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  1. Article: Diagnosis of early oral and oropharyngeal squamous carcinoma: obstacles and their amelioration.

    Mashberg, A

    Oral oncology

    2000  Volume 36, Issue 3, Page(s) 253–255

    MeSH term(s) Carcinoma, Squamous Cell/diagnosis ; Humans ; Mouth Mucosa ; Mouth Neoplasms/diagnosis ; Oropharyngeal Neoplasms/diagnosis ; Precancerous Conditions/diagnosis ; Sensitivity and Specificity ; Staining and Labeling ; Tolonium Chloride
    Chemical Substances Tolonium Chloride (15XUH0X66N)
    Language English
    Publishing date 2000-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 1368-8375 ; 0964-1955
    ISSN (online) 1879-0593
    ISSN 1368-8375 ; 0964-1955
    DOI 10.1016/s1368-8375(00)00006-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Toluidine blue.

    Mashberg, A

    Journal (Canadian Dental Association)

    1995  Volume 61, Issue 11, Page(s) 922, 944

    MeSH term(s) Carcinoma, Squamous Cell/diagnosis ; Coloring Agents ; Erythroplasia/diagnosis ; False Positive Reactions ; Humans ; Mouth Neoplasms/diagnosis ; Tolonium Chloride
    Chemical Substances Coloring Agents ; Tolonium Chloride (15XUH0X66N)
    Language English
    Publishing date 1995-11
    Publishing country Canada
    Document type Comment ; Letter
    ZDB-ID 604786-5
    ISSN 1488-2159 ; 0709-8936 ; 0008-3372
    ISSN (online) 1488-2159
    ISSN 0709-8936 ; 0008-3372
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  3. Article: Head and neck cancer.

    Mashberg, A

    The New England journal of medicine

    1993  Volume 328, Issue 24, Page(s) 1783; author reply 1784

    MeSH term(s) Cell Transformation, Neoplastic ; Erythroplasia/pathology ; Head and Neck Neoplasms ; Humans ; Mouth Neoplasms/pathology
    Language English
    Publishing date 1993-06-17
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJM199306173282412
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  4. Article: Re: Oral cavity cancer in non-users of tobacco.

    Mashberg, A

    Journal of the National Cancer Institute

    1993  Volume 85, Issue 18, Page(s) 1525

    MeSH term(s) Alcohol Drinking ; Beer ; Humans ; Mouth Neoplasms/etiology ; Nitrosamines ; Smoking
    Chemical Substances Nitrosamines
    Language English
    Publishing date 1993-09-15
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 2992-0
    ISSN 1460-2105 ; 0027-8874 ; 0198-0157
    ISSN (online) 1460-2105
    ISSN 0027-8874 ; 0198-0157
    DOI 10.1093/jnci/85.18.1525-a
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  5. Article: Asymptomatic early invasive carcinoma.

    Mashberg, A

    Oral surgery, oral medicine, and oral pathology

    1985  Volume 59, Issue 2, Page(s) 174–175

    MeSH term(s) Carcinoma/pathology ; Erythroplasia/pathology ; Humans ; Mouth Neoplasms/pathology ; Neoplasm Invasiveness ; Time Factors
    Language English
    Publishing date 1985-02
    Publishing country United States
    Document type Letter
    ZDB-ID 202468-8
    ISSN 1528-395X ; 0030-4220 ; 1079-2104
    ISSN (online) 1528-395X
    ISSN 0030-4220 ; 1079-2104
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  6. Article: Toluidine blue staining in the detection of oral precancerous and malignant lesions.

    Mashberg, A

    Oral surgery, oral medicine, and oral pathology

    1984  Volume 58, Issue 4, Page(s) 401

    MeSH term(s) Humans ; Mouth Neoplasms/diagnosis ; Precancerous Conditions/diagnosis ; Tolonium Chloride
    Chemical Substances Tolonium Chloride (15XUH0X66N)
    Language English
    Publishing date 1984-10
    Publishing country United States
    Document type Letter
    ZDB-ID 202468-8
    ISSN 1528-395X ; 0030-4220 ; 1079-2104
    ISSN (online) 1528-395X
    ISSN 0030-4220 ; 1079-2104
    DOI 10.1016/0030-4220(84)90332-3
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  7. Article: Final evaluation of tolonium chloride rinse for screening of high-risk patients with asymptomatic squamous carcinoma.

