prices in Taiwan. By utilizing nationwide data on farmland transactions and employing the difference-in-differences method, we discover that the tightened regulations pertaining to solar panel installation have led to a 21.8% reduction in farmland prices. Furthermore, the negative price effect is found to be least pronounced in high-productivity farmland. We also find that the decline in prices commenced two months after the reform and continued to intensify over time. Additionally, we identify a distributional effect concerning price, whereby farmland with higher prices per hectare experiences the most significant impact. Consequently, our study contributes an empirical analysis that confirms the substantial price capitalization effects of land zoning policies on farmland.
MeSH term(s)	Farms ; Agriculture ; Renewable Energy ; Solar Energy ; Policy
Language	English
Publishing date	2023-06-21
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.118454
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Article ; Online: Blood RNA-sequencing analysis in acrylamide-induced neurotoxicity and depressive symptoms in rats.

Chen, Yng-Tay / Lin, Tzu-Jung / Hung, Chia-Yu

Environmental toxicology

2023 Volume 39, Issue 4, Page(s) 2316–2325

Abstract: Acrylamide (ACR) is a by-product of the Maillard reaction, which occurs when food reacts at high temperatures. Occupational exposure is a risk factor for chronic ACR toxicity. ACR may cause neurotoxicity and depressive symptoms with high concentration in ...

Abstract	Acrylamide (ACR) is a by-product of the Maillard reaction, which occurs when food reacts at high temperatures. Occupational exposure is a risk factor for chronic ACR toxicity. ACR may cause neurotoxicity and depressive symptoms with high concentration in the blood; however, the underlying mechanism remains unknown. We showed the rats developed neurotoxic symptoms after being fed with ACR for 28 days, such as reduced activity and hind limb muscle weakness. We investigated whether ACR exposure causes gene expression differences by blood RNA sequencing and analyzed the differential expression of depressive symptoms-associated genes. The result indicated that IFN-γ the key regulator of neurotoxicity and depressive symptoms was induced by ACR. ACR induced the ubiquitin-mediated proteolysis pathway and JAK/STAT pathways gene expression. ACR upregulated the expression of IFN-γ, inducing neuroinflammation and neurotoxicity. ACR also upregulated the expression of JAK2, STAT1, PI3K, AKT, IκBα, UBE2D4, NF-κB, TNF-α, and iNOS in rat brain tissues and Neuro-2a cells. Thus, IFN-γ induction by ACR may induce depressive symptoms, and the ubiquitin-mediated proteolysis pathway and JAK/STAT pathways may involve in ACR neurotoxicity and depressive symptoms.
MeSH term(s)	Rats ; Animals ; Acrylamide/toxicity ; Depression/chemically induced ; Depression/genetics ; Antioxidants/metabolism ; Neurotoxicity Syndromes/genetics ; Ubiquitins ; RNA
Chemical Substances	Acrylamide (20R035KLCI) ; Antioxidants ; Ubiquitins ; RNA (63231-63-0)
Language	English
Publishing date	2023-12-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	1463449-1
ISSN	1522-7278 ; 1520-4081
ISSN (online)	1522-7278
ISSN	1520-4081
DOI	10.1002/tox.24112
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Article ; Online: Corrigendum to "A boy who can puff his neck: Bilateral internal jugular phlebectasia" [PEDN 63 (1) (2022) 84-85].

Chen, Tzu-Ying / Wei, Chin-Hung / Lin, Yi-Chih

Pediatrics and neonatology

2022 Volume 63, Issue 4, Page(s) 441

Language	English
Publishing date	2022-05-14
Publishing country	Singapore
Document type	Published Erratum
ZDB-ID	2441816-X
ISSN	2212-1692 ; 1875-9572
ISSN (online)	2212-1692
ISSN	1875-9572
DOI	10.1016/j.pedneo.2022.04.001
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Article ; Online: Swivel-HEPA-ETT (SHE) bougie and HEPA-ETT (HE) methods for safe intubation while managing patients with COVID-19.

Lin, Li-Wei / Hung, Tzu-Yao

Emergency medicine journal : EMJ

2020 Volume 37, Issue 5, Page(s) 256–257

MeSH term(s)	COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Emergency Medicine ; Filtration ; Humans ; Intubation, Intratracheal/methods ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Practice Guidelines as Topic ; Self Administration ; Self Care
Keywords	covid19
Language	English
Publishing date	2020-04-15
Publishing country	England
Document type	Letter
ZDB-ID	2040124-3
ISSN	1472-0213 ; 1472-0205
ISSN (online)	1472-0213
ISSN	1472-0205
DOI	10.1136/emermed-2020-209625
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Article ; Online: Influence of microclimate control on the growth of asparagus under greenhouse in tropical climates.