    Mashberg, A

    Journal of the American Dental Association (1939)

    1983  Volume 106, Issue 3, Page(s) 319–323

    MeSH term(s) Carcinoma, Squamous Cell/diagnosis ; Diagnostic Errors ; Evaluation Studies as Topic ; Humans ; Mouth Neoplasms/diagnosis ; Mouthwashes ; Tolonium Chloride/administration & dosage
    Chemical Substances Mouthwashes ; Tolonium Chloride (15XUH0X66N)
    Language English
    Publishing date 1983-03
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 220622-5
    ISSN 1943-4723 ; 0002-8177 ; 1048-6364
    ISSN (online) 1943-4723
    ISSN 0002-8177 ; 1048-6364
    DOI 10.14219/jada.archive.1983.0063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Clinical stains for cancer.

    Mashberg, A

    Lancet (London, England)

    1982  Volume 1, Issue 8273, Page(s) 680

    MeSH term(s) False Positive Reactions ; Humans ; Neoplasms/diagnosis ; Staining and Labeling/methods
    Language English
    Publishing date 1982-03-20
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0140-6736 ; 0023-7507
    ISSN (online) 1474-547X
    ISSN 0140-6736 ; 0023-7507
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  9. Article: Toluidine blue--viewpoints.

    Ephros, H / Mashberg, A

    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics

    1999  Volume 87, Issue 5, Page(s) 526–7; author reply 528–9

    MeSH term(s) Carcinoma, Squamous Cell/diagnosis ; Coloring Agents ; Humans ; Mouth Neoplasms/diagnosis ; Tolonium Chloride
    Chemical Substances Coloring Agents ; Tolonium Chloride (15XUH0X66N)
    Language English
    Publishing date 1999-05
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 202468-8
    ISSN 1528-395X ; 1079-2104 ; 0030-4220
    ISSN (online) 1528-395X
    ISSN 1079-2104 ; 0030-4220
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  10. Article: Tolonium (toluidine blue) rinse--a screening method for recognition of squamous carcinoma. Continuing study of oral cancer IV.

    Mashberg, A

    JAMA

    1981  Volume 245, Issue 23, Page(s) 2408–2410

    Abstract: Tolonium chloride (toluidine blue) application is useful for identifying malignant changes in squamous mucosa. However, early asymptomatic mucosal changes may remain undetected by tolonium application. A study was carried out to determine the feasibility ...

    Abstract Tolonium chloride (toluidine blue) application is useful for identifying malignant changes in squamous mucosa. However, early asymptomatic mucosal changes may remain undetected by tolonium application. A study was carried out to determine the feasibility of using a tolonium mouth rinse as a routine procedure after thorough clinical examination, to discover undetected cancers. A proved, effective tolonium application method was compared with a rinse sequence. One hundred five asymptomatic oral lesions (51 carcinomas and 54 nonmalignant lesions) that persisted for ten to 14 days were evaluated with application and rinse modalities and biopsies. There were 2% false-negatives (1/51) with the application as opposed to 5.9% (3/51) with the rinse and 9.3% false-positives (5/54) with the application as compared to 7.4% (4/54) with the rinse. Four inapparent, second primary cancers, unobserved for application, were delineated by the rinse (three oral, one pharyngeal). Tolonium blue rinse may be used to detect unobserved, asymptomatic oral mucosal cancers after clinical examination. After a positive rinse stain, a subsequent positive application stain ten to 14 days later mandates a biopsy of the lesion.
    MeSH term(s) Carcinoma, Squamous Cell/diagnosis ; False Negative Reactions ; False Positive Reactions ; Humans ; Mouth Mucosa/pathology ; Mouth Neoplasms/diagnosis ; Staining and Labeling/methods ; Tolonium Chloride/administration & dosage
    Chemical Substances Tolonium Chloride (15XUH0X66N)
    Language English
    Publishing date 1981-06-19
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0098-7484 ; 0254-9077 ; 0002-9955
    ISSN (online) 1538-3598
    ISSN 0098-7484 ; 0254-9077 ; 0002-9955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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