Hung, Kuo-An / Hsu, Yi-Wei / Chen, Yu-Cheng / Lin, Tzu-Ping

International journal of biometeorology

2023 Volume 67, Issue 7, Page(s) 1225–1235

Abstract: High temperatures have become common in cities in Taiwan, and this phenomenon has spread to surrounding agricultural areas. Tainan, a city located in a tropical climate zone with agriculture as its primary development industry, is one of the cities ... ...

Abstract	High temperatures have become common in cities in Taiwan, and this phenomenon has spread to surrounding agricultural areas. Tainan, a city located in a tropical climate zone with agriculture as its primary development industry, is one of the cities considerably affected by the high temperature. High temperatures can reduce crop yields and even cause plant death, especially for vulnerable high-value crops, which are severely to microclimate conditions. Asparagus is a high-value crop that has long been cultivated in the Jiangjun District of Tainan. Recently, asparagus has been planted in greenhouses to protect against pests and natural disasters. However, the greenhouses can overheat. To identify the optimal growth environment for asparagus, this study applies vertical monitoring to record the temperature in the greenhouse and the soil moisture content of a control (canal irrigation) and an experimental (drip irrigation) group. When the surface layer of the soil exceeds 33°C, the tender stems of asparagus bloom readily, reducing its commercial value. Therefore, drip irrigation was conducted with cool water (26°C) to reduce soil temperature in summer and warm water (28°C) to increase soil temperature in winter. The study also recorded the growth of asparagus using daily yields measured by farmers during weighing and packing to understand the benefits of controlling the greenhouse microclimate. This study reports a correlation of 0.85 between asparagus yield and temperature and a correlation of 0.86 between asparagus yield and soil moisture content. The use of a drip irrigation system with a water temperature adjustment function not only saves up to 50% of water but also resulted in an average yield increase of 10% through maintaining stable soil moisture content and temperature. Therefore, the findings of this study can be applied to asparagus yields affected by high temperature and can solve the problems of poor quality in summer and low yield in winter.
MeSH term(s)	Tropical Climate ; Microclimate ; Soil ; Agriculture/methods ; Water ; Agricultural Irrigation
Chemical Substances	Soil ; Water (059QF0KO0R)
Language	English
Publishing date	2023-05-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	280324-0
ISSN	1432-1254 ; 0020-7128
ISSN (online)	1432-1254
ISSN	0020-7128
DOI	10.1007/s00484-023-02490-8
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Article: Re-evaluating the role of pelvic radiation in the age of modern precision medicine and systemic therapy.

Ke, Tao-Wei / Liao, Yu-Min / Chang, Sheng-Chi / Lin, Che-Hung / Chen, William Tzu-Liang / Liang, Ji-An / Chien, Chun-Ru

World journal of clinical oncology

2024 Volume 15, Issue 1, Page(s) 1–4

Abstract: The efficacy of pelvic radiation in the management of locally advanced stage rectal cancer has come under scrutiny in the context of modern precision medicine and systemic therapy as evidenced by recent clinical trials such as FOWARC ( ...

Abstract	The efficacy of pelvic radiation in the management of locally advanced stage rectal cancer has come under scrutiny in the context of modern precision medicine and systemic therapy as evidenced by recent clinical trials such as FOWARC (
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Editorial
ZDB-ID	2587357-X
ISSN	2218-4333
ISSN	2218-4333
DOI	10.5306/wjco.v15.i1.1
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Article ; Online: Comparison of ground reaction force among stride types in baseball pitching.

Chen, Shu-Wei / Tang, Wen-Tzu / Kung, Jung-Tang / Hung, Tsung-Ying / Lin, Wei-Hsuan / Chen, Yu-Lin / Burgee, Daniel J

Sports biomechanics

2024 , Page(s) 1–14

Abstract: This study aims to investigate the different ground reaction force (GRF) characteristics from different stride types. This study included 30 Taiwanese elite college and professional baseball pitchers. Each pitcher was classified into one of the following ...

Abstract	This study aims to investigate the different ground reaction force (GRF) characteristics from different stride types. This study included 30 Taiwanese elite college and professional baseball pitchers. Each pitcher was classified into one of the following stride types: tall and fall (TF), dip and drive (DD), or mixed (MX). Our findings indicated that DD pitchers pressed their bodies forward earlier than TF pitchers. In contrast, the GRF of the pivot leg of TF pitchers increased slowly in the first half of the stride phase and continued to increase even after the stride leg touched the ground. This type of continuous pressing in TF was different from that in DD and MX pitchers, which decreased rapidly into the arm-cocking & acceleration phases. We conclude that the lower extremities were used differently by TF, DD and MX pitchers. This information could serve as a training guideline for coaches and pitchers to enhance training effectiveness, while simultaneously lowering injury risks.
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Journal Article
ISSN	1752-6116
ISSN (online)	1752-6116
DOI	10.1080/14763141.2024.2315241
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Article ; Online: Sodium Glucose Transporter 2 Inhibitors Versus Metformin on Cardiovascular and Renal Outcomes in Patients With Diabetes With Low Cardiovascular Risk: A Nationwide Cohort Study.

Chang, Hao-Chih / Chen, Yun-Yu / Kuo, Tzu-Ting / Lin, Yenn-Jiang / Chien, Kuo-Liong / Chang, Hung-Yu / Hung, Chung-Lieh / Chung, Fa-Po

Journal of the American Heart Association

2024 Volume 13, Issue 8, Page(s) e032397

Abstract: Background: This study investigated whether initial SGLT2 (sodium-glucose cotransporter 2) inhibitor-based treatment is superior to metformin-based regimens as a primary prevention strategy among low-risk patients with diabetes.: Methods and results: ...

Abstract	Background: This study investigated whether initial SGLT2 (sodium-glucose cotransporter 2) inhibitor-based treatment is superior to metformin-based regimens as a primary prevention strategy among low-risk patients with diabetes. Methods and results: In this nationwide cohort study, a total of 38 496 patients with diabetes with low cardiovascular risk were identified (age 62.0±11.6 years, men 50%) from January 1 to December 31, 2016. Patients receiving SGLT2 inhibitors-based and metformin-based regimens were 1:2 matched by propensity score. Study outcomes included all-cause mortality, cardiovascular death, hospitalization for heart failure, stroke, and progression to end-stage renal disease. Compared with 1928 patients receiving metformin-based regimens, 964 patients receiving SGLT2 inhibitor-based regimens had similar all-cause mortality (hazard ratio [HR], 0.75 [95% CI, 0.51-1.12]), cardiovascular death (HR, 0.69 [95% CI, 0.25-1.89]), hospitalization for heart failure (HR, 1.06 [95% CI, 0.59-1.92]), stroke (HR, 0.78 [95% CI, 0.48-1.27]), and progression to end-stage renal disease (HR, 0.88 [95% CI, 0.32-2.39]). However, SGLT2 inhibitors were associated with a lower risk of all-cause mortality (HR, 0.47 [95% CI, 0.23-0.99]; Conclusions: In comparison to metformin-based regimens, SGLT2 inhibitor-based regimens showed a similar risk of all-cause mortality and adverse cardiorenal events. SGLT2 inhibitors might be considered as first-line therapy in select low-risk patients, for example, younger patients with diabetes.
MeSH term(s)	Male ; Humans ; Middle Aged ; Aged ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Metformin/therapeutic use ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Cohort Studies ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Cardiovascular Diseases/chemically induced ; Risk Factors ; Treatment Outcome ; Heart Failure/epidemiology ; Heart Failure/chemically induced ; Kidney Failure, Chronic ; Heart Disease Risk Factors ; Stroke/chemically induced ; Glucose ; Hypoglycemic Agents/therapeutic use
Chemical Substances	Sodium-Glucose Transporter 2 Inhibitors ; Metformin (9100L32L2N) ; Glucose (IY9XDZ35W2) ; Hypoglycemic Agents
Language	English
Publishing date	2024-04-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2653953-6
ISSN	2047-9980 ; 2047-9980
ISSN (online)	2047-9980
ISSN	2047-9980
DOI	10.1161/JAHA.123.032397
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Article ; Online: Steric Effects on the Photovoltaic Performance of Panchromatic Ruthenium Sensitizers for Dye-Sensitized Solar Cells.

Chen, Chia-Yuan / Lin, Ting-Yi / Chiu, Chi-Feng / Lee, Mandy M / Li, Wei-Long / Chen, Min-Yu / Hung, Tzu-Hao / Zhang, Zhao-Jie / Tsai, Hui-Hsu Gavin / Sun, Shih-Sheng / Wu, Chun-Guey

ACS applied materials & interfaces

2024 Volume 16, Issue 10, Page(s) 12647–12660

Abstract: Three new heteroleptic Ru complexes, ...

Abstract	Three new heteroleptic Ru complexes,
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c19298
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